Propylthiouracil hypersensitivity: report of two patients with vasculitis and review of the literature.

abstract：:Chemexfoliation (chemical peeling) is being used to obtain both therapeutic (e.g., actinic keratoses) and cosmetic (e.g., removal of fine facial rhytides) benefits. Phenol, one of the most widely used agents for inducing cutaneous exfoliation, may induce cardiac arrhythmias and is toxic to the liver and kidneys. Trich...

journal_title：Journal of the American Academy of Dermatology

authors： Lober CW

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:For treatment of localized scleroderma numerous treatments, including ones with potentially hazardous side effects, are currently used with only limited success. OBJECTIVE:We attempted to determine the efficacy of low-dose UVA1 irradiation in patients with severe localized scleroderma. METHODS:Patients wer...

journal_title：Journal of the American Academy of Dermatology

authors： Kerscher M,Volkenandt M,Gruss C,Reuther T,von Kobyletzki G,Freitag M,Dirschka T,Altmeyer P

更新日期：1998-01-01 00:00:00

abstract：:We observed the course of development of porokeratosis stimulated by benzylhydrochlorothiazide (BHCTh) in normal-appearing skin of a patient with long-standing stable porokeratosis of Mibelli. A 72-year-old Japanese man had had porokeratosis of Mibelli for more than 50 years. During administration of BHCTh for 1 year ...

journal_title：Journal of the American Academy of Dermatology

authors： Inamoto N,Watanabe T,Nakamura K

更新日期：1984-08-01 00:00:00

abstract：BACKGROUND:The increasing use of biologics is accompanied by a risk of hepatitis B (HBV) and C virus (HCV) reactivation. OBJECTIVE:To determine the predictors of HBV and HCV reactivation in psoriasis patients receiving biologics. METHODS:This study screened 2060 psoriasis patients (3562 treatment episodes) who were t...

journal_title：Journal of the American Academy of Dermatology

authors： Chiu HY,Chiu YM,Chang Liao NF,Chi CC,Tsai TF,Hsieh CY,Hsieh TY,Lai KL,Chiu TM,Wu NL,Hui RC,Lee CN,Wang TS,Chen PH,Yang CC,Huang YH

更新日期：2019-12-07 00:00:00

abstract：:A 5-month-old boy with hypomelanosis of Ito was studied. Lesions presented as bizarre, hypopigmented whorls and streaks. Histologic studies showed that the hypopigmented areas contained normal melanocytes with decreased content of intracellular melanin. A review of the literature revealed the disease to be a discrete ...

journal_title：Journal of the American Academy of Dermatology

authors： Buzas JW,Sina B,Burnett JW

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:Molluscum contagiosum (MC) is a common and at times severely disfiguring cutaneous viral infection in patients with human immunodeficiency virus (HIV) infection. OBJECTIVE:The purpose of this study was to describe the clinical course of MC in patients with HIV infection and to examine the relation between p...

journal_title：Journal of the American Academy of Dermatology

authors： Schwartz JJ,Myskowski PL

更新日期：1992-10-01 00:00:00

abstract：:Two children who had classic maple syrup urine disease developed an eruptive dermatitis when plasma isoleucine levels, leucine levels, or both fell below normal during periods of protein restriction. The dermatitis was resistant to topical corticosteroid therapy. Rapid resolution occurred after treatment with isoleuci...

journal_title：Journal of the American Academy of Dermatology

authors： Koch SE,Packman S,Koch TK,Williams ML

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:There is limited data on zoster recurrence. OBJECTIVE:To examine in detail zoster recurrence in a population-based cohort. METHODS:Using data from a large cohort (The 45 and Up Study) with linked medical data (2004-2015), the incidence of first and recurrent zoster was examined using survival analyses meth...

journal_title：Journal of the American Academy of Dermatology

authors： Qian J,Macartney K,Heywood AE,Sheridan S,Liu B

更新日期：2020-07-02 00:00:00

abstract：:Cultured epidermal sheets were examined before and at various times after grafting on skin ulcer beds. Before grafting, the sheet consisted of four to five layers of keratinocytes with incomplete differentiation. Ten days after grafting, graft recipient sites showed compact hyperkeratosis, a normal-appearing epidermis...

journal_title：Journal of the American Academy of Dermatology

authors： Phillips TJ,Bhawan J,Leigh IM,Baum HJ,Gilchrest BA

更新日期：1990-08-01 00:00:00

abstract：:Palliative care has been shown to improve quality of life, symptom, and caregiver burden for a range of life-limiting diseases. Palliative care use among patients with severe dermatologic disease remain relatively unexplored, but the limited available data suggest significant unmet care needs and low rates of palliati...

