Concomitant administration of vitamin E does not change the side effects of isotretinoin as used in acne vulgaris: a randomized trial.

abstract：:A 72-year-old woman with a large mass on her forehead was found to have primary cutaneous CD30-positive large T-cell lymphoma and was treated with radiation therapy. Five weeks after the completion of radiation therapy, a large, yellow plaque developed on the forehead. Histopathologic examination showed numerous xanth...

journal_title：Journal of the American Academy of Dermatology

authors： Chung HG,Chung YL,Kang JM,Yang WI,Suh CO,Hahn JS,Leea MG

更新日期：2003-02-01 00:00:00

abstract：BACKGROUND:Patients with pemphigus vulgaris (PV) are genetically linked to two alleles of the HLA subgroup, and circulating antibodies were found in first-degree relatives of these patients, thus showing genetic predisposition. OBJECTIVE:Our purpose was to determine the occurrence of circulating true PV-IgG in patient...

journal_title：Journal of the American Academy of Dermatology

authors： Brandsen R,Frusic-Zlotkin M,Lyubimov H,Yunes F,Michel B,Tamir A,Milner Y,Brenner S

更新日期：1997-01-01 00:00:00

abstract：:Lupus erythematosus (LE) is a multisystem disease. Genetic predisposition, altered immunity, hormones, drugs, viruses, and ultraviolet light all may play a role in etiology. A wide range of cutaneous lesions occur, and variants such as subacute cutaneous LE, complement-deficient LE, and neonatal LE have recently been ...

journal_title：Journal of the American Academy of Dermatology

authors： Tuffanelli DL

更新日期：1981-02-01 00:00:00

abstract：BACKGROUND:Junctional nevi are traditionally associated with children and younger patients. We noticed that these lesions are also often found in elderly patients. OBJECTIVE:We sought to determine if junctional nevi are found in all age groups. METHODS:All biopsy reports for junctional nevi for the year 2001 at the P...

journal_title：Journal of the American Academy of Dermatology

authors： Westhafer J,Gildea J,Klepeiss S,Clarke L,Helm K

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:The association of atopic dermatitis (AD) with other allergic diseases has been extensively studied; however, there is a lack of reports focusing on long-term studies of the clinical and allergometric evaluations observed during the course of AD in respect to its evolution and association with allergic respo...

journal_title：Journal of the American Academy of Dermatology

authors： Ricci G,Patrizi A,Baldi E,Menna G,Tabanelli M,Masi M

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Cutaneous leishmaniasis (CL) is caused by different species of Leishmania and transmitted by the bite of infected sand flies. It is a health problem in many countries. OBJECTIVE:This study was performed to assess the evidence for the efficacy of different therapeutic modalities for acute Old World CL, which...

journal_title：Journal of the American Academy of Dermatology

authors： Khatami A,Firooz A,Gorouhi F,Dowlati Y

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Appropriate primary end points in randomized controlled trials (RCTs) improve the quality of the measurement and enable comparison of the findings with those of other trials. OBJECTIVE:To assess the quality of reporting primary end points in RCTs recently published in dermatology journals. METHODS:We ident...

journal_title：Journal of the American Academy of Dermatology

authors： Kim DY,Oh S,Yoon HS

更新日期：2020-04-22 00:00:00

abstract：BACKGROUND:Basal cell carcinomas (BCCs) with high-risk features are preferably treated by Mohs micrographic surgery. Studies have shown clinicopathologic characteristics that may predict more stages required for clearance. However, few studies have correlated such factors with the number of millimeters removed per stag...

journal_title：Journal of the American Academy of Dermatology

authors： Cerci FB,Kubo EM,Werner B,Tolkachjov SN

更新日期：2020-08-01 00:00:00

abstract：BACKGROUND:Little is known about how individuals with a predisposition for rosacea appear in childhood. This retrospective, matched control, longitudinal study examined the relationship between childhood stye and adult rosacea. METHODS:The records of the Rochester Epidemiology Project were examined to identify patient...

journal_title：Journal of the American Academy of Dermatology

authors： Bamford JT,Gessert CE,Renier CM,Jackson MM,Laabs SB,Dahl MV,Rogers RS 3rd

更新日期：2006-12-01 00:00:00

abstract：:We present the case of two patients with an unusual form of discoid lupus erythematosus that was confined almost exclusively to the palms and soles. In both patients this form of discoid lupus erythematosus did not respond to conventional therapies, which included topical steroids, intralesional steroids, prednisone, ...

