当前位置： SCI文献检索 > JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY期刊下所有文献 > Frequency, levels, and significance of blood eosinophilia in systemic sclerosis, localized scleroderma, and eosinophilic fasciitis.

Frequency, levels, and significance of blood eosinophilia in systemic sclerosis, localized scleroderma, and eosinophilic fasciitis.

Abstract：

:Blood eosinophilia is a common feature of eosinophilic fasciitis and is variably reported in systemic sclerosis and localized scleroderma. Since these diseases share cutaneous fibrosis as the final outcome and have other clinical and pathologic features that are difficult to differentiate, the presence of blood eosinophilia may be a further source of confusion. In this study, we examined the frequency and level of blood eosinophilia in 715 patients with systemic sclerosis, 72 patients with localized scleroderma, and 22 patients with clinically active eosinophilic fasciitis. When defined as greater than 400 cells/mm3, eosinophilia was present in 7% of patients with systemic sclerosis, 31% of patients with localized scleroderma, and 83% of patients with eosinophilic fasciitis. Greater than 1000 eosinophils/mm3 were present less frequently in systemic sclerosis (1%) and localized scleroderma (8%) than in eosinophilic fasciitis (61%). No difference in the frequency of eosinophilia was present in patients with the limited cutaneous CREST syndrome or the diffuse cutaneous variety of systemic sclerosis, and in these patients the presence of eosinophilia did not correlate with the extent of cutaneous or internal organ involvement or with other laboratory abnormalities. Among patients with localized scleroderma, eosinophilia was more common in those with linear scleroderma and generalized morphea than in those with morphea, and both the frequency and level of eosinophilia were greater in individuals with clinically active disease (p less than 0.02). Eosinophilia was a persistent feature in untreated patients with active eosinophilic fasciitis, even up to 30 months of disease duration.

journal_name

J Am Acad Dermatol

journal_title

Journal of the American Academy of Dermatology

authors

Falanga V,Medsger TA Jr

doi

10.1016/s0190-9622(87)70251-5

subject

Has Abstract

pub_date

1987-10-01 00:00:00

pages

648-56

issue

4

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(87)70251-5

journal_volume

17

pub_type

杂志文章

相关文献

JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY文献大全
  • An annular plaque due to Mycobacterium haemophilum infection in a patient with AIDS.

    abstract：:Infections with mycobacteria are of importance in the differential diagnosis of skin lesions in immunocompromised patients. We report the case of a human immunodeficency virus (HIV)-infected patient who presented with an annular plaque as cutaneous manifestation of Mycobacterium haemophilum. Improvement of the immunol...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1067/mjd.2000.102455

    authors： Friedli A,Krischer J,Hirschel B,Saurat JH,Pechère M

    更新日期：2000-11-01 00:00:00

  • Dermatoscopic characteristics of acrochordon-like basal cell carcinomas in Gorlin-Goltz syndrome.

    abstract：BACKGROUND:Gorlin-Goltz syndrome (GGS) is an autosomal-dominant disease characterized by the early onset of multiple basal cell carcinomas (BCCs), among other findings. Clinically, the BCCs may appear as soft pedunculated neoplasms that can be mistaken for true acrochordons. OBJECTIVE:We sought to describe the dermato...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/j.jaad.2008.11.023

    authors： Feito-Rodríguez M,Sendagorta-Cudós E,Moratinos-Martínez M,González-Beato MJ,de Lucas-Laguna R,Pizarro A

    更新日期：2009-05-01 00:00:00

  • Cutaneous malacoplakia: a report of two cases and review of the literature.

    abstract：:Malacoplakia, an inflammatory disease characterized by accumulations of phagocytic macrophages, occurs primarily in immunocompromised individuals. Cutaneous involvement is rare. Two men, each with a renal allograft, had expanding nodules on the temple and perianal area (case 1) and perianal, inguinal, and scrotal skin...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章,评审

    doi：10.1016/s0190-9622(07)80002-8

    authors： Lowitt MH,Kariniemi AL,Niemi KM,Kao GF

    更新日期：1996-02-01 00:00:00

  • Interclinician agreement on the recognition of selected gross morphologic features of pigmented lesions. Studies of melanocytic nevi V.

