Genital herpes: an integrated approach to management.

abstract：BACKGROUND:The incidence of delayed pressure urticaria (DPU) may have been underestimated, particularly in patients with widespread wheals of concurrent idiopathic urticaria, because of difficulty in recognizing the association between pressure-related swellings and the preceding physical stimulus. Diagnostic tests for...

journal_title：Journal of the American Academy of Dermatology

authors： Barlow RJ,Warburton F,Watson K,Black AK,Greaves MW

更新日期：1993-12-01 00:00:00

abstract：BACKGROUND:Lentigo maligna (LM) often displays extensive subclinical spread. Mohs micrographic surgery (MMS) has been proposed to help delineate the true histologic margin; however, visualizing atypical melanocytes on frozen section is challenging and often requires confirmatory permanent paraffin sections. OBJECTIVE:...

journal_title：Journal of the American Academy of Dermatology

authors： Kelley LC,Starkus L

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Established data confirm an increased incidence of skin cancer, mainly squamous cell carcinoma (SCC), in long-term kidney transplant recipients (KTRs). OBJECTIVE:Our purpose was to investigate prospectively the type and frequency of neoplastic and preneoplastic skin lesions in KTRs during the first 3 years ...

journal_title：Journal of the American Academy of Dermatology

authors： Ferrándiz C,Fuente MJ,Ribera M,Bielsa I,Fernández MT,Lauzurica R,Roca J

更新日期：1995-10-01 00:00:00

abstract：:Intravascular lymphomatosis (IVL) is a rare type of lymphoma with a poor prognosis. Its distinctive clinical and histopathologic features are generated by the proliferation of neoplastic mononuclear cells within blood vessels. We describe a patient with IVL of the skin as a manifestation of a recurrent diffuse large B...

journal_title：Journal of the American Academy of Dermatology

authors： Asagoe K,Fujimoto W,Yoshino T,Mannami T,Liu Y,Kanzaki H,Arata J

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Non-adherence rates are high among patients with psoriasis, partly because of discordance between recommended treatments and individual preferences. OBJECTIVES:Our aim was to assess the impact of comorbidities on patients' preferences for psoriasis treatments. METHODS:A computer-based conjoint analysis exp...

journal_title：Journal of the American Academy of Dermatology

authors： Schmieder A,Schaarschmidt ML,Umar N,Terris DD,Goebeler M,Goerdt S,Peitsch WK

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Clinical and histopathologic assessment of pigmented skin lesions remains challenging even for experts. Differentiated and accurate noninvasive diagnostic modalities are highly desirable. OBJECTIVE:We sought to provide clinicians with such a tool. METHODS:A 2-gene classification method based on LINC00518 a...

journal_title：Journal of the American Academy of Dermatology

authors： Gerami P,Yao Z,Polsky D,Jansen B,Busam K,Ho J,Martini M,Ferris LK

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Treatment of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) remains controversial. OBJECTIVE:We sought to evaluate the impact of cyclosporine on hospital mortality in patients with SJS/TEN. METHODS:All patients with SJS and TEN admitted to our center from 2011 to 2014 were treated unde...

journal_title：Journal of the American Academy of Dermatology

authors： Lee HY,Fook-Chong S,Koh HY,Thirumoorthy T,Pang SM

更新日期：2017-01-01 00:00:00

abstract：:Pyoderma gangrenosum is a neutrophilic dermatosis that may be associated with myeloid malignancies. Less information is available about the association of pyoderma gangrenosum with lymphoid malignancies. We present, to our knowledge, the first case of pyoderma gangrenosum associated with biphenotypic acute leukemia wh...

journal_title：Journal of the American Academy of Dermatology

authors： Asai M,Aragane Y,Kawada A,Shimada T,Kanamaru A,Yamada H,Tezukam T

更新日期：2001-03-01 00:00:00

abstract：BACKGROUND:Psoriasis is a systemic inflammatory condition that is associated with a higher risk of cardiovascular (CV) disease. Tofacitinib is being investigated as a treatment for psoriasis. OBJECTIVE:We sought to evaluate the effects of tofacitinib on CV risk factors and major adverse CV events (MACEs) in patients w...

journal_title：Journal of the American Academy of Dermatology

authors： Wu JJ,Strober BE,Hansen PR,Ahlehoff O,Egeberg A,Qureshi AA,Robertson D,Valdez H,Tan H,Wolk R

更新日期：2016-11-01 00:00:00

abstract：:The increased use of isotretinoin therapy for severe cystic acne has posed new problems for dermatologic surgeons. There have been recent reports in the literature of unexpected "atypical" scarring after dermabrasion in patients who have previously taken isotretinoin. This scarring was considered atypical because it o...

journal_title：Journal of the American Academy of Dermatology

authors： Katz BE,Mac Farlane DF

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Some studies have shown that switching patients from one tumor necrosis factor (TNF)-alfa inhibitor to another may be beneficial when they have an inadequate response or an adverse event. OBJECTIVE:We sought to assess the variables predicting the efficacy of the second TNF-alfa inhibitor in patients discont...

journal_title：Journal of the American Academy of Dermatology

authors： Piaserico S,Cazzaniga S,Chimenti S,Giannetti A,Maccarone M,Picardo M,Peserico A,Naldi L,Psocare Study Group.

