Hidradenitis Suppurativa and Atopic Dermatitis: A Two-Way Association.

Abstract:

BACKGROUND:The co-existence of hidradenitis suppurativa (HS) and atopic dermatitis (AD) had been reported but was not investigated in controlled studies. OBJECTIVE:To evaluate the bidirectional association between HS and AD. METHODS:A population-based retrospective cohort study was conducted to compare incidence rate of AD among HS patients (n=6,779) and age-, gender- and ethnicity-matched control subjects (n=33,260). Adjusted hazard ratios (HRs) and adjusted odds ratios (ORs) were estimated. RESULTS:The incidence of AD was 2.51 (95% CI, 2.07-3.02) and 1.24 (95%CI, 1.10-1.40) per 1,000 person-years among patients with HS and controls, respectively. Patients with HS were twice as likely to develop AD as controls (HR, 2.06; 95%CI, 1.64-2.58). Furthermore, the prevalence of preexisting AD was higher in patients with HS than in control subjects (2.5% vs. 1.8%, respectively; P<0.001). A history of AD was associated with a 40% increase in the odds of HS (OR, 1.41; 95%CI, 1.19-1.67). Relative to patients with isolated HS, those with a dual diagnosis of HS and AD were younger, had a female predominance, lower prevalence of smoking, and lower body mass index (BMI). LIMITATIONS:Retrospective data collection CONCLUSIONS: A bidirectional association between HS and AD was observed. Dermatologists should be aware of this association.

journal_name

J Am Acad Dermatol

authors

Sherman S,Kridin K,Bitan DT,Leshem YA,Hodak E,Cohen AD

doi

10.1016/j.jaad.2020.12.051

subject

Has Abstract

pub_date

2020-12-27 00:00:00

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(20)33250-3

pub_type

杂志文章
  • Primary hyperoxaluria: report of a patient with livedo reticularis and digital infarcts.

    abstract::Primary hyperoxaluria encompasses 3 rare genetic disorders of glyoxylate metabolism characterized by excessive urinary excretion of oxalic acid, resulting in oxalosis. Patients typically have recurrent calcium oxalate nephrolithiasis and nephrocalcinosis, leading to chronic renal failure and death from uremia. Oxalate...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1067/mjd.2002.105475

    authors: Marconi V,Mofid MZ,McCall C,Eckman I,Nousari HC

    更新日期:2002-02-01 00:00:00

  • Severe and refractory solar urticaria treated with intravenous immunoglobulins: a phase II multicenter study.

    abstract:BACKGROUND:Retrospective data have suggested the effectiveness of intravenous immunoglobulins (IVIG) for solar urticaria (SU). OBJECTIVE:We sought to prospectively assess the efficacy of IVIG for SU. METHODS:We conducted a multicentric phase II study to test the efficacy of a single course of IVIG (2 g/kg) in patient...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jaad.2014.07.023

    authors: Aubin F,Porcher R,Jeanmougin M,Léonard F,Bedane C,Moreau A,Schmutz JL,Marguery MC,Adamski H,Viguier M,Société Française de Photodermatologie.

    更新日期:2014-11-01 00:00:00

  • Lupus erythematosus.

    abstract::Lupus erythematosus (LE) is a multisystem disease. Genetic predisposition, altered immunity, hormones, drugs, viruses, and ultraviolet light all may play a role in etiology. A wide range of cutaneous lesions occur, and variants such as subacute cutaneous LE, complement-deficient LE, and neonatal LE have recently been ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(81)70016-1

    authors: Tuffanelli DL

    更新日期:1981-02-01 00:00:00

  • Punch biopsy of melanoma.

    abstract::A 46-year-old albino woman is described with a melanoma on the leg from which a punch biopsy specimen was inadvertently taken. In the reexcision specimen, two biopsy wounds were recognized that were filled with tumor. The initial level III lesion had to be subsequently reported as a deep level IV amelanotic melanoma w...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(85)70238-1

    authors: van der Esch EP,Rampen FH

    更新日期:1985-11-01 00:00:00

  • Self-healing papular mucinosis in an adult.

    abstract::Papular mucinosis is a rare, idiopathic cutaneous mucinosis that is typically chronic and progressively severe. We present a case of a 59-year-old woman with a 6-month history of a dramatic papular eruption on her face and neck, with no associated internal organ involvement. A biopsy specimen demonstrated increased de...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(03)00790-4

    authors: Sperber BR,Allee J,James WD

    更新日期:2004-01-01 00:00:00

  • Epidermal effects of retinoids: supramolecular observations and clinical implications.

