Proliferation marker Ki-S5 as a diagnostic tool in melanocytic lesions.

abstract：BACKGROUND:Melanoma is one of the deadliest forms of skin cancer, having a high metastatic potential and afflicting all age groups. The need for successful preventative measures is particularly urgent as metastatic melanoma is largely incurable. The beneficial role of nutrition and other natural compounds in the preven...

journal_title：Journal of the American Academy of Dermatology

authors： Tong LX,Young LC

更新日期：2014-07-01 00:00:00

abstract：:The association of palmoplantar hyperkeratosis and mycosis fungoides (MF) has been described less frequently in the dermatologic literature. We present a patient with MF who developed hyperkeratosis of the palms and soles. Histologic examination of a specimen from the left palm showed microscopic changes of MF. ...

journal_title：Journal of the American Academy of Dermatology

authors： Aram H,Zeidenbaum M

更新日期：1985-11-01 00:00:00

abstract：:Blistering of light-exposed skin, pink-stained fluorescing diapers, and fluorescing peripheral erythrocytes led to diagnosis of congenital porphyria in an infant born to consanguineous parents. Although massive coproporphyrinuria and coproporphyrinemia initially suggested a coproporphyrinogen oxidase deficiency disord...

journal_title：Journal of the American Academy of Dermatology

authors： Huang JL,Zaider E,Roth P,Garcia O,Pollack S,Poh-Fitzpatrick MB

更新日期：1996-05-01 00:00:00

abstract：BACKGROUND:Methyldibromoglutaronitrile (MDGN) is a component of Euxyl K400, a preservative used in many skin care products in Europe. MDGN has been used in skin care products in the United States for the last 5 years. Contact allergy from MDGN has been reported from Europe. OBJECTIVE:The purpose of this study was to d...

journal_title：Journal of the American Academy of Dermatology

authors： Jackson JM,Fowler JF

更新日期：1998-06-01 00:00:00

abstract：:Two patients with a hypersensitivity vasculitis in association with propylthiouracil (PTU) administration are described. Although both patients presented with a cutaneous eruption, our first patient suffered severe systemic manifestations and the second patient's involvement was primarily limited to the skin. Patients...

journal_title：Journal of the American Academy of Dermatology

authors： Chastain MA,Russo GG,Boh EE,Chastain JB,Falabella A,Millikan LE

更新日期：1999-11-01 00:00:00

abstract：BACKGROUND:HLA-DR1 is associated with the development of multiple basal cell carcinomas (BCC). However, the association is weak. OBJECTIVE:The purpose of our study was to determine whether HLA-DR1 is a marker for susceptibility to the development of many BCCs during a lifetime. METHODS:Persons with multiple BCCs were...

journal_title：Journal of the American Academy of Dermatology

authors： Czarnecki D,Lewis A,Nicholson I,Tait B,Nash C

更新日期：1992-05-01 00:00:00

abstract：:Pyoderma gangrenosum may occur in unusual sites and not be readily recognized. Delays in diagnosis and appropriate treatment may result in extensive ulcerations and scarring. We present two patients with pyoderma gangrenosum involving the breasts after breast operation. Delays in diagnosis resulted in extensive ulcera...

journal_title：Journal of the American Academy of Dermatology

authors： Davis MD,Alexander JL,Prawer SE

更新日期：2006-08-01 00:00:00

abstract：:Blood eosinophilia is a common feature of eosinophilic fasciitis and is variably reported in systemic sclerosis and localized scleroderma. Since these diseases share cutaneous fibrosis as the final outcome and have other clinical and pathologic features that are difficult to differentiate, the presence of blood eosino...

journal_title：Journal of the American Academy of Dermatology

authors： Falanga V,Medsger TA Jr

更新日期：1987-10-01 00:00:00

abstract：:Onycholysis (ONY) of the fingernails is a common disorder that is diagnosed with ease but often managed with great difficulty. The full spectrum of causes is broad and not always readily apparent. In this review, an approach to the evaluation and management of ONY is offered. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kechijian P

更新日期：1985-03-01 00:00:00

abstract：:A 38-year-old woman came for treatment of multiple clear vesicles and hemorrhagic papules on the posterior aspect of the right shoulder and the right axillary vault of 5 years' duration. These lesions would spontaneously manifest as clear or blood-filled vesicles (or both) and appear to be exacerbated by physical cont...

journal_title：Journal of the American Academy of Dermatology

authors： Bikowski JB,Dumont AM

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:Appropriate primary end points in randomized controlled trials (RCTs) improve the quality of the measurement and enable comparison of the findings with those of other trials. OBJECTIVE:To assess the quality of reporting primary end points in RCTs recently published in dermatology journals. METHODS:We ident...