journal_title：Journal of the American Academy of Dermatology

authors： Thompson LL,Chen ST,Lawton A,Charrow A

更新日期：2020-08-12 00:00:00

abstract：BACKGROUND:Telemedicine technology holds great promise for dermatologic health care delivery. However, the clinical outcomes of digital image consultations (teledermatology) must be compared with traditional clinic-based consultations. OBJECTIVE:Our purpose was to assess and compare the reliability and accuracy of der...

journal_title：Journal of the American Academy of Dermatology

authors： Whited JD,Hall RP,Simel DL,Foy ME,Stechuchak KM,Drugge RJ,Grichnik JM,Myers SA,Horner RD

更新日期：1999-11-01 00:00:00

abstract：OBJECTIVES:Our aim was to compare 20% with 10% to 5% incremental regimens in narrowband UVB phototherapy. STUDY PATIENTS:The study included patients with psoriasis (N = 191) with Fitzpatrick skin phototypes II and III. RESULTS:Occurrence of erythema as well as maximum and cumulative doses were higher with 20% escalat...

journal_title：Journal of the American Academy of Dermatology

authors： Boztepe G,Akinci H,Sahin S,Karaduman A,Evans SE,Erkin G,Atakan N,Akan T,Kölemen F

更新日期：2006-08-01 00:00:00

abstract：:Dermatologists frequently are consulted by a pregnant patient or a woman of childbearing age who desires acne therapy. Because there are no published studies in which women took acne medications throughout pregnancy, information about safety must be obtained indirectly from studies in which the agents were taken for a...

journal_title：Journal of the American Academy of Dermatology

authors： Rothman KF,Pochi PE

更新日期：1988-09-01 00:00:00

abstract：BACKGROUND:The efficacy of combination therapy with topical corticosteroids and tacrolimus in the treatment of atopic dermatitis remains to be established. OBJECTIVE:Our aim was to determine whether a regimen of sequential application of topical corticosteroids and topical tacrolimus is effective in the treatment of p...

journal_title：Journal of the American Academy of Dermatology

authors： Kubota Y,Yoneda K,Nakai K,Katsuura J,Moriue T,Matsuoka Y,Miyamoto I,Ohya Y

更新日期：2009-02-01 00:00:00

abstract：OBJECTIVE:We sought to assess the difference in lesion management between combined examination (naked-eye and dermoscopy) and conventional naked-eye examination in evaluations for melanoma; and to assess the impact on patient treatment of facilities for digital follow-up of diagnostically equivocal lesions. METHODS:We...

journal_title：Journal of the American Academy of Dermatology

authors： Carli P,de Giorgi V,Chiarugi A,Nardini P,Weinstock MA,Crocetti E,Stante M,Giannotti B

更新日期：2004-05-01 00:00:00

abstract：:Sweet's syndrome (SS) occurs most commonly in association with inflammatory or neoplastic disorders. Only rarely has it been associated with immunodeficiency disorders. We describe a child with a T-cell immunodeficiency who had a persistent neutrophilic dermatosis that was histologically and clinically consistent with...

journal_title：Journal of the American Academy of Dermatology

authors： Lipp KE,Shenefelt PD,Nelson RP Jr,Messina JL,Fenske NA

更新日期：1999-05-01 00:00:00

abstract：:The first reported case of phenytoin-induced generalized nodular cutaneous pseudolymphoma without symptoms of the phenytoin hypersensitivity syndrome is presented. Despite the malignant histologic appearance of the dermal infiltrate, T-cell receptor gene rearrangement studies did not demonstrate monoclonality. The cut...

journal_title：Journal of the American Academy of Dermatology

authors： Braddock SW,Harrington D,Vose J

更新日期：1992-08-01 00:00:00

abstract：:A 39-year-old white man who was taking quinidine developed a purpuric eruption in a photodistributed livedo reticularis-like pattern. This is the fourth reported case of a similar eruption in patients taking quinidine. Possible pathophysiologic mechanisms for nonthrombocytopenic drug-induced purpuras are discussed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Bruce S,Wolf JE Jr

更新日期：1985-02-01 00:00:00

abstract：:Recently, low-dose 5-fluorouracil/cisplatin induction concurrent with radiation (chemoradiation) has been reported to be effective for locally advanced squamous cell carcinoma of the otorhinolaryngologic and gynecologic regions. However, to date, this therapeutic option has not been evaluated for squamous cell carcino...

journal_title：Journal of the American Academy of Dermatology

authors： Fujisawa Y,Umebayashi Y,Ichikawa E,Kawachi Y,Otsuka F

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Calcipotriene and betamethasone dipropionate are topical treatments for psoriasis vulgaris. Their mode of action is different. Improved risk/benefit may result with concomitant use of the two compounds together. A new vehicle has been created with the objective of obtaining optimal stability of both calcipot...

journal_title：Journal of the American Academy of Dermatology

authors： Papp KA,Guenther L,Boyden B,Larsen FG,Harvima RJ,Guilhou JJ,Kaufmann R,Rogers S,van de Kerkhof PC,Hanssen LI,Tegner E,Burg G,Talbot D,Chu A

