Tuberculous ulcer of the skin.

abstract：:The efficacy of a sunscreen containing an investigational drug, butyl methoxydibenzoylmethane in combination with padimate O against the erythemogenic effect of ultraviolet A (UVA) radiation was evaluated in two double-blind studies involving subjects sensitized with topical 8-methoxypsoralen. UVA radiation was suppli...

journal_title：Journal of the American Academy of Dermatology

authors： Lowe NJ,Dromgoole SH,Sefton J,Bourget T,Weingarten D

更新日期：1987-08-01 00:00:00

abstract：:We report a case of a 10-month-old male infant with GM1 type 1 gangliosidosis who also had hyperpigmented macules and patches. Light and electron microscopic findings correlated with previously published reports on findings in skin biopsy specimens of patients with lipid storage disorders. The hyperpigmented macules a...

journal_title：Journal of the American Academy of Dermatology

authors： Selsor LC,Lesher JL Jr

更新日期：1989-05-01 00:00:00

abstract：:"Poikiloderma" is a morphologic and descriptive term referring to a combination of cutaneous atrophy, telangiectasia, and varied macular pigmentary changes that result in a mottled skin appearance. Its etiology includes both congenital and acquired causes. Many studies have reported different causes of acquired poikil...

journal_title：Journal of the American Academy of Dermatology

authors： Nofal A,Salah E

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:It is unclear whether the type 2 T helper cell-specific immunosuppressive action of dupilumab interferes with patch testing. OBJECTIVES:We sought to evaluate the reliability of patch testing on dupilumab and the contribution of allergic contact dermatitis (ACD) to complex dermatitis in patients with residua...

journal_title：Journal of the American Academy of Dermatology

authors： Raffi J,Suresh R,Botto N,Murase JE

更新日期：2020-01-01 00:00:00

abstract：:Blue-brown macules of the face occurring on both sides of the forehead, temple, eyelids, malar area, alae of the nose, and root of the nose are often observed in middle-aged Japanese women. These lesions histologically are a form of dermal melanocytosis as shown by electron microscopic examination. They differ clinica...

journal_title：Journal of the American Academy of Dermatology

authors： Hori Y,Kawashima M,Oohara K,Kukita A

更新日期：1984-06-01 00:00:00

abstract：:Scleromyxedema is a rare cutaneous disease with occasional systemic involvement and characteristic poor response to treatment. A case of scleromyxedema associated with renal scleroderma and acute psychosis is presented, along with a review of treatment and associated internal disorders. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kantor GR,Bergfeld WF,Katzin WE,Reynolds OD,Biscardi AP,Lobur DM,Box TA,Schreiber MJ Jr,Ratliff NB

更新日期：1986-05-01 00:00:00

abstract：CAPSULE SUMMARY:In this article, we try to use the syringes without the piston part to control the amount of saline fluid in dermabrasion surgery. It is very convenient to obtain materials and simple to operate in skin surgery. ...

journal_title：Journal of the American Academy of Dermatology

authors： Cao C,Li H,Shao Z

更新日期：2020-10-10 00:00:00

abstract：:We present further evidence that granuloma annulare and autoimmune thyroiditis may be associated. Only 11 cases have been previously reported with this association as far as we know. It may be advantageous to consider checking the thyroid-stimulating hormone and/or antithyroid antibodies before administering medicatio...

journal_title：Journal of the American Academy of Dermatology

authors： Vázquez-López F,González-López MA,Raya-Aguado C,Pérez-Oliva N

更新日期：2000-11-01 00:00:00

abstract：:Global temperatures continue to rise, reaching new records almost every year this decade. Although the causes are debated, climate change is a reality. Consequences of climate change include melting of the arctic ice cap, rising of sea levels, changes in precipitation patterns, and increased severe weather events. Thi...

journal_title：Journal of the American Academy of Dermatology

authors： Kaffenberger BH,Shetlar D,Norton SA,Rosenbach M

更新日期：2017-01-01 00:00:00

abstract：:Molecular and cellular understanding of psoriasis pathogenesis has evolved considerably over the last 30 years beginning in the early 1980s when psoriasis was thought to be a skin disease driven by keratinocyte hyperproliferation. During the next 20 years, the role of the immune system and T-helper (Th) cells in psori...

journal_title：Journal of the American Academy of Dermatology

authors： Lynde CW,Poulin Y,Vender R,Bourcier M,Khalil S

更新日期：2014-07-01 00:00:00

abstract：:A 49-year-old man presented with an acute onset of folliculitis on his right cheek. The folliculitis was unresponsive to antibiotics. A potassium hydroxide preparation of a scraping from the affected area revealed the presence of numerous Demodex mites. The patient was treated with topical crotamiton (Eurax) cream res...

