Bath-PUVA therapy in three patients with scleredema adultorum.

Abstract:

BACKGROUND:Scleredema adultorum (SA) is a rare connective tissue disorder for which no treatment has proven to be effective. OBJECTIVE:Our purpose was to determine the effect of bath-PUVA therapy on SA. METHODS:Three patients were treated. Clinical evaluation of skin induration and thickness as well as ultrasonography were performed at baseline and after treatment. RESULTS:All three patients showed substantial clinical improvement with bath-PUVA therapy (median of 59 treatments and a cumulative UVA dose of 245.7 J/cm2). Ultrasonography showed significant reduction in both skin thickness and density. CONCLUSION:Bath-PUVA therapy appears to be effective in the treatment of SA.

journal_name

J Am Acad Dermatol

authors

Hager CM,Sobhi HA,Hunzelmann N,Wickenhauser C,Scharenberg R,Krieg T,Scharffetter-Kochanek K

doi

10.1016/s0190-9622(98)70244-0

subject

Has Abstract

pub_date

1998-02-01 00:00:00

pages

240-2

issue

2 Pt 1

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(98)70244-0

journal_volume

38

pub_type

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