Abstract:
:It is often stated that persons of Celtic origin have an increased risk of skin cancer, but the evidence for this is almost exclusively anecdotal. We believe that the possibility of the Celts being at greater risk of skin cancer has important implications with regard to management in particular and in assisting our understanding of carcinogenesis in general. For these reasons we have reviewed all those studies implicating Celtic ancestry in the development of both malignant melanoma and nonmelanoma skin cancer.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Long CC,Marks Rdoi
10.1016/0190-9622(95)91289-4subject
Has Abstractpub_date
1995-10-01 00:00:00pages
658-61issue
4eissn
0190-9622issn
1097-6787pii
0190-9622(95)91289-4journal_volume
33pub_type
杂志文章,评审abstract:BACKGROUND:It is important for dermatologists and other physicians in refugee-receiving countries to acquire knowledge of forensic dermatology to identify lesions from torture. OBJECTIVE:Review forensic dermatology in cases of torture. RESULTS:In providing medical assessment and care to refugees and migrants, chronic...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2020.09.031
更新日期:2020-09-15 00:00:00
abstract::Striking results were obtained with oral itraconazole therapy in two opportunistic mycoses. Of 28 patients with cryptococcal meningitis, 18 achieved complete responses, including 16 of 24 patients with acquired immunodeficiency syndrome. Other manifestations of cryptococcosis were similarly responsive. In aspergillosi...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(90)70262-g
更新日期:1990-09-01 00:00:00
abstract::Melanomas are rare in patients who have albinism, compared with the frequent occurrence of squamous cell carcinomas and basal cell carcinomas. This report describes amelanotic metastatic melanoma in a 58-year-old Japanese man who had tyrosinase-positive oculocutaneous albinism. A prolonged bleeding time, facioscapuloh...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/0190-9622(93)70128-g
更新日期:1993-05-01 00:00:00
abstract:BACKGROUND:Atypical fibroxanthoma (AFX) is a fibrohistiocytic tumor with relatively high local recurrence rates but low metastatic potential. Wide local excision (WLE) and Mohs micrographic surgery (MMS) are common treatments, although no consensus exists regarding optimal therapy. OBJECTIVE:To systematically review e...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,meta分析
doi:10.1016/j.jaad.2018.06.048
更新日期:2018-11-01 00:00:00
abstract::The term Richter syndrome (RS) describes the transformation of chronic lymphocytic leukemia into a high-grade lymphoma. RS occurs in 3% to 10% of chronic lymphocytic leukemia cases, and its onset is often characterized by the abrupt development of systemic symptoms (eg, fever in the absence of infection, night sweats,...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2008.07.017
更新日期:2009-01-01 00:00:00
abstract::Pustular cutaneous vasculitis results from a heterogeneous group of disorders characterized by pustules on purpuric bases. Although the cause of this group of conditions is diverse, the histopathologic picture of the lesions is the same, showing a Sweet's-like or leukocytoclastic vasculitis. These distinctive lesions ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(86)70116-3
更新日期:1986-05-01 00:00:00
abstract:BACKGROUND:Pemphigus vulgaris (PV) shows autoimmune reaction against desmoglein 3 (Dsg3), whereas paraneoplastic pemphigus (PNP) shows autoimmune reaction against Dsg3 as well as numerous members of the plakin family. It has been demonstrated that in PV, dominant epitopes reside in N-terminal adhesive regions of Dsg3 a...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(03)02160-1
更新日期:2003-12-01 00:00:00
abstract:BACKGROUND:Cutaneous polyarteritis nodosa (cPAN) is a skin medium vessel neutrophilic arteritis with livedo, nodules, and ulcerations. Macular lymphocytic arteritis (MLA) is a small arteritis with erythematous or pigmented macules and typical histologic features (a lymphocytic infiltrate, concentric fibrin ring, no dis...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2015.09.010
更新日期:2015-12-01 00:00:00
abstract::The standard definition of itching (as "an unpleasant sensation that provokes the desire to scratch") takes no account of recent advances in knowledge about itch physiology. Always imprecise, this definition is also out-of-date. Its defects are discussed in this article, and some modifications are proposed. ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(98)70087-8