journal_title：Journal of the American Academy of Dermatology

authors： Kim DY,Oh S,Yoon HS

更新日期：2020-04-22 00:00:00

abstract：:During the past two decades, systemic μ-opioid receptor antagonists (MORA) have been used in the treatment of various forms of chronic pruritus. In a number of case reports, case series, and controlled trials, treatment with MORA has demonstrated considerable antipruritic effects. In double-blind controlled studies, s...

journal_title：Journal of the American Academy of Dermatology

authors： Phan NQ,Bernhard JD,Luger TA,Ständer S

更新日期：2010-10-01 00:00:00

abstract：:Sunscreen preparations can reduce the erythemogenic ( sunburning ) effects of solar ultraviolet radiation (UVR). Less is known about the ability of sunscreens to protect against other forms of UVR-induced damage. This study was designed to yield data on epidermal cell damage at UVR doses sufficient to provoke vascular...

journal_title：Journal of the American Academy of Dermatology

authors： Sambuco CP,Forbes PD,Davies RE,Urbach F

更新日期：1984-05-01 00:00:00

abstract：:Blue-brown macules of the face occurring on both sides of the forehead, temple, eyelids, malar area, alae of the nose, and root of the nose are often observed in middle-aged Japanese women. These lesions histologically are a form of dermal melanocytosis as shown by electron microscopic examination. They differ clinica...

journal_title：Journal of the American Academy of Dermatology

authors： Hori Y,Kawashima M,Oohara K,Kukita A

更新日期：1984-06-01 00:00:00

abstract：:This review of epidemiologic, clinical, and psychosocial/psychobehavioral data related to genital herpes simplex virus infection details the increasing incidence of herpes simplex virus infection in the United States and summarizes the data regarding the safety and efficacy of chronic and acute antiviral therapy with ...

journal_title：Journal of the American Academy of Dermatology

authors： Conant MA,Berger TG,Coates TJ,Longo DJ,Robinson JK,Drake LA

更新日期：1996-10-01 00:00:00

abstract：:Hyperpigmentation, pulmonary infiltration, and erythema nodosum occurred in a patient receiving long-term minocycline therapy. Bronchoalveolar lavage revealed both a neutrophilic and an eosinophilic alveolitis. The pulmonary and systemic symptoms promptly resolved after discontinuation of minocycline. ...

journal_title：Journal of the American Academy of Dermatology

authors： Bridges AJ,Graziano FM,Calhoun W,Reizner GT

更新日期：1990-05-01 00:00:00

abstract：:We report a case of a neonate with a congenital tumor on the left palm. The patient had a grapefruit-sized tumor and coagulopathy at birth and was presumed to have a hemangioendothelioma with associated Kasabach-Merritt phenomenon. When the tumor failed to respond to systemic steroids, a biopsy specimen was taken, rev...

journal_title：Journal of the American Academy of Dermatology

authors： Asgari M,Rubin BP,Hornung RL

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Segmental vitiligo (SV) is characterized by a unilateral and localized distribution, early onset, and stable disease after rapid progression. And SV is often associated with poor response to various treatment modalities. OBJECTIVE:We sought to evaluate the effectiveness of combination therapy with 308-nm ex...

journal_title：Journal of the American Academy of Dermatology

authors： Bae JM,Yoo HJ,Kim H,Lee JH,Kim GM

更新日期：2015-07-01 00:00:00

abstract：BACKGROUND:Even with the addition of dermoscopy, a significant morphologic overlap exists between irritated seborrheic keratosis (ISK) and squamous cell carcinoma (SCC). OBJECTIVE:The aim of this study was to investigate the dermoscopic criteria that could serve as potent predictors for the differential diagnosis betw...

journal_title：Journal of the American Academy of Dermatology

authors： Papageorgiou C,Spyridis I,Manoli SM,Busila I,Nasturica IE,Lallas K,Panagopoulou A,Papadimitriou I,Sideris N,Gentsidi T,Gonzalez-Cuevas R,Ilieva A,Ioannides D,Apalla Z,Lallas A

更新日期：2020-02-14 00:00:00

abstract：:Lymphomatoid papulosis is a chronic disease of cutaneous lymphoid infiltration characterized clinically by involuting and recurring papules, plaques, and nodules. The intriguing combination of a usually benign clinical course, a cytologically malignant lymphoid infiltrate on histologic examination, and a clear, but sp...

