Immunohistochemical detection of proliferation and differentiation in discoid lupus erythematosus.

abstract：BACKGROUND:Rituximab has been increasingly used in autoimmune blistering dermatoses, mainly in pemphigus. However, only a few larger case series are available on this subject and information on the efficacy of retreatment with rituximab during relapses is lacking. OBJECTIVE:We sought to determine efficacy and adverse ...

journal_title：Journal of the American Academy of Dermatology

authors： Kasperkiewicz M,Shimanovich I,Ludwig RJ,Rose C,Zillikens D,Schmidt E

更新日期：2011-09-01 00:00:00

abstract：:In a 4-year-old boy with steriod-resistant syndrome and extreme hyperlipidemia, an intense pruritic papular eruption developed on the trunk, buttocks, and extensor surface of the extremities. Findings from a skin biopsy specimen were consistent with an eruptive xanthoma. The patient was treated with gemfibrozil (Lopid...

journal_title：Journal of the American Academy of Dermatology

authors： Teltscher J,Silverman RA,Stork J

更新日期：1989-11-01 00:00:00

abstract：:Thrombocytopenia was observed in 3 patients with cutaneous angiosarcoma of the scalp and face. A sudden decrease in the platelet count occurred in association with rapid enlargement of primary or metastatic lesions. Neither antiplatelet antibody nor platelet-associated IgG was detected. Increased serum levels of beta-...

journal_title：Journal of the American Academy of Dermatology

authors： Satoh T,Takahashi Y,Yokozeki H,Katayama I,Nishioka K

更新日期：1999-05-01 00:00:00

abstract：BACKGROUND:Several studies have found that the microbiota of psoriatic lesions is different from that of healthy skin. OBJECTIVE:To characterize the microbiota of lesional and unaffected skin in patients with psoriasis and controls and investigate the correlation between cutaneous microbiota and clinical features of p...

journal_title：Journal of the American Academy of Dermatology

authors： Quan C,Chen XY,Li X,Xue F,Chen LH,Liu N,Wang B,Wang LQ,Wang XP,Yang H,Zheng J

更新日期：2020-04-01 00:00:00

abstract：:Many cutaneous diseases have been reported in patients with human immunodeficiency virus infection. We report two patients with pityriasis rubra pilaris and human immunodeficiency virus infection. In one patient, the onset of pityriasis rubra pilaris preceded the discovery of human immunodeficiency virus infection. In...

journal_title：Journal of the American Academy of Dermatology

authors： Blauvelt A,Nahass GT,Pardo RJ,Kerdel FA

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:The reported efficacy of imiquimod for lentigo maligna varies widely, without consensus on tumor or treatment factors that can impact tumor clearance. OBJECTIVE:We sought to provide a more precise estimate of clearance rates in patients with lentigo maligna who are treated with imiquimod and to analyze fact...

journal_title：Journal of the American Academy of Dermatology

authors： Mora AN,Karia PS,Nguyen BM

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Increasing incidence and mortality rates from cutaneous melanoma are a major public health concern. As part of a national effort to enhance early detection of melanoma/skin cancer, the American Academy of Dermatology (AAD) has sponsored an annual education and early detection program that couples provision o...

journal_title：Journal of the American Academy of Dermatology

authors： Koh HK,Norton LA,Geller AC,Sun T,Rigel DS,Miller DR,Sikes RG,Vigeland K,Bachenberg EU,Menon PA,Billon SF,Goldberg G,Scarborough DA,Ramsdell WM,Muscarella VA,Lew RA

更新日期：1996-06-01 00:00:00

abstract：:As a wider variety of organisms are being identified in superficial fungal infections, more accurate methods of identification may be required to determine fungal susceptibility. The sensitivity of available methods, such as the minimal inhibitory concentration test, is reviewed. The sensitivities of causative pathoge...

journal_title：Journal of the American Academy of Dermatology

authors： Meinhof W

更新日期：1993-07-01 00:00:00

abstract：:A woman with pemphigus vulgaris was treated by plasma exchange. Four separate exchanges of approximately 4,000 ml each were performed over a 2-week period. The patient's pemphigus antibody titer decreased from 1/320 before the first exchange to 1/20 after the final exchange, and no new lesions developed for 3 weeks fo...

journal_title：Journal of the American Academy of Dermatology

authors： Swanson DL,Dahl MV

更新日期：1981-03-01 00:00:00

abstract：:This review focuses on some of the most common classes of parenteral and inhalational sedating agents used during cutaneous surgery. Emphasis also is placed on potential adverse effects and their treatments. ...

