Determination of sex steroid receptor in human basal cell carcinoma.

abstract：:Cryosurgery is a commonly used modality for treatment of benign and malignant lesions in dermatology. Although cryosurgery has been used for treatment of actinic keratoses, to our knowledge there have been no published reports on actual cure rates. This article presents a cryosurgical technic for treatment of actinic ...

journal_title：Journal of the American Academy of Dermatology

authors： Lubritz RR,Smolewski SA

更新日期：1982-11-01 00:00:00

abstract：:Our case series report is the first documented depiction of the appearance of aphthous ulcers secondary to imiquimod application. This case series presentation discusses the underlying pathophysiology of aphthous ulcer development and imiquimod therapy in terms of the stimulation of proinflammatory cytokines, such as ...

journal_title：Journal of the American Academy of Dermatology

authors： Chakrabarty AK,Mraz S,Geisse JK,Anderson NJ

更新日期：2005-02-01 00:00:00

abstract：:Hutchinson's sign, periungual extension of brown-black pigmentation from longitudinal melanonychia onto the proximal and lateral nailfolds, is an important indicator of subungual melanoma. However, experience has demonstrated that Hutchinson's sign, although valuable, is not an infallible predictor of melanoma. Periun...

journal_title：Journal of the American Academy of Dermatology

authors： Baran R,Kechijian P

更新日期：1996-01-01 00:00:00

abstract：:Granuloma annulare typically affects the hands and the feet, sparing the volar surfaces. A case of granuloma annulare localized to the palms is described. ...

journal_title：Journal of the American Academy of Dermatology

authors： Hsu S,Lehner AC,Chang JR

更新日期：1999-08-01 00:00:00

abstract：:In addition to the naturally occurring, physical, and systemic photoprotective agents reviewed in part I, topical ultraviolet radiation filters are an important cornerstone of photoprotection. Sunscreen development, efficacy, testing, and controversies are reviewed in part II of this continuing medical education artic...

journal_title：Journal of the American Academy of Dermatology

authors： Jansen R,Osterwalder U,Wang SQ,Burnett M,Lim HW

更新日期：2013-12-01 00:00:00

abstract：:Renewed interest in experimental photocarcinogenesis was stimulated by the observation that skin cancers induced in mice by ultraviolet radiation are highly antigenic. Most of these cancers are rejected by the immune system on transplantation into a normal, genetically identical animal. This finding raised the questio...

journal_title：Journal of the American Academy of Dermatology

authors： Kripke ML

更新日期：1986-01-01 00:00:00

abstract：:A patient who had pemphigus vulgaris received therapy with gold thiomalate in addition to dexamethasone. Three weeks after the initiation of parenteral gold the patient developed acute hepatitis. Causes other than gold toxicity were ruled out, and the patient recovered completely after discontinuation of gold therapy....

journal_title：Journal of the American Academy of Dermatology

authors： Rye B,Krusinski PA

更新日期：1993-01-01 00:00:00

abstract：:The number of cases of mycotic infections are increasing, presenting physicians today with an unprecedented challenge in handling the treatment and prophylactic control of these disorders. The increase in mycotic disorders is due to many factors, such as longer life span, organ transplantation, and the acquired immuno...

journal_title：Journal of the American Academy of Dermatology

authors： Jacobs PH

更新日期：1990-09-01 00:00:00

abstract：:Collodion baby is an uncommon clinical presentation of several genetic conditions, primarily disorders of cornification. The severely compromised epidermal barrier presents the greatest challenge during the newborn period and advances in neonatal care have significantly improved the prognosis. This review summarizes t...

journal_title：Journal of the American Academy of Dermatology

authors： Prado R,Ellis LZ,Gamble R,Funk T,Arbuckle HA,Bruckner AL

更新日期：2012-12-01 00:00:00

abstract：:In a pilot study the therapeutic effect and side effect profile of low-dose interferon alfa-2b in combination with a retinoid for the treatment of cutaneous T cell lymphoma were evaluated. Seven patients (four women, three men) with histologically confirmed cutaneous T cell lymphoma were included. Four patients had re...

journal_title：Journal of the American Academy of Dermatology

authors： Knobler RM,Trautinger F,Radaszkiewicz T,Kokoschka EM,Micksche M

更新日期：1991-02-01 00:00:00

abstract：:Thirty-two patients with acne completed a randomized, double-blind study using topical 1% clindamycin phosphate or its vehicle applied twice daily for 8 weeks for a study of its effects on the intestinal microflora. Two clindamycin patients and one vehicle patient had Clostridium difficile in stools prior to therapy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Siegle RJ,Fekety R,Sarbone PD,Finch RN,Deery HG,Voorhees JJ

