Topical nitrogen mustard in the treatment of alopecia areata: a bilateral comparison study.

abstract：UNLABELLED:Mycophenolate mofetil (MMF) is the prodrug of mycophenolic acid (MPA), a medication used to treat psoriasis in the 1970s until side effects and the concern of carcinogenesis led to its discontinuation. The prodrug, MMF, emerged decades later in the transplant field. Dermatologists have since used MMF off-lab...

journal_title：Journal of the American Academy of Dermatology

authors： Orvis AK,Wesson SK,Breza TS Jr,Church AA,Mitchell CL,Watkins SW

更新日期：2009-02-01 00:00:00

abstract：:Photodynamic therapy (PDT) is a treatment based on the accumulation of a photosensitizer in the target cells and their selective destruction by irradiation with visible light. In the past 10 years, several patients with cutaneous T cell lymphoma have been successfully treated. The use of PDT in cutaneous B cell lympho...

journal_title：Journal of the American Academy of Dermatology

authors： Mori M,Campolmi P,Mavilia L,Rossi R,Cappugi P,Pimpinelli N

更新日期：2006-03-01 00:00:00

abstract：:Erythema multiforme and Stevens-Johnson syndrome are both characterized by areas of epithelial necrosis. An important clinical feature that distinguishes the two is the extensive mucosal necrosis in Stevens-Johnson syndrome but not in erythema multiforme. Because significant and serious complications may develop with ...

journal_title：Journal of the American Academy of Dermatology

authors： Weston WL,Morelli JG,Rogers M

更新日期：1997-11-01 00:00:00

abstract：:The Cosmetic Ingredient Review (CIR) program was established in 1976 by the Cosmetics, Toiletry, and Fragrance Association, with the support of the Food and Drug Administration (FDA) and the Consumer Federation of America (CFA). CIR performs independent, expert reviews to determine if ingredients used in cosmetics are...

journal_title：Journal of the American Academy of Dermatology

authors： Bergfeld WF,Belsito DV,Marks JG Jr,Andersen FA

更新日期：2005-01-01 00:00:00

abstract：:Verruciform xanthomas occur on mucocutaneous surfaces and are characterized by hyperkeratosis, acanthosis, and the occurrence of "foam cells" stuffed with lipid surrounding capillaries in the dermis between rete pegs. Ultrastructural examination of a lesion on the penis revealed the presence of melanocytes with many l...

journal_title：Journal of the American Academy of Dermatology

authors： Balus S,Breathnach AS,O'Grady AJ

更新日期：1991-05-01 00:00:00

abstract：:Retiform hemangioendothelioma is a rare low-grade angiosarcoma of the skin. It shares some clinical characteristics with Kaposi's sarcoma, a tumor with known human herpesvirus 8 (HHV-8) association. We report a case of retiform hemangioendothelioma in which we detected HHV-8 DNA sequences. ...

journal_title：Journal of the American Academy of Dermatology

authors： Schommer M,Herbst RA,Brodersen JP,Kiehl P,Katenkamp D,Kapp A,Weiss J

更新日期：2000-02-01 00:00:00

abstract：BACKGROUND:Inherited susceptibility genes have been associated with histopathologic characteristics of tumors. OBJECTIVE:We sought to identify associations between histology of melanomas and CDKN2A genotype. METHODS:This was a case-control study design comparing 28 histopathologic tumor features among individuals wit...

journal_title：Journal of the American Academy of Dermatology

authors： Sargen MR,Kanetsky PA,Newton-Bishop J,Hayward NK,Mann GJ,Gruis NA,Tucker MA,Goldstein AM,Bianchi-Scarra G,Puig S,Elder DE

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Degos disease or malignant atrophic papulosis is a rare occlusive vasculopathic disease characterized by pathognomonic cutaneous lesions and frequently fatal systemic involvement. The etiology of malignant atrophic papulosis remains unclear, and there is currently no effective treatment for malignant atrophi...

journal_title：Journal of the American Academy of Dermatology

authors： Meephansan J,Komine M,Hosoda S,Tsuda H,Karakawa M,Murata S,Demitsu T,Ohtsuki M

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Excess cathelicidin and kallikrein 5 (KLK5) have been hypothesized to play a role in the pathophysiology of rosacea. OBJECTIVE:We sought to evaluate the effects of azelaic acid (AzA) on these elements of the innate immune system. METHODS:Gene expression and protease activity were measured in laboratory mod...

journal_title：Journal of the American Academy of Dermatology

authors： Coda AB,Hata T,Miller J,Audish D,Kotol P,Two A,Shafiq F,Yamasaki K,Harper JC,Del Rosso JQ,Gallo RL

更新日期：2013-10-01 00:00:00

abstract：:Reflex sympathetic dystrophy (RSD) is a poorly understood neurovascular disorder characterized by pain, altered sensation, motor disturbance, soft tissue changes, vasomotor changes, and autonomic changes that occurs after trauma to an extremity. Unilateral leukonychia, Beau's lines, nailfold swelling, and nail clubbin...

