Hepatobiliary pruritus: what are effective treatments?

abstract：BACKGROUND:The vulvovaginal gingival syndrome is an uncommon and severe variant of lichen planus characterized by erosions or desquamation of vulval, vaginal, and gingival mucosae with a predilection for scarring and stricture formation. OBJECTIVE:We sought to define the clinical, immunopathologic, and human leukocyte...

journal_title：Journal of the American Academy of Dermatology

authors： Setterfield JF,Neill S,Shirlaw PJ,Theron J,Vaughan R,Escudier M,Challacombe SJ,Black MM

更新日期：2006-07-01 00:00:00

abstract：:We report two cases in which dermatophytic infection developed almost entirely within a radiation field mimicking an acute radiation effect. Radiotherapists and dermatologists should be aware of this possibility and be able to differentiate it from radiation dermatitis. Topical antifungal agents are the recommended tr...

journal_title：Journal of the American Academy of Dermatology

authors： Rosen T,Dupuy J,Maor M,Altman A

更新日期：1988-12-01 00:00:00

abstract：:The second article in this continuing medical education series discusses cosmetic practices associated with cultural dermatoses, including hair care, traditional clothing, and skin decorations. Often, the steps individuals take to enhance their physical appearance are determined by cultural perceptions of beauty. With...

journal_title：Journal of the American Academy of Dermatology

authors： Vashi NA,Patzelt N,Wirya S,Maymone MBC,Kundu RV

更新日期：2018-07-01 00:00:00

abstract：:A number of dermatologic conditions may have associated esophageal manifestations. Teleologically, this may be because both the skin and the esophagus are lined by stratified squamous epithelium. Bullous dermatoses that may produce blisters, erosions, and/or stricture of the esophagus include cicatricial pemphigoid, H...

journal_title：Journal of the American Academy of Dermatology

authors： Kaplan RP,Touloukian J,Ahmed AR,Newcomer VD

更新日期：1981-06-01 00:00:00

abstract：:Dermatofibrosarcoma protuberans (DFSP) is a rare, clinically challenging, soft tissue tumor. The main histologic differential of DFSP is usually a dermatofibroma. In 1990, the first report appeared demonstrating that cells of DFSP express the human progenitor antigen CD34 on their surface. Since then, there have been ...

journal_title：Journal of the American Academy of Dermatology

authors： Haycox CL,Odland PB,Olbricht SM,Piepkorn M

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Cutaneous polyarteritis nodosa (cPAN) is a skin medium vessel neutrophilic arteritis with livedo, nodules, and ulcerations. Macular lymphocytic arteritis (MLA) is a small arteritis with erythematous or pigmented macules and typical histologic features (a lymphocytic infiltrate, concentric fibrin ring, no dis...

journal_title：Journal of the American Academy of Dermatology

authors： Buffiere-Morgado A,Battistella M,Vignon-Pennamen MD,de Masson A,Rybojad M,Petit A,Cordoliani F,Begon E,Flageul B,Mahr A,Bagot M,Bouaziz JD

更新日期：2015-12-01 00:00:00

abstract：:A new section entitled "Dermatology Grand Rounds at the NIH" appears this month. The idea behind it is to provide a unique look at instructive dermatologic cases being presented at the weekly Dermatology Branch Grand Rounds at the National Cancer Institute, National Institutes of Health (NIH), Bethesda, Maryland. Pati...

journal_title：Journal of the American Academy of Dermatology

authors： Blauvelt A,Cobb MW,Turner ML

更新日期：2000-10-01 00:00:00

abstract：:Both etretinate and its principal metabolite, acitretin, are efficacious in the treatment of psoriasis. Because patients with severe psoriasis often require chronic therapy, this study was undertaken to determine the efficacy, tolerability, and safety of acitretin in patients on continuous treatment for 12 months. The...

journal_title：Journal of the American Academy of Dermatology

authors： Murray HE,Anhalt AW,Lessard R,Schacter RK,Ross JB,Stewart WD,Geiger JM

更新日期：1991-04-01 00:00:00

abstract：:We describe a patient with chronic actinic dermatitis whose photopatch tests revealed reactions to musk ketone and musk ambrette, both of which were found in his aftershave lotion. Minimal erythema doses of UVA and UVB were decreased. After initial unsuccessful treatment with PUVA therapy the patient was successfully ...

journal_title：Journal of the American Academy of Dermatology

authors： Gardeazábal J,Arregui MA,Gil N,Landa N,Ratón JA,Diáz-Pérez JL

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:Lack of agreement on how to accurately capture disease outcomes in localized scleroderma (LS) has hindered the development of efficacious treatment protocols. The LS Cutaneous Assessment Tool (LoSCAT), consisting of the modified LS Skin Severity Index (mLoSSI) and the LS Damage Index, has potential for use i...

