Generalized nodular cutaneous pseudolymphoma associated with phenytoin therapy. Use of T-cell receptor gene rearrangement in diagnosis and clinical review of cutaneous reactions to phenytoin.

abstract：:Langerhans cell histiocytosis (LCH) is regarded as a disorder of histiocytic cell proliferation of the Langerhans type, probably resulting from altered immunoregulation. Cutaneous involvement is frequent and often appears as a scaling papular eruption that resembles seborrheic dermatitis; when limited to the scalp, sc...

journal_title：Journal of the American Academy of Dermatology

authors： Pakula AS,Paller AS

更新日期：1993-08-01 00:00:00

abstract：BACKGROUND:Since the late 1970s clinical criteria for dysplastic melanocytic nevi (DMN) have been proposed and discussed. However, to our knowledge, no rigorous quantitative evaluation of the ability of examiners to agree on the gross morphologic features ascribed to DMN or atypical melanocytic lesions in general has b...

journal_title：Journal of the American Academy of Dermatology

authors： Barnhill RL,Roush GC,Ernstoff MS,Kirkwood JM

更新日期：1992-02-01 00:00:00

abstract：BACKGROUND:It is unclear whether the type 2 T helper cell-specific immunosuppressive action of dupilumab interferes with patch testing. OBJECTIVES:We sought to evaluate the reliability of patch testing on dupilumab and the contribution of allergic contact dermatitis (ACD) to complex dermatitis in patients with residua...

journal_title：Journal of the American Academy of Dermatology

authors： Raffi J,Suresh R,Botto N,Murase JE

更新日期：2020-01-01 00:00:00

abstract：BACKGROUND:Onychomycosis is observed less frequently in children than adults. Until recently management of onychomycosis in children included topical formulations, oral griseofulvin, and in some cases deferral of treatment. OBJECTIVE:We attempted to determine the prevalence of onychomycosis in North American children ...

journal_title：Journal of the American Academy of Dermatology

authors： Gupta AK,Sibbald RG,Lynde CW,Hull PR,Prussick R,Shear NH,De Doncker P,Daniel CR 3rd,Elewski BE

更新日期：1997-03-01 00:00:00

abstract：:Thrombocytopenia was observed in 3 patients with cutaneous angiosarcoma of the scalp and face. A sudden decrease in the platelet count occurred in association with rapid enlargement of primary or metastatic lesions. Neither antiplatelet antibody nor platelet-associated IgG was detected. Increased serum levels of beta-...

journal_title：Journal of the American Academy of Dermatology

authors： Satoh T,Takahashi Y,Yokozeki H,Katayama I,Nishioka K

更新日期：1999-05-01 00:00:00

abstract：:We present the case of an American adult patient with eosinophilic pustular folliculitis. The majority of previously reported patients have been Japanese. Eosinophilic pustular folliculitis is a rare condition characterized by recurrent, peripherally expanding, sterile papulopustules and plaques. Hair-bearing areas su...

journal_title：Journal of the American Academy of Dermatology

authors： Jaliman HD,Phelps RG,Fleischmajer R

更新日期：1986-03-01 00:00:00

abstract：:Cutaneous extramedullary hemopoiesis (EMH) is a rare complication of chronic myeloproliferative and myelodysplastic disorders. Chronic idiopathic myelofibrosis (CIMF) is the most common underlying condition. To date, fewer than 30 cases have been reported in the literature and there has been significant confusion with...

journal_title：Journal of the American Academy of Dermatology

authors： Haniffa MA,Wilkins BS,Blasdale C,Simpson NB

更新日期：2006-08-01 00:00:00

abstract：:Mycobacterium avium complex, a common opportunistic pathogen among patients with AIDS, usually manifests as disseminated disease involving the lung, lymph nodes, and gastrointestinal tract. Primary cutaneous infections with M avium complex are extremely rare, and most cutaneous lesions are caused by dissemination. Cut...

journal_title：Journal of the American Academy of Dermatology

authors： Kayal JD,McCall CO

更新日期：2002-11-01 00:00:00

abstract：:A tense yellow vesicle was noted on the back parietal scalp of a female newborn. This proved to be a bullous variant of aplasia cutis congenita. Only 16 cases of this apparently rare disorder have been previously reported. Histologic evaluation of such lesions reveals a distinct pattern containing fibrovascular stroma...

journal_title：Journal of the American Academy of Dermatology

authors： Colon-Fontanez F,Fallon Friedlander S,Newbury R,Eichenfield LF

更新日期：2003-05-01 00:00:00

abstract：:We report the case of a 29-year-old transsexual who developed Mycobacterium abscessus infection after receiving intramammary liquid silicone injections in the nonphysician office setting. Our patient represents 1 of 14 confirmed and 11 suspected cases in New York City of M abscessus infection after illicit cosmetic pr...