journal_title：Journal of the American Academy of Dermatology

authors： Purcell SM,Hayes TJ,Dixon SL

更新日期：1986-11-01 00:00:00

abstract：BACKGROUND:The efficacy of combination therapy with topical corticosteroids and tacrolimus in the treatment of atopic dermatitis remains to be established. OBJECTIVE:Our aim was to determine whether a regimen of sequential application of topical corticosteroids and topical tacrolimus is effective in the treatment of p...

journal_title：Journal of the American Academy of Dermatology

authors： Kubota Y,Yoneda K,Nakai K,Katsuura J,Moriue T,Matsuoka Y,Miyamoto I,Ohya Y

更新日期：2009-02-01 00:00:00

abstract：:Phototherapy is a mainstay in the treatment of psoriasis and is available as psoralen plus UVA (PUVA), broadband UVB (BB-UVB), and narrowband UVB (NB-UVB). Phototherapy can be administered in the hospital, outpatient clinic, or in the patient's home. The purpose of this review is to provide some practical guidance to ...

journal_title：Journal of the American Academy of Dermatology

authors： Lapolla W,Yentzer BA,Bagel J,Halvorson CR,Feldman SR

更新日期：2011-05-01 00:00:00

abstract：:Twelve skin biopsy specimens of lymphomatoid papulosis from nine patients were studied immunohistologically. The large atypical cells morphologically resembled Reed-Sternberg cells in six cases and large cerebriform mononuclear cells in three cases. These cells expressed pan-T cell antigens (Leu-4 and/or Leu-5) and he...

journal_title：Journal of the American Academy of Dermatology

authors： Wood GS,Strickler JG,Deneau DG,Egbert B,Warnke RA

更新日期：1986-09-01 00:00:00

abstract：UNLABELLED:Cyclosporine is highly effective in the treatment of a multitude of dermatoses. Concern over its side effect profile has limited its use in dermatology. Adverse effects are, for the most part, dose dependent and related to duration of therapy. Using the recommended monitoring protocols results in a significa...

journal_title：Journal of the American Academy of Dermatology

authors： Ryan C,Amor KT,Menter A

更新日期：2010-12-01 00:00:00

abstract：:Nevoid hyperkeratosis of the nipple and areola, which is characterized by verrucous thickening and pigmentation of the nipple or areola, is a rare condition. Different therapeutic options have been used with varying results, but there is no uniformly effective treatment. We describe two patients with hyperkeratosis of...

journal_title：Journal of the American Academy of Dermatology

authors： Bayramgürler D,Bilen N,Apaydin R,Erçin C

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:In the United States, complementary and alternative medicine (CAM) is used for a variety of diseases, including those of the skin. An estimate of the prevalence of CAM use among adults with skin disease using the alternative health supplement of the 2002 National Health Interview Survey (NHIS) has been publi...

journal_title：Journal of the American Academy of Dermatology

authors： Fuhrmann T,Smith N,Tausk F

更新日期：2010-12-01 00:00:00

abstract：:A woman with pemphigus vulgaris was treated by plasma exchange. Four separate exchanges of approximately 4,000 ml each were performed over a 2-week period. The patient's pemphigus antibody titer decreased from 1/320 before the first exchange to 1/20 after the final exchange, and no new lesions developed for 3 weeks fo...

journal_title：Journal of the American Academy of Dermatology

authors： Swanson DL,Dahl MV

更新日期：1981-03-01 00:00:00

abstract：:The treatment of hidradenitis suppurativa (HS) has remained challenging because of the many knowledge gaps regarding etiology. However, recent studies into the pathogenesis of HS have enabled the investigation of newer therapies. The second article in this continuing medical education series reviews the evidence for e...

journal_title：Journal of the American Academy of Dermatology

authors： Goldburg SR,Strober BE,Payette MJ

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:For treatment of localized scleroderma numerous treatments, including ones with potentially hazardous side effects, are currently used with only limited success. OBJECTIVE:We attempted to determine the efficacy of low-dose UVA1 irradiation in patients with severe localized scleroderma. METHODS:Patients wer...

journal_title：Journal of the American Academy of Dermatology

authors： Kerscher M,Volkenandt M,Gruss C,Reuther T,von Kobyletzki G,Freitag M,Dirschka T,Altmeyer P

更新日期：1998-01-01 00:00:00

abstract：BACKGROUND:The association of nonparaneoplastic pemphigus with comorbid hematologic malignancies has yet to be established. OBJECTIVE:To estimate the association between pemphigus and the common types of hematologic malignancies. METHODS:A cross-sectional study was conducted comparing pemphigus patients with age-, se...

