Percutaneous absorption and inflammation in aged skin: a review.

abstract：:A case of porphyria cutanea tarda in a human immunodeficiency virus-infected patient with hemophilia is reported. Onset of skin manifestations of porphyria cutanea tarda coincided with deterioration of immune function. However, acquired immunodeficiency syndrome has not yet developed with a follow-up interval of 39 mo...

journal_title：Journal of the American Academy of Dermatology

authors： Conlan MG,Hoots WK

更新日期：1992-05-01 00:00:00

abstract：BACKGROUND:Nephrogenic systemic fibrosis is a fibrosing disorder associated with gadolinium (Gd)-based contrast agents dosed during renal insufficiency. OBJECTIVE:In two patients, Gd deposition in tissue affected by nephrogenic systemic fibrosis was quantified using inductively coupled plasma mass spectrometry. The pr...

journal_title：Journal of the American Academy of Dermatology

authors： High WA,Ranville JF,Brown M,Punshon T,Lanzirotti A,Jackson BP

更新日期：2010-01-01 00:00:00

abstract：:A 7.3-year prospective study of 1,380 patients with psoriasis who were treated with oral methoxsalen (8-methoxypsoralen) and ultraviolet A photochemotherapy (PUVA) revealed that patients who continued on PUVA therapy used inpatient hospital treatment less than one fourth as often as those who had discontinued treatmen...

journal_title：Journal of the American Academy of Dermatology

authors： Stern RS

更新日期：1986-03-01 00:00:00

abstract：:Two children who had classic maple syrup urine disease developed an eruptive dermatitis when plasma isoleucine levels, leucine levels, or both fell below normal during periods of protein restriction. The dermatitis was resistant to topical corticosteroid therapy. Rapid resolution occurred after treatment with isoleuci...

journal_title：Journal of the American Academy of Dermatology

authors： Koch SE,Packman S,Koch TK,Williams ML

更新日期：1993-02-01 00:00:00

abstract：BACKGROUND:It was unclear whether an increased number of common nevi (moles) predicts melanoma death. OBJECTIVE:We prospectively examined the association between number of common nevi and risk of melanoma death. METHODS:Our study used data from the Nurses' Health Study (n = 77,288 women) and Health Professionals Foll...

journal_title：Journal of the American Academy of Dermatology

authors： Li WQ,Cho E,Weinstock MA,Li S,Stampfer MJ,Qureshi AA

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:There is currently no universally adopted terminology for defining human surface anatomic location. The lack of precision, accuracy, and reliability of terms used by health care providers, in particular dermatologic surgeons, is unsatisfactory both for epidemiologic research and for high-quality patient care...

journal_title：Journal of the American Academy of Dermatology

authors： Kenneweg KA,Halpern AC,Chalmers RJG,Soyer HP,Weichenthal M,Molenda MA

更新日期：2019-06-01 00:00:00

abstract：:Keloidal scars are abnormal scars of uncertain etiology with a predilection for certain racial groups. Although many articles have been published on the management of these scars, there are no definitive treatment protocols. Our objective was to examine the scientific quality of the literature on therapy for keloidal ...

journal_title：Journal of the American Academy of Dermatology

authors： Shaffer JJ,Taylor SC,Cook-Bolden F

更新日期：2002-02-01 00:00:00

abstract：:A case of malignant bronchial carcinoid with multiple cutaneous metastases is reported. Despite the extremely aggressive behavior of the disease and the presence of multiple hepatic metastases, the patient did not exhibit the usual clinical features of the carcinoid syndrome. The relevance of the finding of elevated 2...

journal_title：Journal of the American Academy of Dermatology

authors： Archer CB,Wells RS,MacDonald DM

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Lack of agreement on how to accurately capture disease outcomes in localized scleroderma (LS) has hindered the development of efficacious treatment protocols. The LS Cutaneous Assessment Tool (LoSCAT), consisting of the modified LS Skin Severity Index (mLoSSI) and the LS Damage Index, has potential for use i...

journal_title：Journal of the American Academy of Dermatology

authors： Kelsey CE,Torok KS

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:The reported efficacy of imiquimod for lentigo maligna varies widely, without consensus on tumor or treatment factors that can impact tumor clearance. OBJECTIVE:We sought to provide a more precise estimate of clearance rates in patients with lentigo maligna who are treated with imiquimod and to analyze fact...

