The pathogenesis of psoriasis and the mechanism of action of tazarotene.

abstract：:The acute complications that may result in failure of the surgical procedure are discussed. These include bleeding, hematoma, infection, dehiscence, and necrosis. The background of each is covered in detail and an attempt is made to show the interrelationships among them. The purpose of this communication is to aid in...

journal_title：Journal of the American Academy of Dermatology

authors： Salasche SJ

更新日期：1986-12-01 00:00:00

abstract：:"Poikiloderma" is a morphologic and descriptive term referring to a combination of cutaneous atrophy, telangiectasia, and varied macular pigmentary changes that result in a mottled skin appearance. Its etiology includes both congenital and acquired causes. Many studies have reported different causes of acquired poikil...

journal_title：Journal of the American Academy of Dermatology

authors： Nofal A,Salah E

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Dermatomyositis (DM) is a multisystem autoimmune disease, in which serologic evidence of immune responses to disease-specific antigenic targets is found in approximately 50% to 70% of patients. Recently, melanoma differentiation-associated gene 5 (MDA5) has been identified as a DM-specific autoantigen that a...

journal_title：Journal of the American Academy of Dermatology

authors： Fiorentino D,Chung L,Zwerner J,Rosen A,Casciola-Rosen L

更新日期：2011-07-01 00:00:00

abstract：:A 46-year-old albino woman is described with a melanoma on the leg from which a punch biopsy specimen was inadvertently taken. In the reexcision specimen, two biopsy wounds were recognized that were filled with tumor. The initial level III lesion had to be subsequently reported as a deep level IV amelanotic melanoma w...

journal_title：Journal of the American Academy of Dermatology

authors： van der Esch EP,Rampen FH

更新日期：1985-11-01 00:00:00

abstract：:The deep penetrating nevus (DPN), also known as the plexiform spindle cell nevus, is a pigmented lesion that commonly arises on the head and neck in the first few decades of life. Histopathologically, the DPN is wedge-shaped and contains melanocytes that exhibit deep infiltration into the dermis. Given these features,...

journal_title：Journal of the American Academy of Dermatology

authors： Strazzula L,Senna MM,Yasuda M,Belazarian L

更新日期：2014-12-01 00:00:00

abstract：:Twenty undifferentiated skin tumors were examined by immunostaining in an attempt to achieve more precise identification. Light microscopy yielded only a differential diagnosis, whereas immunostaining of formalin-fixed, paraffin-embedded tissue sections with a panel of antibodies to intermediate filaments and other ce...

journal_title：Journal of the American Academy of Dermatology

authors： Kahn H,Baumal R,From L

更新日期：1986-06-01 00:00:00

abstract：:The most common active ingredient in hair coloring is para-phenylenediamine (PPDA), which can produce contact dermatitis, particularly in persons who dye their scalp hair and in hairdressers. We have identified another group of patients also at risk, namely men from Arab countries, who commonly grow beards and dye the...

journal_title：Journal of the American Academy of Dermatology

authors： Hsu TS,Davis MD,el-Azhary R,Corbett JF,Gibson LE

更新日期：2001-05-01 00:00:00

abstract：BACKGROUND:Cidofovir is a potent nucleoside analog antiviral drug approved for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It is currently available only for intravenous infusion. Several small studies and case reports describe the successful use of cidofovir applied either topically or intr...

journal_title：Journal of the American Academy of Dermatology

authors： Zabawski EJ Jr,Cockerell CJ

更新日期：1998-11-01 00:00:00

abstract：BACKGROUND:Tinea corporis gladiatorum has been an infrequently reported condition in the dermatological literature. Two previous reports have investigated wrestlers during recognized epidemics of tinea corporis gladiatorum, but no study has examined wrestlers to determine the point prevalence of tinea corporis gladiato...

journal_title：Journal of the American Academy of Dermatology

authors： Adams BB

更新日期：2000-12-01 00:00:00

abstract：:Hyperpigmentation of the skin is often refractory to conventional therapies, but has significant cosmetic implications if located on visible areas. Because laser systems are capable of removing pigment deposits caused by selective photothermolysis, we addressed the issue of whether the Q-switched ruby laser could be a...