journal_title：Journal of the American Academy of Dermatology

authors： Kridin K,Zelber-Sagi S,Comaneshter D,Batat E,Cohen AD

更新日期：2018-06-01 00:00:00

abstract：BACKGROUND:Among the papular-pruriginous dermatoses related to human immunodeficiency (HIV) infection, two entities remain poorly differentiated leading to confusion in their diagnosis: HIV-related pruritic papular eruption (HIV-PPE or prurigo) and eosinophilic folliculitis (HIV-EF). OBJECTIVE:To establish histopathol...

journal_title：Journal of the American Academy of Dermatology

authors： Afonso JP,Tomimori J,Michalany NS,Nonogaki S,Porro AM

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Phototherapy may be effective in atopic dermatitis (AD). Medium-dose (MD) ultraviolet (UV) A1 was introduced for the treatment of AD. Few immunohistochemical data are available pertaining to phototherapy in AD. Regulatory T cells may play a role in clearing AD. OBJECTIVES:We sought to compare the clinical a...

journal_title：Journal of the American Academy of Dermatology

authors： Majoie IM,Oldhoff JM,van Weelden H,Laaper-Ertmann M,Bousema MT,Sigurdsson V,Knol EF,Bruijnzeel-Koomen CA,de Bruin-Weller MS

更新日期：2009-01-01 00:00:00

abstract：BACKGROUND:Lymphomatoid papulosis (LyP) is a recurrent hemorrhagic papular skin eruption with a clinically benign course and histopathologic features of lymphoma. OBJECTIVE AND METHODS:To better characterize this disease, we studied 53 patients seen since 1965. RESULTS:A lymphoproliferative malignancy developed withi...

journal_title：Journal of the American Academy of Dermatology

authors： el-Azhary RA,Gibson LE,Kurtin PJ,Pittelkow MR,Muller SA

更新日期：1994-02-01 00:00:00

abstract：BACKGROUND:The antioxidants selenium and vitamin E can be effective in reducing acute and chronic ultraviolet (UV)-induced skin damage. OBJECTIVE:This study investigated whether topical L-selenomethionine with topical RRR-alpha-tocopherol (Eol) or oral RRR-alpha-tocopheryl acetate (Eac) can reduce the incidence of UV-...

journal_title：Journal of the American Academy of Dermatology

authors： Burke KE,Clive J,Combs GF Jr,Nakamura RM

更新日期：2003-09-01 00:00:00

abstract：BACKGROUND:Nail dystrophies in newborns are rare and are particularly frightening when they appear as masses involving a single digit, suggesting the possibility of a tumor. OBJECTIVE:The aim of this study is to report 3 infants with a congenital pseudoclubbing appearance of a digit and with a reddish discoloration ca...

journal_title：Journal of the American Academy of Dermatology

authors： Piraccini BM,Antonucci A,Rech G,Iorizzo M,Neri I,Patrizi A,Tosti A

更新日期：2005-08-01 00:00:00

abstract：:A case of malignant bronchial carcinoid with multiple cutaneous metastases is reported. Despite the extremely aggressive behavior of the disease and the presence of multiple hepatic metastases, the patient did not exhibit the usual clinical features of the carcinoid syndrome. The relevance of the finding of elevated 2...

journal_title：Journal of the American Academy of Dermatology

authors： Archer CB,Wells RS,MacDonald DM

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Drug-specific T cells are involved in the pathogenesis of cutaneous adverse drug reactions (CADRs). OBJECTIVE:We sought to evaluate the diagnostic role of in vitro drug-induced release of interferon gamma in CADRs. METHODS:The study group consisted of 36 patients with CADRs after intake of 106 drugs that w...

journal_title：Journal of the American Academy of Dermatology

authors： Halevy S,Cohen AD,Grossman N

更新日期：2005-02-01 00:00:00

abstract：:The tumor-promoting phorbol ester, 12-O-tetradecanoylphorbol-13-acetate (TPA) causes a dose-dependent induction (up to 300-fold) of ornithine decarboxylase activity in the epidermis of intact mice within 5 hours after the application to the skin of from 1 to 10 nmoles of the ester in 0.2 ml of acetone. Enzyme activity...

journal_title：Journal of the American Academy of Dermatology

authors： Boutwell RK

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:Vascular cell adhesion molecule-1 (VCAM-1) is an endothelial protein with adhesive properties for inflammatory cells including lymphocytes. Its role in skin disease and regulation in vivo are uncertain. OBJECTIVE:Our purpose was to determine expression of VCAM-1 in normal and inflamed skin and the effect on...

journal_title：Journal of the American Academy of Dermatology

authors： Groves RW,Ross EL,Barker JN,MacDonald DM

更新日期：1993-07-01 00:00:00