Acral localized acquired cutis laxa.

abstract：BACKGROUND:In response to the increasing rate of skin cancer, particularly melanoma in the United States, the Environmental Protection Agency, the National Weather Service, the Centers for Disease Control and Prevention, National Association of Physicians for the Environment, and the American Academy of Dermatology, de...

journal_title：Journal of the American Academy of Dermatology

authors： Geller AC,Hufford D,Miller DR,Sun T,Wyatt SW,Reilley B,Bewerse B,Lisco J,Brooks D,Grupenhoff J,Weary P,Lew RA,Koh HK

更新日期：1997-12-01 00:00:00

abstract：:Disseminated histoplasmosis is being diagnosed more frequently in persons infected with the human immunodeficiency virus and is often the initial manifestation of the acquired immunodeficiency syndrome (AIDS). Disease-related cutaneous features of HIV-associated disseminated histoplasmosis are defined as mucocutaneous...

journal_title：Journal of the American Academy of Dermatology

authors： Cohen PR,Bank DE,Silvers DN,Grossman ME

更新日期：1990-09-01 00:00:00

abstract：:Hyperpigmentation of the skin is often refractory to conventional therapies, but has significant cosmetic implications if located on visible areas. Because laser systems are capable of removing pigment deposits caused by selective photothermolysis, we addressed the issue of whether the Q-switched ruby laser could be a...

journal_title：Journal of the American Academy of Dermatology

authors： Becker-Wegerich PM,Kuhn A,Malek L,Lehmann P,Megahed M,Ruzicka T

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Clusters of rare cylindroma or spiradenoma tumors are a recurrent clinical presentation, yet conventional genetic testing results in individuals with these tumors are frequently normal. OBJECTIVE:To determine if genetic mosaicism accounts for such cases. METHODS:A study of 6 cases from a series of 55 patie...

journal_title：Journal of the American Academy of Dermatology

authors： Arefi M,Wilson V,Muthiah S,Zwolinski S,Bajwa D,Brennan P,Blasdale K,Bourn D,Burn J,Santibanez-Koref M,Rajan N

更新日期：2019-12-01 00:00:00

abstract：:Subungual Bowen's disease and squamous cell carcinoma are not as rare as has been implied by earlier literature. The course of the lesions is protracted. Clinically the diseases may mimic onychomycosis, chronic paronychia, eczema, verruca vulgaris, pyogenic granuloma, subungual exostosis, or malignant melanoma. Histol...

journal_title：Journal of the American Academy of Dermatology

authors： Mikhail GR

更新日期：1984-08-01 00:00:00

abstract：:Nodular primary localized cutaneous amyloidosis is an uncommon disorder for which there is no consistently satisfactory treatment. The amyloid fibrils are thought to have an immunoglobulin light chain derivation and systemic involvement must be excluded in all cases. We report a patient with a large scalp lesion of no...

journal_title：Journal of the American Academy of Dermatology

authors： Truhan AP,Garden JM,Roenigk HH Jr

更新日期：1986-06-01 00:00:00

abstract：:Since first reported in 1982, published anecdotal reports have appeared with increasing frequency of patients in whom autoimmune connective tissue diseases developed after mammary augmentation with silicone gel-filled elastomer envelope-type prostheses. Although scleroderma has been reported most often, other diagnose...

journal_title：Journal of the American Academy of Dermatology

authors： Houpt KR,Sontheimer RD

更新日期：1994-10-01 00:00:00

abstract：:A patient is described who developed sore throat, palpable purpura, and a distinctive panniculitis. The pathologic alterations in the subcutis were similar to what Wells described in the dermis as eosinophilic cellulitis. In our experience the presence of such a picture primarily in the subcutis is unique. Streptococc...

journal_title：Journal of the American Academy of Dermatology

authors： Burket JM,Burket BJ

更新日期：1985-01-01 00:00:00

abstract：:We describe a patient with hypereosinophilic syndrome, who had severe cutaneous eruptions. Immunohistochemical study revealed that dermal endothelial cells in the lesional skin of this patient expressed eotaxin, which indicates eotaxin plays a part in inducing eosinophil migration into cutaneous tissue in hypereosinop...

journal_title：Journal of the American Academy of Dermatology

authors： Tsunemi Y,Idezuki T,Nakamura K,Tamaki K

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:The difficulties in accurately assessing pigmented skin lesions are ever present in practice. The recently described ABCD rule of dermatoscopy (skin surface microscopy at x10 magnification), based on the criteria asymmetry (A), border (B), color (C), and differential structure (D), improved diagnostic accura...

journal_title：Journal of the American Academy of Dermatology

authors： Nachbar F,Stolz W,Merkle T,Cognetta AB,Vogt T,Landthaler M,Bilek P,Braun-Falco O,Plewig G