更新日期：2014-02-01 00:00:00

abstract：:Pruritus is a common and often times difficult to treat symptom in many dermatologic and systemic diseases. For pruritus with an inflammatory or autoimmune origin, therapies such as topical corticosteroids and antihistamines are often initiated. However, in the case that these and additional systemic therapies are ine...

journal_title：Journal of the American Academy of Dermatology

authors： Sharma D,Kwatra SG

更新日期：2016-02-01 00:00:00

abstract：:The Norwegian-Russian border area is polluted because of emissions from two local Russian nickel refineries. We patch tested the general adult population on both sides of the border. Only 7.2% of the Russian women were sensitized to nickel, compared with 27.5% of the Norwegian women. We suggest that long-term exposure...

journal_title：Journal of the American Academy of Dermatology

authors： Smith-Sivertsen T,Tchachtchine V,Lund E

更新日期：2002-03-01 00:00:00

abstract：BACKGROUND:The incidence of cutaneous nontuberculous mycobacteria (NTM) infections is increasing. These infections are a diagnostic and therapeutic challenge. OBJECTIVE:We investigated the clinical features, diagnosis, and management of cutaneous NTM infections. METHODS:A retrospective case series studied 78 patients...

journal_title：Journal of the American Academy of Dermatology

authors： Philips RC,Hoyer PE,White SM,Tinkey KT,Loeffelholz M,Andersen CR,Wilkerson MG,Gibson BR,Kelly BC

更新日期：2019-09-01 00:00:00

abstract：:Several infections contracted in utero result in similar physical and laboratory findings during the neonatal period; the TORCH syndrome encompasses such patients. Skin lesions are a frequent finding and the dermatologist may play an important role in the early evaluation of these infants. In this review we discuss et...

journal_title：Journal of the American Academy of Dermatology

authors： Fine JD,Arndt KA

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:Although twice-daily application of propylene glycol-containing 2% minoxidil topical solution (MTS) stimulates new hair growth, higher concentrations of minoxidil in a once-daily, propylene glycol-free formulation may improve efficacy and reduce unpleasant side effects. OBJECTIVE:We sought to compare the ef...

journal_title：Journal of the American Academy of Dermatology

authors： Blume-Peytavi U,Hillmann K,Dietz E,Canfield D,Garcia Bartels N

更新日期：2011-12-01 00:00:00

abstract：:Thirty-two patients with acne completed a randomized, double-blind study using topical 1% clindamycin phosphate or its vehicle applied twice daily for 8 weeks for a study of its effects on the intestinal microflora. Two clindamycin patients and one vehicle patient had Clostridium difficile in stools prior to therapy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Siegle RJ,Fekety R,Sarbone PD,Finch RN,Deery HG,Voorhees JJ

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:Primary prevention of skin cancer must start early in life to reduce total life-time sun exposure and severe overexposure in childhood. Childhood is an excellent time to form life-long prevention habits. A school-based curriculum can be an effective prevention strategy. OBJECTIVE:Our purpose was to determin...

journal_title：Journal of the American Academy of Dermatology

authors： Buller DB,Buller MK,Beach B,Ertl G

更新日期：1996-12-01 00:00:00

abstract：BACKGROUND:Very low vitamin D levels have been noted in patients with a variety of autoimmune diseases. OBJECTIVE:To determine whether low vitamin D levels are associated with autoimmunity in the setting of vitiligo vulgaris. METHODS:A prospective cohort study was conducted on 45 consecutive patients with vitiligo vu...

journal_title：Journal of the American Academy of Dermatology

authors： Silverberg JI,Silverberg AI,Malka E,Silverberg NB

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:Often after biopsy a skin cancer appears to resolve clinically and a repeat biopsy may be done on the area in question before proceeding with further treatment. OBJECTIVE:Our purpose was to assess the value of a subsequent biopsy in the treatment of skin cancers previously diagnosed by biopsy results. METH...