journal_title：Journal of the American Academy of Dermatology

authors： Pucevich B,Spencer L,English JC 3rd

更新日期：2008-02-01 00:00:00

abstract：BACKGROUND:Lipodermatosclerosis is a sequela of deep venous insufficiency and a risk factor for the occurrence of venous leg ulceration. Medical compression stockings facilitate leg ulcer healing and prevent occurrence of ulcers resulting from removal of edema. Although the exact level of compression necessary for remo...

journal_title：Journal of the American Academy of Dermatology

authors： Gniadecka M,Karlsmark T,Bertram A

更新日期：1998-12-01 00:00:00

abstract：BACKGROUND:Non-adherence rates are high among patients with psoriasis, partly because of discordance between recommended treatments and individual preferences. OBJECTIVES:Our aim was to assess the impact of comorbidities on patients' preferences for psoriasis treatments. METHODS:A computer-based conjoint analysis exp...

journal_title：Journal of the American Academy of Dermatology

authors： Schmieder A,Schaarschmidt ML,Umar N,Terris DD,Goebeler M,Goerdt S,Peitsch WK

更新日期：2012-09-01 00:00:00

abstract：:It is well established that ultraviolet (UV) radiation from sunlight damages skin cells' DNA. Wavelengths in the UVB range are absorbed by DNA and can induce mutagenic lesions such as pyrimidine dimers. On the other hand, genotoxic effects of solar UVA are mainly mediated by the activation of endogenous photosensitize...

journal_title：Journal of the American Academy of Dermatology

authors： Marrot L,Meunier JR

更新日期：2008-05-01 00:00:00

abstract：BACKGROUND:Topical immunotherapy has been used in the treatment of children with alopecia areata with encouraging results. OBJECTIVE:Our purpose was to determine the long-term results in 33 children with severe alopecia areata treated with topical immunotherapy. METHODS:From 1983 to 1989 we treated 33 children with t...

journal_title：Journal of the American Academy of Dermatology

authors： Tosti A,Guidetti MS,Bardazzi F,Misciali C

更新日期：1996-08-01 00:00:00

abstract：:The use of the various forms of phototherapy remains an essential treatment option for psoriasis vulgaris. Expertise concerning the mechanisms involved with the actions of therapeutic ultraviolet light and the proper delivery of office-based treatments resides within the specialty of dermatology. New therapies for the...

journal_title：Journal of the American Academy of Dermatology

authors： Zanolli M

更新日期：2003-08-01 00:00:00

abstract：BACKGROUND:In recent years, increasing emphasis has been placed on value-based health care delivery. Dermatology must develop performance measures to judge the quality of services provided. The implementation of a national complication registry is one such method of tracking surgical outcomes and monitoring the safety ...

journal_title：Journal of the American Academy of Dermatology

authors： Council ML,Alam M,Gloster HM Jr,Bordeaux JS,Carroll BT,Leitenberger JJ,Wisco OJ,Maher IA

更新日期：2016-04-01 00:00:00

abstract：:A new technic is described for more accurately checking the surgical margins of skin tumors removed by standard surgical excision. Vertical sections of surgical specimens represent check points of the margin only 7 microns thick. This means most of the surgical margin is not checked microscopically, allowing small tum...

journal_title：Journal of the American Academy of Dermatology

authors： Schultz BC,Roenigk HH Jr

更新日期：1982-10-01 00:00:00

abstract：:Urticaria is one of the more common skin conditions seen by physicians. Physical agents are an important cause of urticaria, with pressure or shearing forces being the most common. Dermographism is due to a combination of pressure and shearing forces and is present in a large number of healthy individuals. The purpose...

journal_title：Journal of the American Academy of Dermatology

authors： Wong RC,Fairley JA,Ellis CN

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:Indoor tanning may increase the risk of melanoma and other health problems. Frequent users of indoor tanning facilities may be at particularly high risk. OBJECTIVE:In study 1 our purpose was to assess the prevalence and nature of indoor tanning advertisements; in study 2 we aimed to assess tanning facility ...

journal_title：Journal of the American Academy of Dermatology

authors： Kwon HT,Mayer JA,Walker KK,Yu H,Lewis EC,Belch GE

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVE:We sought to assess the difference in lesion management between combined examination (naked-eye and dermoscopy) and conventional naked-eye examination in evaluations for melanoma; and to assess the impact on patient treatment of facilities for digital follow-up of diagnostically equivocal lesions. METHODS:We...

journal_title：Journal of the American Academy of Dermatology

authors： Carli P,de Giorgi V,Chiarugi A,Nardini P,Weinstock MA,Crocetti E,Stante M,Giannotti B

