The mast cell in health and disease.

Abstract:

:The presence of mast cells, often in an activated state or increased numbers, has been noted in various cutaneous disorders. Recent studies suggest that mast cells are of primary importance in these conditions and their presence does not merely represent a secondary event. This review focuses on atopic dermatitis, contact hypersensitivity reactions, bullous pemphigoid, fibrosing conditions, neurofibromatosis, wound healing, polycythemia vera, and psoriasis, in which there is significant evidence to indicate a pathophysiologic role for mast cells.

journal_name

J Am Acad Dermatol

authors

Rothe MJ,Nowak M,Kerdel FA

doi

10.1016/0190-9622(90)70264-i

subject

Has Abstract

pub_date

1990-10-01 00:00:00

pages

615-24

issue

4 Pt 1

eissn

0190-9622

issn

1097-6787

pii

0190-9622(90)70264-I

journal_volume

23

pub_type

杂志文章,评审
  • Immunosuppression is an independent prognostic factor associated with aggressive tumor behavior in cutaneous melanoma.

    abstract:BACKGROUND:A number of factors other than those identified by the American Joint Committee on Cancer (AJCC) may have prognostic significance in the evaluation of melanoma. OBJECTIVE:We sought to evaluate commonly recorded clinical features potentially associated with aggressive melanoma. METHODS:We conducted a retros...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2015.06.052

    authors: Donahue T,Lee CY,Sanghvi A,Obregon R,Sidiropoulos M,Cooper C,Merkel EA,Yélamos O,Ferris L,Gerami P

    更新日期:2015-09-01 00:00:00

  • The deep penetrating nevus.

    abstract::The deep penetrating nevus (DPN), also known as the plexiform spindle cell nevus, is a pigmented lesion that commonly arises on the head and neck in the first few decades of life. Histopathologically, the DPN is wedge-shaped and contains melanocytes that exhibit deep infiltration into the dermis. Given these features,...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2014.07.026

    authors: Strazzula L,Senna MM,Yasuda M,Belazarian L

    更新日期:2014-12-01 00:00:00

  • Severe sialadenitis: a new complication of drug reaction with eosinophilia and systemic symptoms.

    abstract:BACKGROUND:Drug cutaneous reaction and isolated cases of parotitis induced by terbinafine have been reported. OBSERVATION:We report a case of drug reaction with eosinophilia and systemic symptoms induced by terbinafine associated with a severe sialadenitis and a complete sicca syndrome. Evolution was protracted with a...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2004.06.023

    authors: Abecassis S,Roujeau JC,Bocquet H,Copie-Bergman C,Radier C,Revuz J,Cosnes A

    更新日期:2004-11-01 00:00:00

  • Immunosuppression may be present within condyloma acuminata.

    abstract:BACKGROUND:Condyloma acuminatum are common lesions caused by human papillomavirus (HPV). HPV is associated with many human cancers, and a vaccine now prevents infection with high-risk HPV. However, eradication of established disease is difficult, indicating that these lesions are capable of local immunosuppression. OB...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2008.08.011

    authors: Le Poole C,Denman CJ,Arbiser JL

    更新日期:2008-12-01 00:00:00

  • Congenital atrichia, palmoplantar hyperkeratosis, mental retardation, and early loss of teeth in four siblings: a new syndrome?

    abstract::A syndrome of congenital atrichia, palmoplantar hyperkeratosis, mental retardation, and early loss of teeth was observed in four siblings (three women and one man). The pedigree is suggestive of either an autosomal recessive mode of inheritance or the inheritance of a (small) chromosomal translocation. This combinatio...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(94)70108-3

    authors: Steijlen PM,Neumann HA,der Kinderen DJ,Smeets DF,van der Kerkhof PC,Happle R

    更新日期:1994-05-01 00:00:00

  • Simplified fixative medium for direct immunofluorescence in skin biopsies.

    abstract::The main limitation for the use of direct immunofluorescence in skin biopsies was the necessity for frozen tissue. In 1973 Michel et al reported use of a liquid fixative, consisting of ammonium sulfate, N-ethyl-maleimide, magnesium sulfate, and potassium citrate, for handling skin biopsy specimens. The present study i...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(85)70103-x

    authors: Niedecken HW,Lange CE

    更新日期:1985-05-01 00:00:00

  • Topical 5% imiquimod for the therapy of actinic cheilitis.