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:Finasteride, a type II 5alpha-reductase inhibitor, reduces scalp and serum dihydrotestosterone and has been shown to be effective in men with androgenetic alopecia (AGA). OBJECTIVE:The purpose of this study was to determine the effect of finasteride on scalp hair weight in men with AGA. METHODS:Sixty-six m...

journal_title：Journal of the American Academy of Dermatology

authors： Price VH,Menefee E,Sanchez M,Ruane P,Kaufman KD

更新日期：2002-04-01 00:00:00

abstract：:We report a 38-year-old woman with lymphomatoid papulosis (LyP) who had nodular and papulovesicular lesions develop on the genital area and oral commissure. Mucosal involvement in LyP is a rare event, and its clinical relevance is still unknown. Aggressive therapies are not recommended in patients with LyP with either...

journal_title：Journal of the American Academy of Dermatology

authors： Chimenti S,Fargnoli MC,Pacifico A,Peris K

更新日期：2001-02-01 00:00:00

abstract：:Dialogues in Dermatology, a monthly audio program from the American Academy of Dermatology, contains discussions between dermatologists on timely topics. Commentaries from Dialogues Editor-in-Chief Jacqueline M. Junkins-Hopkins, MD, are provided after each discussion as a topic summary and are provided here as a speci...

journal_title：Journal of the American Academy of Dermatology

authors： Junkins-Hopkins JM

更新日期：2009-12-01 00:00:00

abstract：:Diabetic dermopathy (DD) is the most common cutaneous manifestation of diabetes mellitus. DD refers to atrophic, hyperpigmented macules characteristically located on the shins of patients with diabetes. They have an unfavorable association with the 3 most common microangiopathic complications of diabetes mellitus: neu...

journal_title：Journal of the American Academy of Dermatology

authors： Morgan AJ,Schwartz RA

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Reports suggest that cigarette smoking might interfere with the effectiveness of antimalarial therapy as first-line treatment for cutaneous lupus erythematosus. Patients refractory to this treatment often must be treated with potentially more toxic regimens. OBJECTIVE:Our purpose was to examine the effects ...

journal_title：Journal of the American Academy of Dermatology

authors： Jewell ML,McCauliffe DP

更新日期：2000-06-01 00:00:00

abstract：BACKGROUND:Many targeted therapies used in the treatment of cancer can lead to the development of xerosis, but the incidence and relative risk of xerosis have not been ascertained. OBJECTIVE:We conducted a systematic review and metaanalysis of clinical trials, to ascertain the incidence and risk of developing xerosis ...

journal_title：Journal of the American Academy of Dermatology

authors： Valentine J,Belum VR,Duran J,Ciccolini K,Schindler K,Wu S,Lacouture ME

更新日期：2015-04-01 00:00:00

abstract：:Diagnosis and classification of cutaneous lymphoid infiltrates are often hampered by lack of frozen tissue to allow detailed immunophenotyping. Therefore antibodies that recognize antigens resistant to routine tissue processing would be of value. In this study we present a detailed analysis of two such antibodies agai...

journal_title：Journal of the American Academy of Dermatology

authors： Sterry W,Hauschild A

更新日期：1989-07-01 00:00:00

abstract：:Discoid lupus erythematosus lesions show hyperkeratosis and atrophy, which may reflect abnormal epidermal proliferation, differentiation, or both. In this investigation, markers for epidermal proliferation, differentiation and inflammation were studied in cutaneous lesions of discoid lupus erythematosus. Frozen sectio...

journal_title：Journal of the American Academy of Dermatology

authors： de Jong EM,van Erp PE,Ruiter DJ,van de Kerkhof PC

更新日期：1991-12-01 00:00:00

abstract：:We report a case of fatal pancreatitis heralded by the presence of cutaneous panniculitis without abdominal pain or other stigmata of the disease. Although cutaneous fat necrosis has been associated with pancreatitis, it is unusual as the presenting complaint of this relatively common disease. In vitro evidence sugges...

journal_title：Journal of the American Academy of Dermatology

authors： Berman B,Conteas C,Smith B,Leong S,Hornbeck L 3rd

更新日期：1987-08-01 00:00:00

abstract：:Metastasis to the skin from cervical carcinoma is relatively uncommon. Herein we present a 41-year-old woman with a history of cervical carcinoma with severe facial erythematous swelling and telangiectasia. She was initially treated for cellulitis without improvement. A skin biopsy specimen revealed widespread intrava...

