Cutaneous squamous cell carcinomas consistently show histologic evidence of in situ changes: a clinicopathologic correlation.

abstract：BACKGROUND:No large studies have defined the best treatment of actinic cheilitis. METHODS:We conducted a systematic review to define the best therapies for actinic cheilitis in clinical response and recurrences. RESULTS:We first identified 444 papers, and 49 were finally considered, including 789 patients and 843 tre...

journal_title：Journal of the American Academy of Dermatology

authors： Lai M,Pampena R,Cornacchia L,Pellacani G,Peris K,Longo C

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Despite multiple therapeutic approaches for nephrogenic systemic fibrosis (NSF), no single treatment has convincingly shown consistent benefit. The most successful outcomes have been associated with recovery of renal function, although evidence remains limited and past studies have been inconclusive. OBJECT...

journal_title：Journal of the American Academy of Dermatology

authors： Wilson J,Gleghorn K,Seigel Q,Kelly B

更新日期：2017-08-01 00:00:00

abstract：:Hirsutism in women is frequently associated with increased levels of androgens. Studies of biochemical changes, however, have yielded conflicting results. This study compares the findings in 30 hirsute women with normal menses and those of 30 hirsute women with abnormal cycles. Of the women with abnormal menstruation,...

journal_title：Journal of the American Academy of Dermatology

authors： Redmond GP,Bergfeld W,Gupta M,Bedocs NM,Skibinski C,Gidwani G

更新日期：1990-01-01 00:00:00

abstract：:Onychomadesis is defined as spontaneous separation of the nail plate from the nail bed, beginning at its proximal end and resulting in the shedding of the nail. It has been associated with a variety of clinical settings, including systemic illnesses, generalized skin diseases, and drug therapies. There have been a sma...

journal_title：Journal of the American Academy of Dermatology

authors： Mehra A,Murphy RJ,Wilson BB

更新日期：2000-08-01 00:00:00

abstract：:The efficacy of a sunscreen containing an investigational drug, butyl methoxydibenzoylmethane in combination with padimate O against the erythemogenic effect of ultraviolet A (UVA) radiation was evaluated in two double-blind studies involving subjects sensitized with topical 8-methoxypsoralen. UVA radiation was suppli...

journal_title：Journal of the American Academy of Dermatology

authors： Lowe NJ,Dromgoole SH,Sefton J,Bourget T,Weingarten D

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:Recent studies suggest that ultraviolet (UV) A1 phototherapy is an effective treatment for localized scleroderma (LS); however, the optimum UVA1 dose remains to be determined. OBJECTIVE:We sought to compare the immediate and long-term efficacy of low- versus medium-dose UVA1 phototherapy for plaque-type LS....

journal_title：Journal of the American Academy of Dermatology

authors： Sator PG,Radakovic S,Schulmeister K,Hönigsmann H,Tanew A

更新日期：2009-05-01 00:00:00

abstract：:We describe a 6-year-old boy with a granulomatous lesion on the upper aspect of his left arm. Fusarium solani infection was confirmed by biopsy studies and cultures. The biopsy specimen showed an unusually extensive dermal invasion with fungal hyphae. This is an uncommon clinical presentation for deep cutaneous infect...

journal_title：Journal of the American Academy of Dermatology

authors： Nakamura Y,Xu X,Saito Y,Tateishi T,Takahashi T,Kawachi Y,Otsuka F

更新日期：2007-05-01 00:00:00

abstract：:Disseminated histoplasmosis is being diagnosed more frequently in persons infected with the human immunodeficiency virus and is often the initial manifestation of the acquired immunodeficiency syndrome (AIDS). Disease-related cutaneous features of HIV-associated disseminated histoplasmosis are defined as mucocutaneous...

journal_title：Journal of the American Academy of Dermatology

authors： Cohen PR,Bank DE,Silvers DN,Grossman ME

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Sturge-Weber syndrome (SWS) is characterized by port-wine stains (PWS) affecting the face, eyes, and central nervous system. Pulsed dye laser (PDL) is the standard treatment for PWS. Unfortunately, recurrence is frequent because of reformation and reperfusion of blood vessels. OBJECTIVE:We sought to assess ...

journal_title：Journal of the American Academy of Dermatology

authors： Marqués L,Núñez-Córdoba JM,Aguado L,Pretel M,Boixeda P,Nagore E,Baselga E,Redondo P

更新日期：2015-01-01 00:00:00

abstract：:Linear IgA bullous dermatosis (LABD) is an autoimmune blistering skin disease characterized by circulating IgA antibodies binding the basement membrane zone. In most cases the origin is not clear, but in a minority of cases LABD is drug induced. We describe a patient in whom linear IgA disease developed shortly after ...

