Predictive value of HLA antigen for methotrexate-induced liver damage in patients with psoriasis.

abstract：:Primary cutaneous CD30 (Ki-1)-positive, large cell lymphomas (LCLs) represent a recently recognized group of cutaneous T-cell lymphomas with a favorable prognosis. The characteristic features of this cutaneous lymphoma are reviewed, differences with primary noncutaneous CD30+ LCLs emphasized, and its relation with oth...

journal_title：Journal of the American Academy of Dermatology

authors： Willemze R,Beljaards RC

更新日期：1993-06-01 00:00:00

abstract：BACKGROUND:Tissue-destructive and more selective cytotoxic therapies are the main methods used to treat actinic cheilitis. A topical immune stimulant, 5% imiquimod cream, has recently been used for treatment of cutaneous epithelial malignancies including squamous cell carcinoma in situ and basal cell carcinoma. OBJECT...

journal_title：Journal of the American Academy of Dermatology

authors： Smith KJ,Germain M,Yeager J,Skelton H

更新日期：2002-10-01 00:00:00

abstract：:Squamous cell carcinoma on sun-damaged skin is a malignant neoplasm that evolves from its inception as squamous cell carcinoma in situ, which is commonly referred to as an actinic keratosis. In this study, we reviewed 1011 squamous cell carcinomas on sun-damaged skin and found that nearly 100% of these lesions contain...

journal_title：Journal of the American Academy of Dermatology

authors： Guenthner ST,Hurwitz RM,Buckel LJ,Gray HR

更新日期：1999-09-01 00:00:00

abstract：:We describe a 48-year-old woman with a 12-year history of porphyria cutanea tarda who showed a remarkable exacerbation of her eruptions accompanied by high serum levels of iron and ferritin at menopause. As iron storage is known to be a triggering factor of porphyria cutanea tarda, the possible role of menstruation as...

journal_title：Journal of the American Academy of Dermatology

authors： Nishioka E,Funasaka Y,Bito T,Ito A,Tani M,Kawara A,Yoon S,Kondo M,Ichihashi M

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:The vulvovaginal gingival syndrome is an uncommon and severe variant of lichen planus characterized by erosions or desquamation of vulval, vaginal, and gingival mucosae with a predilection for scarring and stricture formation. OBJECTIVE:We sought to define the clinical, immunopathologic, and human leukocyte...

journal_title：Journal of the American Academy of Dermatology

authors： Setterfield JF,Neill S,Shirlaw PJ,Theron J,Vaughan R,Escudier M,Challacombe SJ,Black MM

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:After oral intake, 5-methoxypsoralen (5-MOP) is as effective as 8-MOP for PUVA therapy for psoriasis, with a lower incidence of acute cutaneous side effects. OBJECTIVE:We compared bath-water delivery of 5-MOP and 8-MOP for photochemotherapy of psoriasis. METHODS:Twenty-two patients underwent phototesting w...

journal_title：Journal of the American Academy of Dermatology

authors： Calzavara-Pinton PG,Zane C,Carlino A,De Panfilis G

更新日期：1997-06-01 00:00:00

abstract：BACKGROUND:Keratoacanthomas usually occur spontaneously as a single rapidly growing tumor on sun-exposed skin. Multiple keratoacanthomas are rarely seen. Keratoacanthomas may also develop after trauma, laser resurfacing, radiation therapy, and at the donor site after skin grafting. OBJECTIVE:We report 6 cases of kerat...

journal_title：Journal of the American Academy of Dermatology

authors： Goldberg LH,Silapunt S,Beyrau KK,Peterson SR,Friedman PM,Alam M

更新日期：2004-05-01 00:00:00

abstract：:A patient with a 10-year history of an acquired, scarring bullous eruption localized to the anterior surfaces of the lower extremities is described. Clinical, histologic, and electron microscopic features of an acquired form of epidermolysis bullosa are shown to occur in the absence of immune deposits, a finding not p...

journal_title：Journal of the American Academy of Dermatology

authors： Unis ME,Pfau RG,Patel H,Takahashi Y,Anhalt GJ

更新日期：1985-08-01 00:00:00

abstract：:Hirsutism in women is frequently associated with increased levels of androgens. Studies of biochemical changes, however, have yielded conflicting results. This study compares the findings in 30 hirsute women with normal menses and those of 30 hirsute women with abnormal cycles. Of the women with abnormal menstruation,...

journal_title：Journal of the American Academy of Dermatology

authors： Redmond GP,Bergfeld W,Gupta M,Bedocs NM,Skibinski C,Gidwani G

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:Noninvoluting congenital hemangioma (NICH) is a distinct vascular tumor of infancy. OBJECTIVE:We describe the clinical characteristics, histopathology, imaging, and natural history of NICH and compare our findings with previous reports. METHODS:We conducted a retrospective review of charts and photographic...