    abstract：BACKGROUND:Since the late 1970s clinical criteria for dysplastic melanocytic nevi (DMN) have been proposed and discussed. However, to our knowledge, no rigorous quantitative evaluation of the ability of examiners to agree on the gross morphologic features ascribed to DMN or atypical melanocytic lesions in general has b...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/0190-9622(92)70023-9

    authors： Barnhill RL,Roush GC,Ernstoff MS,Kirkwood JM

    更新日期：1992-02-01 00:00:00

  • Classic Kaposi's sarcoma: T-lymphocyte subsets, T4/T8 ratio, and NK cell activity.

    abstract：:Lymphocyte function as expressed by T-lymphocyte subsets and natural killer cell activity was evaluated in a group of Israeli patients with classic Kaposi's sarcoma. T-cell subsets were examined in 28 patients, 14 with lesions limited to the lower extremities and 14 with diffuse cutaneous or systemic involvement. CD4 ...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/0190-9622(91)70149-v

    authors： Friedman-Birnbaum R,Weltfriend S,Pollack S

    更新日期：1991-06-01 00:00:00

  • Immunopathologic study of lichenoid skin diseases: correlation between HLA-DR-positive keratinocytes or Langerhans cells and epidermotropic T cells.

    abstract：:Skin biopsy specimens from 24 patients with different lichenoid skin diseases that had been proved histologically were studied immunohistologically. Marked differences were noted in the number of OKT6+/S100+ Langerhans cells within the epidermis and dermis in the lesional skin between lichen planus (and its related di...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/s0190-9622(88)70011-0

    authors： Shiohara T,Moriya N,Tanaka Y,Arai Y,Hayakawa J,Chiba M,Nagashima M

    更新日期：1988-01-01 00:00:00

  • Propranolol treatment of infantile hemangioma (IH) is not associated with developmental risk or growth impairment at age 4 years.

    abstract：BACKGROUND:Long-term adverse effects of propranolol treatment for infantile hemangioma (IH) in young children have been suggested. OBJECTIVE:To compare growth and development in children treated with propranolol for IH with nontreated healthy controls. METHODS:Eighty two (73%) children with IH aged 43 to 51 months tr...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/j.jaad.2016.02.1218

    authors： Moyakine AV,Kerstjens JM,Spillekom-van Koulil S,van der Vleuten CJ

    更新日期：2016-07-01 00:00:00

  • Simplified fixative medium for direct immunofluorescence in skin biopsies.

    abstract：:The main limitation for the use of direct immunofluorescence in skin biopsies was the necessity for frozen tissue. In 1973 Michel et al reported use of a liquid fixative, consisting of ammonium sulfate, N-ethyl-maleimide, magnesium sulfate, and potassium citrate, for handling skin biopsy specimens. The present study i...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/s0190-9622(85)70103-x

    authors： Niedecken HW,Lange CE

    更新日期：1985-05-01 00:00:00

  • Acanthosis nigricans: a cutaneous marker of tissue resistance to insulin.

    abstract：:Tissue resistance to insulin is a major feature underlying the development of acanthosis nigricans in many patients. We report two unusual cases of acanthosis nigricans with contrasting forms of insulin resistance and propose an algorithm for the evaluation of patients with acanthosis nigricans. Further, we present a ...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章,评审

    doi：10.1016/s0190-9622(89)70208-5

    authors： Rendon MI,Cruz PD Jr,Sontheimer RD,Bergstresser PR

    更新日期：1989-09-01 00:00:00

  • Basal cell carcinoma and squamous cell carcinoma growth rates and determinants of size in community patients.

    abstract：BACKGROUND:Cutaneous basal cell carcinomas (BCCs) and squamous cell carcinomas (SCCs) have poorer outcomes if treated when large. OBJECTIVE:We sought to estimate the growth rate of BCCs and SCCs and examine the relationship of personal, pathway, and cancer factors with cancer size (diameter). METHODS:We surveyed pati...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/j.jaad.2013.11.009

    authors： Kricker A,Armstrong B,Hansen V,Watson A,Singh-Khaira G,Lecathelinais C,Goumas C,Girgis A

