Abstract：
BACKGROUND:Australia has one of the highest rates of skin cancer globally. Lifetime risk is associated with childhood sun exposure. OBJECTIVE:We sought to investigate whether skin cancer prevention programs have resulted in improvements in sun-exposure and sun-protection behavior among young children in tropical Australia. METHODS:Two cohorts of 12-to 35-month-old children from Townsville, Australia, were compared: cohort 1 was recruited from hospital birth records (1991) and cohort 2 was recruited via local child-care centers (1999-2002). Children's phenotypic characteristics were assessed. Parents completed questionnaires detailing children's demographic characteristics, and sun-exposure and sun-protective practices. RESULTS:Although 1-year-old children from cohort 2 spent more time in the sun than those from cohort 1 (median 2.2 vs 2.8 h/d; P = .002), a higher proportion almost always wore sunscreen and a swim-shirt year round. Although more 1-year-old children in cohort 2 had experienced a sunburn (35.5% vs 51.2%; P = .007), both cohort 2 age groups experienced fewer hours of sun exposure to the back of the trunk (P < .001), were less likely to have been sunburned on the back/shoulders (age 1 year 34.8% vs 10.1% and age 2 years 52% vs 10.1%; P < .001), and acquired fewer melanocytic nevi at these sites (P < .001). LIMITATIONS:There was potential for socially desirable responses (information bias). CONCLUSION:Although duration of sun exposure in early childhood did not decrease during an 8-year period, reported use of personal sun protection did. The observed increase in popularity of swim-shirts and sunscreen between cohorts coincided with the development of significantly fewer melanocytic nevi in these children.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Smith A,Harrison S,Nowak M,Buettner P,Maclennan Rdoi
10.1016/j.jaad.2012.10.057subject
Has Abstractpub_date
2013-05-01 00:00:00pages
774-83issue
5eissn
0190-9622issn
1097-6787pii
S0190-9622(12)01197-8journal_volume
68pub_type
杂志文章abstract：:Dermatomyositis (DM) is an idiopathic inflammatory myopathy. The mainstay of treatment for DM is oral corticosteroids. However, the dose and length of treatment is debated. Adding to the confusion, there have been no randomized controlled studies comparing the use of various corticosteroid doses and taper rates, and n...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.jaad.2008.02.043
更新日期：2008-07-01 00:00:00
abstract：BACKGROUND:Despite the prevalence of androgenetic alopecia among men, little is known about its psychological effects. OBJECTIVE:This investigation examined the psychosocial sequelae that balding men attribute to hair loss and compared balding and nonbalding men in personality functioning. METHODS:Subjects included 6...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/0190-9622(92)70134-2
更新日期：1992-06-01 00:00:00
abstract：BACKGROUND:The optimal long-term dosing strategy for adalimumab (ADA) in hidradenitis suppurativa/acne inversa (HS) was evaluated by pooling the results of the PIONEER phase 3 trials and an open-label extension (OLE) study. OBJECTIVE:To assess the response to and tolerability of long-term administration of ADA in HS. ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jaad.2018.05.040
更新日期：2019-01-01 00:00:00
abstract：:Neutrophilic dermatoses are a heterogeneous group of inflammatory skin disorders that present with unique clinical features but are unified by the presence of a sterile, predominantly neutrophilic infiltrate on histopathology. The morphology of cutaneous lesions associated with these disorders is heterogeneous, which ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/j.jaad.2017.11.064
更新日期：2018-12-01 00:00:00
abstract：BACKGROUND:Knowledge is limited regarding unknown primary Merkel cell carcinoma (UPMCC). OBJECTIVE:We sought to document the characteristics and behavior of UPMCC, and determine the most appropriate treatment. METHODS:A multicenter, retrospective, consecutive study reviewing patients given a diagnosis of UPMCC betwee...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,多中心研究,评审
doi：10.1016/j.jaad.2012.07.035
更新日期：2013-03-01 00:00:00
abstract：:Discoid lupus erythematosus lesions show hyperkeratosis and atrophy, which may reflect abnormal epidermal proliferation, differentiation, or both. In this investigation, markers for epidermal proliferation, differentiation and inflammation were studied in cutaneous lesions of discoid lupus erythematosus. Frozen sectio...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/0190-9622(91)70303-j
更新日期：1991-12-01 00:00:00
abstract：:Atopic dermatitis is a chronic inflammatory skin disease that is frequently associated with respiratory allergies. Atopic dermatitis develops as a result of a complex interrelationship of environmental, immunologic, genetic, and pharmacologic factors. Efforts to understand the relative contributions of these factors h...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1067/mjd.2001.109815
更新日期：2001-01-01 00:00:00
abstract：:Topical nitrogen mustard is an alkylating agent. Its efficacy in treating alopecia areata was reported in an uncontrolled study. We present a preliminary, half-head, controlled 16-week study showing that topical nitrogen mustard was of benefit in 1 of 6 patients treated with 50% to 100% scalp involvement. Another 4 pa...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1067/s0190-9622(03)00800-4
更新日期：2003-08-01 00:00:00
abstract：BACKGROUND:Mycoplasma pneumoniae infection has been documented in erythema multiforme (EM) and Stevens-Johnson syndrome-toxic epidermal necrosis (SJS-TEN). Clinical aspects of M pneumoniae-related EM have been poorly described in the literature. OBJECTIVE:To highlight differences between M pneumoniae EM and non-M pneu...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2018.03.013
更新日期：2018-07-01 00:00:00
abstract：:Several aspects of trichotillomania in childhood are described and discussed. Case records of twenty-one children not older than 15 years of age, who were seen in the previous 5 years, were examined. The female/male ratio was 2.5:1 (fifteen girls and six boys); the age range was 2 to 15 years. Although trichotillomani...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(86)70213-2
