Expression of p16 protein in lesional and perilesional condyloma acuminata and bowenoid papulosis: clinical significance and diagnostic implications.

abstract：:Cutaneous metastases present themselves in a variety of clinical patterns and tend to be manifested as indurated papules/nodules/tumors. Some of those clinical expressions are unique for certain types of metastases. This report describes an entirely different phenomenon of clinically incognito cutaneous metastases tha...

journal_title：Journal of the American Academy of Dermatology

authors： Resnik KS,DiLeonardo M,Gibbons G

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Rituximab has been increasingly used in autoimmune blistering dermatoses, mainly in pemphigus. However, only a few larger case series are available on this subject and information on the efficacy of retreatment with rituximab during relapses is lacking. OBJECTIVE:We sought to determine efficacy and adverse ...

journal_title：Journal of the American Academy of Dermatology

authors： Kasperkiewicz M,Shimanovich I,Ludwig RJ,Rose C,Zillikens D,Schmidt E

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:An estimated 750,000 melanoma survivors in the United States are at increased risk of subsequent primary cancers. OBJECTIVE:We sought to assess the risk of developing subsequent primary cancers among people with cutaneous melanoma. METHODS:Using 1992 to 2006 data from the National Cancer Institute Surveill...

journal_title：Journal of the American Academy of Dermatology

authors： Balamurugan A,Rees JR,Kosary C,Rim SH,Li J,Stewart SL

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Nail dystrophies in newborns are rare and are particularly frightening when they appear as masses involving a single digit, suggesting the possibility of a tumor. OBJECTIVE:The aim of this study is to report 3 infants with a congenital pseudoclubbing appearance of a digit and with a reddish discoloration ca...

journal_title：Journal of the American Academy of Dermatology

authors： Piraccini BM,Antonucci A,Rech G,Iorizzo M,Neri I,Patrizi A,Tosti A

更新日期：2005-08-01 00:00:00

abstract：:More than 100,000 species of fungi have been identified worldwide, but only a few dozen are of medical significance. Because of the opportunistic nature of these organisms and the prevalence of immunodeficient conditions, the number of medically important fungi is increasing. Identification of the causative organism i...

journal_title：Journal of the American Academy of Dermatology

authors： Elewski BE,Hazen PG

更新日期：1989-10-01 00:00:00

abstract：BACKGROUND:Facial erythema is a clinical hallmark of rosacea and often causes social and psychological distress. Although facial erythema assessments are a common endpoint in rosacea clinical trials, their reliability has not been evaluated. OBJECTIVE:The objective of this study was to evaluate the inter- and intrarat...

journal_title：Journal of the American Academy of Dermatology

authors： Tan J,Liu H,Leyden JJ,Leoni MJ

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Lymphomatoid papulosis (LyP) is a recurrent hemorrhagic papular skin eruption with a clinically benign course and histopathologic features of lymphoma. OBJECTIVE AND METHODS:To better characterize this disease, we studied 53 patients seen since 1965. RESULTS:A lymphoproliferative malignancy developed withi...

journal_title：Journal of the American Academy of Dermatology

authors： el-Azhary RA,Gibson LE,Kurtin PJ,Pittelkow MR,Muller SA

更新日期：1994-02-01 00:00:00

abstract：:In vivo, topical minoxidil therapy is associated with changes in the follicular epithelium, tissue and blood lymphocyte populations, lymphocyte blastogenic response to mitogens, and perifollicular vasculature. Biopsy specimens taken from areas of terminal hair regrowth show a dose-dependent increase in hair follicle l...

journal_title：Journal of the American Academy of Dermatology

authors： Fiedler-Weiss VC

更新日期：1987-03-01 00:00:00

abstract：:Mycobacterium avium complex, a common opportunistic pathogen among patients with AIDS, usually manifests as disseminated disease involving the lung, lymph nodes, and gastrointestinal tract. Primary cutaneous infections with M avium complex are extremely rare, and most cutaneous lesions are caused by dissemination. Cut...

journal_title：Journal of the American Academy of Dermatology

authors： Kayal JD,McCall CO

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND:The development of autoimmune sequelae is one of the characteristic features of drug reaction with eosinophilia and systemic symptoms (DRESS) or drug-induced hypersensitivity syndrome; however, the incidence of sequelae and prognosis of patients with DRESS are unknown. OBJECTIVE:We sought to investigate the...

journal_title：Journal of the American Academy of Dermatology

authors： Chen YC,Chang CY,Cho YT,Chiu HC,Chu CY

更新日期：2013-03-01 00:00:00

abstract：BACKGROUND:Methyldibromoglutaronitrile (MDGN) is a component of Euxyl K400, a preservative used in many skin care products in Europe. MDGN has been used in skin care products in the United States for the last 5 years. Contact allergy from MDGN has been reported from Europe. OBJECTIVE:The purpose of this study was to d...