    更新日期：2014-03-01 00:00:00

  • Chemexfoliation--indications and cautions.

    abstract：:Chemexfoliation (chemical peeling) is being used to obtain both therapeutic (e.g., actinic keratoses) and cosmetic (e.g., removal of fine facial rhytides) benefits. Phenol, one of the most widely used agents for inducing cutaneous exfoliation, may induce cardiac arrhythmias and is toxic to the liver and kidneys. Trich...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/s0190-9622(87)70181-9

    authors： Lober CW

    更新日期：1987-07-01 00:00:00

  • Epidemiology and treatment of angiolymphoid hyperplasia with eosinophilia (ALHE): A systematic review.

    abstract：BACKGROUND:Current knowledge of angiolymphoid hyperplasia with eosinophilia (ALHE) derives from retrospective reports and case series, leading to a nonevidence-based treatment approach. OBJECTIVE:We sought to systematically review the literature relating to cutaneous ALHE to estimate its epidemiology and treatment out...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jaad.2015.10.011

    authors： Adler BL,Krausz AE,Minuti A,Silverberg JI,Lev-Tov H

    更新日期：2016-03-01 00:00:00

  • Use of tumor necrosis factor (TNF) inhibitors in patients with HIV/AIDS.

    abstract：:Patients with HIV and AIDS are living longer because of advancements in antiretroviral therapy. These patients are often susceptible to debilitating inflammatory disorders that are refractory to standard treatment. We discuss the relationship of tumor necrosis factor-alpha and HIV and then review 27 published cases of...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章,评审

    doi：10.1016/j.jaad.2015.11.043

    authors： Gallitano SM,McDermott L,Brar K,Lowenstein E

    更新日期：2016-05-01 00:00:00

  • A randomized, double-blind, placebo-controlled, phase I study of MEDI-545, an anti-interferon-alfa monoclonal antibody, in subjects with chronic psoriasis.

    abstract：BACKGROUND:Interferon-alfa (IFN-alpha) has been implicated in the pathogenesis of psoriasis. OBJECTIVE:To evaluate the safety profile of MEDI-545, a fully human anti-IFN-alpha monoclonal antibody and to explore its effect on the involvement of type I IFN-alpha activity in the maintenance of established plaque psoriasi...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章,随机对照试验

    doi：10.1016/j.jaad.2009.05.042

    authors： Bissonnette R,Papp K,Maari C,Yao Y,Robbie G,White WI,Le C,White B

    更新日期：2010-03-01 00:00:00

  • Occurrence of subacute cutaneous lupus erythematosus after treatment with fluorouracil and capecitabine.

    abstract：:Capecitabine, an oral fluoropyrimidine and 5-fluorouracil (FU) prodrug recently approved for the treatment of metastatic colon and breast cancer, is currently under investigation in patients with gastric cancer. It has the advantage of oral administration, and good tolerability with its activity being comparable with ...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/j.jaad.2007.06.040

    authors： Weger W,Kränke B,Gerger A,Salmhofer W,Aberer E

    更新日期：2008-08-01 00:00:00

  • Subcutaneous myospherulosis.

    abstract：:Myospherulosis is an uncommon subcutaneous disorder believed initially to be caused by an endosporulating fungus. Recently investigators have disproved an infectious cause and have shown that the disease represents an alteration in red blood cells, usually produced by petrolatum or lanolin, with an accompanying foreig...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章,评审

    doi：10.1016/s0190-9622(89)80045-3

    authors： Waldman JS,Barr RJ,Espinoza FP,Simmons GE

    更新日期：1989-08-01 00:00:00

  • Response to topical corticosteroid monotherapy in mycosis fungoides.

