Environmental nickel pollution: does it protect against nickel allergy?

abstract：:We describe the clinical and biochemical features of an infant with marked transient porphyrinemia in whom blistering developed while the infant was undergoing phototherapy for severe Rh isoimmunization. The cause of the transient porphyrinemia was likely to be multifactorial--abnormal porphyrin metabolism or accumula...

journal_title：Journal of the American Academy of Dermatology

authors： Mallon E,Wojnarowska F,Hope P,Elder G

更新日期：1995-08-01 00:00:00

abstract：:Removal of Norplant contraceptive implants may be rendered difficult by the size of the capsules and variations in insertion technique. In the standard removal technique, a single transverse incision is made close to and below the distal ends of the capsules, and a mosquito forceps is used for extraction. Described,...

journal_title：Journal of the American Academy of Dermatology

authors： Lam M,Tope WD

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:Recently, an automated robotic hair restoration device was developed and is increasingly being used for hair restoration. OBJECTIVE:We sought to analyze the hair follicles of Korean patients that were harvested by a hair restoration robotic device. METHODS:Data were reviewed from a total of 22 patients who...

journal_title：Journal of the American Academy of Dermatology

authors： Shin JW,Kwon SH,Kim SA,Kim JY,Na JI,Park KC,Huh CH

更新日期：2015-01-01 00:00:00

abstract：BACKGROUND:Overexpression of adhesion molecules in tissues of human neoplasms, including malignant melanoma, has been reported to be clinically relevant, but the predictive value of circulating adhesion molecules for clinical outcome and life expectancy in patients with primary malignant melanoma (PMM) and metastases o...

journal_title：Journal of the American Academy of Dermatology

authors： Schaider H,Rech-Weichselbraun I,Richtig E,Seidl H,Soyer HP,Smolle J,Kerl H

更新日期：1997-02-01 00:00:00

abstract：:A 7-week-old male infant with a seizure disorder and an extensive sebaceous nevus of the scalp was examined. Computerized axial tomography (CAT) scan identified an intracerebral mass which proved to be a hamartomatous malofrmation fo the brain. The association of intracranial masses with sebaceous nevi should be recog...

journal_title：Journal of the American Academy of Dermatology

authors： Moskowitz R,Honig PJ

更新日期：1982-06-01 00:00:00

abstract：BACKGROUND:Allergic contact dermatitis (ACD) to optical brighteners and enzymes in laundry detergents was the focus of numerous reports in the early 1970s. Subsequently, there has been little published on the incidence of allergic reactions to chemicals in laundry detergents. Nonetheless, consumers and physicians conti...

journal_title：Journal of the American Academy of Dermatology

authors： Belsito DV,Fransway AF,Fowler JF Jr,Sherertz EF,Maibach HI,Mark JG Jr,Mathias CG,Rietschel RL,Storrs FJ,Nethercott JR

更新日期：2002-02-01 00:00:00

abstract：BACKGROUND:Although cyclosporine has been found to be effective therapy for severe psoriasis, only limited data exist about efficacy and safety during long-term treatment with a low-dose regimen. Furthermore, little is known about the course of psoriasis after drug withdrawal. OBJECTIVE:Our purpose was to assess the r...

journal_title：Journal of the American Academy of Dermatology

authors： Mrowietz U,Färber L,Henneicke-von Zepelin HH,Bachmann H,Welzel D,Christophers E

更新日期：1995-09-01 00:00:00

abstract：BACKGROUND:The autoantibody-mediated disease in fogo selvagem (FS) is aggravated by sunlight exposure. OBJECTIVE:The aim of this study was to test whether UVB exposure of uninvolved skin of patients with FS (n = 21) enhances epidermal acantholysis and in vivo binding of FS autoantibodies as compared with a control gro...

journal_title：Journal of the American Academy of Dermatology

authors： Reis VM,Toledo RP,Lopez A,Diaz LA,Martins JE

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:The adult burden of atopic dermatitis (AD) is poorly characterized. OBJECTIVE:We sought to characterize AD burden in adults with moderate to severe disease from the patient's perspective. METHODS:Patient-reported outcomes collected at screening in a phase 2b clinical trial of dupilumab included pruritus nu...

journal_title：Journal of the American Academy of Dermatology

authors： Simpson EL,Bieber T,Eckert L,Wu R,Ardeleanu M,Graham NM,Pirozzi G,Mastey V

更新日期：2016-03-01 00:00:00

abstract：:An unusual American epidemic consisting of twenty cases of granuloma inguinale is chronicled. Evidence from this series supports the venereal transmission of the disorder. Trimethoprim/sulfamethoxazole proved to be a safe and effective therapy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Rosen T,Tschen JA,Ramsdell W,Moore J,Markham B

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:Botulinum toxin type A (BTX-A) is widely used for facial esthetics but is incompletely studied. OBJECTIVE:This study was conducted to evaluate the efficacy and safety of BTX-A treatment of glabellar lines. METHODS:Patients with moderate to severe glabellar lines at maximum frown received intramuscular inje...

journal_title：Journal of the American Academy of Dermatology

authors： Carruthers JA,Lowe NJ,Menter MA,Gibson J,Nordquist M,Mordaunt J,Walker P,Eadie N,BOTOX Glabellar Lines I Study Group.

