Abstract:
:Schönlein-Henoch purpura is characterized by palpable purpura, colicky abdominal pain, gastrointestinal hemorrhage, arthralgias, and renal involvement. Bacterial and viral infections, as well as drugs and diseases associated with immune complexes, are thought to be responsible. We describe the case of a 21-year-old woman with Schönlein-Henoch purpura and chronic active gastritis with erosions. Helicobacter pylori was found in gastric mucosa using the newly introduced, nontoxic, noninvasive 13C-urea breath test; infection was confirmed by gastric mucosal biopsy. After eradication of H. pylori with omeprazole and amoxicillin, the skin changes, gastric complaints, and proteinuria disappeared. Ten months later, Schönlein-Henoch purpura recurred. H. pylori was again detected. After therapy, H. pylori was eradicated and the clinical manifestations faded. To our knowledge, H. pylori has not previously been described as a cause of Schönlein-Henoch purpura.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Reinauer S,Megahed M,Goerz G,Ruzicka T,Borchard F,Susanto F,Reinauer Hdoi
10.1016/0190-9622(95)90426-3subject
Has Abstractpub_date
1995-11-01 00:00:00pages
876-9issue
5 Pt 2eissn
0190-9622issn
1097-6787pii
0190-9622(95)90426-3journal_volume
33pub_type
杂志文章abstract:BACKGROUND:There is lack of studies on the diagnostic accuracy of dermatoscopy and reflectance confocal microscopy (RCM) for dark pigmented lesions. OBJECTIVE:To assess the diagnostic accuracy of dermatoscopy plus confocal microscopy for melanoma diagnosis of dark pigmented lesions in real life. METHODS:Prospective a...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2020.07.084
更新日期:2020-07-27 00:00:00
abstract:BACKGROUND:The histopathological and clinical overlapping features between condyloma acuminata and bowenoid papulosis can present a diagnostic challenge and we sought to determine if immunochemistry can be helpful in this setting. OBJECTIVE:In this study, we evaluate the specificity and sensitivity of p16 immunohistoc...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2013.04.036
更新日期:2013-09-01 00:00:00
abstract:BACKGROUND:Treatment of basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) has traditionally focused on minimizing recurrence and complication rates. However, the assessment of patient satisfaction and quality of life (QOL) is also important. These outcomes are best assessed by patient-reported outcome (PRO) ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2012.09.017
更新日期:2013-08-01 00:00:00
abstract::Sebaceous lesions are associated with two syndromes with widespread multisystem disorders and tumors. Linear sebaceous nevus syndrome has been traditionally known as the triad of sebaceous nevus of Jadassohn, seizures, and mental retardation. This syndrome encompasses a much broader spectrum of multisystem disorders, ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2009.04.059
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:Alcohol consumption and smoking have long been suspected of increasing the risk of developing psoriasis. Most evidence to date has derived from cross-sectional or case-control studies. OBJECTIVE:We sought to investigate the effects of alcohol and smoking on incident psoriasis. METHODS:Alcohol consumption, ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2018.11.015
更新日期:2019-03-01 00:00:00
abstract:BACKGROUND:Genetic and environmental risk factors have been associated with the development of multiple primary melanomas (MPM). We hypothesized that individuals with MPM may have increased predisposition to developing internal malignancies. OBJECTIVE:To identify the risk of subsequent malignancies in MPM patients. M...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2018.09.027
更新日期:2018-10-01 00:00:00
abstract::Tuberous sclerosis is characterized by epilepsy, mental retardation, and adenoma sebaceum. Computerized axial tomography (CAT) is a noninvasive laboratory test that can assist in the diagnosis of this syndrome radiologically. A positive CAT scan is often present before the calcifications are noted on skull x-rays and ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(81)70009-4
更新日期:1981-01-01 00:00:00
abstract::A case of tuberculous skin ulcer is reported. The biopsy specimen did not reveal acid-fast bacteria but cultures grew Mycobacterium tuberculosis. A high index of suspicion is needed to diagnose mycobacterial ulcers correctly. The classification of the cutaneous tuberculoses is discussed. ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(88)70274-1
更新日期:1988-12-01 00:00:00