    abstract：BACKGROUND:Topical corticosteroids alone or in combination with other therapies are widely used to treat mycosis fungoides (MF), but data on response rates to their use as monotherapy in MF are limited. OBJECTIVE:To evaluate the efficacy of topical corticosteroid monotherapy in MF; compare sex, age, stage distribution...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/j.jaad.2020.05.043

    authors： Kartan S,Shalabi D,O'Donnell M,Alpdogan SO,Sahu J,Shi W,Porcu P,Cha J,Nikbakht N

    更新日期：2020-05-16 00:00:00

  • The classification of inherited epidermolysis bullosa (EB): Report of the Third International Consensus Meeting on Diagnosis and Classification of EB.

    abstract：BACKGROUND:Since publication in 2000 of the Second International Consensus Report on Diagnosis and Classification of Epidermolysis Bullosa, many advances have been made to our understanding of this group of diseases, both clinically and molecularly. At the same time, new epidermolysis bullosa (EB) subtypes have been de...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 共识发展会议,杂志文章

    doi：10.1016/j.jaad.2008.02.004

    authors： Fine JD,Eady RA,Bauer EA,Bauer JW,Bruckner-Tuderman L,Heagerty A,Hintner H,Hovnanian A,Jonkman MF,Leigh I,McGrath JA,Mellerio JE,Murrell DF,Shimizu H,Uitto J,Vahlquist A,Woodley D,Zambruno G

    更新日期：2008-06-01 00:00:00

  • Sclerotherapy for the permanent eradication of varicose veins: theoretical and practical considerations.

    abstract：:Although sclerotherapy is an established procedure to treat ectatic veins, a wide disparity remains in the reported rates of success, especially for larger varicose veins. This article reviews the venous anatomy of the lower extremity and outlines the indications for sclerotherapy. The historical basis for treatment t...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章,评审

    doi：10.1016/s0190-9622(98)70506-7

    authors： Green D

    更新日期：1998-03-01 00:00:00

  • Body dysmorphic disorder symptoms among patients with acne vulgaris.

    abstract：BACKGROUND:Acne is one of the most common concerns of patients with body dysmorphic disorder (BDD), a psychiatric condition defined as a preoccupation with a slight or imagined defect in appearance that causes significant disruption in daily functioning. OBJECTIVE:We sought to screen for BDD symptoms among patients wi...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/j.jaad.2007.03.030

    authors： Bowe WP,Leyden JJ,Crerand CE,Sarwer DB,Margolis DJ

    更新日期：2007-08-01 00:00:00

  • Parakeratosis.

    abstract：:The diagnostic value of parakeratosis is reviewed, with special emphasis on associated inflammatory tissue reaction patterns and the geometric pattern of the scale. Parakeratosis may also occur in disorders not primarily inflammatory in nature and those associations are addressed. Topics are divided into 6 categories:...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章,评审

    doi：10.1016/s0190-9622(03)02801-9

    authors： Brady SP

    更新日期：2004-01-01 00:00:00

  • Giant acquired digital fibrokeratoma.

    abstract：:We describe a 33-year-old patient with a giant skin tumor on her right big toe. The tumor was characterized by unusual clinical manifestations including huge size and papillomatous surface. Chronic long-standing irritation as a result of aerobic exercise may have been involved in the development of giant fibrokeratoma...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1067/mjd.2003.153

    authors： Kakurai M,Yamada T,Kiyosawa T,Ohtsuki M,Nakagawa H

    更新日期：2003-05-01 00:00:00

  • Actinic prurigo among the Chimila Indians in Colombia: HLA studies.

    abstract：:The Chimila, a Colombian Amerindian group that lives at a low altitude, have a high incidence of actinic prurigo. We present the human lymphocyte antigen (HLA) findings of 43 Chimilas with the disease and of 62 control subjects and show an association of actinic prurigo with the Cw4 antigen. ...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/0190-9622(90)70150-g

    authors： Bernal JE,Duran de Rueda MM,Ordonez CP,Duran C,de Brigard D

    更新日期：1990-06-01 00:00:00

  • Synthetic membranes and cultured keratinocyte grafts.