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Significant unmet need exists for long-term treatment of moderate to severe atopic dermatitis (AD). OBJECTIVE:To assess the long-term safety and efficacy of dupilumab in patients with AD. METHODS:This ongoing, multicenter, open-label extension study (NCT01949311) evaluated long-term dupilumab treatment in ...

journal_title：Journal of the American Academy of Dermatology

authors： Deleuran M,Thaçi D,Beck LA,de Bruin-Weller M,Blauvelt A,Forman S,Bissonnette R,Reich K,Soong W,Hussain I,Foley P,Hide M,Bouaziz JD,Gelfand JM,Sher L,Schuttelaar MLA,Wang C,Chen Z,Akinlade B,Gadkari A,Eckert L,Da

更新日期：2020-02-01 00:00:00

abstract：:Hyperpigmentation, pulmonary infiltration, and erythema nodosum occurred in a patient receiving long-term minocycline therapy. Bronchoalveolar lavage revealed both a neutrophilic and an eosinophilic alveolitis. The pulmonary and systemic symptoms promptly resolved after discontinuation of minocycline. ...

journal_title：Journal of the American Academy of Dermatology

authors： Bridges AJ,Graziano FM,Calhoun W,Reizner GT

更新日期：1990-05-01 00:00:00

abstract：BACKGROUND:In recent years there has been an increasing focus on human subject protection and on documentation of ethical review in published clinical research. The JAAD clearly states in its instructions to authors, which adhere to the guidelines set forth by the International Committee of Medical Journal Editors, "st...

journal_title：Journal of the American Academy of Dermatology

authors： Perkins AC,Choi JM,Kimball AB

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:In patients with malignancy-associated Sweet syndrome, a thorough evaluation for leukemia cutis should be considered. OBJECTIVE:We sought to describe the clinicopathologic characteristics of histiocytoid Sweet syndrome. METHODS:We retrospectively identified patients with histiocytoid Sweet syndrome at our ...

journal_title：Journal of the American Academy of Dermatology

authors： Chavan RN,Cappel MA,Ketterling RP,Wada DA,Rochet NM,Knudson R,Gibson LE

更新日期：2014-06-01 00:00:00

abstract：:Fifty-four male and female patients with suspected colonic disease were examined for the presence of acrochordons prior to colonoscopy. Thirty-five of these patients (65%) had skin tags and twenty-six (48%) were found to have colonic polyps. In this study patients with acrochordons were significantly (p less than 0.00...

journal_title：Journal of the American Academy of Dermatology

authors： Beitler M,Eng A,Kilgour M,Lebwohl M

更新日期：1986-06-01 00:00:00

abstract：:Many cutaneous diseases have been reported in patients with human immunodeficiency virus infection. We report two patients with pityriasis rubra pilaris and human immunodeficiency virus infection. In one patient, the onset of pityriasis rubra pilaris preceded the discovery of human immunodeficiency virus infection. In...

journal_title：Journal of the American Academy of Dermatology

authors： Blauvelt A,Nahass GT,Pardo RJ,Kerdel FA

更新日期：1991-05-01 00:00:00

abstract：:The effects of cyclosporine were studied in nine patients suffering from pemphigus vulgaris. Of four patients treated with cyclosporine alone, only one cleared. Of four corticosteroid-resistant pemphigus vulgaris patients, all improved after cyclosporine addition to corticosteroids. The last patient treated from the b...

journal_title：Journal of the American Academy of Dermatology

authors： Barthelemy H,Frappaz A,Cambazard F,Mauduit G,Rouchouse B,Kanitakis J,Souteyrand P,Claudy AL,Thivolet J

更新日期：1988-06-01 00:00:00

abstract：:Botryomycosis in an uncommon chronic bacterial infection that mimics fungal disease clinically and histologically. Microscopically the hallmark of the disease is the presence of fungus-like granules in which the causative organism is embedded. A patient with typical cutaneous botryomycosis is presented, along with the...

journal_title：Journal of the American Academy of Dermatology

authors： Brunken RC,Lichon-Chao N,van der Broek H

更新日期：1983-09-01 00:00:00

abstract：:Squamous cell carcinoma of the penis is almost exclusively a lesion of uncircumcised older men. It represents about 1% of cancers in men in the United States and 11% to 12% of all cancers in men in countries where circumcision is not routinely practiced. Verrucous carcinoma is an uncommon variant that accounts for onl...

journal_title：Journal of the American Academy of Dermatology

authors： Kanik AB,Lee J,Wax F,Bhawan J

更新日期：1997-08-01 00:00:00

abstract：:Clinical trials are critical for the development of new therapies in dermatology, and their results help determine US Food and Drug Administration (FDA) approval and guide care. Of special relevance is the clinical trial efficacy end point, the metric from which statistically significant outcome is derived. Clinicians...

journal_title：Journal of the American Academy of Dermatology

authors： Wei EX,Kirsner RS,Eaglstein WH

更新日期：2016-07-01 00:00:00