journal_title：Journal of the American Academy of Dermatology

authors： Lee PW,Frieden IJ,Streicher JL,McCalmont T,Haggstrom AN

更新日期：2014-05-01 00:00:00

abstract：:Most cutaneous squamous cell carcinomas (SCCs) of the trunk and extremities are small enough to be cured by simple surgical excision. Because the risk of metastasis of SCCs of the head and neck arising from mucosal surfaces is higher than the risk of metastasis of SCCs arising from cutaneous surfaces, it may be more a...

journal_title：Journal of the American Academy of Dermatology

authors： Geohas J,Roholt NS,Robinson JK

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Cutaneous leishmaniasis (CL) is caused by different species of Leishmania and transmitted by the bite of infected sand flies. It is a health problem in many countries. OBJECTIVE:This study was performed to assess the evidence for the efficacy of different therapeutic modalities for acute Old World CL, which...

journal_title：Journal of the American Academy of Dermatology

authors： Khatami A,Firooz A,Gorouhi F,Dowlati Y

更新日期：2007-08-01 00:00:00

abstract：:A 5-month-old boy with hypomelanosis of Ito was studied. Lesions presented as bizarre, hypopigmented whorls and streaks. Histologic studies showed that the hypopigmented areas contained normal melanocytes with decreased content of intracellular melanin. A review of the literature revealed the disease to be a discrete ...

journal_title：Journal of the American Academy of Dermatology

authors： Buzas JW,Sina B,Burnett JW

更新日期：1981-02-01 00:00:00

abstract：:Desmoplastic malignant melanoma is a rare neoplasm consisting primarily of spindle-shaped melanoma cells embedded in a fibrous stroma, with approximately 6% of cases occurring in the lip. A literature search revealed that most reported cases occur in sun-exposed areas in older men. Few cases of desmoplastic malignant ...

journal_title：Journal of the American Academy of Dermatology

authors： Hui JI,Linden KG,Barr RJ

更新日期：2002-12-01 00:00:00

abstract：BACKGROUND:Surgeons use absorbable and nonabsorbable sutures for epidermal wound closure. No large, randomized studies have compared the effect of these suture types on facial scar appearance. OBJECTIVE:To assess postsurgical facial scar appearance using either rapidly absorbable polyglactin 910 or nylon for epidermal...

journal_title：Journal of the American Academy of Dermatology

authors： Moran B,Humphrey S,Seal A,Berkowitz J,Zloty D

更新日期：2020-11-01 00:00:00

abstract：BACKGROUND:Many targeted therapies used in the treatment of cancer can lead to the development of xerosis, but the incidence and relative risk of xerosis have not been ascertained. OBJECTIVE:We conducted a systematic review and metaanalysis of clinical trials, to ascertain the incidence and risk of developing xerosis ...

journal_title：Journal of the American Academy of Dermatology

authors： Valentine J,Belum VR,Duran J,Ciccolini K,Schindler K,Wu S,Lacouture ME

更新日期：2015-04-01 00:00:00

abstract：BACKGROUND:The enzyme indoleamine 2,3-dioxygenase (IDO) degrades the essential amino acid tryptophan, and this degradation is an immunosuppressive mechanism that is mainly used by antigen-presenting cells. IDO-expressing dendritic cells and macrophages have previously been identified as components of lymph node granulo...

journal_title：Journal of the American Academy of Dermatology

authors： von Bubnoff D,Scheler M,Wilms H,Wenzel J,von Bubnoff N,Häcker G,Schultze J,Popov A,Racz P,Bieber T,Wickenhauser C

更新日期：2011-10-01 00:00:00

abstract：:A 22-month-old boy had xanthomatous skin lesions, neurofibromatosis, and chronic granulocytic leukemia. Histologic examination of the xanthomatous skin lesions disclosed juvenile xanthogranulomas. Twenty-three previously published cases of this association are reviewed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Morier P,Mérot Y,Paccaud D,Beck D,Frenk E

更新日期：1990-05-01 00:00:00

abstract：:Sulfur is a time-honored therapeutic agent useful in a variety of dermatologic disorders. Its keratolytic action is due to formation of hydrogen sulfide through a reaction that depends upon direct interaction between sulfur particles and keratinocytes. The smaller the particle size, the greater the degree of such inte...

journal_title：Journal of the American Academy of Dermatology

authors： Lin AN,Reimer RJ,Carter DM

更新日期：1988-03-01 00:00:00

abstract：:Chemexfoliation (chemical peeling) is being used to obtain both therapeutic (e.g., actinic keratoses) and cosmetic (e.g., removal of fine facial rhytides) benefits. Phenol, one of the most widely used agents for inducing cutaneous exfoliation, may induce cardiac arrhythmias and is toxic to the liver and kidneys. Trich...