更新日期：2003-01-01 00:00:00

abstract：:This is the second reported case of minocycline-induced Sweet's syndrome (and the first such case to appear in the American literature). The syndrome developed in a 32-year-old man 10 days after minocycline therapy for acne was begun and resolved rapidly after discontinuation of the medication and start of oral predni...

journal_title：Journal of the American Academy of Dermatology

authors： Thibault MJ,Billick RC,Srolovitz H

更新日期：1992-11-01 00:00:00

abstract：:The term Richter syndrome (RS) describes the transformation of chronic lymphocytic leukemia into a high-grade lymphoma. RS occurs in 3% to 10% of chronic lymphocytic leukemia cases, and its onset is often characterized by the abrupt development of systemic symptoms (eg, fever in the absence of infection, night sweats,...

journal_title：Journal of the American Academy of Dermatology

authors： Yamazaki ML,Lum CA,Izumi AK

更新日期：2009-01-01 00:00:00

abstract：:We report two cases in which dermatophytic infection developed almost entirely within a radiation field mimicking an acute radiation effect. Radiotherapists and dermatologists should be aware of this possibility and be able to differentiate it from radiation dermatitis. Topical antifungal agents are the recommended tr...

journal_title：Journal of the American Academy of Dermatology

authors： Rosen T,Dupuy J,Maor M,Altman A

更新日期：1988-12-01 00:00:00

abstract：:We reviewed all cases of malignant melanoma in children younger than 17 years of age who were evaluated at Sainte Justine Hospital, a tertiary care pediatric center, between 1980 and 2002. The medical records and histologic features of all cases were reviewed. Thirteen cases were identified, 4 boys and 9 girls. Fifty-...

journal_title：Journal of the American Academy of Dermatology

authors： Jafarian F,Powell J,Kokta V,Champagne M,Hatami A,McCuaig C,Marcoux D,Savard P

更新日期：2005-11-01 00:00:00

abstract：BACKGROUND:A discrimination between benign and malignant melanocytic lesions is not always possible by conventional histology. OBJECTIVE:Our purpose was to determine the proliferative activity in various types of melanocytic neoplasms and to appraise its value as a diagnostic adjunct. METHODS:The growth fraction was ...

journal_title：Journal of the American Academy of Dermatology

authors： Rudolph P,Schubert C,Schubert B,Parwaresch R

更新日期：1997-08-01 00:00:00

abstract：:Malignant melanoma presenting as an inflammatory skin metastasis has been described but is an exceedingly rare phenomenon. We report an unusual case of a patient who developed right leg lesions that were initially thought to be infectious in origin. There was no resolution of these lesions with antibiotic therapy, and...

journal_title：Journal of the American Academy of Dermatology

authors： Cotton J,Armstrong DJ,Wedig R,Hood AF

更新日期：1998-11-01 00:00:00

abstract：:Anti-epiligrin cicatricial pemphigoid is an autoimmune subepithelial blistering disorder of mucous membranes and skin. By immunoblot analyses, sera of most patients with antiepiligrin cicatricial pemphigoid have been shown to react specifically with the alpha3 chain of laminin 5. We describe the first patient with ant...

journal_title：Journal of the American Academy of Dermatology

authors： Fujimoto W,Toi Y,Okazaki F,Lazarova Z,Yancey KB,Arata J

更新日期：1999-04-01 00:00:00

abstract：:A 49-year-old man presented with an acute onset of folliculitis on his right cheek. The folliculitis was unresponsive to antibiotics. A potassium hydroxide preparation of a scraping from the affected area revealed the presence of numerous Demodex mites. The patient was treated with topical crotamiton (Eurax) cream res...

journal_title：Journal of the American Academy of Dermatology

authors： Purcell SM,Hayes TJ,Dixon SL

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:Primary closure of surgical defects after excision of cutaneous malignancies has been traditionally accomplished with layered closure. OBJECTIVE:We sought to compare the cosmetic outcome of cheek defects repaired with layered closure versus buried sutures and adhesive strips. METHODS:In all, 38 patients un...

journal_title：Journal of the American Academy of Dermatology

authors： Plotner AN,Mailler-Savage E,Adams B,Gloster HM Jr

更新日期：2011-06-01 00:00:00

abstract：BACKGROUND:The lack of recommendations regarding dosing and administration, an undetermined risk of hypothalamic-pituitary-adrenal axis alteration, and the unknown effectiveness of intramuscular (IM) corticosteroid injection to treat dermatologic disease may be deterrents to use. OBJECTIVE:We sought to evaluate presen...

journal_title：Journal of the American Academy of Dermatology

authors： Reddy S,Ananthakrishnan S,Garg A

更新日期：2013-08-01 00:00:00