journal_title：Journal of the American Academy of Dermatology

authors： Fox LP,Geyer AS,Husain S,Della-Latta P,Grossman ME

更新日期：2004-03-01 00:00:00

abstract：BACKGROUND:Often after biopsy a skin cancer appears to resolve clinically and a repeat biopsy may be done on the area in question before proceeding with further treatment. OBJECTIVE:Our purpose was to assess the value of a subsequent biopsy in the treatment of skin cancers previously diagnosed by biopsy results. METH...

journal_title：Journal of the American Academy of Dermatology

authors： Torres A,Seeburger J,Robison D,Glogau R

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:The tumor necrosis factor (TNF) inhibitor etanercept has been demonstrated to be safe and effective for treating chronic plaque psoriasis in 3 clinical trials. OBJECTIVES:To refine efficacy results for etanercept on the basis of a larger population size through the integration of the 3 studies, and to deter...

journal_title：Journal of the American Academy of Dermatology

authors： Gordon K,Korman N,Frankel E,Wang H,Jahreis A,Zitnik R,Chang T

更新日期：2006-03-01 00:00:00

abstract：:The responses to aggressive gluten challenge of two dermatitis herpetiformis patients with normal gut mucosa and negative serum findings for IgA endomysial antibodies while on normal diets indicate that these patients have a latent gluten-sensitive enteropathy. This was shown further by the control of skin lesions in ...

journal_title：Journal of the American Academy of Dermatology

authors： Chorzelski TP,Rosinska D,Beutner EH,Sulej J,Kumar V

更新日期：1988-04-01 00:00:00

abstract：:A 56-year-old man had a deeply invasive leiomyosarcoma of the right buttock. Leiomyosarcomas of the skin and subcutaneous tissues are rare, and most occur on the extremities. Wide local excision is the therapy of choice. ...

journal_title：Journal of the American Academy of Dermatology

authors： Landry MM,Sarma DP,Boucree JB Jr

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Several changing clinical and histopathologic melanoma trends occurred from the 1950s to the 1980s. OBJECTIVE:The purpose of this study was to evaluate melanoma trends during the past decade and to compare present trends to those documented during the past four decades. METHODS:Sex, age at diagnosis, locat...

journal_title：Journal of the American Academy of Dermatology

authors： Johnson TM,Dolan OM,Hamilton TA,Lu MC,Swanson NA,Lowe L

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Risk of cutaneous melanoma is increased among organ transplant recipients (OTRs) but outcome has rarely been evaluated. OBJECTIVE:We sought to assess melanoma characteristics and prognosis among OTRs versus the general population. METHODS:Using Swedish health care registers, we identified melanomas in OTRs...

journal_title：Journal of the American Academy of Dermatology

authors： Krynitz B,Rozell BL,Lyth J,Smedby KE,Lindelöf B

更新日期：2015-07-01 00:00:00

abstract：:Blistering of light-exposed skin, pink-stained fluorescing diapers, and fluorescing peripheral erythrocytes led to diagnosis of congenital porphyria in an infant born to consanguineous parents. Although massive coproporphyrinuria and coproporphyrinemia initially suggested a coproporphyrinogen oxidase deficiency disord...

journal_title：Journal of the American Academy of Dermatology

authors： Huang JL,Zaider E,Roth P,Garcia O,Pollack S,Poh-Fitzpatrick MB

更新日期：1996-05-01 00:00:00

abstract：:A case of phaeohyphomycosis caused by Phialophora richardsiae is presented. The patient was a 30-year-old man with end stage malignant lymphoma. A subcutaneous abscess that developed on the dorsum of the right foot was removed surgically but immediately recurred. The causative mold was isolated from the pus in the les...

journal_title：Journal of the American Academy of Dermatology

authors： Ikai K,Tomono H,Watanabe S

更新日期：1988-09-01 00:00:00

abstract：:A 43-year-old man with ulcerous granulomatous cheilitis and submaxillary lymph node invasion caused by Scopulariopsis brevicaulis infection is described. Administration of itraconazole produced a dramatic and definitive cure. Reported cases of deep mycosis caused by S. brevicaulis infection are also reviewed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Creus L,Umbert P,Torres-Rodríguez JM,López-Gil F

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Small open studies of patients at high risk for squamous cell carcinoma (SCC) of the skin suggest that oral retinoid use reduces the risk of these tumors. Among patients at lower risk, randomized trials of low doses of retinoids did not demonstrate significant chemopreventive effects. Patients with psoriasis...