journal_title：Journal of the American Academy of Dermatology

authors： Lober CW

更新日期：1987-07-01 00:00:00

abstract：BACKGROUND:HLA-DR1 is associated with the development of multiple basal cell carcinomas (BCC). However, the association is weak. OBJECTIVE:The purpose of our study was to determine whether HLA-DR1 is a marker for susceptibility to the development of many BCCs during a lifetime. METHODS:Persons with multiple BCCs were...

journal_title：Journal of the American Academy of Dermatology

authors： Czarnecki D,Lewis A,Nicholson I,Tait B,Nash C

更新日期：1992-05-01 00:00:00

abstract：:Blue-brown macules of the face occurring on both sides of the forehead, temple, eyelids, malar area, alae of the nose, and root of the nose are often observed in middle-aged Japanese women. These lesions histologically are a form of dermal melanocytosis as shown by electron microscopic examination. They differ clinica...

journal_title：Journal of the American Academy of Dermatology

authors： Hori Y,Kawashima M,Oohara K,Kukita A

更新日期：1984-06-01 00:00:00

abstract：:Thimerosal, a mercuric derivative of thiosalicylic acid, is a preservative used in several types of consumer products, including cosmetics, ophthalmic and otolaryngologic medications, and vaccines. As a result of allergic reactions and environmental concerns, its use has declined significantly during the past 2 decade...

journal_title：Journal of the American Academy of Dermatology

authors： Suneja T,Belsito DV

更新日期：2001-07-01 00:00:00

abstract：BACKGROUND:The prognosis of drug-induced hypersensitivity syndrome (DiHS)/drug reaction with eosinophilia and systemic symptoms (DRESS) is highly unpredictable. Severe complications, either related or unrelated to cytomegalovirus (CMV) reactivation, are a highly probable cause of death. OBJECTIVES:The aim was to estab...

journal_title：Journal of the American Academy of Dermatology

authors： Mizukawa Y,Hirahara K,Kano Y,Shiohara T

更新日期：2019-03-01 00:00:00

abstract：:Poison ivy, poison oak, and poison sumac are now classified in the genus Toxicodendron which is readily distinguished from Rhus. In the United States, there are two species of poison oak, Toxicodendron diversilobum (western poison oak) and Toxicodendron toxicarium (eastern poison oak). There are also two species of po...

journal_title：Journal of the American Academy of Dermatology

authors： Guin JD,Gillis WT,Beaman JH

更新日期：1981-01-01 00:00:00

abstract：:Thirteen patients with moderate to severe rhinophyma were treated with electrosurgery. All patients achieved cosmetic improvement with minimal postoperative complications. Six of 13 patients noted an improvement in nasal breathing after treatment. Patients with a predominantly lobular rhinophyma achieved the best over...

journal_title：Journal of the American Academy of Dermatology

authors： Clark DP,Hanke CW

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:Recombinant human platelet derived growth factor-BB gel (PDGF gel) has been shown to be effective in the treatment of diabetic neuropathic ulcers. It is also being used off-label to speed wound healing of flaps, grafts, and wounds from Mohs micrographic surgery. OBJECTIVE:The purpose of the study was to com...

journal_title：Journal of the American Academy of Dermatology

authors： Cohen MA,Eaglstein WH

更新日期：2001-12-01 00:00:00

abstract：:Human papillomavirus (HPV) is responsible for common condyloma acuminata and a number of premalignant and malignant anogenital lesions. These conditions are of particular concern in immunocompromised individuals who have higher risk of malignant transformation and are more difficult to treat. This is part I of a two-p...

journal_title：Journal of the American Academy of Dermatology

authors： Gormley RH,Kovarik CL

更新日期：2012-06-01 00:00:00

abstract：:The advent of electron microscopy and immunohistochemical stains allowed for reclassification of the histiocytoses based on the predominant cell in the infiltrate. Although the current schema simplicity provides a good foundation, some patients display overlapping clinical and immunohistochemical features that defy cl...

journal_title：Journal of the American Academy of Dermatology

authors： Satter EK,Gendernalik SB,Galeckas KJ

更新日期：2009-05-01 00:00:00

abstract：:Thyroid autoimmunity has been increasingly reported to be associated with chronic urticaria and angioedema. The administration of thyroid hormone may alleviate chronic urticaria and/or angioedema in selected patients. This review focuses on the association of thyroid autoimmunity with chronic urticaria and/or angioede...

journal_title：Journal of the American Academy of Dermatology

authors： Heymann WR

更新日期：1999-02-01 00:00:00