Effect of pH on the production of irritation in a chamber irritation test.

abstract：BACKGROUND:In animal models, extracts from green tea have been shown to be remarkably effective at reducing the severity of adverse human health effects of overexposure to ultraviolet (UV) radiation. Although sunscreens and other photoprotective measures have traditionally been used for this purpose, there is a need fo...

journal_title：Journal of the American Academy of Dermatology

authors： Elmets CA,Singh D,Tubesing K,Matsui M,Katiyar S,Mukhtar H

更新日期：2001-03-01 00:00:00

abstract：:The prognosis of localized malignant melanoma is related to several histologic features of the primary lesion. Growth pattern, level of invasion, and tumor thickness are currently most widely used in clinical practice, but other features, including ulceration, mitotic rate, density of the inflammatory response, eviden...

journal_title：Journal of the American Academy of Dermatology

authors： Maize JC

更新日期：1983-06-01 00:00:00

abstract：:The diagnostic value of parakeratosis is reviewed, with special emphasis on associated inflammatory tissue reaction patterns and the geometric pattern of the scale. Parakeratosis may also occur in disorders not primarily inflammatory in nature and those associations are addressed. Topics are divided into 6 categories:...

journal_title：Journal of the American Academy of Dermatology

authors： Brady SP

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Wide-ranging prevalence estimates of psoriatic arthritis (PsA) in patients with psoriasis have been reported. OBJECTIVES:To assess the prevalence and incidence of PsA in patients with psoriasis. METHODS:Two authors independently searched 3 databases for studies reporting on the prevalence or incidence of P...

journal_title：Journal of the American Academy of Dermatology

authors： Alinaghi F,Calov M,Kristensen LE,Gladman DD,Coates LC,Jullien D,Gottlieb AB,Gisondi P,Wu JJ,Thyssen JP,Egeberg A

更新日期：2019-01-01 00:00:00

abstract：:Pyoderma gangrenosum, severe acne, and suppurative hidradenitis (PASH) syndrome can prove refractory to treatment and is characterized by relapses and recurrences. The combination of antibiotic therapy and surgery can produce success in the management of the syndrome. Acute treatment is required, but maintenance thera...

journal_title：Journal of the American Academy of Dermatology

authors： Join-Lambert O,Duchatelet S,Delage M,Miskinyte S,Coignard H,Lemarchand N,Alemy-Carreau M,Lortholary O,Nassif X,Hovnanian A,Nassif A

更新日期：2015-11-01 00:00:00

abstract：:A case is presented in which a patient experienced the development of both Dupuytren's disease and Peyronie's disease after single episodes of sports-related trauma. These disorders and other fibromatoses are linked not only by similar pathologic features but by increased frequency of simultaneous occurrence. Some gen...

journal_title：Journal of the American Academy of Dermatology

authors： Connelly TJ

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:Intertriginous and facial involvement are manifestations of psoriasis that require a different approach than is used for typical plaque psoriasis on other skin areas. Topical corticosteroids are the primary treatment for psoriasis; however, the side effects of corticosteroids are magnified on intertriginous ...

journal_title：Journal of the American Academy of Dermatology

authors： Lebwohl M,Freeman AK,Chapman MS,Feldman SR,Hartle JE,Henning A,Tacrolimus Ointment Study Group.

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Physician visits provide invaluable opportunities to screen patients for skin cancer, yielding earlier detection and improved survival. OBJECTIVE:We sought to assess frequency of skin cancer screening by full body skin examinations (FBSE) by primary care physicians, patient attitudes toward FBSE, and risk f...

journal_title：Journal of the American Academy of Dermatology

authors： Rodriguez GL,Ma F,Federman DG,Rouhani P,Chimento S,Multach M,Kirsner RS

更新日期：2007-11-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis is a common multifactorial disease that seems to be increasing in frequency. OBJECTIVE:Our purpose was to determine the increased prevalence of atopic dermatitis in North Europe. METHODS:Approximately 3000 7-year-old children in Denmark, Germany, and Sweden were enrolled in a cross-sectio...

journal_title：Journal of the American Academy of Dermatology

authors： Schultz Larsen F,Diepgen T,Svensson A

更新日期：1996-05-01 00:00:00

abstract：:The literature concerning the use and possible mode of action of thalidomide in reactional lepromatous leprosy and in various other conditions is reviewed. Although it has no action against the leprosy bacillus, its value in the treatment of the adverse reactions in this type of leprosy is well established, many lepro...