    abstract::Retinoids, synthetic vitamin A analogs, stimulate mucous metaplasia and gap-junction proliferation in embryonic and neoplastic epidermis. Such effects demonstrate that vitamin A has potent effects on epidermal differentiation. Oddly, however, retinoid action in normal postnatal tissues, where these drugs are used clin...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(86)70236-3

    authors: Elias PM

    更新日期:1986-10-01 00:00:00

  • What have we learned in dermatology from the biologic therapies?

    abstract::Recent advances in our basic understanding of immunology, specifically the roles of various cell types involved in immune response and the action of cytokines they produce, has radically changed our understanding of the origin of inflammatory dermatoses, and other autoimmune diseases. Broadened comprehension of the im...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 信件,评审

    doi:10.1016/j.jaad.2005.10.059

    authors: Nickoloff BJ,Stevens SR

    更新日期:2006-03-01 00:00:00

  • Follicular accentuation of leukocytoclastic vasculitis in an HIV-seropositive man. Report of a case and review of the literature.

    abstract::Palpable purpura in a follicular localization developed in association with acute epididymitis in a white man who was seropositive for the human immunodeficiency virus (HIV). Biopsy specimens revealed a leukocytoclastic vasculitis with follicular accentuation. With antibiotic therapy the vasculitis resolved, but it re...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/0190-9622(91)70143-p

    authors: Weimer CE Jr,Sahn EE

    更新日期:1991-05-01 00:00:00

  • Cutaneous malignant melanoma in the Swedish organ transplantation cohort: A study of clinicopathological characteristics and mortality.

    abstract:BACKGROUND:Risk of cutaneous melanoma is increased among organ transplant recipients (OTRs) but outcome has rarely been evaluated. OBJECTIVE:We sought to assess melanoma characteristics and prognosis among OTRs versus the general population. METHODS:Using Swedish health care registers, we identified melanomas in OTRs...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2015.03.045

    authors: Krynitz B,Rozell BL,Lyth J,Smedby KE,Lindelöf B

    更新日期:2015-07-01 00:00:00

  • Chronic pain management in dermatology: a guide to assessment and nonopioid pharmacotherapy.

    abstract::Pain is a central component of illness and suffering, yet unfortunately it is frequently undertreated. In dermatology, many acute and chronic conditions are characterized by pain that may require therapeutic intervention in addition to medical treatment aimed at treating the primary disease. To date, however, there ar...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2014.11.039

    authors: Enamandram M,Rathmell JP,Kimball AB

    更新日期:2015-10-01 00:00:00

  • Chronic pruritic eruption in patients with acquired immunodeficiency syndrome associated with increased antibody titers to mosquito salivary gland antigens.

    abstract::Five of seven patients with acquired immunodeficiency syndrome (AIDS) who had pruritus and a chronic, nonspecific-appearing skin eruption had increased antibody titers to antigens in the salivary glands of Aedes taeniorhynchus, a salt marsh mosquito common to South Florida. We hypothesize that the pruritus and skin le...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(89)80051-9

    authors: Penneys NS,Nayar JK,Bernstein H,Knight JW

    更新日期:1989-08-01 00:00:00

  • Amelanotic metastatic melanoma in a patient with oculocutaneous albinism.

    abstract::Melanomas are rare in patients who have albinism, compared with the frequent occurrence of squamous cell carcinomas and basal cell carcinomas. This report describes amelanotic metastatic melanoma in a 58-year-old Japanese man who had tyrosinase-positive oculocutaneous albinism. A prolonged bleeding time, facioscapuloh...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/0190-9622(93)70128-g

    authors: Ihn H,Nakamura K,Abe M,Furue M,Takehara K,Nakagawa H,Ishibashi Y

    更新日期:1993-05-01 00:00:00

  • Atypical fibroxanthoma: Systematic review and meta-analysis of treatment with Mohs micrographic surgery or excision.

    abstract:BACKGROUND:Atypical fibroxanthoma (AFX) is a fibrohistiocytic tumor with relatively high local recurrence rates but low metastatic potential. Wide local excision (WLE) and Mohs micrographic surgery (MMS) are common treatments, although no consensus exists regarding optimal therapy. OBJECTIVE:To systematically review e...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,meta分析

    doi:10.1016/j.jaad.2018.06.048

    authors: Tolkachjov SN,Kelley BF,Alahdab F,Erwin PJ,Brewer JD

    更新日期:2018-11-01 00:00:00

  • Minocycline-related lupus erythematosus with associated liver disease.

