Benzoyl peroxide/clindamycin/UVA is more effective than fluticasone/UVA in progressive macular hypomelanosis: a randomized study.

abstract：BACKGROUND:Several studies have found that the microbiota of psoriatic lesions is different from that of healthy skin. OBJECTIVE:To characterize the microbiota of lesional and unaffected skin in patients with psoriasis and controls and investigate the correlation between cutaneous microbiota and clinical features of p...

journal_title：Journal of the American Academy of Dermatology

authors： Quan C,Chen XY,Li X,Xue F,Chen LH,Liu N,Wang B,Wang LQ,Wang XP,Yang H,Zheng J

更新日期：2020-04-01 00:00:00

abstract：BACKGROUND:Recombinant human platelet derived growth factor-BB gel (PDGF gel) has been shown to be effective in the treatment of diabetic neuropathic ulcers. It is also being used off-label to speed wound healing of flaps, grafts, and wounds from Mohs micrographic surgery. OBJECTIVE:The purpose of the study was to com...

journal_title：Journal of the American Academy of Dermatology

authors： Cohen MA,Eaglstein WH

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:After oral intake, 5-methoxypsoralen (5-MOP) is as effective as 8-MOP for PUVA therapy for psoriasis, with a lower incidence of acute cutaneous side effects. OBJECTIVE:We compared bath-water delivery of 5-MOP and 8-MOP for photochemotherapy of psoriasis. METHODS:Twenty-two patients underwent phototesting w...

journal_title：Journal of the American Academy of Dermatology

authors： Calzavara-Pinton PG,Zane C,Carlino A,De Panfilis G

更新日期：1997-06-01 00:00:00

abstract：:Levels of IgE antibodies to Staphylococcus aureus and Staphylococcus epidermidis were determined in eleven patients with typical atopic dermatitis, with no history of furuncles or severe staphylococcal infection. Increased IgE binding to S. aureus but not to S. epidermidis was observed. Fifteen patients with hyperimmu...

journal_title：Journal of the American Academy of Dermatology

authors： Abramson JS,Dahl MV,Walsh G,Blumenthal MN,Douglas SD,Quie PG

更新日期：1982-07-01 00:00:00

abstract：:Two families with anetoderma are described. Unlike previous reports of familial anetoderma, the disease process seemed to be limited to the skin, and there were no associated ocular, gastrointestinal, or orthopedic anomalies in the affected patients or in any other family members. Although infrequently reported, aneto...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman SJ,Venencie PY,Bradley RR,Winkelmann RK

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Retrospective data have suggested the effectiveness of intravenous immunoglobulins (IVIG) for solar urticaria (SU). OBJECTIVE:We sought to prospectively assess the efficacy of IVIG for SU. METHODS:We conducted a multicentric phase II study to test the efficacy of a single course of IVIG (2 g/kg) in patient...

journal_title：Journal of the American Academy of Dermatology

authors： Aubin F,Porcher R,Jeanmougin M,Léonard F,Bedane C,Moreau A,Schmutz JL,Marguery MC,Adamski H,Viguier M,Société Française de Photodermatologie.

更新日期：2014-11-01 00:00:00

abstract：:Pathologic T-cell activation is implicated in psoriasis progression. CD80, a costimulatory molecule involved in T-cell activation, likely plays a key role. IDEC-114, an IgG(1) anti-CD80 antibody, was evaluated for safety, pharmacokinetics, and preliminary clinical activity in this open-label, single-dose, dose-escalat...

journal_title：Journal of the American Academy of Dermatology

authors： Gottlieb AB,Lebwohl M,Totoritis MC,Abdulghani AA,Shuey SR,Romano P,Chaudhari U,Allen RS,Lizambri RG

更新日期：2002-11-01 00:00:00

abstract：:Fibrous harmartoma of infancy is a benign soft tissue tumor that occurs in the first few years of life. Although the lesion is not distinctive clinically, it has a characteristic microscopic appearance. Only 12 cases of fibrous hamartoma of infancy have been reported in the dermatology literature. ...

journal_title：Journal of the American Academy of Dermatology

authors： Scott DM,Peña JR,Omura EF

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:Physicians are important in the early detection of melanoma. We investigated whether primary care physician supply and the supply of dermatologists were related to stage at diagnosis for malignant melanoma. METHODS:From the state tumor registry in Florida in 1994, we identified incident cases of malignant m...

journal_title：Journal of the American Academy of Dermatology

authors： Roetzheim RG,Pal N,van Durme DJ,Wathington D,Ferrante JM,Gonzalez EC,Krischer JP

