Fibrous hamartoma of infancy: an Italian multi-institutional experience.

Abstract:

BACKGROUND:Fibrous hamartoma (FH) of infancy is a benign mesenchymal tumor, occurring as a superficial mass. Complete excision is curative. OBJECTIVE AND METHODS:The clinical features and treatment results of 18 children with FH are described. RESULTS:Local excision was the most common procedure. Surgery was radical in 10 patients, with microscopic residual disease in 6; all of them are alive with no evidence of disease 2 to 49 months after diagnosis. One patient, treated with a local reexcision for macroscopic residual disease (and chemotherapy for a synchronous desmoid fibromatosis) is well 83 months after diagnosis; the last patient, with a lesion of the labia majora, only underwent biopsy and is doing well, awaiting plastic surgery. LIMITATIONS:The results did not reach statistical significance due to difficulties in collecting cases. CONCLUSIONS:FH should be treated by complete excision; in our experience a nonradical excision was also able to achieve the cure. An aggressive approach should be avoided, as the overall prognosis is excellent.

journal_name

J Am Acad Dermatol

authors

Carretto E,Dall'Igna P,Alaggio R,Siracusa F,Granata C,Ferrari A,Cecchetto G

doi

10.1016/j.jaad.2005.11.1076

subject

Has Abstract

pub_date

2006-05-01 00:00:00

pages

800-3

issue

5

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(05)04619-0

journal_volume

54

pub_type

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