Mortality of bullous pemphigoid: an evaluation of 223 patients and comparison with the mortality in the general population in the United States.

Abstract:

BACKGROUND:There are large discrepancies in reported mortality for bullous pemphigoid (BP). OBJECTIVE:We sought to determine the mortality of a large cohort of patients with BP and compare this with age-matched control subjects. METHODS:Data were collected on 223 patients with a new diagnosis of BP between 1998 and 2003 through our cutaneous immunofluorescence laboratory databases. The mortality of patients with BP was compared with that of age-matched control subjects in the general US population. RESULTS:The 1-, 2-, and 5-year mortality was 0.23 (95% confidence interval=0.18, 0.29), 0.37 (95% confidence interval=0.31, 0.44), and 0.50 (95% confidence interval=0.42, 0.57), respectively. However, relative to age-matched control subjects, no difference in expected mortality was detected. LIMITATIONS:This was a retrospective cohort analysis. CONCLUSIONS:Mortality of patients with BP is more likely related to advanced age and associated medical conditions than to disease-specific factors.

journal_name

J Am Acad Dermatol

authors

Parker SR,Dyson S,Brisman S,Pennie M,Swerlick RA,Khan R,Manos S,Korman BD,Xia Z,Korman NJ

doi

10.1016/j.jaad.2008.07.022

subject

Has Abstract

pub_date

2008-10-01 00:00:00

pages

582-8

issue

4

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(08)00913-4

journal_volume

59

pub_type

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