Linear focal elastosis (elastotic striae).

abstract：:Skin specimens from five mummies were examined histologically. The specimens ranged in age from 2,000 to 3,200 years. Material from two mummies had carbonized and showed only amorphous debris. The histology of the three remaining skin fragments retained surprising histologic architectural detail. One specimen obtained...

journal_title：Journal of the American Academy of Dermatology

authors： Chapel TA,Mehregan AH,Reyman TA

更新日期：1981-01-01 00:00:00

abstract：:Acrocyanosis is an uncommon condition characterized by symmetric coolness and violaceous discoloration of the hands and feet. The nose, ears, lips, and nipples are also often affected. The disease is temperature dependent and generally worsens with cold exposure. Acrocyanosis is often secondary to a variety of underly...

journal_title：Journal of the American Academy of Dermatology

authors： Nousari HC,Kimyai-Asadi A,Anhalt GJ

更新日期：2001-12-01 00:00:00

abstract：BACKGROUND:The co-existence of hidradenitis suppurativa (HS) and atopic dermatitis (AD) had been reported but was not investigated in controlled studies. OBJECTIVE:To evaluate the bidirectional association between HS and AD. METHODS:A population-based retrospective cohort study was conducted to compare incidence rate...

journal_title：Journal of the American Academy of Dermatology

authors： Sherman S,Kridin K,Bitan DT,Leshem YA,Hodak E,Cohen AD

更新日期：2020-12-27 00:00:00

abstract：BACKGROUND:Hidradenitis suppurativa (HS) is often associated with inflammatory bowel disease (IBD; Crohn's disease or ulcerative colitis). However, the prevalence of IBD in HS patients is unknown. OBJECTIVE:To determine the prevalence of IBD in HS patients, and determine if patients with HS and IBD have a distinct HS ...

journal_title：Journal of the American Academy of Dermatology

authors： Deckers IE,Benhadou F,Koldijk MJ,Del Marmol V,Horváth B,Boer J,van der Zee HH,Prens EP

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Dermatomyositis (DM) is a multisystem autoimmune disease, in which serologic evidence of immune responses to disease-specific antigenic targets is found in approximately 50% to 70% of patients. Recently, melanoma differentiation-associated gene 5 (MDA5) has been identified as a DM-specific autoantigen that a...

journal_title：Journal of the American Academy of Dermatology

authors： Fiorentino D,Chung L,Zwerner J,Rosen A,Casciola-Rosen L

更新日期：2011-07-01 00:00:00

abstract：:Two patients with atypical histologic and immunohistochemical findings in nevi after cryotherapy are reported. Patient 1, a 32-year-old white woman, presented to our cancer center with two changing moles that had been treated with liquid nitrogen therapy by her primary care provider. After cryotherapy, these two lesio...

journal_title：Journal of the American Academy of Dermatology

authors： Adeniran AJ,Prieto VG,Chon S,Duvic M,Diwan AH

更新日期：2009-08-01 00:00:00

abstract：:Multiple modalities exist for the treatment of keratoacanthoma. Excisional surgery is currently the treatment of choice for the majority of keratoacanthomas. This can result in functional and cosmetic defects when large or strategically located lesions are treated. An effective nonsurgical treatment would be desirable...

journal_title：Journal of the American Academy of Dermatology

authors： Melton JL,Nelson BR,Stough DB,Brown MD,Swanson NA,Johnson TM

更新日期：1991-12-01 00:00:00

abstract：:The term Richter syndrome (RS) describes the transformation of chronic lymphocytic leukemia into a high-grade lymphoma. RS occurs in 3% to 10% of chronic lymphocytic leukemia cases, and its onset is often characterized by the abrupt development of systemic symptoms (eg, fever in the absence of infection, night sweats,...

journal_title：Journal of the American Academy of Dermatology

authors： Yamazaki ML,Lum CA,Izumi AK

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Little is known about the utilization of medical services for psoriasis. OBJECTIVE:Our purpose was to quantify the medical resources utilized in the United States for the treatment of psoriasis. METHODS:By utilizing data tapes from the National Center of Health Statistics we estimated the number of outpati...

journal_title：Journal of the American Academy of Dermatology

authors： Stem RS

更新日期：1996-10-01 00:00:00

abstract：:Twenty-five years ago the use of pyridoxine was described for the treatment of photosensitivity eruptions. We report two cases of erythropoietic protoporphyria, which were only moderately responsive to beta-carotene and sunscreens, whereas the use of pyridoxine has been associated with a marked reduction in photosensi...