    abstract：:Significant progress has been made in skin replacement options in the past several decades. Although initially various materials have been used mainly for burn coverage, their application to dermatologic practice has increased significantly. We review the research, progress, and other aspects of wound coverage with sy...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章,评审

    doi：10.1016/0190-9622(90)70279-q

    authors： Límová M,Grekin RC

    更新日期：1990-10-01 00:00:00

  • Histologic and clinical cross-sectional study of chronic hair loss in patients with cutaneous chronic graft-versus-host disease.

    abstract：BACKGROUND:While scalp alopecia represents a distinctive feature of chronic graft-versus-host disease (cGVHD), little is known about the clinical and histologic presentation of hair loss. OBJECTIVES:We sought to classify the clinical presentations and histologic findings of chronic hair loss in patients with cutaneous...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/j.jaad.2019.03.031

    authors： Marks DH,Naftulin JS,Penzi LR,Manatis-Lornell A,Yasuda MR,Chapman CM,Rao SR,Saavedra A,Senna MM

    更新日期：2019-11-01 00:00:00

  • Effect of sequential applications of topical tacrolimus and topical corticosteroids in the treatment of pediatric atopic dermatitis: an open-label pilot study.

    abstract：BACKGROUND:The efficacy of combination therapy with topical corticosteroids and tacrolimus in the treatment of atopic dermatitis remains to be established. OBJECTIVE:Our aim was to determine whether a regimen of sequential application of topical corticosteroids and topical tacrolimus is effective in the treatment of p...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 临床试验,杂志文章

    doi：10.1016/j.jaad.2008.09.034

    authors： Kubota Y,Yoneda K,Nakai K,Katsuura J,Moriue T,Matsuoka Y,Miyamoto I,Ohya Y

    更新日期：2009-02-01 00:00:00

  • Concomitant administration of vitamin E does not change the side effects of isotretinoin as used in acne vulgaris: a randomized trial.

    abstract：BACKGROUND:Isotretinoin treatment is frequently associated with reversible, dose-related side effects. Recent studies claimed that combining vitamin E with high-dose isotretinoin ameliorated isotretinoin-induced side effects. OBJECTIVE:The purpose of this double-blind, randomized study was to determine the effects of ...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 临床试验,杂志文章,多中心研究,随机对照试验

    doi：10.1067/mjd.2000.110391

    authors： Strauss JS,Gottlieb AB,Jones T,Koo JY,Leyden JJ,Lucky A,Pappas AA,McLane J,Leach EE

    更新日期：2000-11-01 00:00:00

  • Herpes zoster in children.

    abstract：BACKGROUND:The clinical studies of series of children with herpes zoster (HZ) are rather limited. OBJECTIVE:The purpose of this study was to evaluate the epidemiologic conditions, clinical manifestations, therapy, and outcome of HZ in children. METHODS:Twenty-one patients with HZ have been studied. Five patients who ...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/s0190-9622(98)70076-3

    authors： Kakourou T,Theodoridou M,Mostrou G,Syriopoulou V,Papadogeorgaki H,Constantopoulos A

    更新日期：1998-08-01 00:00:00

  • Cutaneous phaeohyphomycosis due to Cladophialophora bantiana.

    abstract：:We present a case of cutaneous infection due to Cladophialophora bantiana, an agent of phaeohyphomycosis. The patient developed a nodule with pustule formation on the dorsum of the left hand; no trauma was reported. The lesion was successfully treated with itraconazole and surgical excision. Histopathologically, there...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/s0190-9622(99)70487-1

    authors： Patterson JW,Warren NG,Kelly LW

    更新日期：1999-02-01 00:00:00

  • Injection site reactions with the HIV-1 fusion inhibitor enfuvirtide.

    abstract：BACKGROUND:Enfuvirtide is the first of a new class of antiretroviral agents for the treatment of HIV-1 infection, called the fusion inhibitors. The most common type of adverse event associated with enfuvirtide treatment is injection site reactions, occurring in up to 98% of patients. Many of these lesions are symptomat...

    journal_title：Journal of the American Academy of Dermatology

    pub_type： 杂志文章

    doi：10.1016/s0190-9622(03)02099-1

    authors： Ball RA,Kinchelow T,ISR Substudy Group.

    更新日期：2003-11-01 00:00:00