The superficial mycoses and the dermatophytes.

abstract：:To determine whether systemic hydrocortisone can elicit allergic skin reactions in patients with contact hypersensitivity to hydrocortisone, we studied four patients with contact hypersensitivity to hydrocortisone and hydrocortisone-17-butyrate and two patients with contact hypersensitivity to hydrocortisone-17-butyra...

journal_title：Journal of the American Academy of Dermatology

authors： Lauerma AI,Reitamo S,Maibach HI

更新日期：1991-02-01 00:00:00

abstract：:Most cutaneous squamous cell carcinomas (SCCs) of the trunk and extremities are small enough to be cured by simple surgical excision. Because the risk of metastasis of SCCs of the head and neck arising from mucosal surfaces is higher than the risk of metastasis of SCCs arising from cutaneous surfaces, it may be more a...

journal_title：Journal of the American Academy of Dermatology

authors： Geohas J,Roholt NS,Robinson JK

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:Clusters of rare cylindroma or spiradenoma tumors are a recurrent clinical presentation, yet conventional genetic testing results in individuals with these tumors are frequently normal. OBJECTIVE:To determine if genetic mosaicism accounts for such cases. METHODS:A study of 6 cases from a series of 55 patie...

journal_title：Journal of the American Academy of Dermatology

authors： Arefi M,Wilson V,Muthiah S,Zwolinski S,Bajwa D,Brennan P,Blasdale K,Bourn D,Burn J,Santibanez-Koref M,Rajan N

更新日期：2019-12-01 00:00:00

abstract：:It has long been observed that sun exposure can induce or exacerbate skin lesions in patients with certain forms of lupus erythematosus. Despite the frequency of photosensitivity in these patients, the mechanism by which ultraviolet radiation alters the pathogenic course of this disease remains poorly understood. Afte...

journal_title：Journal of the American Academy of Dermatology

authors： Kuhn A,Sonntag M,Richter-Hintz D,Oslislo C,Megahed M,Ruzicka T,Lehmann P

更新日期：2001-07-01 00:00:00

abstract：:Photodamaged skin occurs as a result of long-term exposure to ultraviolet radiation. The incidence of photodamage in European and North American populations with Fitzpatrick skin types I, II, and III is estimated at 80% to 90%. We conducted a double-blind clinical trial to test the efficacy and safety of 0.1% isotreti...

journal_title：Journal of the American Academy of Dermatology

authors： Maddin S,Lauharanta J,Agache P,Burrows L,Zultak M,Bulger L

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND:Clinical and histopathologic assessment of pigmented skin lesions remains challenging even for experts. Differentiated and accurate noninvasive diagnostic modalities are highly desirable. OBJECTIVE:We sought to provide clinicians with such a tool. METHODS:A 2-gene classification method based on LINC00518 a...

journal_title：Journal of the American Academy of Dermatology

authors： Gerami P,Yao Z,Polsky D,Jansen B,Busam K,Ho J,Martini M,Ferris LK

更新日期：2017-01-01 00:00:00

abstract：:Global temperatures continue to rise, reaching new records almost every year this decade. Although the causes are debated, climate change is a reality. Consequences of climate change include melting of the arctic ice cap, rising of sea levels, changes in precipitation patterns, and increased severe weather events. Thi...

journal_title：Journal of the American Academy of Dermatology

authors： Kaffenberger BH,Shetlar D,Norton SA,Rosenbach M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Only a few reports have been published on the long-term outcome of surgical excision of cutaneous squamous cell carcinoma (SCC). OBJECTIVE:Our purpose was to report the clinical findings and 5-year recurrence rate of all patients with cutaneous SCC treated with Mohs micrographic surgery (MMS) in Australia b...

journal_title：Journal of the American Academy of Dermatology

authors： Leibovitch I,Huilgol SC,Selva D,Hill D,Richards S,Paver R

更新日期：2005-08-01 00:00:00

abstract：:We used an avidin-biotin complex immunoperoxidase technique with various monoclonal antibodies to determine Langerhans cell densities, class II antigen expression on keratinocytes, and phenotypes of other infiltrating cells in several malignant and benign epithelial tumors of the skin. Our observations indicate (1) th...

journal_title：Journal of the American Academy of Dermatology

authors： Chen HD,Zhao YM,Sun G,Yang CY

更新日期：1989-06-01 00:00:00

abstract：:The clinical and histologic spectrum of melanotic macule of the nail unit is examined and the differences in the clinical appearance of longitudinal melanochychia caused by melanotic macule and by other kinds of proliferations of melanocytes are assessed. We observed that the clinical appearance of the pigmented band ...

