Abstract:
BACKGROUND:There are large discrepancies in reported mortality for bullous pemphigoid (BP). OBJECTIVE:We sought to determine the mortality of a large cohort of patients with BP and compare this with age-matched control subjects. METHODS:Data were collected on 223 patients with a new diagnosis of BP between 1998 and 2003 through our cutaneous immunofluorescence laboratory databases. The mortality of patients with BP was compared with that of age-matched control subjects in the general US population. RESULTS:The 1-, 2-, and 5-year mortality was 0.23 (95% confidence interval=0.18, 0.29), 0.37 (95% confidence interval=0.31, 0.44), and 0.50 (95% confidence interval=0.42, 0.57), respectively. However, relative to age-matched control subjects, no difference in expected mortality was detected. LIMITATIONS:This was a retrospective cohort analysis. CONCLUSIONS:Mortality of patients with BP is more likely related to advanced age and associated medical conditions than to disease-specific factors.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Parker SR,Dyson S,Brisman S,Pennie M,Swerlick RA,Khan R,Manos S,Korman BD,Xia Z,Korman NJdoi
10.1016/j.jaad.2008.07.022subject
Has Abstractpub_date
2008-10-01 00:00:00pages
582-8issue
4eissn
0190-9622issn
1097-6787pii
S0190-9622(08)00913-4journal_volume
59pub_type
杂志文章abstract::In addition to the naturally occurring, physical, and systemic photoprotective agents reviewed in part I, topical ultraviolet radiation filters are an important cornerstone of photoprotection. Sunscreen development, efficacy, testing, and controversies are reviewed in part II of this continuing medical education artic...
journal_title:Journal of the American Academy of Dermatology
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更新日期:2013-12-01 00:00:00
abstract::The hemophagocytic syndrome (HPS) was first described in immune-compromised patients with secondary viral infections. Immunodeficiency has not always been diagnosed before the onset of HPS, but most patients who develop HPS have known immune deficits. HPS has also been reported in association with lymphoreticular mali...
journal_title:Journal of the American Academy of Dermatology
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doi:10.1016/0190-9622(91)70284-9
更新日期:1991-11-01 00:00:00
abstract::Twenty percent of Americans will be over age 65 by 2030,1 and without a dedicated geriatrics curriculum in many residency trainings programs, dermatologists may be less familiar with age-associated side effects of common dermatologic medications. Herein, we provide a practical guide and clinical safety pearls for the ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2021.01.027
更新日期:2021-01-16 00:00:00
abstract::Minimal erythema doses (MEDs) of individuals with different skin types were compared. Each skin type was shown to be statistically different from each other skin type in terms of sunburn sensitivity. Individuals of each skin type who primarily stayed indoors were compared with those who attempted to be outdoors. In th...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(81)70106-3
更新日期:1981-10-01 00:00:00
abstract::Psychosomatic dermatology is practiced in some manner by every dermatologist. In spite of this, there has been a virtual void in the literature from the middle 1950s until the present time. The relationship to physiologic phenomena, as well as a classification of psychosomatic dermatology, is reviewed. Dermatologic pa...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/s0190-9622(81)70081-1
更新日期:1981-08-01 00:00:00
abstract:BACKGROUND:Concern has been raised about the potential long-term effects of propranolol treatment for infantile hemangioma (IH). OBJECTIVES:We sought to assess psychologic (social, emotional, behavioral, and executive) functioning in children treated with propranolol for IH. METHODS:Twenty-seven patients with IH (6.1...
journal_title:Journal of the American Academy of Dermatology
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doi:10.1016/j.jaad.2017.01.025
更新日期:2017-07-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
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doi:10.1016/j.jaad.2013.07.040
更新日期:2013-12-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(98)70370-6
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abstract::A set of three comparison studies under varying conditions was performed to determine the efficacy of a cotton swab technic for obtaining material for culture of dermatophyte infections. Matched fungal cultures, one by swab and one by scrape, on each of 110 subjects showed that there was no difference in the two metho...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(84)80455-7
更新日期:1984-11-01 00:00:00
abstract::We report the case of an 84-year-old white male who underwent vermilionectomy for removal of a tumor, which proved to be squamous cell carcinoma. Chelitis glandularis related to marked actinic damage was noted at a subsequent visit. The presence of chelitis glandularis should be investigated for the presence of neopla...