    abstract:BACKGROUND:Tissue-destructive and more selective cytotoxic therapies are the main methods used to treat actinic cheilitis. A topical immune stimulant, 5% imiquimod cream, has recently been used for treatment of cutaneous epithelial malignancies including squamous cell carcinoma in situ and basal cell carcinoma. OBJECT...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1067/mjd.2002.126266

    authors: Smith KJ,Germain M,Yeager J,Skelton H

    更新日期:2002-10-01 00:00:00

  • Cutaneous angiomas in POEMS syndrome.

    abstract::POEMS syndrome is an unusual plasma cell dyscrasia with multisystemic manifestations featuring polyneuropathy, organomegaly, endocrinopathy, M protein and constant skin involvement. We have seen a 58-year-old white man presenting with generalized eruptive angiomas as a rare skin manifestation of this syndrome. We revi...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(85)70123-5

    authors: Puig L,Moreno A,Domingo P,Llistosella E,de Moragas JM

    更新日期:1985-05-01 00:00:00

  • Collodion baby: an update with a focus on practical management.

    abstract::Collodion baby is an uncommon clinical presentation of several genetic conditions, primarily disorders of cornification. The severely compromised epidermal barrier presents the greatest challenge during the newborn period and advances in neonatal care have significantly improved the prognosis. This review summarizes t...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2012.05.036

    authors: Prado R,Ellis LZ,Gamble R,Funk T,Arbuckle HA,Bruckner AL

    更新日期:2012-12-01 00:00:00

  • Parakeratosis.

    abstract::The diagnostic value of parakeratosis is reviewed, with special emphasis on associated inflammatory tissue reaction patterns and the geometric pattern of the scale. Parakeratosis may also occur in disorders not primarily inflammatory in nature and those associations are addressed. Topics are divided into 6 categories:...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(03)02801-9

    authors: Brady SP

    更新日期:2004-01-01 00:00:00

  • Obsessive-compulsive disorder in patients with chronic pruritic conditions: case studies and discussion.

    abstract:BACKGROUND:Relatively few persons with obsessive-compulsive disorder (OCD) come to psychiatric clinics for treatment. Our hypothesis was that patients with a form of OCD that involves compulsive hand and body washing might initially seek treatment from a dermatologist. OBJECTIVE:Our purpose was to screen patients atte...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(92)70078-t

    authors: Hatch ML,Paradis C,Friedman S,Popkin M,Shalita AR

    更新日期:1992-04-01 00:00:00

  • The value of patch testing patients with a scattered generalized distribution of dermatitis: retrospective cross-sectional analyses of North American Contact Dermatitis Group data, 2001 to 2004.

    abstract:BACKGROUND:A scattered generalized distribution (SGD) of dermatitis is a challenging problem; patch testing is a strategy for evaluating allergic contact dermatitis as a relevant factor. OBJECTIVE:We sought to analyze patient characteristics and most frequently relevant positive allergens in patients presenting for pa...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2008.05.008

    authors: Zug KA,Rietschel RL,Warshaw EM,Belsito DV,Taylor JS,Maibach HI,Mathias CG,Fowler JF Jr,Marks JG Jr,DeLeo VA,Pratt MD,Sasseville D,Storrs FJ

    更新日期:2008-09-01 00:00:00

  • Necrolytic migratory erythema as the only presenting sign of a glucagonoma.

    abstract::We describe a 39-year-old man with a 3-year history of a recalcitrant psoriasiform eruption that was accentuated in the intertriginous areas. Hsitopathology was consistent with psoriasis. A glucagon level was 744 pg/mL with the upper limit of normal being 130 pg/mL. Computed tomographic scan of the abdomen revealed a ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1067/s0190-9622(02)61774-8

    authors: Johnson SM,Smoller BR,Lamps LW,Horn TD

    更新日期:2003-08-01 00:00:00

  • Mohs micrographic surgery for the treatment of primary cutaneous melanoma.

    abstract:BACKGROUND:Mohs micrographic surgery is thought to be a useful therapy for cutaneous melanoma. Controversy persists, however, because there are few published reports that document its safety and efficacy. OBJECTIVE:Our purpose was to determine the safety and efficacy of Mohs micrographic surgery for the treatment of c...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(97)80131-4

    authors: Zitelli JA,Brown C,Hanusa BH

    更新日期:1997-08-01 00:00:00

  • The ABCD rule of dermatoscopy. High prospective value in the diagnosis of doubtful melanocytic skin lesions.