journal_title：Journal of the American Academy of Dermatology

authors： Ross JB,Moss MA

更新日期：1990-02-01 00:00:00

abstract：:There has been a resurgence of syphilis in the past decade. Uncommonly, diffuse hair loss, termed essential alopecia, is the only sign of syphilitic infection. We describe two patients with syphilis in whom the first sign of disease was alopecia and discuss the clinical and histopathologic findings of essential syphil...

journal_title：Journal of the American Academy of Dermatology

authors： Cuozzo DW,Benson PM,Sperling LC,Skelton HG 3rd

更新日期：1995-05-01 00:00:00

abstract：:As discussed in the first article in this continuing medical education series, angioinvasive fungal infections pose a significant risk to immunocompromised and immunocompetent patients alike, with a potential for severe morbidity and high mortality. The first article in this series focused on the epidemiology and clin...

journal_title：Journal of the American Academy of Dermatology

authors： Berger AP,Ford BA,Brown-Joel Z,Shields BE,Rosenbach M,Wanat KA

更新日期：2019-04-01 00:00:00

abstract：BACKGROUND:Scleredema adultorum (SA) is a rare connective tissue disorder for which no treatment has proven to be effective. OBJECTIVE:Our purpose was to determine the effect of bath-PUVA therapy on SA. METHODS:Three patients were treated. Clinical evaluation of skin induration and thickness as well as ultrasonograph...

journal_title：Journal of the American Academy of Dermatology

authors： Hager CM,Sobhi HA,Hunzelmann N,Wickenhauser C,Scharenberg R,Krieg T,Scharffetter-Kochanek K

更新日期：1998-02-01 00:00:00

abstract：:Primary cutaneous T-cell lymphomas are non-Hodgkin's lymphomas with varied clinical presentation and prognosis. The most common subtypes of cutaneous T-cell lymphomas are the epidermotropic variants mycosis fungoides and Sézary syndrome. Treatment of mycosis fungoides has encompassed a variety of modalities including ...

journal_title：Journal of the American Academy of Dermatology

authors： Querfeld C,Rosen ST,Guitart J,Rademaker A,Fung BB,Posten W,Kuzel TM

更新日期：2004-07-01 00:00:00

abstract：BACKGROUND:Cutaneous polyarteritis nodosa (cPAN) is a skin medium vessel neutrophilic arteritis with livedo, nodules, and ulcerations. Macular lymphocytic arteritis (MLA) is a small arteritis with erythematous or pigmented macules and typical histologic features (a lymphocytic infiltrate, concentric fibrin ring, no dis...

journal_title：Journal of the American Academy of Dermatology

authors： Buffiere-Morgado A,Battistella M,Vignon-Pennamen MD,de Masson A,Rybojad M,Petit A,Cordoliani F,Begon E,Flageul B,Mahr A,Bagot M,Bouaziz JD

更新日期：2015-12-01 00:00:00

abstract：:In recognition of continuing increases in the incidence of skin cancer, including malignant melanoma, the American Academy of Dermatology has encouraged dermatologic communities nationwide to offer free skin cancer screening to the public. Memorial Sloan-Kettering Cancer Center took part in one such effort last spring...

journal_title：Journal of the American Academy of Dermatology

authors： Girasek DC

更新日期：1986-08-01 00:00:00

abstract：:Dermatomyositis (DM) is an idiopathic inflammatory myopathy. The mainstay of treatment for DM is oral corticosteroids. However, the dose and length of treatment is debated. Adding to the confusion, there have been no randomized controlled studies comparing the use of various corticosteroid doses and taper rates, and n...

journal_title：Journal of the American Academy of Dermatology

authors： Iorizzo LJ 3rd,Jorizzo JL

更新日期：2008-07-01 00:00:00

abstract：BACKGROUND:Glomangiomas are benign tumors arising from neuromyoarterial cells surrounding cutaneous arteriovenous anastomoses that serve as temperature regulators. They exist as solitary or multiple types, occurring sporadically or in a familial pattern, the latter of which is rare. OBJECTIVE:We describe a 4-generatio...

journal_title：Journal of the American Academy of Dermatology

authors： Blume-Peytavi U,Adler YD,Geilen CC,Ahmad W,Christiano A,Goerdt S,Orfanos CE

更新日期：2000-04-01 00:00:00

abstract：:We report an unusual case of congenital melanocytic nevus presenting in a 19-year-old African woman as widespread papules and variably sized nodules and tumors affecting the entire body, including the palms, soles, and oral mucous membrane. Histopathologic examination of 3 representative skin lesions showed mainly der...

journal_title：Journal of the American Academy of Dermatology

authors： Rose C,Kaddu S,El-Sherif TF,Kerl H

更新日期：2003-10-01 00:00:00

abstract：:A 24-year-old woman with autoimmune thrombocytopenia and hypothyroidism had an inflammatory bullous eruption in the mouth, face, and trunk that left no milia or scars after healing. Histologic examination revealed a subepidermal bulla and a neutrophil infiltration. Direct immunofluorescence examination showed depositi...

