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Cutaneous T cell lymphoma: mycosis fungoides, Sézary syndrome, and other variants.

Abstract：

:Cutaneous T cell lymphoma (CTCL) is a clinically and immunologically defined neoplasm which encompasses epidermotropic (mycosis fungoides, Sézary syndrome) and nonepidermotropic variants. A natural evolution apparently occurs from the epidermotropic to the nonepidermotropic form. In this review, cellular properties of the neoplastic cells are correlated with specific clinical observations, and recent therapeutic advances are discussed. Advances in our understanding of the pathogenesis of CTCL, including preliminary evidence suggesting that keratinocytes may elaborate a hormonal substance capable of inducing T lymphocyte differentiation, are discussed.

journal_name

J Am Acad Dermatol

journal_title

Journal of the American Academy of Dermatology

authors

Edelson RL

doi

10.1016/s0190-9622(80)80385-9

subject

Has Abstract

pub_date

1980-02-01 00:00:00

pages

89-106

issue

2

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(80)80385-9

journal_volume

2

pub_type

杂志文章,评审

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