更新日期：2002-06-01 00:00:00

abstract：:The occurrence of Langerhans cell histiocytosis (LCH) and malignancy in the same patient is rare. When LCH occurs concomitantly with acute leukemia, distinct temporal patterns often exist; acute myelogenous leukemia (AML) typically succeeds LCH, whereas acute lymphocytic leukemia (ALL) usually precedes it. We report a...

journal_title：Journal of the American Academy of Dermatology

authors： Chiles LR,Christian MM,McCoy DK,Hawkins HK,Yen AH,Raimer SS

更新日期：2001-12-01 00:00:00

abstract：:Oral retinoids are among the drugs of choice for pustular and erythrodermic psoriasis. In addition, retinoids are effective in combination with other topical and systemic agents for the treatment of plaque-type psoriasis. Acitretin, the active retinoid metabolite, has replaced etretinate in retinoid therapy of psorias...

journal_title：Journal of the American Academy of Dermatology

authors： Katz HI,Waalen J,Leach EE

更新日期：1999-09-01 00:00:00

abstract：BACKGROUND:Incomplete Mohs micrographic surgery (MMS) is the cessation of MMS while the tumor margins are known to be still positive. OBJECTIVE:Our purpose was to examine the factors behind unplanned incomplete MMS and to identify means of avoiding and managing this situation when it arises. METHODS:We performed a re...

journal_title：Journal of the American Academy of Dermatology

authors： Madani S,Huilgol SC,Carruthers A

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:Previous studies have demonstrated that patients with psoriasis may have an increased risk of a variety of noncutaneous diseases, including arterial and venous occlusive diseases. Changes in plasma lipid and lipoprotein composition in patients with psoriasis may be the reason for the increased risk of athero...

journal_title：Journal of the American Academy of Dermatology

authors： Seçkin D,Tokgözoğlu L,Akkaya S

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:Hydroxychloroquine is widely used for the treatment of cutaneous lupus erythematosus (CLE). Although new recommendations exist for hydroxychloroquine dosing, there is still uncertainty about the dosage that will elicit a satisfactory response in CLE while limiting adverse effects, specifically retinopathy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Shipman WD,Vernice NA,Demetres M,Jorizzo JL

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Lymphomatoid papulosis (LyP) is a cyclic papulonodular eruption that is clinically benign and histologically malignant. Association with hematologic neoplasias has been reported in 5% to 20% of all cases. OBJECTIVE:We sought to review the clinical and histopathologic features of LyP in pediatric patients. ...

journal_title：Journal of the American Academy of Dermatology

authors： de Souza A,Camilleri MJ,Wada DA,Appert DL,Gibson LE,el-Azhary RA

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:The mature psoriatic lesion does not necessarily demonstrate changes relevant to early phases of the lesion. OBJECTIVE:In a model for relapsing psoriasis we examined the epidermal phenotype by means of a panel of immunohistochemical parameters: keratins 14 and 16, epidermal growth factor receptor (EGFR), Ki...

journal_title：Journal of the American Academy of Dermatology

authors： Castelijns FA,Gerritsen MJ,van Vlijmen-Willems IM,van Erp PE,van de Kerkhof PC

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:Preventing fetal exposure to isotretinoin is an important public health goal. Since approval of isotretinoin (1982), the Food and Drug Administration has implemented several unsuccessful risk management programs aimed at preventing fetal exposure. The Kaiser Permanente isotretinoin risk management program in...

journal_title：Journal of the American Academy of Dermatology

authors： Cheetham TC,Wagner RA,Chiu G,Day JM,Yoshinaga MA,Wong L

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Psoralen plus ultraviolet A (PUVA) for the treatment of psoriasis has never been evaluated using the Psoriasis Area Severity Index (PASI) in a randomized, double-blind, placebo-controlled trial. The lack of such data limits our capacity to estimate PUVA's efficacy relative to other treatment options that are...

journal_title：Journal of the American Academy of Dermatology

authors： Sivanesan SP,Gattu S,Hong J,Chavez-Frazier A,Bandow GD,Malick F,Kricorian G,Koo J