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:The risk of acquiring Lyme disease has been evaluated by xenodiagnostic procedures with laboratory strains of Borrelia burgdorferi and laboratory-reared Ixodes ticks, or by clinical trials in which diagnosis was based on clinical findings, culture, or serologic tests. OBJECTIVE:Our purpose was to determine ...

journal_title：Journal of the American Academy of Dermatology

authors： Berger BW,Johnson RC,Kodner C,Coleman L

更新日期：1995-02-01 00:00:00

abstract：BACKGROUND:Interferon-alfa (IFN-alpha) has been implicated in the pathogenesis of psoriasis. OBJECTIVE:To evaluate the safety profile of MEDI-545, a fully human anti-IFN-alpha monoclonal antibody and to explore its effect on the involvement of type I IFN-alpha activity in the maintenance of established plaque psoriasi...

journal_title：Journal of the American Academy of Dermatology

authors： Bissonnette R,Papp K,Maari C,Yao Y,Robbie G,White WI,Le C,White B

更新日期：2010-03-01 00:00:00

abstract：:Granuloma annulare typically affects the hands and the feet, sparing the volar surfaces. A case of granuloma annulare localized to the palms is described. ...

journal_title：Journal of the American Academy of Dermatology

authors： Hsu S,Lehner AC,Chang JR

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:It is unclear whether the type 2 T helper cell-specific immunosuppressive action of dupilumab interferes with patch testing. OBJECTIVES:We sought to evaluate the reliability of patch testing on dupilumab and the contribution of allergic contact dermatitis (ACD) to complex dermatitis in patients with residua...

journal_title：Journal of the American Academy of Dermatology

authors： Raffi J,Suresh R,Botto N,Murase JE

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Vulvar lichen sclerosus is a chronic condition usually responsive to topical corticosteroids. OBJECTIVE:We sought to evaluate the efficacy (reduction of signs and symptoms) and safety of clobetasol propionate 0.05% and tacrolimus 0.1% in the treatment of vulvar lichen sclerosus. METHOD:This double-blind, r...

journal_title：Journal of the American Academy of Dermatology

authors： Funaro D,Lovett A,Leroux N,Powell J

更新日期：2014-07-01 00:00:00

abstract：:The usual method of treatment of pilomatricoma (calcifying epitheliona of Malherbe) is excision. We present a review of eight patients with ten tumors treated by incision and curettement. Follow-up ranged from 1 to 10 years, and there have been no recurrences. An alternative method of therapy with excellent results is...

journal_title：Journal of the American Academy of Dermatology

authors： Morales A,McGoey J

更新日期：1980-01-01 00:00:00

abstract：:The advent of new topical agents such as topical calcineurin inhibitors, as well as the reformulations of older agents in new vehicles, has broadened the treatment approaches to psoriasis and atopic dermatitis. The clinician must now consider additional novel physiologic pathways and mechanisms of action as well as ex...

journal_title：Journal of the American Academy of Dermatology

authors： Norris DA

更新日期：2005-07-01 00:00:00

abstract：:The PA Patch, a new multiple-antigen, predispensed patch testing device, was compared to the Finn Chamber in subjects with previous positive patch tests. After pressing the PA Patch well, the PA Patch performed as well as the Finn Chamber in nine subjects tested. ...

journal_title：Journal of the American Academy of Dermatology

authors： Marks JG Jr,Westheim A,Snipes W

更新日期：1987-05-01 00:00:00

abstract：:Cutaneous leishmaniasis (oriental sore) is characterized by slowly evolving inflammatory lesion(s) that are nodular, noduloulcerative, or ulcerative and that heal spontaneously with scar(s) in 3 to 12 months. In the course of a comprehensive study of cutaneous leishmaniasis due to Leishmania major in an endemic focus ...

journal_title：Journal of the American Academy of Dermatology

authors： Kubba R,Al-Gindan Y,el-Hassan AM,Omer AH

更新日期：1987-06-01 00:00:00

abstract：:A survey of dermatologic training centers in the United States and Canada discloses that only 12% use conventional x-ray therapy intramurally and an additional 15% utilize grenz ray therapy. Although many refer patients to radiologists on a regular basis, half of the present training programs consider radiation therap...

journal_title：Journal of the American Academy of Dermatology

authors： Kingery FA

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Basaloid squamous cell carcinoma (BSCC), an aggressive tumor of the aerodigestive tract, was described over 20 years ago, and its defining histologic parameters remain largely unchanged. While rare reports have noted cutaneous metastatic deposition, primary tumors have not been previously described. OBJECTI...