journal_title：Journal of the American Academy of Dermatology

authors： König C,Eickert A,Scharfetter-Kochanek K,Krieg T,Hunzelmann N

更新日期：2001-04-01 00:00:00

abstract：:A 7-week-old male infant with a seizure disorder and an extensive sebaceous nevus of the scalp was examined. Computerized axial tomography (CAT) scan identified an intracerebral mass which proved to be a hamartomatous malofrmation fo the brain. The association of intracranial masses with sebaceous nevi should be recog...

journal_title：Journal of the American Academy of Dermatology

authors： Moskowitz R,Honig PJ

更新日期：1982-06-01 00:00:00

abstract：INTRODUCTION:Intravenous immunoglobulin (IVIG) is used to treat many inflammatory and autoimmune disorders and although generally well tolerated, cutaneous side effects occur. OBJECTIVE:We reviewed reports of pompholyx and eczematous reactions associated with IVIG. METHODS:A literature search was performed using the ...

journal_title：Journal of the American Academy of Dermatology

authors： Gerstenblith MR,Antony AK,Junkins-Hopkins JM,Abuav R

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Voriconazole, an antifungal agent, is associated with various cutaneous reactions, including phototoxicity, accelerated photoaging, and skin cancer. Incidence and risk factors for these reactions in children have not been well described. OBJECTIVE:We sought to determine the incidence of and factors associat...

journal_title：Journal of the American Academy of Dermatology

authors： Sheu J,Hawryluk EB,Guo D,London WB,Huang JT

更新日期：2015-02-01 00:00:00

abstract：:We describe a family with the unusual association of Cowden's disease and Bannayan-Riley-Ruvalcaba syndrome. The father has characteristic mucocutaneous features that are palmoplantar keratoses, multiple facial papules, oral papillomatoses, lipomas, and vitiligo with involvement of the thyroid and digestive tract. The...

journal_title：Journal of the American Academy of Dermatology

authors： Perriard J,Saurat JH,Harms M

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Atypical fibroxanthoma (AFX) is a fibrohistiocytic tumor with relatively high local recurrence rates but low metastatic potential. Wide local excision (WLE) and Mohs micrographic surgery (MMS) are common treatments, although no consensus exists regarding optimal therapy. OBJECTIVE:To systematically review e...

journal_title：Journal of the American Academy of Dermatology

authors： Tolkachjov SN,Kelley BF,Alahdab F,Erwin PJ,Brewer JD

更新日期：2018-11-01 00:00:00

abstract：:We review experimental studies that address age-related changes in cutaneous barrier function and dermal blood vessel function. These differences have important implications in the understanding of age-related changes in the inflammatory process and topical drug delivery systems. ...

journal_title：Journal of the American Academy of Dermatology

authors： Harvell JD,Maibach HI

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Acne is one of the most common concerns of patients with body dysmorphic disorder (BDD), a psychiatric condition defined as a preoccupation with a slight or imagined defect in appearance that causes significant disruption in daily functioning. OBJECTIVE:We sought to screen for BDD symptoms among patients wi...

journal_title：Journal of the American Academy of Dermatology

authors： Bowe WP,Leyden JJ,Crerand CE,Sarwer DB,Margolis DJ

更新日期：2007-08-01 00:00:00

abstract：:A 39-year-ole man developed edema and vesiculation of the oral mucosa following the application of benzocaine (Hurricaine) gel. Open testing demonstrated an immediate urticarial reaction. Closed patch tests were positive after 48 hours. The contact dermatitis was consistent with a delayed-type hypersensitivity. It app...

journal_title：Journal of the American Academy of Dermatology

authors： Ryan ME,Davis BM,Marks JG Jr

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND:UVA induces tissue damage via the production of radical oxygen species. Adding antioxidants to UV filters in sunscreens is a novel photoprotective strategy. The topical application of antioxidants in sunscreen can potentially neutralize the UVA-induced free radicals. OBJECTIVES:We sought to assess the degre...

journal_title：Journal of the American Academy of Dermatology

authors： Wang SQ,Osterwalder U,Jung K

更新日期：2011-09-01 00:00:00

abstract：:Pruritus is a common and often times difficult to treat symptom in many dermatologic and systemic diseases. For pruritus with an inflammatory or autoimmune origin, therapies such as topical corticosteroids and antihistamines are often initiated. However, in the case that these and additional systemic therapies are ine...

journal_title：Journal of the American Academy of Dermatology

authors： Sharma D,Kwatra SG

更新日期：2016-02-01 00:00:00

abstract：BACKGROUND:Patients with cutaneous lupus erythematosus (LE) and a history of disease- related photoaggravation, confirmed by phototesting, may not respond to photoprotection and/or medical intervention. Ultraviolet B-hardening therapy may improve tolerance for environmental ultraviolet radiation (UVR) in photosensitive...