journal_title：Journal of the American Academy of Dermatology

authors： Husain S,Scher RK,Silvers DN,Ackerman AB

更新日期：2006-04-01 00:00:00

abstract：:It is well established that ultraviolet (UV) radiation from sunlight damages skin cells' DNA. Wavelengths in the UVB range are absorbed by DNA and can induce mutagenic lesions such as pyrimidine dimers. On the other hand, genotoxic effects of solar UVA are mainly mediated by the activation of endogenous photosensitize...

journal_title：Journal of the American Academy of Dermatology

authors： Marrot L,Meunier JR

更新日期：2008-05-01 00:00:00

abstract：:A patient is described who developed sore throat, palpable purpura, and a distinctive panniculitis. The pathologic alterations in the subcutis were similar to what Wells described in the dermis as eosinophilic cellulitis. In our experience the presence of such a picture primarily in the subcutis is unique. Streptococc...

journal_title：Journal of the American Academy of Dermatology

authors： Burket JM,Burket BJ

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:Since publication in 2000 of the Second International Consensus Report on Diagnosis and Classification of Epidermolysis Bullosa, many advances have been made to our understanding of this group of diseases, both clinically and molecularly. At the same time, new epidermolysis bullosa (EB) subtypes have been de...

journal_title：Journal of the American Academy of Dermatology

authors： Fine JD,Eady RA,Bauer EA,Bauer JW,Bruckner-Tuderman L,Heagerty A,Hintner H,Hovnanian A,Jonkman MF,Leigh I,McGrath JA,Mellerio JE,Murrell DF,Shimizu H,Uitto J,Vahlquist A,Woodley D,Zambruno G

更新日期：2008-06-01 00:00:00

abstract：:Benign lymphangiomatous papules of the skin are benign lymphatic proliferations that may arise in the skin after operation or radiation therapy. We report a case of benign lymphangiomatous papules of the skin that occurred in a patient 4 years after undergoing radiation therapy to the chest for adenocarcinoma of the b...

journal_title：Journal of the American Academy of Dermatology

authors： Wagamon K,Ranchoff RE,Rosenberg AS,Jaworsky C

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Hydroxychloroquine is widely used for the treatment of cutaneous lupus erythematosus (CLE). Although new recommendations exist for hydroxychloroquine dosing, there is still uncertainty about the dosage that will elicit a satisfactory response in CLE while limiting adverse effects, specifically retinopathy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Shipman WD,Vernice NA,Demetres M,Jorizzo JL

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Patients with pemphigus vulgaris (PV) are genetically linked to two alleles of the HLA subgroup, and circulating antibodies were found in first-degree relatives of these patients, thus showing genetic predisposition. OBJECTIVE:Our purpose was to determine the occurrence of circulating true PV-IgG in patient...

journal_title：Journal of the American Academy of Dermatology

authors： Brandsen R,Frusic-Zlotkin M,Lyubimov H,Yunes F,Michel B,Tamir A,Milner Y,Brenner S

更新日期：1997-01-01 00:00:00

abstract：BACKGROUND:Onychomatricoma (OM) is a rare benign tumor of the nail matrix in which genome-wide analyses have never been performed. It is clinically characterized by an increased transversal curvature of the nail plate, a longitudinal yellowish discoloration, and splinter hemorrhages. Once the nail plate has been remove...

journal_title：Journal of the American Academy of Dermatology

authors： Cañueto J,Santos-Briz Á,García JL,Robledo C,Unamuno P

更新日期：2011-03-01 00:00:00

abstract：:A panel of antibodies reactive in routinely fixed, paraffin-embedded tissue sections was compared with a panel of antibodies reactive in frozen sections for the immunophenotyping of cutaneous lymphoproliferative disorders. Three T cell-associated markers (UCHL1, MT-1, MT-2, six B cell-associated markers (MB-1, MB-2, L...

journal_title：Journal of the American Academy of Dermatology

authors： Cerroni L,Smolle J,Soyer HP,Martinez Aparicio A,Kerl H

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:Hereditary palmoplantar keratoderma (HPPK), type papulosa, is rare, and epidemiologic data are sporadic and inconsistent. An epidemiologic population study of this disease has not been performed previously. OBJECTIVE:We performed a large population study on prevalence of HPPK, type papulosa, in Croatia. ME...

journal_title：Journal of the American Academy of Dermatology

authors： Stanimirović A,Kansky A,Basta-Juzbasić A,Skerlev M,Beck T

更新日期：1993-09-01 00:00:00

abstract：:A new disorder of the hair follicle is described that leads to increased fragility of the shaft. Light microscopic studies of hair follicles revealed disturbances of keratinization in the shafts that are very likely responsible for the breakage. The most consistent change seen by transmission electron microscopy was i...

journal_title：Journal of the American Academy of Dermatology

authors： Birnbaum PS,Baden HP,Bronstein BR,Nakagawa H,Hori Y

更新日期：1986-07-01 00:00:00

abstract：BACKGROUND:Some patients with pemphigus vulgaris (PV) have mucous membrane erosions with minimal skin involvement (mucosal dominant type), and others show extensive skin blisters and erosions in addition to mucous membrane involvement (mucocutaneous type). Patients with pemphigus foliaceus (PF) show only skin involveme...