更新日期:1998-08-01 00:00:00
abstract::A recent study demonstrated that hirsute women with irregular menses had higher levels of serum androgens that hirsute women with regular menses. To investigate this finding, we measured total testosterone, biologically active testosterone, free testosterone, androstenedione, dehydroepiandrosterone, and dehydroepiandr...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(91)70064-9
更新日期:1991-03-01 00:00:00
abstract::Transillumination with a high-intensity fiberoptic light source is an effective means of diagnosing pneumothoraces and localizing arteries and veins for blood sampling. It has been used for these purposes in neonatal intensive care units since the 1970s. Thermal burns were reported in association with the technique in...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(99)70060-5
更新日期:1999-08-01 00:00:00
abstract::Five patients with the yellow nail syndrome triad are described; all five had yellow nails, primary lymphedema, and respiratory tract involvement. Four of the patients noted the onset of the syndrome after an episode of pneumonia. Four patients had a chronic productive cough, two had bronchiectasis, two had chronic si...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(84)70021-1
更新日期:1984-02-01 00:00:00
abstract::Cutaneous metastases present themselves in a variety of clinical patterns and tend to be manifested as indurated papules/nodules/tumors. Some of those clinical expressions are unique for certain types of metastases. This report describes an entirely different phenomenon of clinically incognito cutaneous metastases tha...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2006.05.011
更新日期:2006-12-01 00:00:00
abstract:BACKGROUND:Recurrences after Mohs micrographic surgery (MMS) have been associated in the past with aggressive tumor type, large tumor size, and location within certain anatomic subunits. These factors are beyond the control of the treating physician and not subject to quality improvement efforts. OBJECTIVE:We sought t...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2013.02.016
更新日期:2013-07-01 00:00:00
abstract::A 4-year-old girl with failure to thrive and intense pruritus associated with Alagille syndrome is described. The clinical features of this autosomal dominant disorder are reviewed. This case highlights the importance of recognizing the severe pruritus as a manifestation of the disease. ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2007.03.029
更新日期:2008-02-01 00:00:00
abstract:BACKGROUND:Several clinical studies have focused on the therapeutic effects of interferon gamma (IFN-gamma) in patients with severe atopic dermatitis (AD), although the dosage of recombinant IFN-gamma (rIFN-gamma), therapeutic schedule, and the degree of clinical improvement were different among studies. Although the e...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章
doi:
更新日期:2000-06-01 00:00:00
abstract:BACKGROUND:Nephrogenic systemic fibrosis is a fibrosing disorder associated with gadolinium (Gd)-based contrast agents dosed during renal insufficiency. OBJECTIVE:In two patients, Gd deposition in tissue affected by nephrogenic systemic fibrosis was quantified using inductively coupled plasma mass spectrometry. The pr...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2009.07.018
更新日期:2010-01-01 00:00:00
abstract::As a prerequisite to standardization of dermatophyte susceptibility testing, conditions that support optimal growth of different dermatophyte species must be established. Eighteen isolates of Trichophyton spp. (T rubrum, T mentagrophytes, T tonsurans) were grown in 4 different media: RPMI 1640 with L-glutamine, withou...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(99)70392-0
更新日期:1999-06-01 00:00:00
abstract::Cytodestructive or surgical therapy for patients with anogenital warts is frequently associated with recurrence. In February 1997, the US Food and Drug Administration approved imiquimod as a 5% cream for the treatment of anogenital warts. Activity of the drug results primarily from interferon alfa and other cytokine i...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1067/mjd.2002.126579
更新日期:2002-10-01 00:00:00
abstract::Skin cancer is less prevalent in people of color than in the white population. However, when skin cancer occurs in non-whites, it often presents at a more advanced stage, and thus the prognosis is worse compared with white patients. The increased morbidity and mortality associated with skin cancer in patients of color...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2013.11.038