更新日期：1986-10-01 00:00:00
abstract：:Angiolymphoid hyperplasia with eosinophilia developed in a 13-year-old boy. The immune phenotype of infiltrating cells and the distribution of adhesion molecules of the integrin, immunoglobulin, and selectin families were analyzed with monoclonal antibodies. The infiltrate consisted mainly of helper lymphocytes, monoc...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/0190-9622(92)70109-s
更新日期：1992-05-01 00:00:00
abstract：BACKGROUND:Patients with pemphigus vulgaris (PV) are genetically linked to two alleles of the HLA subgroup, and circulating antibodies were found in first-degree relatives of these patients, thus showing genetic predisposition. OBJECTIVE:Our purpose was to determine the occurrence of circulating true PV-IgG in patient...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(97)70324-4
更新日期：1997-01-01 00:00:00
abstract：BACKGROUND:Reports suggest that cigarette smoking might interfere with the effectiveness of antimalarial therapy as first-line treatment for cutaneous lupus erythematosus. Patients refractory to this treatment often must be treated with potentially more toxic regimens. OBJECTIVE:Our purpose was to examine the effects ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 临床试验,杂志文章
doi：
更新日期：2000-06-01 00:00:00
abstract：BACKGROUND:Treatment of chronic discoid lupus erythematosus (CDLE) with a pulsed dye laser (PDL) has shown promising results, although outcomes in previous studies were not validated and laser parameters were inconsistent. OBJECTIVE:We conducted an open prospective study to assess the efficacy and safety of PDL for th...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2008.11.904
更新日期：2009-04-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(86)70288-0
更新日期：1986-12-01 00:00:00
abstract：:Forty-seven patients with chronic venous leg ulcers were included in a randomized clinical trial to evaluate the efficacy of systemically administered antibiotics in healing with condition. One group was treated by means of elastic support bandages only, whereas the other one received the same local treatment plus sys...
journal_title：Journal of the American Academy of Dermatology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0190-9622(86)70154-0
更新日期：1986-08-01 00:00:00
abstract：:Kathon CG, a cosmetics preservative containing, as active ingredients, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one, appears to be a frequent cause of contact dermatitis in Europe. In the United States, where Kathon CG was introduced some 5 years later, the use of this preservative system f...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/s0190-9622(88)70051-1
更新日期：1988-02-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/0190-9622(90)70251-c
更新日期：1990-09-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2017.03.018
更新日期：2017-08-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/s0190-9622(89)70145-6
更新日期：1989-07-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1067/mjd.2002.110663
更新日期：2002-11-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/s0190-9622(80)80385-9
更新日期：1980-02-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2006.09.023
更新日期：2007-08-01 00:00:00
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journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,评审
doi：10.1016/s0190-9622(85)70095-3
更新日期：1985-04-01 00:00:00
abstract：BACKGROUND:Non-melanoma skin cancers (NMSCs) are increased in organ transplant recipients, but transplant and immunocompetent squamous and basal cell carcinomas (SCCs, BCCs) have not been compared previously in a single-center study. OBJECTIVE:To compare clinicopathologic features of transplant and immunocompetent NMS...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2005.10.049
更新日期：2006-02-01 00:00:00
abstract：BACKGROUND:Many targeted therapies used in the treatment of cancer can lead to the development of xerosis, but the incidence and relative risk of xerosis have not been ascertained. OBJECTIVE:We conducted a systematic review and metaanalysis of clinical trials, to ascertain the incidence and risk of developing xerosis ...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.jaad.2014.12.010
更新日期：2015-04-01 00:00:00
abstract：BACKGROUND:Psoralen plus ultraviolet A (PUVA) for the treatment of psoriasis has never been evaluated using the Psoriasis Area Severity Index (PASI) in a randomized, double-blind, placebo-controlled trial. The lack of such data limits our capacity to estimate PUVA's efficacy relative to other treatment options that are...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章,随机对照试验
doi：10.1016/j.jaad.2009.04.053
更新日期：2009-11-01 00:00:00
abstract：BACKGROUND:The evidence of hairs grouped into well-defined follicular units has given a new vision of hair anatomy and pathology. The sebaceous glands and the arrector pili muscle, as part of the pilosebaceous unit, should be viewed as important parts of this organized follicular unit structure. OBJECTIVE:This study w...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2004.01.054
更新日期：2004-08-01 00:00:00
abstract：BACKGROUND:Unwanted tattoos are treated with Q-switched lasers. Despite a series of treatments, efficacy is limited. OBJECTIVE:We compared a single Q-switched laser treatment pass with 4 treatment passes separated by 20 minutes. METHODS:Eighteen tattoos on 12 adults were divided in half and randomized. One half recei...
journal_title：Journal of the American Academy of Dermatology
pub_type： 杂志文章
doi：10.1016/j.jaad.2011.07.024
更新日期：2012-02-01 00:00:00
abstract：BACKGROUND:The use of cutaneous resurfacing lasers to treat rhytides is widely accepted. Several carbon dioxide lasers, many using fundamentally different technologies, are available. OBJECTIVE:The purpose of this study was to compare the results obtained and side effects after treating rhytides with 3 different carbo...
journal_title：Journal of the American Academy of Dermatology
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1016/s0190-9622(98)70002-7
更新日期：1998-10-01 00:00:00