journal_title：Journal of the American Academy of Dermatology

authors： Weber PJ,Weber M,Dzubow LM

更新日期：1989-05-01 00:00:00

abstract：:In addition to being recognized as a chronic inflammatory disease that manifests in the skin, psoriasis is increasingly understood to be a systemic disease that causes immune dysregulation throughout the body. The systemic nature of psoriasis is evidenced by the higher burden of comorbidities and shorter life expectan...

journal_title：Journal of the American Academy of Dermatology

authors： Lockshin B,Balagula Y,Merola JF

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:Embryofetal developmental toxicity associated with oral administration of vitamin A analogs has led to concern about risks from topical application. OBJECTIVE:This study was conducted to evaluate the potential developmental toxicity of tretinoin emollient cream when applied to the skin of pregnant New Zeala...

journal_title：Journal of the American Academy of Dermatology

authors： Christian MS,Mitala JJ,Powers WJ Jr,McKenzie BE,Latriano L

更新日期：1997-03-01 00:00:00

abstract：:Chronic mucocutaneous candidiasis is a complex disorder in which patients have chronic and recurrent Candida albicans infections of the skin, nails, and mucous membranes. There are several subgroups of patients with chronic mucocutaneous candidiasis, and these can be identified by associated disorders such as autoimmu...

journal_title：Journal of the American Academy of Dermatology

authors： Kirkpatrick CH

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND:There are subgroups of cutaneous squamous cell carcinoma (SCC) that have a higher risk for both regional and distant metastasis. When cutaneous SCC does metastasize, it typically spreads first to local nodal groups. Sentinel lymph node (SLN) localization has been successfully used to evaluate nodal metastasi...

journal_title：Journal of the American Academy of Dermatology

authors： Weisberg NK,Bertagnolli MM,Becker DS

更新日期：2000-09-01 00:00:00

abstract：:A group of 420 neonates underwent total cutaneous and oral mucosal examinations during the first week of life. Skin lesions were seen in almost every baby (99.3%). The eight most common dermatoses were desquamation (65.0%), Epstein's pearls (56.0%), sebaceous hyperplasia (48.0%), milia (36%), toxic erythema (34.8%), s...

journal_title：Journal of the American Academy of Dermatology

authors： Rivers JK,Frederiksen PC,Dibdin C

更新日期：1990-07-01 00:00:00

abstract：BACKGROUND:Despite improvements in melanoma mortality, disparities in melanoma survival persist. We evaluated possible sociodemographic and health care-based predictors of differences in melanoma survival in the United States by using the melanoma mortality-to-incidence ratio (MIR). METHODS:State-based MIRs were calcu...

journal_title：Journal of the American Academy of Dermatology

authors： Hopkins ZH,Moreno C,Carlisle R,Secrest AM

更新日期：2019-05-01 00:00:00

abstract：:Hirsutism in women is frequently associated with increased levels of androgens. Studies of biochemical changes, however, have yielded conflicting results. This study compares the findings in 30 hirsute women with normal menses and those of 30 hirsute women with abnormal cycles. Of the women with abnormal menstruation,...

journal_title：Journal of the American Academy of Dermatology

authors： Redmond GP,Bergfeld W,Gupta M,Bedocs NM,Skibinski C,Gidwani G

更新日期：1990-01-01 00:00:00

abstract：:A fatal case of transfusion-associated graft-versus-host disease developed in a premature infant after receiving several blood products, including nonirradiated white blood cells. Transfusion-associated graft-versus-host disease can be prevented. Irradiation of blood products is the least controversial and most effect...

journal_title：Journal of the American Academy of Dermatology

authors： Berger RS,Dixon SL

更新日期：1989-05-01 00:00:00

abstract：:Direct-to-consumer teledermatology is radically changing the way some patients obtain dermatologic care. Many direct-to-consumer teledermatology services offer care to patients younger than 18 years, but policies and standards are nonuniform. For pediatric patients, direct-to-consumer teledermatology is a substantial ...

journal_title：Journal of the American Academy of Dermatology

authors： Fogel AL,Teng J,Sarin KY

更新日期：2016-11-01 00:00:00

abstract：:This report describes a 25-year-old white woman with lentigines, cutaneous myxomas, bilateral atrial myxomas, and cerebral artery aneurysms. We believe this case to be the fifth reported case of this unusual association in the medical literature, with the additional finding of a central nervous system aneurysm. In the...