更新日期：1994-04-01 00:00:00

abstract：:A 65-year-old man with insulin-dependent diabetes developed intractable pruritus preceding weight loss and increasing fatiguability. Esophagogastroduodenoscopy revealed infection with Candida, cytomegalovirus, and Cryptosporidium. His T cell helper/suppressor ratio was inverted, and the serum human immunodeficiency vi...

journal_title：Journal of the American Academy of Dermatology

authors： Shapiro RS,Samorodin C,Hood AF

更新日期：1987-05-01 00:00:00

abstract：LEARNING OBJECTIVES:At the conclusion of this learning activity, physician participants should be able to assess their own diagnostic and patient management skills and use the results of this exercise to help determine personal learning needs. Instructions: In answering each question, refer to the specific directions p...

journal_title：Journal of the American Academy of Dermatology

authors： Hung CT,Wang WM

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The development of autoimmune sequelae is one of the characteristic features of drug reaction with eosinophilia and systemic symptoms (DRESS) or drug-induced hypersensitivity syndrome; however, the incidence of sequelae and prognosis of patients with DRESS are unknown. OBJECTIVE:We sought to investigate the...

journal_title：Journal of the American Academy of Dermatology

authors： Chen YC,Chang CY,Cho YT,Chiu HC,Chu CY

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Pigmented Spitz nevi have distinct clinical features but often may be difficult to differentiate from malignant melanoma by clinical criteria. OBJECTIVE:The purpose of this study was to use a new noninvasive diagnostic approach to improve the clinical diagnosis of Spitz nevi. METHODS:Epiluminescence micros...

journal_title：Journal of the American Academy of Dermatology

authors： Steiner A,Pehamberger H,Binder M,Wolff K

更新日期：1992-11-01 00:00:00

abstract：:The 3 major features of psoriasis--abnormal differentiation of keratinocytes, hyperproliferation of keratinocytes, and infiltration of inflammatory components into the skin--can be quantified by measuring levels of certain biochemical markers. Psoriasis is associated with upregulation or downregulation of several of t...

journal_title：Journal of the American Academy of Dermatology

authors： Duvic M,Asano AT,Hager C,Mays S

更新日期：1998-10-01 00:00:00

abstract：:The evaluation of skin findings is critical in identifying many types of injury, whether self- inflicted or accidentally or intentionally inflicted. Specific causes of injury include homicide, abuse, neglect, assault, self-inflicted injury, suicide, torture, poisoning, and bioterrorism. Forensic findings in hair and n...

journal_title：Journal of the American Academy of Dermatology

authors： Reddy K,Lowenstein EJ

更新日期：2011-05-01 00:00:00

abstract：:We are reporting the third case of the Olmsted syndrome, an entity that has received little attention in the medical literature. The syndrome consists of congenital diffuse, sharply marginated keratoderma of the palms and soles, onychodystrophy , constrictions of digits, and periorificial keratoses. Our patient, in ad...

journal_title：Journal of the American Academy of Dermatology

authors： Poulin Y,Perry HO,Muller SA

更新日期：1984-04-01 00:00:00

abstract：:We reviewed all cases of malignant melanoma in children younger than 17 years of age who were evaluated at Sainte Justine Hospital, a tertiary care pediatric center, between 1980 and 2002. The medical records and histologic features of all cases were reviewed. Thirteen cases were identified, 4 boys and 9 girls. Fifty-...

journal_title：Journal of the American Academy of Dermatology

authors： Jafarian F,Powell J,Kokta V,Champagne M,Hatami A,McCuaig C,Marcoux D,Savard P

更新日期：2005-11-01 00:00:00

abstract：:The main limitation for the use of direct immunofluorescence in skin biopsies was the necessity for frozen tissue. In 1973 Michel et al reported use of a liquid fixative, consisting of ammonium sulfate, N-ethyl-maleimide, magnesium sulfate, and potassium citrate, for handling skin biopsy specimens. The present study i...

journal_title：Journal of the American Academy of Dermatology

authors： Niedecken HW,Lange CE

更新日期：1985-05-01 00:00:00

abstract：BACKGROUND:Early studies using HIV protease inhibitors (PI) showed regression of Kaposi's sarcoma (KS) lesions in some patients. OBJECTIVE:Our purpose was to determine prospectively the influence of PI on HIV-related KS. METHODS:KS lesions of nine patients with progressive cutaneous disease were prospectively evaluat...

journal_title：Journal of the American Academy of Dermatology

authors： Krischer J,Rutschmann O,Hirschel B,Vollenweider-Roten S,Saurat JH,Pechère M