journal_title：Journal of the American Academy of Dermatology

authors： Jackson JM,Fowler JF

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Clinical and histopathologic assessment of pigmented skin lesions remains challenging even for experts. Differentiated and accurate noninvasive diagnostic modalities are highly desirable. OBJECTIVE:We sought to provide clinicians with such a tool. METHODS:A 2-gene classification method based on LINC00518 a...

journal_title：Journal of the American Academy of Dermatology

authors： Gerami P,Yao Z,Polsky D,Jansen B,Busam K,Ho J,Martini M,Ferris LK

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Lentigo maligna (LM) is a relatively common tumor with increasing prevalence and substantial morbidity. A variety of treatment modalities are available, though margin-control surgery offers the highest cure rate. We were interested in comparing long-term outcomes of Mohs micrographic surgery (MMS) versus sta...

journal_title：Journal of the American Academy of Dermatology

authors： Walling HW,Scupham RK,Bean AK,Ceilley RI

更新日期：2007-10-01 00:00:00

abstract：BACKGROUND:Clinical and histopathologic features of childhood melanoma are poorly characterized. Atypical clinical presentations and ambiguous microscopic findings may contribute to diagnostic delays. OBJECTIVES:We sought to determine whether conventional ABCDE melanoma detection criteria (Asymmetry, Border irregulari...

journal_title：Journal of the American Academy of Dermatology

authors： Cordoro KM,Gupta D,Frieden IJ,McCalmont T,Kashani-Sabet M

更新日期：2013-06-01 00:00:00

abstract：:A diabetic renal transplant recipient developed fever, generalized rash, and genital ulcers which showed typical histologic changes of cytomegalovirus (CMV) infection in the dermal vascular endothelium. This infection was confirmed by rising serologic titer of specific antibody, positive viral cultures, and typical nu...

journal_title：Journal of the American Academy of Dermatology

authors： Pariser RJ

更新日期：1983-12-01 00:00:00

abstract：:Skin toxicities are the most common side effects associated with the epidermal growth factor receptor inhibitor erlotinib, occurring in most patients receiving the drug. Clinical trials evaluating erlotinib for the treatment of non-small cell lung cancer have reported a range of skin disorders, the most common being a...

journal_title：Journal of the American Academy of Dermatology

authors： Kiyohara Y,Yamazaki N,Kishi A

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Australia's first dedicated photodermatology clinic was established at St Vincent's Hospital Melbourne in 1993. OBJECTIVE:We sought to review clinical diagnoses and results of investigations performed on patients seen at this institution. METHODS:A database was created to enable a retrospective and prospec...

journal_title：Journal of the American Academy of Dermatology

authors： Crouch RB,Foley PA,Baker CS

更新日期：2003-05-01 00:00:00

abstract：:Critical to the proper management of pyoderma gangrenosum are correct diagnosis, identification and treatment of any underlying disorder, and the proper choice of topical and systemic therapy. Many agents are available for the treatment of pyoderma gangrenosum. We review the current therapeutic options, their efficacy...

journal_title：Journal of the American Academy of Dermatology

authors： Chow RK,Ho VC

更新日期：1996-06-01 00:00:00

abstract：BACKGROUND:Preventing fetal exposure to isotretinoin is an important public health goal. Since approval of isotretinoin (1982), the Food and Drug Administration has implemented several unsuccessful risk management programs aimed at preventing fetal exposure. The Kaiser Permanente isotretinoin risk management program in...

journal_title：Journal of the American Academy of Dermatology

authors： Cheetham TC,Wagner RA,Chiu G,Day JM,Yoshinaga MA,Wong L

更新日期：2006-09-01 00:00:00

abstract：:A 65-year-old woman treated with etretinate for pityriasis rubra pilaris developed chronic active hepatitis. The elevated transaminases were noted 2 months after initiation of therapy and peaked 2 months after discontinuation of etretinate. The spectrum of liver toxicity induced by etretinate is reviewed. We suggest t...

journal_title：Journal of the American Academy of Dermatology

authors： Sanchez MR,Ross B,Rotterdam H,Salik J,Brodie R,Freedberg IM

更新日期：1993-05-01 00:00:00

abstract：:Malignant myxoid melanoma (MMM) is a rarely reported variant of malignant melanoma, which can often be confused with other mucin-containing neoplasms. A retrospective study of 3 cases of MMM and a review of the English-language literature was performed. MMM affects an older population and is frequently misdiagnosed. T...