    abstract::A young woman developed minocycline-related lupus erythematosus with associated autoimmune hepatitis. All clinical and laboratory abnormalities returned to normal when the drug was stopped. The symptoms worsened dramatically upon rechallenge, strongly suggesting the reaction was related to the minocycline. ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(97)70043-4

    authors: Crosson J,Stillman MT

    更新日期:1997-05-01 00:00:00

  • Urticaria pigmentosa responsive to nifedipine.

    abstract::A patient with symptomatic urticaria pigmentosa who responded to nifedipine therapy is reported. Relief from cold-induced urtication and flushing was obtained with 10 mg taken orally three times daily. Calcium influx is an early step in the degranulation of mast cells. We hypothesize that the beneficial effect of nife...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(84)70233-7

    authors: Fairley JA,Pentland AP,Voorhees JJ

    更新日期:1984-10-01 00:00:00

  • Topical treatment for moccasin-type tinea pedis.

    abstract::Sixty patients were treated for tinea pedis with 2% topical ketoconazole cream either once or twice daily. All diagnoses were confirmed mycologically. They were randomly assigned in a double-blind study into three groups on the basis of their clinical lesions, that is, vesicular pedis, interdigital pedis, and hyperker...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 临床试验,杂志文章,随机对照试验

    doi:10.1016/s0190-9622(87)70073-5

    authors: Greer DL

    更新日期:1987-03-01 00:00:00

  • Xeroderma pigmentosum. A clinical study of 24 Libyan cases.

    abstract:BACKGROUND:Despite a high incidence of xeroderma pigmentosum, there is no previous publication from Libya. OBJECTIVE:The purpose was to study the clinical profile of Libyan cases of xeroderma pigmentosum. METHODS:With the help of a special protocol, 24 cases of xeroderma pigmentosum treated between 1981 and 1990 were...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(92)70010-d

    authors: Khatri ML,Shafi M,Mashina A

    更新日期:1992-01-01 00:00:00

  • Cutaneous wound healing: a model for cell-matrix interactions.

    abstract::Molecules of the extracellular matrix may influence the biologic behavior of basal cell keratinocytes. In the unwounded situation, basal cells are in contact with the basement membrane of the dermo-epidermal junction and eventually detach from this structure, move vertically, and differentiate. During wound healing th...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(85)80005-0

    authors: Woodley DT,O'Keefe EJ,Prunieras M

    更新日期:1985-02-01 00:00:00

  • A systematic review of adult-onset clinically amyopathic dermatomyositis (dermatomyositis siné myositis): a missing link within the spectrum of the idiopathic inflammatory myopathies.

    abstract:OBJECTIVE:Classical dermatomyositis (CDM) patients display the hallmark cutaneous manifestations of dermatomyositis (DM), proximal muscle weakness, and laboratory evidence of myositis. The epidemiology and management of both adult-onset and juvenile-onset CDM has been well characterized. However, the clinical significa...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2005.10.041

    authors: Gerami P,Schope JM,McDonald L,Walling HW,Sontheimer RD

    更新日期:2006-04-01 00:00:00

  • Dermal implants: safety of products injected for soft tissue augmentation.

    abstract::Soft tissue augmentation is a frequently performed outpatient operation. Products available for soft tissue augmentation vary in chemistry, clinical indications, and toxicity. This review examines safety and efficacy data for collagen implants (Zyderm and Zyplast), gelatin matrix implants (Fibrel), and injectable sili...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(89)70288-7

    authors: Clark DP,Hanke CW,Swanson NA

    更新日期:1989-11-01 00:00:00

  • Circulating adhesion molecules as prognostic factors for cutaneous melanoma.

    abstract:BACKGROUND:Overexpression of adhesion molecules in tissues of human neoplasms, including malignant melanoma, has been reported to be clinically relevant, but the predictive value of circulating adhesion molecules for clinical outcome and life expectancy in patients with primary malignant melanoma (PMM) and metastases o...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(97)70282-2

    authors: Schaider H,Rech-Weichselbraun I,Richtig E,Seidl H,Soyer HP,Smolle J,Kerl H

    更新日期:1997-02-01 00:00:00

  • Acitretin improves psoriasis in a dose-dependent fashion.