更新日期：1998-04-01 00:00:00

abstract：:A set of three comparison studies under varying conditions was performed to determine the efficacy of a cotton swab technic for obtaining material for culture of dermatophyte infections. Matched fungal cultures, one by swab and one by scrape, on each of 110 subjects showed that there was no difference in the two metho...

journal_title：Journal of the American Academy of Dermatology

authors： Head ES,Henry JC,Macdonald EM

更新日期：1984-11-01 00:00:00

abstract：:This study was designed to investigate the relationship between alteration of skin surface pH and the development of skin irritation. Application of a phosphate/borate/acetate buffer adjusted to pH 4.0-10.5 in a standard chamber irritation test did not result in significant clinical irritation. This was true in spite ...

journal_title：Journal of the American Academy of Dermatology

authors： Murahata RI,Toton-Quinn R,Finkey MB

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:There are large discrepancies in reported mortality for bullous pemphigoid (BP). OBJECTIVE:We sought to determine the mortality of a large cohort of patients with BP and compare this with age-matched control subjects. METHODS:Data were collected on 223 patients with a new diagnosis of BP between 1998 and 2...

journal_title：Journal of the American Academy of Dermatology

authors： Parker SR,Dyson S,Brisman S,Pennie M,Swerlick RA,Khan R,Manos S,Korman BD,Xia Z,Korman NJ

更新日期：2008-10-01 00:00:00

abstract：:Aquagenic urticaria is a rare disorder characterized by the occurrence of pruritus and wheals after temporary contact with water. The familial occurrence of aquagenic urticaria over 3 generations is reported here in association with familial lactose intolerance, a condition in which the enzyme lactase encoded on chrom...

journal_title：Journal of the American Academy of Dermatology

authors： Treudler R,Tebbe B,Steinhoff M,Orfanos CE

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:The Food and Drug Administration (FDA) has received reports of depression and suicide in patients treated with isotretinoin. OBJECTIVE:Our purpose was to provide the number and describe the cases of depression and suicide reported to the FDA in US patients treated with isotretinoin and to consider the natur...

journal_title：Journal of the American Academy of Dermatology

authors： Wysowski DK,Pitts M,Beitz J

更新日期：2001-10-01 00:00:00

abstract：:Cutaneous T-cell lymphoma is a malignancy of T cells that express a clone-specific heterodimer T-cell receptor for antigen. The second recognized case of an epidermotropic malignancy of T-cells expressing gamma/delta T-cell receptor-expressing cells is reported. The immunophenotype of the malignant T-cells was CD3+, C...

journal_title：Journal of the American Academy of Dermatology

authors： Heald P,Buckley P,Gilliam A,Perez M,Knobler R,Kacinski B,Edelson R

更新日期：1992-05-01 00:00:00

abstract：:This case describes an unusual presentation of dermatomyositis in a patient with ovarian carcinoma. The eruption appeared as a venous stasislike dermatitis. The temporal sequence of onset after chemotherapy administration suggested a possible drug-induced process. However, in the context of underlying ovarian carcinom...

journal_title：Journal of the American Academy of Dermatology

authors： Seidler AM,Wasserman DI,González-Serva A,Konnikov N

更新日期：2008-09-01 00:00:00

abstract：:The role of estrogens in the development of skin cancer is controversial. Sex steroids have a profound effect on the epidermis and epidermal appendages. Estradiol in pharmacologic doses has been reported to stimulate basal cell carcinoma in an animal model. Sex hormones act by means of a specific protein receptor. In ...

journal_title：Journal of the American Academy of Dermatology

authors： Rogers GS,Flowers JL,Pollack SV,McCarty KS Jr

更新日期：1988-05-01 00:00:00

abstract：BACKGROUND:The autoantibody-mediated disease in fogo selvagem (FS) is aggravated by sunlight exposure. OBJECTIVE:The aim of this study was to test whether UVB exposure of uninvolved skin of patients with FS (n = 21) enhances epidermal acantholysis and in vivo binding of FS autoantibodies as compared with a control gro...

journal_title：Journal of the American Academy of Dermatology

authors： Reis VM,Toledo RP,Lopez A,Diaz LA,Martins JE

更新日期：2000-04-01 00:00:00

abstract：:We performed a 22-month trial of topical tretinoin (retinoic acid) in the treatment of photoaging. Thirty patients participated in a 4-month, randomized, blinded, vehicle-controlled study that has been reported previously; 21 patients continued tretinoin therapy on an open-label basis, participating in the study for a...

journal_title：Journal of the American Academy of Dermatology

authors： Ellis CN,Weiss JS,Hamilton TA,Headington JT,Zelickson AS,Voorhees JJ

更新日期：1990-10-01 00:00:00