    abstract:BACKGROUND:The difficulties in accurately assessing pigmented skin lesions are ever present in practice. The recently described ABCD rule of dermatoscopy (skin surface microscopy at x10 magnification), based on the criteria asymmetry (A), border (B), color (C), and differential structure (D), improved diagnostic accura...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(94)70061-3

    authors: Nachbar F,Stolz W,Merkle T,Cognetta AB,Vogt T,Landthaler M,Bilek P,Braun-Falco O,Plewig G

    更新日期:1994-04-01 00:00:00

  • Granular cell tumor. An analysis of 16 cases and review of the literature.

    abstract::Sixteen patients with granular cell tumors were seen between 1964 and 1979. The medical data of these patients showed an average age incidence of 39 years and a greater frequency among Negroes (69%) and in female patients (62.5%). The most common sign (in 12 of 16 patients) was the presence of an asymptomatic mass. Th...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(81)70085-9

    authors: Apisarnthanarax P

    更新日期:1981-08-01 00:00:00

  • Relationship between age and likelihood of lymph node metastases in patients with intermediate thickness melanoma (1.01-4.00 mm): A National Cancer Database study.

    abstract:BACKGROUND:There is large variability in the risk of sentinel lymph node (SLN) positivity among patients with intermediate thickness melanoma (ITM), with a subgroup of patients exhibiting a low risk of nodal disease. OBJECTIVE:To identify a group of patients with ITM for whom the risk of nodal disease is low. METHODS...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2018.08.022

    authors: Hanna AN,Sinnamon AJ,Roses RE,Kelz RR,Elder DE,Xu X,Pockaj BA,Zager JS,Fraker DL,Karakousis GC

    更新日期:2019-02-01 00:00:00

  • Cutaneous reactive angiomatoses: patterns and classification of reactive vascular proliferation.

    abstract::New and relatively old types of vascular (capillary) proliferations in the skin have been described or better categorized in the last few years. They include reactive angioendotheliomatosis, acroangiodermatitis (pseudo-Kaposi sarcoma), diffuse dermal angiomatosis, intravascular histocytosis, glomeruloid angioendotheli...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(03)02100-5

    authors: Rongioletti F,Rebora A

    更新日期:2003-11-01 00:00:00

  • The development of the patch testing procedure and working for consistency.

    abstract::Patch testing is a necessary tool to investigate contact dermatitis, which has developed alongside the increased knowledge of contact sensitivity in the past 100 years. The history of patch testing, the current state of the art with its problems, and future prospects are discussed. ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(89)70266-8

    authors: Hjorth N

    更新日期:1989-10-01 00:00:00

  • Interclinician agreement on the recognition of selected gross morphologic features of pigmented lesions. Studies of melanocytic nevi V.

    abstract:BACKGROUND:Since the late 1970s clinical criteria for dysplastic melanocytic nevi (DMN) have been proposed and discussed. However, to our knowledge, no rigorous quantitative evaluation of the ability of examiners to agree on the gross morphologic features ascribed to DMN or atypical melanocytic lesions in general has b...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(92)70023-9

    authors: Barnhill RL,Roush GC,Ernstoff MS,Kirkwood JM

    更新日期:1992-02-01 00:00:00

  • Papulosquamous diseases: a review.

    abstract::Papulosquamous diseases are a heterogeneous group of disorders whose etiology primarily is unknown. The nosology of these disorders is based on a descriptive morphology of clinical lesions characterized by scaly papules and plaques. The major entities in this group include psoriasis, parapsoriasis (including pityriasi...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(85)70084-9

    authors: Fox BJ,Odom RB

    更新日期:1985-04-01 00:00:00

  • The local treatment and available dressings designed for chronic wounds.

    abstract::The great diversity of wounds and the broad range of available dressings complicate the selection of proper chronic wound treatment. Choosing the right treatment is the essential step in the healing process. In this review, we focus on chronic nonhealing ulcers, which are a critical problem in clinical practice, and c...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2011.06.028

    authors: Skórkowska-Telichowska K,Czemplik M,Kulma A,Szopa J

    更新日期:2013-04-01 00:00:00

  • Treatment of nonmelanotic hyperpigmentation with the Q-switched ruby laser.