journal_title：Journal of the American Academy of Dermatology

authors： Torres A,Seeburger J,Robison D,Glogau R

更新日期：1992-07-01 00:00:00

abstract：BACKGROUND:Epidermolysis bullosa (EB) is a genetic, heterogeneous, trauma-induced blistering disease. Patients with laminin-332-deficient non-Herlitz junctional EB (JEB-nH) can have impaired wound healing witnessed by persistent, small, deep ulcers on the hands and feet that adversely affect the quality of life. OBJEC...

journal_title：Journal of the American Academy of Dermatology

authors： Yuen WY,Huizinga J,Jonkman MF

更新日期：2013-01-01 00:00:00

abstract：:An association between HLA-DR1 and the development of multiple basal cell carcinomas was detected in southern Australia. A reduction in HLA-DR4 was found in patients with basal cell carcinoma compared with a local control group. The relative risk for HLA-DR1 was 2.1, which was lower than that for persons in farther co...

journal_title：Journal of the American Academy of Dermatology

authors： Czarnecki D,Lewis A,Nicholson I,Tait B

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Acne is a multifactorial disease in which androgens appear to play an important role. A low-dose oral contraceptive containing 20 microg of ethinyl estradiol and 100 microg of levonorgestrel (EE/LNG) has been shown to improve biochemical markers of androgenicity. Lowering bioavailable androgens may improve a...

journal_title：Journal of the American Academy of Dermatology

authors： Leyden J,Shalita A,Hordinsky M,Swinyer L,Stanczyk FZ,Weber ME

更新日期：2002-09-01 00:00:00

abstract：:Global temperatures continue to rise, reaching new records almost every year this decade. Although the causes are debated, climate change is a reality. Consequences of climate change include melting of the arctic ice cap, rising of sea levels, changes in precipitation patterns, and increased severe weather events. Thi...

journal_title：Journal of the American Academy of Dermatology

authors： Kaffenberger BH,Shetlar D,Norton SA,Rosenbach M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Many drugs have been used to treat scabies, but it is unclear which of them is the most efficacious. OBJECTIVE:To evaluate the comparative efficacy and safety of antiscabietic agents. METHODS:A systematic review of randomized controlled trials was conducted. Direct and network meta-analyses were applied to...

journal_title：Journal of the American Academy of Dermatology

authors： Thadanipon K,Anothaisintawee T,Rattanasiri S,Thakkinstian A,Attia J

更新日期：2019-05-01 00:00:00

abstract：:A 4-year-old girl with failure to thrive and intense pruritus associated with Alagille syndrome is described. The clinical features of this autosomal dominant disorder are reviewed. This case highlights the importance of recognizing the severe pruritus as a manifestation of the disease. ...

journal_title：Journal of the American Academy of Dermatology

authors： Schwartz R,Rehder K,Parsons DJ,Morrell DS

更新日期：2008-02-01 00:00:00

abstract：:Three clinicopathologic variants of lichen planopilaris are described. The first is characterized clinically by individual keratotic follicular papules and histologically by a lichenoid inflammatory cell infiltrate confined to the follicular epithelium. The second variant consists of erythematous to violaceous plaques...

journal_title：Journal of the American Academy of Dermatology

authors： Matta M,Kibbi AG,Khattar J,Salman SM,Zaynoun ST

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Guselkumab, an interleukin-23 blocker, was superior to adalimumab in treating moderate to severe psoriasis in a phase II trial. OBJECTIVES:We sought to compare efficacy and safety of guselkumab with adalimumab and placebo in patients with psoriasis treated for 1 year. METHODS:Patients were randomized to gu...

journal_title：Journal of the American Academy of Dermatology

authors： Blauvelt A,Papp KA,Griffiths CE,Randazzo B,Wasfi Y,Shen YK,Li S,Kimball AB

更新日期：2017-03-01 00:00:00

abstract：:A patient with acquired immunodeficiency syndrome presented with multiple pruritic papules and nodules over the trunk and extremities. Biopsy specimens from two of these lesions contained granules within abscesses of the papillary dermis. There were numerous gram-positive cocci within the granules. Culture of one lesi...

journal_title：Journal of the American Academy of Dermatology

authors： Patterson JW,Kitces EN,Neafie RC

更新日期：1987-01-01 00:00:00

abstract：:Lipedema is characterized by symmetric lower extremity enlargement secondary to the deposition of fat. Lipedema is not rare, but it is commonly misdiagnosed as lymphedema. We describe a 20-year-old woman with massive lower extremity enlargement that did not respond to compression therapy. Magnetic resonance imaging of...

journal_title：Journal of the American Academy of Dermatology

authors： Fonder MA,Loveless JW,Lazarus GS

更新日期：2007-08-01 00:00:00