journal_title：Journal of the American Academy of Dermatology

authors： Kelsey CE,Torok KS

更新日期：2013-08-01 00:00:00

abstract：:A distinctive new hair condition, the loose anagen syndrome, features anagen hairs that are loosely anchored and easily pulled from the scalp. The children studied had sparse hair that did not grow long and that pulled easily from the scalp. The majority of patients were blond girls, aged 2 to 5 years, but both sexes ...

journal_title：Journal of the American Academy of Dermatology

authors： Price VH,Gummer CL

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:Increasing incidence and mortality rates from cutaneous melanoma are a major public health concern. As part of a national effort to enhance early detection of melanoma/skin cancer, the American Academy of Dermatology (AAD) has sponsored an annual education and early detection program that couples provision o...

journal_title：Journal of the American Academy of Dermatology

authors： Koh HK,Norton LA,Geller AC,Sun T,Rigel DS,Miller DR,Sikes RG,Vigeland K,Bachenberg EU,Menon PA,Billon SF,Goldberg G,Scarborough DA,Ramsdell WM,Muscarella VA,Lew RA

更新日期：1996-06-01 00:00:00

abstract：UNLABELLED:Sentinel lymph node biopsy for melanoma was introduced in the early 1990s as a minimally invasive method of identifying and pathologically staging regional lymph node basins in patients with clinical stage I/II melanoma. Numerous large trials have demonstrated that sentinel lymph node evaluation has utility ...

journal_title：Journal of the American Academy of Dermatology

authors： Stebbins WG,Garibyan L,Sober AJ

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Embryofetal developmental toxicity associated with oral administration of vitamin A analogs has led to concern about risks from topical application. OBJECTIVE:This study was conducted to evaluate the potential developmental toxicity of tretinoin emollient cream when applied to the skin of pregnant New Zeala...

journal_title：Journal of the American Academy of Dermatology

authors： Christian MS,Mitala JJ,Powers WJ Jr,McKenzie BE,Latriano L

更新日期：1997-03-01 00:00:00

abstract：:Vulvar melanosis is a condition in which intensely pigmented irregular macules, clinically mimicking malignant melanoma, appear on the vulva. A biopsy specimen shows only marked lower epidermal pigmentation without any melanocytic atypia or nesting. The process is benign, and reassurance is the only treatment. ...

journal_title：Journal of the American Academy of Dermatology

authors： Rudolph RI

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Laser resurfacing has been used for treatment of photoaged facial skin since late 1993. Very few long-term follow-up studies regarding the effectiveness and side effects of this procedure have been reported. METHOD:Patients who received carbon dioxide laser resurfacing for facial photoaging and wrinkling fr...

journal_title：Journal of the American Academy of Dermatology

authors： Manuskiatti W,Fitzpatrick RE,Goldman MP

更新日期：1999-03-01 00:00:00

abstract：BACKGROUND:HLA-DR1 is associated with the development of multiple basal cell carcinomas (BCC). However, the association is weak. OBJECTIVE:The purpose of our study was to determine whether HLA-DR1 is a marker for susceptibility to the development of many BCCs during a lifetime. METHODS:Persons with multiple BCCs were...

journal_title：Journal of the American Academy of Dermatology

authors： Czarnecki D,Lewis A,Nicholson I,Tait B,Nash C

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Ultraviolet B phototherapy is underused because of costs and inconvenience. Home phototherapy may alleviate these issues, but training is spotty, and many physicians are not comfortable prescribing home phototherapy. OBJECTIVE:The purpose of this review is to provide a practical guide for recognizing approp...

journal_title：Journal of the American Academy of Dermatology

authors： Anderson KL,Feldman SR

更新日期：2015-05-01 00:00:00

abstract：:The advent of new topical agents such as topical calcineurin inhibitors, as well as the reformulations of older agents in new vehicles, has broadened the treatment approaches to psoriasis and atopic dermatitis. The clinician must now consider additional novel physiologic pathways and mechanisms of action as well as ex...

journal_title：Journal of the American Academy of Dermatology

authors： Norris DA

更新日期：2005-07-01 00:00:00

abstract：:Neutrophilic dermatoses are a heterogeneous group of inflammatory skin disorders that present with unique clinical features but are unified by the presence of a sterile, predominantly neutrophilic infiltrate on histopathology. The morphology of cutaneous lesions associated with these disorders is heterogeneous, which ...