journal_title：Journal of the American Academy of Dermatology

authors： Mora AN,Karia PS,Nguyen BM

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Fibrous hamartoma (FH) of infancy is a benign mesenchymal tumor, occurring as a superficial mass. Complete excision is curative. OBJECTIVE AND METHODS:The clinical features and treatment results of 18 children with FH are described. RESULTS:Local excision was the most common procedure. Surgery was radical ...

journal_title：Journal of the American Academy of Dermatology

authors： Carretto E,Dall'Igna P,Alaggio R,Siracusa F,Granata C,Ferrari A,Cecchetto G

更新日期：2006-05-01 00:00:00

abstract：:A man with phenylketonuria who was reported to have lichen sclerosus et atrophicus at age 16 years presented to our institution 35 years later with large confluent areas of atrophy. Although sclerodermatous changes have been described in children with phenylketonuria, this case offers a longitudinal view of the progre...

journal_title：Journal of the American Academy of Dermatology

authors： Belloso LM,Lowitt MH

更新日期：2003-08-01 00:00:00

abstract：:We report a patient with a vesiculopustular eruption with features distinct from typical subcorneal pustular dermatosis. Clinically, well-formed pustular lesions, which were flowerlike in appearance, were present. Histopathologically, early vesicular lesions showed intraepidermal bullae containing numerous neutrophils...

journal_title：Journal of the American Academy of Dermatology

authors： Kuan YZ,Chiou HT,Chang HC,Chan HL,Kuo TT

更新日期：1990-05-01 00:00:00

abstract：:This study compares the histopathologic characteristics of photodistributed and nonphotodistributed lichenoid drug eruptions in 13 patients. Both types have been said to be, in an unknown proportion, different from idiopathic lichen planus in that they can involve the deep as well as the superficial plexus, can contai...

journal_title：Journal of the American Academy of Dermatology

authors： West AJ,Berger TG,LeBoit PE

更新日期：1990-10-01 00:00:00

abstract：:We present the identification and characterization of two patients with xeroderma pigmentosum (XP) and squamous cell carcinoma of the tongue. Dermal fibroblasts from two black siblings with XP were shown to be hypersensitive to ultraviolet (UV) light measured by colony-forming ability. UV-induced unscheduled deoxyribo...

journal_title：Journal of the American Academy of Dermatology

authors： Wade MH,Plotnick H

更新日期：1985-03-01 00:00:00

abstract：:A newcomer in the cosmetic market, the tan accelerator, has stimulated much publicity in recent months. We studied the effects of two brands of this product, used according to package instructions, in eighteen healthy volunteers. Readings at 24, 72, 96 hours, and 1 week failed to show augmented tanning. Our study cont...

journal_title：Journal of the American Academy of Dermatology

authors： Jaworsky C,Ratz JL,Dijkstra JW

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:Dermatophytic infections of the fingernail can be effectively treated with oral antifungal agents; however, a long duration of treatment, generally several months, is required for cure. OBJECTIVE:Our purpose was to compare the efficacies of short-duration treatment with terbinafine and griseofulvin in the m...

journal_title：Journal of the American Academy of Dermatology

authors： Haneke E,Tausch I,Bräutigam M,Weidinger G,Welzel D

更新日期：1995-01-01 00:00:00

abstract：:George Cheyne Shattuck's 1808 dissertation on structure and function of the skin is one of the earliest American writings on the topic of skin diseases. Although this essay contributed no important new observations, it does provide insight into the attitudes of American physicians in the post-Revolutionary War period ...

journal_title：Journal of the American Academy of Dermatology

authors： Valentine MC

更新日期：2002-04-01 00:00:00

abstract：BACKGROUND:In recent years, increasing emphasis has been placed on value-based health care delivery. Dermatology must develop performance measures to judge the quality of services provided. The implementation of a national complication registry is one such method of tracking surgical outcomes and monitoring the safety ...

journal_title：Journal of the American Academy of Dermatology

authors： Council ML,Alam M,Gloster HM Jr,Bordeaux JS,Carroll BT,Leitenberger JJ,Wisco OJ,Maher IA

更新日期：2016-04-01 00:00:00

abstract：:Papular mucinosis is a rare, idiopathic cutaneous mucinosis that is typically chronic and progressively severe. We present a case of a 59-year-old woman with a 6-month history of a dramatic papular eruption on her face and neck, with no associated internal organ involvement. A biopsy specimen demonstrated increased de...