abstract:BACKGROUND:Detection of melanoma by physicians via opportunistic surveillance during focused physical examinations may reduce mortality. Medical students may not encounter a clinical case of melanoma during a dermatology clerkship. OBJECTIVE:This study examined the proficiency of fourth-year University of Illinois at ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2011.10.032
更新日期:2013-03-01 00:00:00
abstract::The presence of mast cells, often in an activated state or increased numbers, has been noted in various cutaneous disorders. Recent studies suggest that mast cells are of primary importance in these conditions and their presence does not merely represent a secondary event. This review focuses on atopic dermatitis, con...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/0190-9622(90)70264-i
更新日期:1990-10-01 00:00:00
abstract::Acitretin, a metabolite of etretinate, was given to 38 patients for the treatment of psoriasis. During the first 8 weeks patients received either placebo, 10 mg, 25 mg, 50 mg, or 75 mg of acitretin daily in a double-blind manner. The dosages of 10 mg and 25 mg daily did not achieve any statistically significant improv...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章
doi:10.1016/s0190-9622(88)70086-9
更新日期:1988-04-01 00:00:00
abstract:BACKGROUND:Erythema induratum of Bazin is a mostly lobular panniculitis. There is considerable controversy in the literature about whether or not vasculitis is a histopathologic requirement to establish the diagnosis of erythema induratum of Bazin. Even accepting vasculitis as a histopathologic criterion, there is no a...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2008.07.030
更新日期:2008-11-01 00:00:00
abstract::We report a case of dermatomyositis presenting with cutaneous mucinosis as the sole manifestation. A malignancy screen revealed an underlying nasopharyngeal carcinoma. ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1067/mjd.2003.161
更新日期:2003-05-01 00:00:00
abstract:BACKGROUND:T-cell receptor (TCR) clonality may help establish a diagnosis of mycosis fungoides (MF). Routine clonality analysis is performed by using a polymerase chain reaction TCR- gamma assay, yet with this method, 10% to 50% of T-cell lymphomas escape detection. TCR- beta gene rearrangement is an additional assay. ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2020.05.110
更新日期:2020-11-01 00:00:00
abstract::As a prerequisite to standardization of dermatophyte susceptibility testing, conditions that support optimal growth of different dermatophyte species must be established. Eighteen isolates of Trichophyton spp. (T rubrum, T mentagrophytes, T tonsurans) were grown in 4 different media: RPMI 1640 with L-glutamine, withou...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(99)70392-0
更新日期:1999-06-01 00:00:00
abstract::The Chimila, a Colombian Amerindian group that lives at a low altitude, have a high incidence of actinic prurigo. We present the human lymphocyte antigen (HLA) findings of 43 Chimilas with the disease and of 62 control subjects and show an association of actinic prurigo with the Cw4 antigen. ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(90)70150-g
更新日期:1990-06-01 00:00:00
abstract::In a pilot study the therapeutic effect and side effect profile of low-dose interferon alfa-2b in combination with a retinoid for the treatment of cutaneous T cell lymphoma were evaluated. Seven patients (four women, three men) with histologically confirmed cutaneous T cell lymphoma were included. Four patients had re...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章
doi:10.1016/0190-9622(91)70036-2
更新日期:1991-02-01 00:00:00
abstract:BACKGROUND:Photosensitivity (PS) in lupus erythematosus (LE) is frequently determined by patient report. OBJECTIVE:We sought to characterize self-reported PS in cutaneous LE (CLE). METHODS:The PS survey was used to classify subject responses into 5 phenotypes: direct sun-induced CLE flare (directCLE); general exacerb...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2013.03.015
更新日期:2013-08-01 00:00:00
abstract::Sweet's syndrome (SS) occurs most commonly in association with inflammatory or neoplastic disorders. Only rarely has it been associated with immunodeficiency disorders. We describe a child with a T-cell immunodeficiency who had a persistent neutrophilic dermatosis that was histologically and clinically consistent with...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1053/jd.1999.v40.a95650
更新日期:1999-05-01 00:00:00