    abstract::Acitretin, a metabolite of etretinate, was given to 38 patients for the treatment of psoriasis. During the first 8 weeks patients received either placebo, 10 mg, 25 mg, 50 mg, or 75 mg of acitretin daily in a double-blind manner. The dosages of 10 mg and 25 mg daily did not achieve any statistically significant improv...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0190-9622(88)70086-9

    authors: Goldfarb MT,Ellis CN,Gupta AK,Tincoff T,Hamilton TA,Voorhees JJ

    更新日期:1988-04-01 00:00:00

  • Desmoplastic malignant melanoma of the lip: a report of 6 cases and review of the literature.

    abstract::Desmoplastic malignant melanoma is a rare neoplasm consisting primarily of spindle-shaped melanoma cells embedded in a fibrous stroma, with approximately 6% of cases occurring in the lip. A literature search revealed that most reported cases occur in sun-exposed areas in older men. Few cases of desmoplastic malignant ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1067/mjd.2002.124686

    authors: Hui JI,Linden KG,Barr RJ

    更新日期:2002-12-01 00:00:00

  • Synthetic membranes and cultured keratinocyte grafts.

    abstract::Significant progress has been made in skin replacement options in the past several decades. Although initially various materials have been used mainly for burn coverage, their application to dermatologic practice has increased significantly. We review the research, progress, and other aspects of wound coverage with sy...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/0190-9622(90)70279-q

    authors: Límová M,Grekin RC

    更新日期:1990-10-01 00:00:00

  • The significance of crystalline/chrysalis structures in the diagnosis of melanocytic and nonmelanocytic lesions.

    abstract:BACKGROUND:Crystalline/chrysalis structures (CS) are white shiny streaks that can only be seen with polarized dermatoscopy. OBJECTIVES:We sought to estimate the prevalence and assess the clinical significance of CS in melanocytic and nonmelanocytic lesions. METHODS:This was a prospective observational study in which ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2011.04.039

    authors: Balagula Y,Braun RP,Rabinovitz HS,Dusza SW,Scope A,Liebman TN,Mordente I,Siamas K,Marghoob AA

    更新日期:2012-08-01 00:00:00

  • Isotretinoin improves the appearance of photodamaged skin: results of a 36-week, multicenter, double-blind, placebo-controlled trial.

    abstract::Photodamaged skin occurs as a result of long-term exposure to ultraviolet radiation. The incidence of photodamage in European and North American populations with Fitzpatrick skin types I, II, and III is estimated at 80% to 90%. We conducted a double-blind clinical trial to test the efficacy and safety of 0.1% isotreti...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0190-9622(00)90009-4

    authors: Maddin S,Lauharanta J,Agache P,Burrows L,Zultak M,Bulger L

    更新日期:2000-01-01 00:00:00

  • Eccrine gland clear reticulated cytoplasm.

    abstract::This report relates how a normal variation of the eccrine secretory coil was mistaken for pathologic change. Electron microscopic studies of this variation, which to the best of our knowledge have not previously been reported, are presented. ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(85)70193-4

    authors: Burket JM,Brooks R,Burket DA

    更新日期:1985-09-01 00:00:00

  • Melanoma detection in British Columbia, Canada.

    abstract:BACKGROUND:In several studies, delays in malignant melanoma (MM) diagnosis have been correlated with increased tumor thickness, increased morbidity, and increased mortality. OBJECTIVE:We sought to assess how MM is detected in British Columbia, Canada, and to understand the role of patient education and other factors o...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2004.04.031

    authors: Tyler I,Rivers JK,Shoveller JA,Blum A

    更新日期:2005-01-01 00:00:00

  • Acquired brachial cutaneous dyschromatosis: a common pigmentary disorder of the arm in middle-aged women.

    abstract::We studied 20 Caucasian middle-aged patients, mostly women, who had asymptomatic, gray-brown patches with geographic borders, occasionally interspersed with hypopigmented macules, on the dorsum of the forearms, mostly bilaterally. The distal aspect of the arms was also involved in 2 patients; the face was always spare...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:

    authors: Rongioletti F,Rebora A

    更新日期:2000-04-01 00:00:00

  • Dermographism: a review.

    abstract::Urticaria is one of the more common skin conditions seen by physicians. Physical agents are an important cause of urticaria, with pressure or shearing forces being the most common. Dermographism is due to a combination of pressure and shearing forces and is present in a large number of healthy individuals. The purpose...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(84)70222-2

    authors: Wong RC,Fairley JA,Ellis CN

    更新日期:1984-10-01 00:00:00