    abstract::Hyperpigmentation of the skin is often refractory to conventional therapies, but has significant cosmetic implications if located on visible areas. Because laser systems are capable of removing pigment deposits caused by selective photothermolysis, we addressed the issue of whether the Q-switched ruby laser could be a...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1067/mjd.2000.105555

    authors: Becker-Wegerich PM,Kuhn A,Malek L,Lehmann P,Megahed M,Ruzicka T

    更新日期:2000-08-01 00:00:00

  • Unusual manifestations of secondary syphilis and abnormal humoral immune response to Treponema pallidum antigens in a homosexual man with asymptomatic human immunodeficiency virus infection.

    abstract::The case presented here involves a 32-year-old homosexual man with human immunodeficiency virus (HIV) seropositivity and unusual manifestations of secondary syphilis. The patient presented with syphilitic keratoderma and chorioretinitis, and his appearance superficially resembled that of a patient with Reiter's syndro...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(88)70062-6

    authors: Radolf JD,Kaplan RP

    更新日期:1988-02-01 00:00:00

  • Neonatal bullous eruption as a result of transient porphyrinemia in a premature infant with hemolytic disease of the newborn.

    abstract::We describe the clinical and biochemical features of an infant with marked transient porphyrinemia in whom blistering developed while the infant was undergoing phototherapy for severe Rh isoimmunization. The cause of the transient porphyrinemia was likely to be multifactorial--abnormal porphyrin metabolism or accumula...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(95)91428-5

    authors: Mallon E,Wojnarowska F,Hope P,Elder G

    更新日期:1995-08-01 00:00:00

  • Suction blistering the lesional skin of vitiligo patients reveals useful biomarkers of disease activity.

    abstract:BACKGROUND:Vitiligo is an autoimmune disease of the skin with limited treatment options; there is an urgent need to identify and validate biomarkers of disease activity to support vitiligo clinical studies. OBJECTIVE:To investigate potential biomarkers of disease activity directly in the skin of vitiligo subjects and ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2016.12.021

    authors: Strassner JP,Rashighi M,Ahmed Refat M,Richmond JM,Harris JE

    更新日期:2017-05-01 00:00:00

  • Acanthosis nigricans: a cutaneous marker of tissue resistance to insulin.

    abstract::Tissue resistance to insulin is a major feature underlying the development of acanthosis nigricans in many patients. We report two unusual cases of acanthosis nigricans with contrasting forms of insulin resistance and propose an algorithm for the evaluation of patients with acanthosis nigricans. Further, we present a ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(89)70208-5

    authors: Rendon MI,Cruz PD Jr,Sontheimer RD,Bergstresser PR

    更新日期:1989-09-01 00:00:00

  • Betel: consumption and consequences.

    abstract::Betel is a compound of natural substances chewed for its psychostimulating effects. Betel is composed of the nut of the areca palm (Areca catechu), the leaf of the betel pepper (Piper betle), and lime (calcium hydroxide). Approximately 200 million persons chew betel regularly throughout the western Pacific basin and s...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(98)70543-2

    authors: Norton SA

    更新日期:1998-01-01 00:00:00

  • Benzoyl peroxide/clindamycin/UVA is more effective than fluticasone/UVA in progressive macular hypomelanosis: a randomized study.

    abstract:BACKGROUND:There is no effective treatment for progressive macular hypomelanosis. Recent findings indicate that Propionibacterium acnes may play a role in the pathogenesis. OBJECTIVES:We sought to compare the effectiveness of antimicrobial therapy with anti-inflammatory therapy in patients with progressive macular hyp...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jaad.2006.03.020

    authors: Relyveld GN,Kingswijk MM,Reitsma JB,Menke HE,Bos JD,Westerhof W

    更新日期:2006-11-01 00:00:00

  • Urticarial dermatitis: clinical features, diagnostic evaluation, and etiologic associations in a series of 146 patients at Mayo Clinic (2006-2012).

    abstract:BACKGROUND:Few studies have examined patients initially presenting with clinical features of urticarial dermatitis (UD). OBJECTIVE:We sought to examine clinical and laboratory evaluations and final diagnoses of patients with clinical features of UD. METHODS:This was a retrospective review of patients with UD seen at ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2013.08.050

    authors: Hannon GR,Wetter DA,Gibson LE

    更新日期:2014-02-01 00:00:00