journal_title：Journal of the American Academy of Dermatology

authors： Ashinoff R,Werth VP,Franks AG Jr

更新日期：1988-11-01 00:00:00

abstract：:The psychosocial impact of infection with human immunodeficiency virus (HIV) can be viewed from three perspectives: (1) the issues focused by acquired immunodeficiency syndrome (AIDS), (2) the persons affected, and (3) the emotions encountered. Among the many issues faced by AIDS patients, their families, and their ca...

journal_title：Journal of the American Academy of Dermatology

authors： Cline DJ

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:There is a lack of data on outcomes of management of pemphigus in children. OBJECTIVE:We sought to evaluate rituximab treatment in childhood and juvenile pemphigus. METHOD:All cases of pemphigus treated with rituximab in patients younger than 18 years were included. Clinical and epidemiologic data and deta...

journal_title：Journal of the American Academy of Dermatology

authors： Vinay K,Kanwar AJ,Sawatkar GU,Dogra S,Ishii N,Hashimoto T

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Interferon-alfa (IFN-alpha) has been implicated in the pathogenesis of psoriasis. OBJECTIVE:To evaluate the safety profile of MEDI-545, a fully human anti-IFN-alpha monoclonal antibody and to explore its effect on the involvement of type I IFN-alpha activity in the maintenance of established plaque psoriasi...

journal_title：Journal of the American Academy of Dermatology

authors： Bissonnette R,Papp K,Maari C,Yao Y,Robbie G,White WI,Le C,White B

更新日期：2010-03-01 00:00:00

abstract：:Forty-two adults with psoriasis vulgaris were treated total body thrice weekly with both ultraviolet B (UVB) and psoralens and ultraviolet A (PUVA) with the use of protocols shown to be effective with either treatment alone. Patients previously difficult to manage with either UVB or PUVA and at least 25% psoriasis wer...

journal_title：Journal of the American Academy of Dermatology

authors： Momtaz-T K,Parrish JA

更新日期：1984-03-01 00:00:00

abstract：:A 52-year-old man with a history of melanoma presented to the emergency department with a massive intracranial hemorrhage. The patient deteriorated rapidly and was being considered as a potential organ donor. Three years before presentation, the patient had undergone wide excision of a 3.75-mm melanoma from his back w...

journal_title：Journal of the American Academy of Dermatology

authors： Cotter MA,Tristani-Firouzi P

更新日期：2006-06-01 00:00:00

abstract：BACKGROUND:In recent years there has been an increasing focus on human subject protection and on documentation of ethical review in published clinical research. The JAAD clearly states in its instructions to authors, which adhere to the guidelines set forth by the International Committee of Medical Journal Editors, "st...

journal_title：Journal of the American Academy of Dermatology

authors： Perkins AC,Choi JM,Kimball AB

更新日期：2007-02-01 00:00:00

abstract：:We report two cases of primary cutaneous mucormycosis in immunocompromised patients. Although their clinical presentation showed nonspecific necrotic ulcers, the histopathologic features were diagnostic. In both cases, broad, branching, nonseptate hyphae were found in the dermis and subcutaneous tissue. In one case th...

journal_title：Journal of the American Academy of Dermatology

authors： Umbert IJ,Su WP

更新日期：1989-12-01 00:00:00

abstract：BACKGROUND:The tumor necrosis factor (TNF) inhibitor etanercept has been demonstrated to be safe and effective for treating chronic plaque psoriasis in 3 clinical trials. OBJECTIVES:To refine efficacy results for etanercept on the basis of a larger population size through the integration of the 3 studies, and to deter...

journal_title：Journal of the American Academy of Dermatology

authors： Gordon K,Korman N,Frankel E,Wang H,Jahreis A,Zitnik R,Chang T

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Dermatomyositis (DM) is a multisystem autoimmune disease, in which serologic evidence of immune responses to disease-specific antigenic targets is found in approximately 50% to 70% of patients. Recently, melanoma differentiation-associated gene 5 (MDA5) has been identified as a DM-specific autoantigen that a...

journal_title：Journal of the American Academy of Dermatology

authors： Fiorentino D,Chung L,Zwerner J,Rosen A,Casciola-Rosen L

更新日期：2011-07-01 00:00:00

abstract：BACKGROUND:Detecting a more advanced stage of the primary melanoma after wide local excision and reconstruction can complicate patient counseling about prognosis, management of surgical margins, and indications for sentinel lymph node biopsy. OBJECTIVE:To identify the frequency of and risk factors associated with upst...