journal_title：Journal of the American Academy of Dermatology

authors： Sperber BR,Allee J,James WD

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:The histopathological and clinical overlapping features between condyloma acuminata and bowenoid papulosis can present a diagnostic challenge and we sought to determine if immunochemistry can be helpful in this setting. OBJECTIVE:In this study, we evaluate the specificity and sensitivity of p16 immunohistoc...

journal_title：Journal of the American Academy of Dermatology

authors： Kazlouskaya V,Shustef E,Allam SH,Lal K,Elston D

更新日期：2013-09-01 00:00:00

abstract：:Blisters from five patients with porphyria cutanea tarda and two patients with drug-induced pseudoporphyria were examined by direct immunofluorescence and by immunofluorescence mapping with antibodies against laminin and type IV collagen to determine the level of subepidermal separation. Primary screening by direct im...

journal_title：Journal of the American Academy of Dermatology

authors： Dabski C,Beutner EH

更新日期：1991-07-01 00:00:00

abstract：:We report a case of fatal pancreatitis heralded by the presence of cutaneous panniculitis without abdominal pain or other stigmata of the disease. Although cutaneous fat necrosis has been associated with pancreatitis, it is unusual as the presenting complaint of this relatively common disease. In vitro evidence sugges...

journal_title：Journal of the American Academy of Dermatology

authors： Berman B,Conteas C,Smith B,Leong S,Hornbeck L 3rd

更新日期：1987-08-01 00:00:00

abstract：BACKGROUND:The autoantibody-mediated disease in fogo selvagem (FS) is aggravated by sunlight exposure. OBJECTIVE:The aim of this study was to test whether UVB exposure of uninvolved skin of patients with FS (n = 21) enhances epidermal acantholysis and in vivo binding of FS autoantibodies as compared with a control gro...

journal_title：Journal of the American Academy of Dermatology

authors： Reis VM,Toledo RP,Lopez A,Diaz LA,Martins JE

更新日期：2000-04-01 00:00:00

abstract：:Dialogues in Dermatology, a monthly audio program from the American Academy of Dermatology, contains discussions between dermatologists on timely topics. Commentaries from Dialogues Editor-in-Chief Warren R. Heymann, MD, are provided after each discussion as a topic summary and are provided here as a special service t...

journal_title：Journal of the American Academy of Dermatology

authors： Heymann WR

更新日期：2007-04-01 00:00:00

abstract：:Removal of Norplant contraceptive implants may be rendered difficult by the size of the capsules and variations in insertion technique. In the standard removal technique, a single transverse incision is made close to and below the distal ends of the capsules, and a mosquito forceps is used for extraction. Described,...

journal_title：Journal of the American Academy of Dermatology

authors： Lam M,Tope WD

更新日期：1997-11-01 00:00:00

abstract：:Melasma is an irregular brown or grayish-brown facial hypermelanosis, often affecting women, especially those living in areas of intense UV radiation. The precise cause of melasma remains unknown; however, there are many possible contributing factors. Because of its dermal component and tendency to relapse, melasma is...

journal_title：Journal of the American Academy of Dermatology

authors： Gupta AK,Gover MD,Nouri K,Taylor S

更新日期：2006-12-01 00:00:00

abstract：:Twenty-six lymph node biopsy specimens from twenty-three patients with Sézary syndrome were microscopically evaluated and compared with nodal specimens from six patients with pre-Sézary syndrome and four control patients with dermatopathic lymphadenopathy. Three phases of nodal involvement by cerebriform lymphocytes w...

journal_title：Journal of the American Academy of Dermatology

authors： Buzzanga J,Banks PM,Winkelmann RK

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:Concern has been raised about the potential long-term effects of propranolol treatment for infantile hemangioma (IH). OBJECTIVES:We sought to assess psychologic (social, emotional, behavioral, and executive) functioning in children treated with propranolol for IH. METHODS:Twenty-seven patients with IH (6.1...

journal_title：Journal of the American Academy of Dermatology

authors： Moyakine AV,Spillekom-van Koulil S,van der Vleuten CJM

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:Vascular cell adhesion molecule-1 (VCAM-1) is an endothelial protein with adhesive properties for inflammatory cells including lymphocytes. Its role in skin disease and regulation in vivo are uncertain. OBJECTIVE:Our purpose was to determine expression of VCAM-1 in normal and inflamed skin and the effect on...

journal_title：Journal of the American Academy of Dermatology

authors： Groves RW,Ross EL,Barker JN,MacDonald DM

更新日期：1993-07-01 00:00:00