journal_title：Journal of the American Academy of Dermatology

authors： Amagai M,Tsunoda K,Zillikens D,Nagai T,Nishikawa T

更新日期：1999-02-01 00:00:00

abstract：:We report a case of a patient with scleromyxedema limited to the skin with an associated IgG lambda monoclonal protein treated successfully with high-dose dexamethasone. We encourage the continued investigation of this complex relationship between the clinical presentation of scleromyxedema and its frequently associat...

journal_title：Journal of the American Academy of Dermatology

authors： Horn KB,Horn MA,Swan J,Singhal S,Guitart J

更新日期：2004-08-01 00:00:00

abstract：:Cicatricial pemphigoid is a chronic, presumed autoimmune, blistering disease of the mucous membranes and occasionally of the skin. The characteristic feature is scarring at the sites of healing. We report the use of thalidomide as a therapeutic agent to control previously resistant disease. ...

journal_title：Journal of the American Academy of Dermatology

authors： Duong DJ,Moxley RT 3rd,Kellman RM,Pincus SH,Gaspari AA

更新日期：2002-08-01 00:00:00

abstract：BACKGROUND:Paraneoplastic syndromes (PNS) are commonly associated with neuroendocrine cancers, such as small cell lung cancer. OBJECTIVES:We examined the association of PNS in Merkel cell carcinoma (MCC), a rare neuroendocrine skin cancer. METHODS:We identified PNS associated with MCC based on chart review of a Seatt...

journal_title：Journal of the American Academy of Dermatology

authors： Iyer JG,Parvathaneni K,Bhatia S,Tarabadkar ES,Blom A,Doumani R,McKenzie J,Asgari MM,Nghiem P

更新日期：2016-09-01 00:00:00

abstract：:Atopic dermatitis is a chronic inflammatory skin disease that is frequently associated with respiratory allergies. Atopic dermatitis develops as a result of a complex interrelationship of environmental, immunologic, genetic, and pharmacologic factors. Efforts to understand the relative contributions of these factors h...

journal_title：Journal of the American Academy of Dermatology

authors： Leung DY,Soter NA

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Onychomycosis is a prevalent infection of the nail caused primarily by dermatophytes. Fluconazole is active in vitro against the most common pathogens, penetrates into the nail bed, and is clinically effective in the treatment of a wide variety of fungal infections. OBJECTIVE:The purpose of this study was t...

journal_title：Journal of the American Academy of Dermatology

authors： Drake L,Babel D,Stewart DM,Rich P,Ling MR,Breneman D,Scher RK,Martin AG,Pariser DM,Pariser RJ,Ellis CN,Kang S,Katz HI,McDonald CJ,Muglia J,Savin RC,Webster G,Elewski BE,Leyden JJ,Bucko AD,Tschen EH,Hanifin JM,

更新日期：1998-06-01 00:00:00

abstract：BACKGROUND:Acne is one of the most common concerns of patients with body dysmorphic disorder (BDD), a psychiatric condition defined as a preoccupation with a slight or imagined defect in appearance that causes significant disruption in daily functioning. OBJECTIVE:We sought to screen for BDD symptoms among patients wi...

journal_title：Journal of the American Academy of Dermatology

authors： Bowe WP,Leyden JJ,Crerand CE,Sarwer DB,Margolis DJ

更新日期：2007-08-01 00:00:00

abstract：:A 72-year-old woman with a large mass on her forehead was found to have primary cutaneous CD30-positive large T-cell lymphoma and was treated with radiation therapy. Five weeks after the completion of radiation therapy, a large, yellow plaque developed on the forehead. Histopathologic examination showed numerous xanth...

journal_title：Journal of the American Academy of Dermatology

authors： Chung HG,Chung YL,Kang JM,Yang WI,Suh CO,Hahn JS,Leea MG

更新日期：2003-02-01 00:00:00

abstract：:A 58-year-old man presented with a 4-year history of a slowly enlarging, hyperkeratotic plaque on his glans penis that was compatible with a clinical diagnosis of pseudoepitheliomatous, keratotic, micaceous balanitis. The lesion had been treated unsuccessfully on three occasions with superficial shave excisional biops...

journal_title：Journal of the American Academy of Dermatology

authors： Jenkins D Jr,Jakubovic HR

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Inability of topical medications to penetrate via nail plate brings a great challenge to clinicians in treating onychomycosis. Furthermore, oral medications are not appropriate for all patients because of drug interactions, adverse effects, and contraindications. OBJECTIVE:We sought to evaluate the clinical...

journal_title：Journal of the American Academy of Dermatology

authors： Bhatta AK,Keyal U,Huang X,Zhao JJ

更新日期：2016-05-01 00:00:00