journal_title：Journal of the American Academy of Dermatology

authors： Etzkorn JR,Sharkey JM,Grunyk JW,Shin TM,Sobanko JF,Miller CJ

更新日期：2017-08-01 00:00:00

abstract：BACKGROUND:Orthopedic surgical procedures involving the foot and ankle are associated with high rates of infection. The optimal method of preparing the skin and nails for foot and ankle surgery remains unknown. OBJECTIVE:This study was conducted to compare the efficacy of 4 different methods of skin and nail preparati...

journal_title：Journal of the American Academy of Dermatology

authors： Becerro de Bengoa Vallejo R,Losa Iglesias ME,Alou Cervera L,Sevillano Fernández D,Prieto Prieto J

更新日期：2009-12-01 00:00:00

abstract：:Keratosis lichenoides chronica is a rare dermatosis of unknown etiology with a wide variety of cutaneous manifestations. We present a 47-year-old male with a history of progressive and recalcitrant hyperkeratotic and warty plaques, mimicking verrucous secondary syphilis both clinically and microscopically. We review t...

journal_title：Journal of the American Academy of Dermatology

authors： Jayaraman AG,Pomerantz D,Robinson-Bostom L

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:The Cutaneous Lupus Disease Area and Severity Index (CLASI) has not been validated using rheumatologist-conducted disease activity and damage assessments, especially cutaneous assessments. Active skin disease and skin damage may have substantial effects on patient-reported outcomes and on body image. OBJECT...

journal_title：Journal of the American Academy of Dermatology

authors： Jolly M,Kazmi N,Mikolaitis RA,Sequeira W,Block JA

更新日期：2013-04-01 00:00:00

abstract：:Recently, low-dose 5-fluorouracil/cisplatin induction concurrent with radiation (chemoradiation) has been reported to be effective for locally advanced squamous cell carcinoma of the otorhinolaryngologic and gynecologic regions. However, to date, this therapeutic option has not been evaluated for squamous cell carcino...

journal_title：Journal of the American Academy of Dermatology

authors： Fujisawa Y,Umebayashi Y,Ichikawa E,Kawachi Y,Otsuka F

更新日期：2006-11-01 00:00:00

abstract：:Two babies were found to have large hemangiomas. Histologically there were many islands of compactly packed mesenchymal cells in the deep dermis and subcutaneous tissue. Electron microscopically there was proliferation of immature endothelial cells and pericytes. Characteristic crystalline lamellae were in the endothe...

journal_title：Journal of the American Academy of Dermatology

authors： Kumakiri M,Muramoto F,Tsukinaga I,Yoshida T,Ohura T,Miura Y

更新日期：1983-01-01 00:00:00

abstract：:Sixty patients were treated for tinea pedis with 2% topical ketoconazole cream either once or twice daily. All diagnoses were confirmed mycologically. They were randomly assigned in a double-blind study into three groups on the basis of their clinical lesions, that is, vesicular pedis, interdigital pedis, and hyperker...

journal_title：Journal of the American Academy of Dermatology

authors： Greer DL

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:Flushing and erythema are frequent skin symptoms in rosacea. Because their adequate treatment remains a clinical challenge, new treatment options are explored, such as oral β-blockers. OBJECTIVES:To evaluate the efficacy of oral β-blockers for rosacea-associated facial flushing and erythema. METHODS:PubMed...

journal_title：Journal of the American Academy of Dermatology

authors： Logger JGM,Olydam JI,Driessen RJB

更新日期：2020-10-01 00:00:00

abstract：:For an investigation of a possible association between HLA antigens and postmethotrexate liver damage, the A, B, C, and Dr loci of the HLA antigens were determined in thirty-two patients with severe psoriasis who had been treated with methotrexate. There was no association between HLA antigens and increasing severity ...

journal_title：Journal of the American Academy of Dermatology

authors： Pestana A,Halprin KM,Taylor JR,Schiff ER,Esquenazi V,Comerford M,Gomez C

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Few studies have examined patients initially presenting with clinical features of urticarial dermatitis (UD). OBJECTIVE:We sought to examine clinical and laboratory evaluations and final diagnoses of patients with clinical features of UD. METHODS:This was a retrospective review of patients with UD seen at ...

journal_title：Journal of the American Academy of Dermatology

authors： Hannon GR,Wetter DA,Gibson LE

更新日期：2014-02-01 00:00:00

abstract：:Calcinosis cutis is characterized by the deposition of insoluble calcium salts in the skin and subcutaneous tissue. The syndrome is separated into five subtypes: dystrophic calcification, metastatic calcification, idiopathic calcification, iatrogenic calcification, and calciphylaxis. Dystrophic calcification appears a...

journal_title：Journal of the American Academy of Dermatology

authors： Reiter N,El-Shabrawi L,Leinweber B,Berghold A,Aberer E

更新日期：2011-07-01 00:00:00