journal_title：Journal of the American Academy of Dermatology

authors： Barnhill RL,McDougall AC

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND:Tinea corporis gladiatorum has been an infrequently reported condition in the dermatological literature. Two previous reports have investigated wrestlers during recognized epidemics of tinea corporis gladiatorum, but no study has examined wrestlers to determine the point prevalence of tinea corporis gladiato...

journal_title：Journal of the American Academy of Dermatology

authors： Adams BB

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:Keloids are a common lesion arising from sites of previous trauma and are a considerable source of morbidity because of continued growth of lesions, pruritus, and physical appearance. They consist of mesenchymal cells embedded in a stroma of disordered collagen matrix. Clinically, keloids are distinguished f...

journal_title：Journal of the American Academy of Dermatology

authors： Kim A,DiCarlo J,Cohen C,McCall C,Johnson D,McAlpine B,Quinn AG,McLaughlin ER,Arbiser JL

更新日期：2001-11-01 00:00:00

abstract：:Schönlein-Henoch purpura is characterized by palpable purpura, colicky abdominal pain, gastrointestinal hemorrhage, arthralgias, and renal involvement. Bacterial and viral infections, as well as drugs and diseases associated with immune complexes, are thought to be responsible. We describe the case of a 21-year-old wo...

journal_title：Journal of the American Academy of Dermatology

authors： Reinauer S,Megahed M,Goerz G,Ruzicka T,Borchard F,Susanto F,Reinauer H

更新日期：1995-11-01 00:00:00

abstract：:Pigmentary demarcation lines are borders of abrupt transition between more deeply pigmented skin and that of lighter pigmentation. Two patients developed these lines on the lower extremities during pregnancy. ...

journal_title：Journal of the American Academy of Dermatology

authors： James WD,Meltzer MS,Guill MA,Berger TG,Rodman OG

更新日期：1984-09-01 00:00:00

abstract：:Transepithelial elimination of granulomas was observed in histologic specimens taken from involved skin of a patient with disseminated tuberculosis and two patients with sarcoidosis. This phenomenon, previously also observed in other granulomatous disorders, represents one of the skin's several mechanisms to rid itsel...

journal_title：Journal of the American Academy of Dermatology

authors： Goette DK,Odom RB

更新日期：1986-01-01 00:00:00

abstract：:Recently, a relationship between immunologic alterations and the development of lichen nitidus (LN) lesions has been described. We treated LN lesions with topical dinitrochlorobenzene (DNCB) application in a patient with peripheral CD4+ T lymphocytopenia. After 4 months, the eruption cleared. We investigated histologi...

journal_title：Journal of the American Academy of Dermatology

authors： Kano Y,Otake Y,Shiohara T

更新日期：1998-08-01 00:00:00

abstract：BACKGROUND:Molluscum contagiosum (MC) is a common and at times severely disfiguring cutaneous viral infection in patients with human immunodeficiency virus (HIV) infection. OBJECTIVE:The purpose of this study was to describe the clinical course of MC in patients with HIV infection and to examine the relation between p...

journal_title：Journal of the American Academy of Dermatology

authors： Schwartz JJ,Myskowski PL

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Spindle cell melanoma (SCM) including desmoplastic melanoma (DM) is a rare variant of malignant melanoma that may present diagnostic difficulties particularly when staining with S100 is negative, weak, focal, or a combination of these. Conventional melanocytic markers in SCM are usually negative. OBJECTIVE:...

journal_title：Journal of the American Academy of Dermatology

authors： Lazova R,Tantcheva-Poor I,Sigal AC

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Although an association between antihistaminic drugs and atypical cutaneous lymphoid infiltrates has not been reported previously, in vitro evidence suggests that these agents perturb certain lymphoid functions through binding to histamine receptors, including a novel growth-promoting intracellular histamine...

journal_title：Journal of the American Academy of Dermatology

authors： Magro CM,Crowson AN

更新日期：1995-03-01 00:00:00

abstract：:Two cases of semicircular lipoatrophy and one of annular lipoatrophy are presented. The reasons why semicircular lipoatrophy, annular lipoatrophy, and annular atrophy of the ankles seem to be different clinical entities are discussed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Rongioletti F,Rebora A

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Women with stage I malignant melanoma (MM) have a survival advantage over men as judged by univariate analysis. However, on multivariate analysis, gender was found to be an independent predictor of survival in only 8 of 14 published studies. OBJECTIVE:This study attempts to explain the disparate findings fo...