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Serum levels of S100A8/A9 may correlate with disease activity in psoriasis. OBJECTIVE:We sought to elucidate the association of serum levels of S100A8/A9 heterodimers with the clinical subtypes of psoriasis and the major cell source. METHODS:Serum samples were collected from patients with psoriasis vulgari...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2010.02.049
更新日期:2011-05-01 00:00:00
abstract:BACKGROUND:Few studies have evaluated the relationship between hidradenitis suppurativa (HS) and type 2 diabetes mellitus (T2DM), and the existing data show conflicting results. OBJECTIVE:To determine the prevalence of T2DM among patients with HS and identify at-risk demographic subgroups. METHODS:Cross-sectional ana...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2018.01.014
更新日期:2018-07-01 00:00:00
abstract:UNLABELLED:Cutaneous flushing-a common presenting complaint to dermatologists, allergists, internists, and family practitioners-results from changes in cutaneous blood flow triggered by multiple conditions. Most cases are caused by very common, benign diseases, such as rosacea or climacterum, that are readily apparent ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2005.07.057
更新日期:2006-08-01 00:00:00
abstract::The efficacy of a sunscreen containing an investigational drug, butyl methoxydibenzoylmethane in combination with padimate O against the erythemogenic effect of ultraviolet A (UVA) radiation was evaluated in two double-blind studies involving subjects sensitized with topical 8-methoxypsoralen. UVA radiation was suppli...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章
doi:10.1016/s0190-9622(87)70195-9
更新日期:1987-08-01 00:00:00
abstract::Bowenoid papulosis is an uncommon genital dysplasia induced by human papillomavirus infection. Clinically, it usually resembles persistent warts, but histologically it may be suggestive of squamous cell carcinoma in situ. This unusual disorder and recent advances in our understanding of it are reviewed. ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/0190-9622(91)70039-5
更新日期:1991-02-01 00:00:00
abstract:BACKGROUND:Actinic keratosis (AK) is the earliest clinical manifestation of squamous cell carcinoma. Metastatic SCC causes the majority of the 1300 to 2300 deaths attributed to nonmelanoma skin cancer in the United States each year. Recent studies have shown that intralesional administration of interferon can be used s...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章
doi:10.1067/mjd.2002.123492
更新日期:2002-10-01 00:00:00
abstract:BACKGROUND:Embryofetal developmental toxicity associated with oral administration of vitamin A analogs has led to concern about risks from topical application. OBJECTIVE:This study was conducted to evaluate the potential developmental toxicity of tretinoin emollient cream when applied to the skin of pregnant New Zeala...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(97)70062-8
更新日期:1997-03-01 00:00:00
abstract::Acitretin, a metabolite of etretinate, was given to 38 patients for the treatment of psoriasis. During the first 8 weeks patients received either placebo, 10 mg, 25 mg, 50 mg, or 75 mg of acitretin daily in a double-blind manner. The dosages of 10 mg and 25 mg daily did not achieve any statistically significant improv...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章
doi:10.1016/s0190-9622(88)70086-9
更新日期:1988-04-01 00:00:00
abstract:BACKGROUND:Treatment of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) remains controversial. OBJECTIVE:We sought to evaluate the impact of cyclosporine on hospital mortality in patients with SJS/TEN. METHODS:All patients with SJS and TEN admitted to our center from 2011 to 2014 were treated unde...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2016.07.048
更新日期:2017-01-01 00:00:00
abstract::Two patients with a hypersensitivity vasculitis in association with propylthiouracil (PTU) administration are described. Although both patients presented with a cutaneous eruption, our first patient suffered severe systemic manifestations and the second patient's involvement was primarily limited to the skin. Patients...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/s0190-9622(99)70013-7
更新日期:1999-11-01 00:00:00