journal_title：Journal of the American Academy of Dermatology

authors： Becker-Wegerich PM,Kuhn A,Malek L,Lehmann P,Megahed M,Ruzicka T

更新日期：2000-08-01 00:00:00

abstract：:Skin biopsy specimens from 24 patients with different lichenoid skin diseases that had been proved histologically were studied immunohistologically. Marked differences were noted in the number of OKT6+/S100+ Langerhans cells within the epidermis and dermis in the lesional skin between lichen planus (and its related di...

journal_title：Journal of the American Academy of Dermatology

authors： Shiohara T,Moriya N,Tanaka Y,Arai Y,Hayakawa J,Chiba M,Nagashima M

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Lack of agreement on how to accurately capture disease outcomes in localized scleroderma (LS) has hindered the development of efficacious treatment protocols. The LS Cutaneous Assessment Tool (LoSCAT), consisting of the modified LS Skin Severity Index (mLoSSI) and the LS Damage Index, has potential for use i...

journal_title：Journal of the American Academy of Dermatology

authors： Kelsey CE,Torok KS

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Focal atrichia is a common clinical finding in female pattern hair loss, the specificity and histologic findings of which need further clarification. OBJECTIVE:To determine the frequency of focal atrichia in various types of hair loss and its histologic characteristics in female pattern hair loss. METHODS:...

journal_title：Journal of the American Academy of Dermatology

authors： Olsen EA,Whiting DA

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:CD2- CD4+ CD56+ lymphoid malignancy has been only rarely reported the last 5 years. It is characterized by a high incidence of cutaneous involvement, cytologically agranular cells, aggressive clinical course, and negative Epstein-Barr virus (EBV) involvement. OBSERVATION:We describe a Japanese patient with ...

journal_title：Journal of the American Academy of Dermatology

authors： Kato N,Yasukawa K,Kimura K,Sugawara H,Aoyagi S,Mishina T,Nakata T

更新日期：2001-02-01 00:00:00

abstract：:Nonsteroidal anti-inflammatory drugs have been shown to inhibit inflammation, an integral part of the wound-healing process. Compromised wound repair has been demonstrated in laboratory animals administered high-dose nonsteroidal anti-inflammatory drugs, a phenomenon we speculate could occur in humans undergoing surge...

journal_title：Journal of the American Academy of Dermatology

authors： Proper SA,Fenske NA,Burnett SM,Luria LW

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:Wide-ranging prevalence estimates of psoriatic arthritis (PsA) in patients with psoriasis have been reported. OBJECTIVES:To assess the prevalence and incidence of PsA in patients with psoriasis. METHODS:Two authors independently searched 3 databases for studies reporting on the prevalence or incidence of P...

journal_title：Journal of the American Academy of Dermatology

authors： Alinaghi F,Calov M,Kristensen LE,Gladman DD,Coates LC,Jullien D,Gottlieb AB,Gisondi P,Wu JJ,Thyssen JP,Egeberg A

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Surgeons use absorbable and nonabsorbable sutures for epidermal wound closure. No large, randomized studies have compared the effect of these suture types on facial scar appearance. OBJECTIVE:To assess postsurgical facial scar appearance using either rapidly absorbable polyglactin 910 or nylon for epidermal...

journal_title：Journal of the American Academy of Dermatology

authors： Moran B,Humphrey S,Seal A,Berkowitz J,Zloty D

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Clinical and histopathologic features of childhood melanoma are poorly characterized. Atypical clinical presentations and ambiguous microscopic findings may contribute to diagnostic delays. OBJECTIVES:We sought to determine whether conventional ABCDE melanoma detection criteria (Asymmetry, Border irregulari...

journal_title：Journal of the American Academy of Dermatology

authors： Cordoro KM,Gupta D,Frieden IJ,McCalmont T,Kashani-Sabet M

更新日期：2013-06-01 00:00:00

abstract：:Psychosomatic dermatology is practiced in some manner by every dermatologist. In spite of this, there has been a virtual void in the literature from the middle 1950s until the present time. The relationship to physiologic phenomena, as well as a classification of psychosomatic dermatology, is reviewed. Dermatologic pa...

journal_title：Journal of the American Academy of Dermatology

authors： Medansky RS,Handler RM

更新日期：1981-08-01 00:00:00

abstract：:Pressure ulcers are localized areas of tissue necrosis that result from unrelieved pressure. They are graded or staged according to the degree of tissue damage observed. The main etiologic factors include pressure, shearing forces, friction, and moisture. The clinical course may be complicated by several conditions in...