abstract:BACKGROUND:Cidofovir is a potent nucleoside analog antiviral drug approved for the treatment of cytomegalovirus (CMV) retinitis in patients with AIDS. It is currently available only for intravenous infusion. Several small studies and case reports describe the successful use of cidofovir applied either topically or intr...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/s0190-9622(98)70046-5
更新日期:1998-11-01 00:00:00
abstract::A new technic is described for more accurately checking the surgical margins of skin tumors removed by standard surgical excision. Vertical sections of surgical specimens represent check points of the margin only 7 microns thick. This means most of the surgical margin is not checked microscopically, allowing small tum...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(82)70131-8
更新日期:1982-10-01 00:00:00
abstract:BACKGROUND:The potential for wrong-site surgery is a growing concern in dermatology. OBJECTIVE:The purpose of this study was to determine the incidence of difficulty with surgical site identification and possible confounding factors. METHODS:This was a prospective study on 333 Mohs cases performed between April 1, 20...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2012.02.034
更新日期:2012-08-01 00:00:00
abstract:BACKGROUND:Curcuminoids are components of turmeric (Curcuma longa) that possess anti-inflammatory properties. OBJECTIVE:We sought to study the efficacy of curcuminoids in controlling the signs and symptoms of oral lichen planus, at doses of 6000 mg/d (3 divided doses), and their safety at this dose. METHODS:Twenty co...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jaad.2011.04.022
更新日期:2012-05-01 00:00:00
abstract:BACKGROUND:Serum levels of S100A8/A9 may correlate with disease activity in psoriasis. OBJECTIVE:We sought to elucidate the association of serum levels of S100A8/A9 heterodimers with the clinical subtypes of psoriasis and the major cell source. METHODS:Serum samples were collected from patients with psoriasis vulgari...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2010.02.049
更新日期:2011-05-01 00:00:00
abstract::Forty-seven patients with chronic venous leg ulcers were included in a randomized clinical trial to evaluate the efficacy of systemically administered antibiotics in healing with condition. One group was treated by means of elastic support bandages only, whereas the other one received the same local treatment plus sys...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1016/s0190-9622(86)70154-0
更新日期:1986-08-01 00:00:00
abstract:BACKGROUND:Pulsed dye laser treatment and other cosmetic procedures result in significant bruising. Claims have been made regarding the efficacy of topical vitamin K in both preventing and speeding the clearing of bruising; however, well-controlled studies are lacking. OBJECTIVE:The purpose of this study is to evaluat...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1067/mjd.2002.120465
更新日期:2002-08-01 00:00:00
abstract::A 58-year-old man presented with a 4-year history of a slowly enlarging, hyperkeratotic plaque on his glans penis that was compatible with a clinical diagnosis of pseudoepitheliomatous, keratotic, micaceous balanitis. The lesion had been treated unsuccessfully on three occasions with superficial shave excisional biops...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:
更新日期:1988-02-01 00:00:00
abstract::Reflectance confocal microscopy (RCM) is a high-resolution, noninvasive tool that is currently approved by the US Food and Drug Administration for obtaining and interpreting images of the skin and cutaneous neoplasms with the goal of decreasing unnecessary biopsy procedures in patients with benign lesions. The second ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2020.05.154
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Isotretinoin is a very effective drug for treating severe recalcitrant nodular acne. A new micronized formulation of isotretinoin has been shown to be clinically equivalent to standard isotretinoin with improved bioavailability and minimal food effect. The safety profile of the micronized formulation has not...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章,多中心研究,随机对照试验
doi:10.1067/mjd.2001.115966
更新日期:2001-08-01 00:00:00
abstract:BACKGROUND:Evidence on long-term dupilumab treatment for atopic dermatitis in daily practice is lacking. OBJECTIVE:To investigate patient characteristics, treatment aspects, effectiveness, and safety of up to 84 weeks of dupilumab treatment. METHODS:An observational prospective cohort study was conducted of patients ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2020.05.128
更新日期:2020-11-01 00:00:00