journal_title：Journal of the American Academy of Dermatology

authors： Vossaert KA,Silverman MK,Kopf AW,Bart RS,Rigel DS,Friedman RJ,Levenstein M

更新日期：1992-03-01 00:00:00

abstract：:Blue-brown macules of the face occurring on both sides of the forehead, temple, eyelids, malar area, alae of the nose, and root of the nose are often observed in middle-aged Japanese women. These lesions histologically are a form of dermal melanocytosis as shown by electron microscopic examination. They differ clinica...

journal_title：Journal of the American Academy of Dermatology

authors： Hori Y,Kawashima M,Oohara K,Kukita A

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:A wide array of miscellaneous agents is being studied for the treatment of atopic dermatitis (AD), including targeted topical, oral systemic, and biologic agents. OBJECTIVE:To review the known efficacy and safety to date for such agents being studied for the treatment of AD. METHODS:A nonsystematic review ...

journal_title：Journal of the American Academy of Dermatology

authors： Vakharia PP,Silverberg JI

更新日期：2018-03-01 00:00:00

abstract：:Kyrle's disease is a chronic, genetically determined, hyperkeratotic disorder occurring in the middle forties. We report fourteen cases of this disorder in a population of 1.5 million over a period of 15 years. We observed a female/male ratio of 6:1. Straw-colored keratotic plugs and flat scale show a marked predispos...

journal_title：Journal of the American Academy of Dermatology

authors： Cunningham SR,Walsh M,Matthews R,Fulton R,Burrows D

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Associations between gluten intake and psoriasis, psoriatic arthritis, and atopic dermatitis are poorly understood. OBJECTIVE:To determine whether increased gluten intake is associated with incident psoriasis, psoriatic arthritis, and atopic dermatitis. METHODS:Cohort studies among women in Nurses' Health ...

journal_title：Journal of the American Academy of Dermatology

authors： Drucker AM,Qureshi AA,Thompson JM,Li T,Cho E

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:There is large variability in the risk of sentinel lymph node (SLN) positivity among patients with intermediate thickness melanoma (ITM), with a subgroup of patients exhibiting a low risk of nodal disease. OBJECTIVE:To identify a group of patients with ITM for whom the risk of nodal disease is low. METHODS...

journal_title：Journal of the American Academy of Dermatology

authors： Hanna AN,Sinnamon AJ,Roses RE,Kelz RR,Elder DE,Xu X,Pockaj BA,Zager JS,Fraker DL,Karakousis GC

更新日期：2019-02-01 00:00:00

abstract：BACKGROUND:Pulsed dye laser (PDL) is the gold standard for treatment of port-wine stain (PWS) birthmarks but multiple treatments are required and complete resolution is often not achieved. Posttreatment vessel recurrence is thought to be a factor that limits efficacy of PDL treatment of PWS. Imiquimod 5% cream is an im...

journal_title：Journal of the American Academy of Dermatology

authors： Tremaine AM,Armstrong J,Huang YC,Elkeeb L,Ortiz A,Harris R,Choi B,Kelly KM

更新日期：2012-04-01 00:00:00

abstract：:The growing investigation and use of epidermal growth factor receptor (EGFR) inhibitors in anticancer therapy has been motivated by their specificity for EGFR, which improves their ability to target cancer cells and enhances their safety profile compared with many other conventional chemotherapeutic agents. However, t...

journal_title：Journal of the American Academy of Dermatology

authors： Hu JC,Sadeghi P,Pinter-Brown LC,Yashar S,Chiu MW

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Melanoma in African Americans is rare, and the diagnosis is often delayed, leading to advanced presentation and poor prognosis. OBJECTIVE:The purpose of this retrospective study is to determine whether African American patients diagnosed with melanoma at the Washington Hospital Center were initially seen wi...

journal_title：Journal of the American Academy of Dermatology

authors： Byrd KM,Wilson DC,Hoyler SS,Peck GL

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Confluent and reticulated papillomatosis (CRP) of Gougerot and Carteaud is an uncommon disorder of unknown cause for which a variety of treatments have been proposed. OBJECTIVE:We attempted to evaluate the effectiveness of oral minocycline. METHODS:Nine patients with CRP were treated with oral minocycline,...

journal_title：Journal of the American Academy of Dermatology

authors： Montemarano AD,Hengge M,Sau P,Welch M

更新日期：1996-02-01 00:00:00