journal_title：Journal of the American Academy of Dermatology

authors： Reed OM,Mellette JR Jr,Fitzpatrick JE

更新日期：1986-08-01 00:00:00

abstract：:Twenty undifferentiated skin tumors were examined by immunostaining in an attempt to achieve more precise identification. Light microscopy yielded only a differential diagnosis, whereas immunostaining of formalin-fixed, paraffin-embedded tissue sections with a panel of antibodies to intermediate filaments and other ce...

journal_title：Journal of the American Academy of Dermatology

authors： Kahn H,Baumal R,From L

更新日期：1986-06-01 00:00:00

abstract：BACKGROUND:Safety profiles of systemic biologic agents for the treatment of psoriasis and psoriatic arthritis (PsA) encompass a wide spectrum of adverse events. To date, no uniform evidence-based guidelines exist regarding screening and monitoring patients who are undergoing biologic therapy. OBJECTIVE:We sought to id...

journal_title：Journal of the American Academy of Dermatology

authors： Ahn CS,Dothard EH,Garner ML,Feldman SR,Huang WW

更新日期：2015-09-01 00:00:00

abstract：BACKGROUND:There is limited data on zoster recurrence. OBJECTIVE:To examine in detail zoster recurrence in a population-based cohort. METHODS:Using data from a large cohort (The 45 and Up Study) with linked medical data (2004-2015), the incidence of first and recurrent zoster was examined using survival analyses meth...

journal_title：Journal of the American Academy of Dermatology

authors： Qian J,Macartney K,Heywood AE,Sheridan S,Liu B

更新日期：2020-07-02 00:00:00

abstract：:Disseminated histoplasmosis is being diagnosed more frequently in persons infected with the human immunodeficiency virus and is often the initial manifestation of the acquired immunodeficiency syndrome (AIDS). Disease-related cutaneous features of HIV-associated disseminated histoplasmosis are defined as mucocutaneous...

journal_title：Journal of the American Academy of Dermatology

authors： Cohen PR,Bank DE,Silvers DN,Grossman ME

更新日期：1990-09-01 00:00:00

abstract：:Metastasis to the skin from cervical carcinoma is relatively uncommon. Herein we present a 41-year-old woman with a history of cervical carcinoma with severe facial erythematous swelling and telangiectasia. She was initially treated for cellulitis without improvement. A skin biopsy specimen revealed widespread intrava...

journal_title：Journal of the American Academy of Dermatology

authors： Yang HI,Lee MC,Kuo TT,Hong HS

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Eosinophilic myositis/perimyositis (EM/P) are a group of rare idiopathic muscle disorders associated with eosinophilia. OBJECTIVE:We describe the frequency and spectrum of cutaneous manifestations in EM/P and compare them with the idiopathic hypereosinophilic syndrome (HES). METHODS:We review the literatur...

journal_title：Journal of the American Academy of Dermatology

authors： Trüeb RM,Pericin M,Winzeler B,Wüthrich B,Burg G

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Kaposi's varicelliform eruption (KVE), first described in 1887 by Moritz Kaposi, refers to a disseminated cutaneous infection with herpesvirus type 1 or 2, vaccinia virus, or coxsackievirus A16 in a patient with another underlying dermatosis. When herpesvirus type 1 or 2 is the pathogenic virus, the term "ec...

journal_title：Journal of the American Academy of Dermatology

authors： Santmyire-Rosenberger BR,Nigra TP

更新日期：2005-07-01 00:00:00

abstract：:A 39-year-ole man developed edema and vesiculation of the oral mucosa following the application of benzocaine (Hurricaine) gel. Open testing demonstrated an immediate urticarial reaction. Closed patch tests were positive after 48 hours. The contact dermatitis was consistent with a delayed-type hypersensitivity. It app...

journal_title：Journal of the American Academy of Dermatology

authors： Ryan ME,Davis BM,Marks JG Jr

更新日期：1980-03-01 00:00:00

abstract：:Cicatricial pemphigoid is an autoimmune bullous disease that has a predilection for mucous membranes and often results in scarring. We describe a case of cicatricial pemphigoid with severe involvement of the glans penis, which, despite systemic therapy, led to phimosis. ...

journal_title：Journal of the American Academy of Dermatology

authors： Fueston JC,Adams BB,Mutasim DF

更新日期：2002-05-01 00:00:00

abstract：:Incontinentia pigmenti is a rare genodermatosis of unknown etiology. A female infant with features typical of this disease was found to have basophils in early vesicular lesions. Mediators from these cells may be responsible for the accumulation of eosinophils in these lesions. ...

journal_title：Journal of the American Academy of Dermatology

authors： Schmalstieg FC,Jorizzo JL,Tschen J,Subrt P

更新日期：1984-02-01 00:00:00