journal_title:Journal of the American Academy of Dermatology
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abstract:BACKGROUND:Complications associated with psoriatic arthritis (PsA) may be prevented with early diagnosis and initiation of therapy. Up to one third of psoriasis patients may have PsA. There is a need to screen psoriasis patients early for symptoms of PsA. OBJECTIVE:To develop and validate a patient self-administered t...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2007.04.001
更新日期:2007-10-01 00:00:00
abstract::Scleromyxedema is a rare fibromucinous connective tissue that can be associated with systemic changes, such as myopathy, neurologic defects, esophageal dysmotility, paraproteinemia, and restrictive lung disease. We describe a fatal case of scleromyxedema in which neurologic, cardiac, gastrointestinal, and muscle chang...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/s0190-9622(98)70567-5
更新日期:1998-02-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
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doi:10.1016/s0190-9622(87)70056-5
更新日期:1987-02-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
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doi:10.1016/0190-9622(90)70342-f
更新日期:1990-12-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
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doi:10.1016/s0190-9622(99)70119-2
更新日期:1999-09-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2008.10.001
更新日期:2009-05-01 00:00:00
abstract::A 52-year-old man with a history of melanoma presented to the emergency department with a massive intracranial hemorrhage. The patient deteriorated rapidly and was being considered as a potential organ donor. Three years before presentation, the patient had undergone wide excision of a 3.75-mm melanoma from his back w...
journal_title:Journal of the American Academy of Dermatology
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doi:10.1016/j.jaad.2006.02.064
更新日期:2006-06-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(85)70072-2
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journal_title:Journal of the American Academy of Dermatology
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journal_title:Journal of the American Academy of Dermatology
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journal_title:Journal of the American Academy of Dermatology
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doi:10.1016/j.jaad.2014.03.032
更新日期:2014-08-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2005.10.041
更新日期:2006-04-01 00:00:00
abstract::Ticks are ectoparasites that cause dermatologic disease directly by their bite and indirectly as vectors of bacterial, rickettsial, protozoal, and viral diseases. In North America, where ticks are the leading cause of vector-borne infection, dermatologists should recognize several tick species. Basic tick biology and ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
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更新日期:2003-09-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(96)90323-0
更新日期:1996-08-01 00:00:00
abstract::Since proteolytic processes are prominent in psoriasis, sera of forty-five psoriatics were examined for alpha 1-antitrypsin (alpha 1-AT) phenotype and eighteen sera, for alpha 1-AT content and function. Five sera (11.1%) had heterozygous phenotypes (2 MZ and 3 MS), a prevalence of Z and S variants similar to that repo...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(84)70216-7
更新日期:1984-10-01 00:00:00
abstract::Immunopathology continues to be important in diagnostic dermatopathology. Immunopathology is an invaluable tool for assessing the tissue of origin or direction of differentiation of cells. In some cases this can result in a more precise diagnosis. This article reviews the role of immunopathology in determining the bio...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/s0190-9622(96)80106-x
更新日期:1996-02-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2014.09.012
更新日期:2014-12-01 00:00:00
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journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(93)70273-v
更新日期:1993-12-01 00:00:00
abstract::A case of phaeohyphomycosis caused by Phialophora richardsiae is presented. The patient was a 30-year-old man with end stage malignant lymphoma. A subcutaneous abscess that developed on the dorsum of the right foot was removed surgically but immediately recurred. The causative mold was isolated from the pus in the les...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(88)70200-5
更新日期:1988-09-01 00:00:00
abstract::A 65-year-old woman treated with etretinate for pityriasis rubra pilaris developed chronic active hepatitis. The elevated transaminases were noted 2 months after initiation of therapy and peaked 2 months after discontinuation of etretinate. The spectrum of liver toxicity induced by etretinate is reviewed. We suggest t...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/0190-9622(93)70117-c
更新日期:1993-05-01 00:00:00