journal_title：Journal of the American Academy of Dermatology

authors： Kanj LF,Wilking SV,Phillips TJ

更新日期：1998-04-01 00:00:00

abstract：:We describe a female patient with an acute purpuric and bullous eruption mainly affecting the lower aspect of the legs. Skin biopsy specimens demonstrated microvascular occlusions with fibrin thrombi but no dermal inflammation. Intermediate hyperhomocysteinemia and transient antiphospholipid antibodies were evidenced ...

journal_title：Journal of the American Academy of Dermatology

authors： Martin L,Armingaud P,Georgescu V,Matre F,Legac E,Estève E

更新日期：2003-08-01 00:00:00

abstract：:Pain is a central component of illness and suffering, yet unfortunately it is frequently undertreated. In dermatology, many acute and chronic conditions are characterized by pain that may require therapeutic intervention in addition to medical treatment aimed at treating the primary disease. To date, however, there ar...

journal_title：Journal of the American Academy of Dermatology

authors： Enamandram M,Rathmell JP,Kimball AB

更新日期：2015-10-01 00:00:00

abstract：:Cytodestructive or surgical therapy for patients with anogenital warts is frequently associated with recurrence. In February 1997, the US Food and Drug Administration approved imiquimod as a 5% cream for the treatment of anogenital warts. Activity of the drug results primarily from interferon alfa and other cytokine i...

journal_title：Journal of the American Academy of Dermatology

authors： Carrasco D,vander Straten M,Tyring SK

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Kaposi varicelliform eruption (KVE), or herpes simplex virus (HSV) superinfection of pre-existing skin lesions, may complicate Darier disease. OBJECTIVE:We sought to compare the clinical features and outcomes of patients with Darier disease who developed KVE superinfection with those who did not. METHODS:A...

journal_title：Journal of the American Academy of Dermatology

authors： Vogt KA,Lohse CM,El-Azhary RA,Gibson LE,Lehman JS

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Alcohol consumption and smoking have long been suspected of increasing the risk of developing psoriasis. Most evidence to date has derived from cross-sectional or case-control studies. OBJECTIVE:We sought to investigate the effects of alcohol and smoking on incident psoriasis. METHODS:Alcohol consumption, ...

journal_title：Journal of the American Academy of Dermatology

authors： Dai YX,Wang SC,Chou YJ,Chang YT,Chen TJ,Li CP,Wu CY

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND:The efficacy of the skin self-examination (SSE) to detect artificial changes in the size of nevi has not been evaluated in a controlled setting. OBJECTIVE:Our purpose was to determine the sensitivity and specificity of the SSE in detecting artificial changes in mole size in patients at high risk for melanom...

journal_title：Journal of the American Academy of Dermatology

authors： Muhn CY,From L,Glied M

更新日期：2000-05-01 00:00:00

abstract：:We describe a patient with vitamin A deficiency phrynoderma caused by a combination of inadequate dietary intake of vitamin A and beta-carotene and malabsorption secondary to primary visceral myopathy and total colectomy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Bleasel NR,Stapleton KM,Lee MS,Sullivan J

更新日期：1999-08-01 00:00:00

abstract：:In 1987 the American Academy of Dermatology began to create Guidelines of Care for clinical disease processes in dermatology. The format of the guidelines has changed dramatically over the past several years; now all of the recent guidelines are in the evidence-based style. These guidelines have been recognized nation...

journal_title：Journal of the American Academy of Dermatology

authors： Van Voorhees AS

更新日期：2003-06-01 00:00:00

abstract：:Conventional chemotherapy continues to be an important part of cancer management, but may cause various cutaneous reactions because it disturbs specific cell cycle phases. The alkylating agents cyclophosphamide, ifosfamide, and thiotepa can produce hyperpigmentation, while hypersensitivity reactions can be seen with p...

journal_title：Journal of the American Academy of Dermatology

authors： Reyes-Habito CM,Roh EK

更新日期：2014-08-01 00:00:00

abstract：BACKGROUND:The antioxidants selenium and vitamin E can be effective in reducing acute and chronic ultraviolet (UV)-induced skin damage. OBJECTIVE:This study investigated whether topical L-selenomethionine with topical RRR-alpha-tocopherol (Eol) or oral RRR-alpha-tocopheryl acetate (Eac) can reduce the incidence of UV-...

journal_title：Journal of the American Academy of Dermatology

authors： Burke KE,Clive J,Combs GF Jr,Nakamura RM

更新日期：2003-09-01 00:00:00