更新日期：2009-11-01 00:00:00

abstract：:The growing investigation and use of epidermal growth factor receptor (EGFR) inhibitors in anticancer therapy has been motivated by their specificity for EGFR, which improves their ability to target cancer cells and enhances their safety profile compared with many other conventional chemotherapeutic agents. However, t...

journal_title：Journal of the American Academy of Dermatology

authors： Hu JC,Sadeghi P,Pinter-Brown LC,Yashar S,Chiu MW

更新日期：2007-02-01 00:00:00

abstract：:A 9-year-old girl with systemic lupus erythematosus developed bullous eruption. Histopathologic examination showed subepidermal blistering and immunoglobulins (IgG, IgM, IgA) and complement components (C1q, C3) deposited linearly at the basement membrane zone. IgG in this patient's serum bound to the dermal side of 1 ...

journal_title：Journal of the American Academy of Dermatology

authors： Shirahama S,Furukawa F,Yagi H,Tanaka T,Hashimoto T,Takigawa M

更新日期：1998-05-01 00:00:00

abstract：:Hydrogen peroxide (H2O2) is an endogenous reactive oxygen species that contributes to oxidative stress directly as a molecular oxidant and indirectly through free radical generation. Topically applied 1% to 45% H2O2 can be used for a range of clinical purposes, which will be reviewed here in addition to its safety. In...

journal_title：Journal of the American Academy of Dermatology

authors： Murphy EC,Friedman AJ

更新日期：2019-12-01 00:00:00

abstract：BACKGROUND:The focal facial dermal dysplasias (FFDD) are a genetically heterogeneous group of disorders characterized by congenital bilateral scarlike facial lesions, with or without associated facial anomalies. The cases have been reported under various names; thus the nosology is confusing and unclear. OBJECTIVE:Our...

journal_title：Journal of the American Academy of Dermatology

authors： Kowalski DC,Fenske NA

更新日期：1992-10-01 00:00:00

abstract：:Primary hyperoxaluria encompasses 3 rare genetic disorders of glyoxylate metabolism characterized by excessive urinary excretion of oxalic acid, resulting in oxalosis. Patients typically have recurrent calcium oxalate nephrolithiasis and nephrocalcinosis, leading to chronic renal failure and death from uremia. Oxalate...

journal_title：Journal of the American Academy of Dermatology

authors： Marconi V,Mofid MZ,McCall C,Eckman I,Nousari HC

更新日期：2002-02-01 00:00:00

abstract：:Thyroid autoimmunity has been increasingly reported to be associated with chronic urticaria and angioedema. The administration of thyroid hormone may alleviate chronic urticaria and/or angioedema in selected patients. This review focuses on the association of thyroid autoimmunity with chronic urticaria and/or angioede...

journal_title：Journal of the American Academy of Dermatology

authors： Heymann WR

更新日期：1999-02-01 00:00:00

abstract：:Squamous cell carcinoma of the penis is almost exclusively a lesion of uncircumcised older men. It represents about 1% of cancers in men in the United States and 11% to 12% of all cancers in men in countries where circumcision is not routinely practiced. Verrucous carcinoma is an uncommon variant that accounts for onl...

journal_title：Journal of the American Academy of Dermatology

authors： Kanik AB,Lee J,Wax F,Bhawan J

更新日期：1997-08-01 00:00:00

abstract：BACKGROUND:ESPRIT is an ongoing, 10-year, observational registry, evaluating long-term safety and effectiveness of adalimumab treatment in routine clinical practice for patients with moderate to severe, chronic plaque psoriasis. OBJECTIVES:Initial 5-year results are reported. METHODS:Two populations were analyzed: th...

journal_title：Journal of the American Academy of Dermatology

authors： Menter A,Thaçi D,Papp KA,Wu JJ,Bereswill M,Teixeira HD,Rubant S,Williams DA

更新日期：2015-09-01 00:00:00

abstract：:A 7.3-year prospective study of 1,380 patients with psoriasis who were treated with oral methoxsalen (8-methoxypsoralen) and ultraviolet A photochemotherapy (PUVA) revealed that patients who continued on PUVA therapy used inpatient hospital treatment less than one fourth as often as those who had discontinued treatmen...

journal_title：Journal of the American Academy of Dermatology

authors： Stern RS

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Tissue-destructive and more selective cytotoxic therapies are the main methods used to treat actinic cheilitis. A topical immune stimulant, 5% imiquimod cream, has recently been used for treatment of cutaneous epithelial malignancies including squamous cell carcinoma in situ and basal cell carcinoma. OBJECT...

journal_title：Journal of the American Academy of Dermatology

authors： Smith KJ,Germain M,Yeager J,Skelton H

更新日期：2002-10-01 00:00:00