journal_title：Journal of the American Academy of Dermatology

authors： Patel P,Levin K,Waltz K,Helm KF

更新日期：2002-02-01 00:00:00

abstract：:A 65-year-old man with insulin-dependent diabetes developed intractable pruritus preceding weight loss and increasing fatiguability. Esophagogastroduodenoscopy revealed infection with Candida, cytomegalovirus, and Cryptosporidium. His T cell helper/suppressor ratio was inverted, and the serum human immunodeficiency vi...

journal_title：Journal of the American Academy of Dermatology

authors： Shapiro RS,Samorodin C,Hood AF

更新日期：1987-05-01 00:00:00

abstract：:Oral retinoids are among the drugs of choice for pustular and erythrodermic psoriasis. In addition, retinoids are effective in combination with other topical and systemic agents for the treatment of plaque-type psoriasis. Acitretin, the active retinoid metabolite, has replaced etretinate in retinoid therapy of psorias...

journal_title：Journal of the American Academy of Dermatology

authors： Katz HI,Waalen J,Leach EE

更新日期：1999-09-01 00:00:00

abstract：:Although sclerotherapy is an established procedure to treat ectatic veins, a wide disparity remains in the reported rates of success, especially for larger varicose veins. This article reviews the venous anatomy of the lower extremity and outlines the indications for sclerotherapy. The historical basis for treatment t...

journal_title：Journal of the American Academy of Dermatology

authors： Green D

更新日期：1998-03-01 00:00:00

abstract：:The case of a 2-year-old Puerto Rican boy is presented. Clinical and histologic features are detailed because he showed peculiar jet black patches of pigmentation on the fingers of the right hand. This case, except for the lack of progression of the disease after a 2-year period of follow-up, shows many similarities t...

journal_title：Journal of the American Academy of Dermatology

authors： González JR,Vázquez Botet M

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND:Although rare in the general population, highly penetrant germline mutations in CDKN2A are responsible for 5%-40% of melanoma cases reported in melanoma-prone families. We sought to determine whether MELPREDICT was generalizable to a global series of families with melanoma and whether performance improvement...

journal_title：Journal of the American Academy of Dermatology

authors： Taylor NJ,Mitra N,Qian L,Avril MF,Bishop DT,Bressac-de Paillerets B,Bruno W,Calista D,Cuellar F,Cust AE,Demenais F,Elder DE,Gerdes AM,Ghiorzo P,Goldstein AM,Grazziotin TC,Gruis NA,Hansson J,Harland M,Hayward NK,Ho

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Despite improvements in melanoma mortality, disparities in melanoma survival persist. We evaluated possible sociodemographic and health care-based predictors of differences in melanoma survival in the United States by using the melanoma mortality-to-incidence ratio (MIR). METHODS:State-based MIRs were calcu...

journal_title：Journal of the American Academy of Dermatology

authors： Hopkins ZH,Moreno C,Carlisle R,Secrest AM

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Noninvasive fat removal is preferred because of decreased downtime and lower perceived risk. It is important to seek new noninvasive fat removal treatments that are both safe and efficacious. OBJECTIVE:To assess the extent to which carboxytherapy, which is the insufflation of carbon dioxide gas into subcuta...

journal_title：Journal of the American Academy of Dermatology

authors： Alam M,Sadhwani D,Geisler A,Aslam I,Makin IRS,Schlessinger DI,Disphanurat W,Pongprutthipan M,Voravutinon N,Weil A,Chen BR,West DP,Veledar E,Poon E

更新日期：2018-08-01 00:00:00

abstract：BACKGROUND:We have used a schedule for soft x-ray therapy of epithelial malignancies that takes into account the clinically diagnosed tumor involution under treatment. OBJECTIVE:We sought to evaluate the effectiveness of this schedule in terms of cure rate and late ulcerations. METHODS:Patients with 1267 consecutivel...

journal_title：Journal of the American Academy of Dermatology

authors： Schulte KW,Lippold A,Auras C,Bramkamp G,Breitkopf C,Elsmann HJ,Habenicht EM,Jasnoch V,Müller-Pannes H,Rupprecht R,Suter L

更新日期：2005-12-01 00:00:00

abstract：BACKGROUND:Nephrogenic systemic fibrosis is a fibrosing disorder associated with gadolinium (Gd)-based contrast agents dosed during renal insufficiency. OBJECTIVE:In two patients, Gd deposition in tissue affected by nephrogenic systemic fibrosis was quantified using inductively coupled plasma mass spectrometry. The pr...

journal_title：Journal of the American Academy of Dermatology

authors： High WA,Ranville JF,Brown M,Punshon T,Lanzirotti A,Jackson BP

更新日期：2010-01-01 00:00:00