journal_title：Journal of the American Academy of Dermatology

authors： Nelson CA,Stephen S,Ashchyan HJ,James WD,Micheletti RG,Rosenbach M

更新日期：2018-12-01 00:00:00

abstract：:The first reported case of phenytoin-induced generalized nodular cutaneous pseudolymphoma without symptoms of the phenytoin hypersensitivity syndrome is presented. Despite the malignant histologic appearance of the dermal infiltrate, T-cell receptor gene rearrangement studies did not demonstrate monoclonality. The cut...

journal_title：Journal of the American Academy of Dermatology

authors： Braddock SW,Harrington D,Vose J

更新日期：1992-08-01 00:00:00

abstract：:The clinical and histologic features of 26 cases of erythema induratum are reviewed. The characteristic cutaneous lesions on the legs of middle-aged women were violaceous, indurated nodules, 1 to 2 cm in diameter, which were painful, occasionally ulcerated, and could heal with scarring. The diagnosis was confirmed in ...

journal_title：Journal of the American Academy of Dermatology

authors： Rademaker M,Lowe DG,Munro DD

更新日期：1989-10-01 00:00:00

abstract：:We describe a patient with vitamin A deficiency phrynoderma caused by a combination of inadequate dietary intake of vitamin A and beta-carotene and malabsorption secondary to primary visceral myopathy and total colectomy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Bleasel NR,Stapleton KM,Lee MS,Sullivan J

更新日期：1999-08-01 00:00:00

abstract：:Psoriasis is a common, chronic, inflammatory, multisystem disease with predominantly skin and joint manifestations affecting approximately 2% of the population. In this first of 5 sections of the guidelines of care for psoriasis, we discuss the classification of psoriasis; associated comorbidities including autoimmune...

journal_title：Journal of the American Academy of Dermatology

authors： Menter A,Gottlieb A,Feldman SR,Van Voorhees AS,Leonardi CL,Gordon KB,Lebwohl M,Koo JY,Elmets CA,Korman NJ,Beutner KR,Bhushan R

更新日期：2008-05-01 00:00:00

abstract：:Magnification of histologic and ultrastructural photoimages is frequently misrepresented in published reports. "Power," P, the usual mode of representation of magnification, is defined as the ratio of the distance between two points on the photoimage to that between the same two points on the original specimen, but is...

journal_title：Journal of the American Academy of Dermatology

authors： Lambert WC,Lambert MW

更新日期：1985-09-01 00:00:00

abstract：BACKGROUND:Teledermatology programs in the United States have evolved over the past several decades. No systematic survey of teledermatology programs in the United States is available in peer-reviewed literature. OBJECTIVE:To provide up-to-date information regarding the state of teledermatology programs in the United ...

journal_title：Journal of the American Academy of Dermatology

authors： Armstrong AW,Wu J,Kovarik CL,Goldyne ME,Oh DH,McKoy KC,Shippy AM,Pak HS

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:Keratoacanthomas usually occur spontaneously as a single rapidly growing tumor on sun-exposed skin. Multiple keratoacanthomas are rarely seen. Keratoacanthomas may also develop after trauma, laser resurfacing, radiation therapy, and at the donor site after skin grafting. OBJECTIVE:We report 6 cases of kerat...

journal_title：Journal of the American Academy of Dermatology

authors： Goldberg LH,Silapunt S,Beyrau KK,Peterson SR,Friedman PM,Alam M

更新日期：2004-05-01 00:00:00

abstract：:The early experiments of Marion B. Sulzberger suggested that the skin played a vital role in the generation of allergic contact dermatitis and other delayed type hypersensitivity reactions. This lecture is presented in the historical context of Dr. Sulzberger's lifework and interest in mechanisms involved in delayed t...

journal_title：Journal of the American Academy of Dermatology

authors： Katz SI

更新日期：1985-09-01 00:00:00

abstract：:The primary serum proteinase inhibitor is alpha 1-antitrypsin, and deficiency of this enzyme has been associated with a variety of systemic and cutaneous disorders. We report cutaneous vasculitis in a 49-year-old man with alpha 1-antitrypsin deficiency. His condition persisted despite treatment with colchicine, predni...

journal_title：Journal of the American Academy of Dermatology

authors： Dowd SK,Rodgers GC,Callen JP

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:The color, architecture, symmetry, and homogeneity (CASH) algorithm for dermoscopy includes a feature not used in prior algorithms, namely, architecture. Architectural order/disorder is derived from current concepts regarding the biology of benign versus malignant melanocytic neoplasms. OBJECTIVE:We sought ...

journal_title：Journal of the American Academy of Dermatology

authors： Henning JS,Dusza SW,Wang SQ,Marghoob AA,Rabinovitz HS,Polsky D,Kopf AW

更新日期：2007-01-01 00:00:00