journal_title：Journal of the American Academy of Dermatology

authors： Boyd AS,Stasko TS,Tang YW

更新日期：2011-01-01 00:00:00

abstract：BACKGROUND:In 1982 we reported our preliminary observations on the use of home UV phototherapy for patch and early plaque phase mycosis fungoides (MF). OBJECTIVE:Our purpose was to present follow-up data of the original 31 patients, covering an interval of up to 15 years. METHODS:All patients used a commercially avai...

journal_title：Journal of the American Academy of Dermatology

authors： Resnik KS,Vonderheid EC

更新日期：1993-07-01 00:00:00

abstract：:Lupus pernio has been associated with sarcoidosis of the upper respiratory tract. The semantic differences in the use of the designation "lupus pernio" are such that American dermatologists may not consider patients with nasal rim papules of sarcoidosis to have lupus pernio. During a 12-month period, we referred each ...

journal_title：Journal of the American Academy of Dermatology

authors： Jorizzo JL,Koufman JA,Thompson JN,White WL,Shar GG,Schreiner DJ

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Vitiligo is an autoimmune disease of the skin with limited treatment options; there is an urgent need to identify and validate biomarkers of disease activity to support vitiligo clinical studies. OBJECTIVE:To investigate potential biomarkers of disease activity directly in the skin of vitiligo subjects and ...

journal_title：Journal of the American Academy of Dermatology

authors： Strassner JP,Rashighi M,Ahmed Refat M,Richmond JM,Harris JE

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:The hazards of acute radiation exposure are well known. Bone marrow failure from total body gamma or neutron irradiation is the most clinically relevant aspect of acute radiation disease. With nonhomogeneous exposure, as is characteristic in accidents, other organ systems, such as the skin, may be more impor...

journal_title：Journal of the American Academy of Dermatology

authors： Peter RU,Braun-Falco O,Birioukov A,Hacker N,Kerscher M,Peterseim U,Ruzicka T,Konz B,Plewig G

更新日期：1994-05-01 00:00:00

abstract：UNLABELLED:Skin cancer is the most common cancer in human beings. The increased incidence of skin cancer has brought much attention to the process by which these tumors develop and how they can be prevented. Efforts have been made to educate the public about the importance of protecting skin from excessive ultraviolet ...

journal_title：Journal of the American Academy of Dermatology

authors： Wright TI,Spencer JM,Flowers FP

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:Dermatophytic infections of the fingernail can be effectively treated with oral antifungal agents; however, a long duration of treatment, generally several months, is required for cure. OBJECTIVE:Our purpose was to compare the efficacies of short-duration treatment with terbinafine and griseofulvin in the m...

journal_title：Journal of the American Academy of Dermatology

authors： Haneke E,Tausch I,Bräutigam M,Weidinger G,Welzel D

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:There are multiple therapeutic options for the treatment of moderate to severe psoriasis. The process of choosing among potential treatment options requires both the physician and the patient to weigh the benefits of individual modalities against their potential risks. Traditional systemic therapies for psor...

journal_title：Journal of the American Academy of Dermatology

authors： Patel RV,Clark LN,Lebwohl M,Weinberg JM

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Pseudoxanthoma elasticum (PXE) is a systemic connective tissue disorder involving elastic fiber calcification and fragmentation with major clinical manifestations occurring in the cutaneous, ocular, and cardiovascular systems. Normalization of the serum calcium-phosphate product through hemodialysis in a pre...

journal_title：Journal of the American Academy of Dermatology

authors： Sherer DW,Singer G,Uribarri J,Phelps RG,Sapadin AN,Freund KB,Yanuzzi L,Fuchs W,Lebwohl M

更新日期：2005-10-01 00:00:00

abstract：:Human immunodeficiency virus (HIV) infection in children has emerged as a major, rapidly growing public health problem. The majority of children become infected by perinatal transmission of the virus from an infected mother. The disease is frequently associated with progressive neurologic dysfunction and with opportun...

journal_title：Journal of the American Academy of Dermatology

authors： Prose NS

更新日期：1990-06-01 00:00:00

abstract：:Angioedema is characterized by localized swelling of sudden onset affecting the skin and/or mucous membranes. It can be classified into hereditary and acquired forms. Hereditary angioedema is a rare disease inherited as an autosomal dominant trait and caused by a deficiency of C1-esterase inhibitor. Acute attacks are ...

journal_title：Journal of the American Academy of Dermatology

authors： Greaves M,Lawlor F

更新日期：1991-07-01 00:00:00