journal_title：Journal of the American Academy of Dermatology

authors： Nijsten TE,Stern RS

更新日期：2003-10-01 00:00:00

abstract：BACKGROUND:Despite a high incidence of xeroderma pigmentosum, there is no previous publication from Libya. OBJECTIVE:The purpose was to study the clinical profile of Libyan cases of xeroderma pigmentosum. METHODS:With the help of a special protocol, 24 cases of xeroderma pigmentosum treated between 1981 and 1990 were...

journal_title：Journal of the American Academy of Dermatology

authors： Khatri ML,Shafi M,Mashina A

更新日期：1992-01-01 00:00:00

abstract：UNLABELLED:Sentinel lymph node biopsy for melanoma was introduced in the early 1990s as a minimally invasive method of identifying and pathologically staging regional lymph node basins in patients with clinical stage I/II melanoma. Numerous large trials have demonstrated that sentinel lymph node evaluation has utility ...

journal_title：Journal of the American Academy of Dermatology

authors： Stebbins WG,Garibyan L,Sober AJ

更新日期：2010-05-01 00:00:00

abstract：BACKGROUND:Hyperlipidemia has received little attention as a side effect of cyclosporine therapy for severe psoriasis. OBJECTIVE:We report changes in fasting serum lipids in patients treated with low-dose oral cyclosporine for psoriasis and discuss their significance. METHODS:Twenty-two patients with severe, recalcit...

journal_title：Journal of the American Academy of Dermatology

authors： Stiller MJ,Pak GH,Kenny C,Jondreau L,Davis I,Wachsman S,Shupack JL

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Spironolactone is used off-label for androgenic alopecia because of its ability to arrest hair loss progression and long-term safety profile. However, little is known about the safety of spironolactone in breast cancer (BC) survivors. Because spironolactone has estrogenic effects, there is a theoretical risk...

journal_title：Journal of the American Academy of Dermatology

authors： Wei C,Bovonratwet P,Gu A,Moawad G,Silverberg JI,Friedman AJ

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:Vascular cell adhesion molecule-1 (VCAM-1) is an endothelial protein with adhesive properties for inflammatory cells including lymphocytes. Its role in skin disease and regulation in vivo are uncertain. OBJECTIVE:Our purpose was to determine expression of VCAM-1 in normal and inflamed skin and the effect on...

journal_title：Journal of the American Academy of Dermatology

authors： Groves RW,Ross EL,Barker JN,MacDonald DM

更新日期：1993-07-01 00:00:00

abstract：:A set of three comparison studies under varying conditions was performed to determine the efficacy of a cotton swab technic for obtaining material for culture of dermatophyte infections. Matched fungal cultures, one by swab and one by scrape, on each of 110 subjects showed that there was no difference in the two metho...

journal_title：Journal of the American Academy of Dermatology

authors： Head ES,Henry JC,Macdonald EM

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Hypopigmentation is an adverse outcome associated with carbon-dioxide (CO(2)) laser resurfacing. A 90-microsecond pulse produces a more favorable postoperative course of healing, erythema, and pain compared with a 900-microsecond dwell time. The rate of hypopigmentation after 90-microsecond pulsed CO(2) resu...

journal_title：Journal of the American Academy of Dermatology

authors： Lewis KG,Nahm WK,Schmidt AN,Moy RL

更新日期：2004-02-01 00:00:00

abstract：:UVB irradiation is known to produce DNA damage at mutation hotspots in the p53 tumor suppressor gene, leading to the development of skin cancers. Mutations in the PTCH tumor suppressor gene, which is known to be responsible for the development of nevoid basal cell carcinoma syndrome, have also been identified in spora...

journal_title：Journal of the American Academy of Dermatology

authors： Ratner D,Peacocke M,Zhang H,Ping XL,Tsou HC

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:In primary melanomas, data on the degree of intratumoral heterogeneity to date have been lacking. OBJECTIVE:Our purpose was to investigate intratumoral DNA stem-line heterogeneity in superficial spreading melanoma (SSM). METHODS:Multiple measuring fields of 54 SSMs (tumor thickness median 1.60 mm) were stu...

journal_title：Journal of the American Academy of Dermatology

authors： Helmbold P,Altrichter D,Klapperstück T,Marsch WCh

更新日期：2005-05-01 00:00:00

abstract：:Skin specimens from five mummies were examined histologically. The specimens ranged in age from 2,000 to 3,200 years. Material from two mummies had carbonized and showed only amorphous debris. The histology of the three remaining skin fragments retained surprising histologic architectural detail. One specimen obtained...

journal_title：Journal of the American Academy of Dermatology

authors： Chapel TA,Mehregan AH,Reyman TA

更新日期：1981-01-01 00:00:00