journal_title：Journal of the American Academy of Dermatology

authors： Yang HI,Lee MC,Kuo TT,Hong HS

更新日期：2007-02-01 00:00:00

abstract：:Infections with mycobacteria are of importance in the differential diagnosis of skin lesions in immunocompromised patients. We report the case of a human immunodeficency virus (HIV)-infected patient who presented with an annular plaque as cutaneous manifestation of Mycobacterium haemophilum. Improvement of the immunol...

journal_title：Journal of the American Academy of Dermatology

authors： Friedli A,Krischer J,Hirschel B,Saurat JH,Pechère M

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:Eosinophilic myositis/perimyositis (EM/P) are a group of rare idiopathic muscle disorders associated with eosinophilia. OBJECTIVE:We describe the frequency and spectrum of cutaneous manifestations in EM/P and compare them with the idiopathic hypereosinophilic syndrome (HES). METHODS:We review the literatur...

journal_title：Journal of the American Academy of Dermatology

authors： Trüeb RM,Pericin M,Winzeler B,Wüthrich B,Burg G

更新日期：1997-09-01 00:00:00

abstract：BACKGROUND:Excess cathelicidin and kallikrein 5 (KLK5) have been hypothesized to play a role in the pathophysiology of rosacea. OBJECTIVE:We sought to evaluate the effects of azelaic acid (AzA) on these elements of the innate immune system. METHODS:Gene expression and protease activity were measured in laboratory mod...

journal_title：Journal of the American Academy of Dermatology

authors： Coda AB,Hata T,Miller J,Audish D,Kotol P,Two A,Shafiq F,Yamasaki K,Harper JC,Del Rosso JQ,Gallo RL

更新日期：2013-10-01 00:00:00

abstract：:A patient with sarcoidosis was treated with thalidomide for disfiguring and painful steroid unresponsive sarcoidal granulomas of the skin. The duration of the therapy was 14 months, during which time, the skin lesions resolved almost completely. The initial dosage was 200 mg a day, which was increased to 400 mg a day ...

journal_title：Journal of the American Academy of Dermatology

authors： Lee JB,Koblenzer PS

更新日期：1998-11-01 00:00:00

abstract：:Hyperkeratosis of the nipple and areola is a rare condition. We report two cases of hyperkeratosis of the nipple and areola occurring in men with no underlying endocrinopathy or synthetic estrogenic drug therapy. Both patients demonstrated prompt resolution of the hyperkeratosis of the nipples with a keratolytic gel. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kuhlman DS,Hodge SJ,Owen LG

更新日期：1985-10-01 00:00:00

abstract：:Tissue resistance to insulin is a major feature underlying the development of acanthosis nigricans in many patients. We report two unusual cases of acanthosis nigricans with contrasting forms of insulin resistance and propose an algorithm for the evaluation of patients with acanthosis nigricans. Further, we present a ...

journal_title：Journal of the American Academy of Dermatology

authors： Rendon MI,Cruz PD Jr,Sontheimer RD,Bergstresser PR

更新日期：1989-09-01 00:00:00

abstract：:The acute complications that may result in failure of the surgical procedure are discussed. These include bleeding, hematoma, infection, dehiscence, and necrosis. The background of each is covered in detail and an attempt is made to show the interrelationships among them. The purpose of this communication is to aid in...

journal_title：Journal of the American Academy of Dermatology

authors： Salasche SJ

更新日期：1986-12-01 00:00:00

abstract：:We describe a new family with the rare genodermatosis keratosis punctata palmo-plantaris Buschke-Fischer-Brauer (keratoma disseminatum). In all, 3 family members in 3 generations were affected, a pattern consistent with autosomal dominant inheritance. Clinical symptoms started in the third decade with disseminated, sm...

journal_title：Journal of the American Academy of Dermatology

authors： Emmert S,Küster W,Zutt M,Hänssle H,Hallermann C,Kretschmer L,Neumann C

更新日期：2003-12-01 00:00:00

abstract：:Pain is a central component of illness and suffering, yet unfortunately it is frequently undertreated. In dermatology, many acute and chronic conditions are characterized by pain that may require therapeutic intervention in addition to medical treatment aimed at treating the primary disease. To date, however, there ar...

journal_title：Journal of the American Academy of Dermatology

authors： Enamandram M,Rathmell JP,Kimball AB

更新日期：2015-10-01 00:00:00