journal_title：Journal of the American Academy of Dermatology

authors： Karp DL,Horn TD

更新日期：1994-03-01 00:00:00

abstract：BACKGROUND:Confetti-like depigmentation was noted in patients reporting recent worsening of vitiligo. OBJECTIVE:We sought to determine if confetti-like depigmentation is a marker of rapidly progressing vitiligo. METHODS:Review of patient records and images of patients from a vitiligo registry resulted in 7 patients w...

journal_title：Journal of the American Academy of Dermatology

authors： Sosa JJ,Currimbhoy SD,Ukoha U,Sirignano S,O'Leary R,Vandergriff T,Hynan LS,Pandya AG

更新日期：2015-08-01 00:00:00

abstract：:The early experiments of Marion B. Sulzberger suggested that the skin played a vital role in the generation of allergic contact dermatitis and other delayed type hypersensitivity reactions. This lecture is presented in the historical context of Dr. Sulzberger's lifework and interest in mechanisms involved in delayed t...

journal_title：Journal of the American Academy of Dermatology

authors： Katz SI

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Increases in the incidence of malignant melanoma have been among the largest of all cancers in the United States. OBJECTIVE:We report updated trends in melanoma rates among the US white population. METHODS:Incidence and mortality rates were calculated for 1973 to 1994. Trends were examined with stratificat...

journal_title：Journal of the American Academy of Dermatology

authors： Hall HI,Miller DR,Rogers JD,Bewerse B

更新日期：1999-01-01 00:00:00

abstract：:Three patients are described who had a distinctive clinical and histologic presentation of dermal elastosis. Sunlight apparently played little role in the development of this elastotic change. To the best of our knowledge, this is the first report of this form of elastosis. ...

journal_title：Journal of the American Academy of Dermatology

authors： Burket JM,Zelickson AS,Padilla RS

更新日期：1989-04-01 00:00:00

abstract：:Allergic contact dermatitis (ACD), a delayed hypersensitivity skin reaction to environmental allergens, has a prevalence that is similar in children and adults. However, diagnostic testing for ACD in pediatric populations accounts for less than one tenth of all patch tests. The relative infrequency of pediatric patch ...

journal_title：Journal of the American Academy of Dermatology

authors： Neale H,Garza-Mayers AC,Tam I,Yu J

更新日期：2021-02-01 00:00:00

abstract：:Keratosis follicularis spinulosa decalvans is a rare, X-linked disorder affecting both the skin and eyes. There are few reports about this entity. The aim of this report is to describe 2 brothers with progressive scarring alopecia of the scalp, hypotrichosis with follicular prominence of the eyelashes, and extensive k...

journal_title：Journal of the American Academy of Dermatology

authors： Alfadley A,Al Hawsawi K,Hainau B,Al Aboud K

更新日期：2002-11-01 00:00:00

abstract：:Transillumination with a high-intensity fiberoptic light source is an effective means of diagnosing pneumothoraces and localizing arteries and veins for blood sampling. It has been used for these purposes in neonatal intensive care units since the 1970s. Thermal burns were reported in association with the technique in...

journal_title：Journal of the American Academy of Dermatology

authors： Sajben FP,Gibbs NF,Friedlander SF

更新日期：1999-08-01 00:00:00

abstract：:Capecitabine, an oral fluoropyrimidine and 5-fluorouracil (FU) prodrug recently approved for the treatment of metastatic colon and breast cancer, is currently under investigation in patients with gastric cancer. It has the advantage of oral administration, and good tolerability with its activity being comparable with ...

journal_title：Journal of the American Academy of Dermatology

authors： Weger W,Kränke B,Gerger A,Salmhofer W,Aberer E

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Highly variable results of topical diphenylcyclopropenone (DPCP) in the treatment of alopecia areata have been reported so far. OBJECTIVE:The purposes of our study were to evaluate the efficacy and tolerability of DPCP in the treatment of chronic, extensive alopecia areata and to assess the long-term overal...

journal_title：Journal of the American Academy of Dermatology

authors： Cotellessa C,Peris K,Caracciolo E,Mordenti C,Chimenti S

更新日期：2001-01-01 00:00:00

abstract：:"Poikiloderma" is a morphologic and descriptive term referring to a combination of cutaneous atrophy, telangiectasia, and varied macular pigmentary changes that result in a mottled skin appearance. Its etiology includes both congenital and acquired causes. Many studies have reported different causes of acquired poikil...

journal_title：Journal of the American Academy of Dermatology

authors： Nofal A,Salah E

更新日期：2013-09-01 00:00:00