journal_title：Journal of the American Academy of Dermatology

authors： Sanders CJ,Lam HY,Bruijnzeel-Koomen CA,Sigurdsson V,van Weelden H

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Cutaneous polyarteritis nodosa (cPAN) is a skin medium vessel neutrophilic arteritis with livedo, nodules, and ulcerations. Macular lymphocytic arteritis (MLA) is a small arteritis with erythematous or pigmented macules and typical histologic features (a lymphocytic infiltrate, concentric fibrin ring, no dis...

journal_title：Journal of the American Academy of Dermatology

authors： Buffiere-Morgado A,Battistella M,Vignon-Pennamen MD,de Masson A,Rybojad M,Petit A,Cordoliani F,Begon E,Flageul B,Mahr A,Bagot M,Bouaziz JD

更新日期：2015-12-01 00:00:00

abstract：:Metastatic Crohn's disease (CD) is a rare cutaneous manifestation of CD that was first described nearly 50 years ago. Many subsequent reports have defined its most common clinical and histopathologic features. The pathogenesis underlying metastatic CD is unknown but various hypotheses exist. An established standard th...

journal_title：Journal of the American Academy of Dermatology

authors： Kurtzman DJ,Jones T,Lian F,Peng LS

更新日期：2014-10-01 00:00:00

abstract：:A case is presented in which a patient experienced the development of both Dupuytren's disease and Peyronie's disease after single episodes of sports-related trauma. These disorders and other fibromatoses are linked not only by similar pathologic features but by increased frequency of simultaneous occurrence. Some gen...

journal_title：Journal of the American Academy of Dermatology

authors： Connelly TJ

更新日期：1999-07-01 00:00:00

abstract：:Molecular and cellular understanding of psoriasis pathogenesis has evolved considerably over the last 30 years beginning in the early 1980s when psoriasis was thought to be a skin disease driven by keratinocyte hyperproliferation. During the next 20 years, the role of the immune system and T-helper (Th) cells in psori...

journal_title：Journal of the American Academy of Dermatology

authors： Lynde CW,Poulin Y,Vender R,Bourcier M,Khalil S

更新日期：2014-07-01 00:00:00

abstract：:Keratoacanthomas infrequently are treated by radiotherapy. However, keratoacanthomas that are recurrent after surgical excision or whose resection would result in cosmetic deformity may benefit from radiotherapy. Between January 1970 and June 1988, 29 such keratoacanthomas in 18 patients were irradiated. Doses ranged ...

journal_title：Journal of the American Academy of Dermatology

authors： Donahue B,Cooper JS,Rush S

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Some hereditary palmoplantar keratodermas (PPK) have been defined at the molecular level. OBJECTIVE:Our purpose was to establish the cause of a hereditary PPK with unique histopathologic findings in the epidermis. METHODS:Investigative studies included light and electron microscopy and determination of gen...

journal_title：Journal of the American Academy of Dermatology

authors： Magro CM,Baden LA,Crowson AN,Bowden PE,Baden HP

更新日期：1997-07-01 00:00:00

abstract：BACKGROUND:Embryofetal developmental toxicity associated with oral administration of vitamin A analogs has led to concern about risks from topical application. OBJECTIVE:This study was conducted to evaluate the potential developmental toxicity of tretinoin emollient cream when applied to the skin of pregnant New Zeala...

journal_title：Journal of the American Academy of Dermatology

authors： Christian MS,Mitala JJ,Powers WJ Jr,McKenzie BE,Latriano L

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:It is important for dermatologists and other physicians in refugee-receiving countries to acquire knowledge of forensic dermatology to identify lesions from torture. OBJECTIVE:Review forensic dermatology in cases of torture. RESULTS:In providing medical assessment and care to refugees and migrants, chronic...

journal_title：Journal of the American Academy of Dermatology

authors： Deps PD,Aborghetti HP,Zambon TL,Costa VC,Dadalto Dos Santos J,Collin SM,Charlier P

更新日期：2020-09-15 00:00:00

abstract：BACKGROUND:Non-melanoma skin cancers (NMSCs) are increased in organ transplant recipients, but transplant and immunocompetent squamous and basal cell carcinomas (SCCs, BCCs) have not been compared previously in a single-center study. OBJECTIVE:To compare clinicopathologic features of transplant and immunocompetent NMS...

journal_title：Journal of the American Academy of Dermatology

authors： Harwood CA,Proby CM,McGregor JM,Sheaff MT,Leigh IM,Cerio R

更新日期：2006-02-01 00:00:00