journal_title：Journal of the American Academy of Dermatology

authors： Taniuchi K,Inaoki M,Nishimura Y,Mori T,Takehara K

更新日期：1997-02-01 00:00:00

abstract：:Atenolol is a beta-blocker commonly used for treating hypertension. It can induce various kinds of adverse side effects, including psoriasiform skin eruptions, skin necrosis, vasculitis, and (rarely) drug-induced connective tissue disease. We encountered a patient receiving atenolol for his hypertension for 3 years wh...

journal_title：Journal of the American Academy of Dermatology

authors： McGuiness M,Frye RA,Deng JS

更新日期：1997-08-01 00:00:00

abstract：:UVB irradiation is known to produce DNA damage at mutation hotspots in the p53 tumor suppressor gene, leading to the development of skin cancers. Mutations in the PTCH tumor suppressor gene, which is known to be responsible for the development of nevoid basal cell carcinoma syndrome, have also been identified in spora...

journal_title：Journal of the American Academy of Dermatology

authors： Ratner D,Peacocke M,Zhang H,Ping XL,Tsou HC

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Confirmation of mild bites caused by Loxosceles reclusa with swab testing has not been previously documented, to our knowledge. METHODS:We report a case using an enzyme-linked immunosorbent assay (ELISA) test. RESULTS:A lesion lacking necrosis or other specific signs of loxoscelism was confirmed by identif...

journal_title：Journal of the American Academy of Dermatology

authors： Stoecker WV,Green JA,Gomez HF

更新日期：2006-11-01 00:00:00

abstract：:Four patients are described with stony-hard induration of the skin and deeper tissues, most pronounced on the buttocks, thighs, and legs, and with limitation of joint mobility and contractures of the lower limbs. Two patients were siblings and one was the product of a consanguineous marriage. The disorder appears to b...

journal_title：Journal of the American Academy of Dermatology

authors： Jablonska S,Schubert H,Kikuchi I

更新日期：1989-11-01 00:00:00

abstract：:Mastocytosis is a disease in which the mast cell population is increased in various tissues. Although the mechanism for the increased density of mast cells is not understood, recent research into mast cell structure and function has improved our understanding of the symptomatology and prompted newer and better approac...

journal_title：Journal of the American Academy of Dermatology

authors： DiBacco RS,DeLeo VA

更新日期：1982-12-01 00:00:00

abstract：:Hydrogen peroxide (H2O2) is an endogenous reactive oxygen species that contributes to oxidative stress directly as a molecular oxidant and indirectly through free radical generation. Topically applied 1% to 45% H2O2 can be used for a range of clinical purposes, which will be reviewed here in addition to its safety. In...

journal_title：Journal of the American Academy of Dermatology

authors： Murphy EC,Friedman AJ

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:Recurrences after Mohs micrographic surgery (MMS) have been associated in the past with aggressive tumor type, large tumor size, and location within certain anatomic subunits. These factors are beyond the control of the treating physician and not subject to quality improvement efforts. OBJECTIVE:We sought t...

journal_title：Journal of the American Academy of Dermatology

authors： Campbell T,Armstrong AW,Schupp CW,Barr K,Eisen DB

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Onychomycosis is observed less frequently in children than adults. Until recently management of onychomycosis in children included topical formulations, oral griseofulvin, and in some cases deferral of treatment. OBJECTIVE:We attempted to determine the prevalence of onychomycosis in North American children ...

journal_title：Journal of the American Academy of Dermatology

authors： Gupta AK,Sibbald RG,Lynde CW,Hull PR,Prussick R,Shear NH,De Doncker P,Daniel CR 3rd,Elewski BE

更新日期：1997-03-01 00:00:00

abstract：:Keratosis lichenoides chronica is a rare dermatosis of unknown etiology with a wide variety of cutaneous manifestations. We present a 47-year-old male with a history of progressive and recalcitrant hyperkeratotic and warty plaques, mimicking verrucous secondary syphilis both clinically and microscopically. We review t...

journal_title：Journal of the American Academy of Dermatology

authors： Jayaraman AG,Pomerantz D,Robinson-Bostom L

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Noninvoluting congenital hemangioma (NICH) is a distinct vascular tumor of infancy. OBJECTIVE:We describe the clinical characteristics, histopathology, imaging, and natural history of NICH and compare our findings with previous reports. METHODS:We conducted a retrospective review of charts and photographic...

journal_title：Journal of the American Academy of Dermatology

authors： Lee PW,Frieden IJ,Streicher JL,McCalmont T,Haggstrom AN

更新日期：2014-05-01 00:00:00