Pyoderma gangrenosum: a review and update on new therapies.

abstract：:During the past two decades, systemic μ-opioid receptor antagonists (MORA) have been used in the treatment of various forms of chronic pruritus. In a number of case reports, case series, and controlled trials, treatment with MORA has demonstrated considerable antipruritic effects. In double-blind controlled studies, s...

journal_title：Journal of the American Academy of Dermatology

authors： Phan NQ,Bernhard JD,Luger TA,Ständer S

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:This study was undertaken to evaluate the effectiveness and safety of the 577 nm pulsed dye laser in the treatment of various vascular lesions of the face. OBJECTIVE:Our purpose was to make observations on the effects of different variables that could affect response. METHODS:Ninety-two adults with telangi...

journal_title：Journal of the American Academy of Dermatology

authors： Gonzalez E,Gange RW,Momtaz KT

更新日期：1992-08-01 00:00:00

abstract：BACKGROUND:The association of atopic dermatitis (AD) with other allergic diseases has been extensively studied; however, there is a lack of reports focusing on long-term studies of the clinical and allergometric evaluations observed during the course of AD in respect to its evolution and association with allergic respo...

journal_title：Journal of the American Academy of Dermatology

authors： Ricci G,Patrizi A,Baldi E,Menna G,Tabanelli M,Masi M

更新日期：2006-11-01 00:00:00

abstract：:Disseminated histoplasmosis is being diagnosed more frequently in persons infected with the human immunodeficiency virus and is often the initial manifestation of the acquired immunodeficiency syndrome (AIDS). Disease-related cutaneous features of HIV-associated disseminated histoplasmosis are defined as mucocutaneous...

journal_title：Journal of the American Academy of Dermatology

authors： Cohen PR,Bank DE,Silvers DN,Grossman ME

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Condyloma acuminatum are common lesions caused by human papillomavirus (HPV). HPV is associated with many human cancers, and a vaccine now prevents infection with high-risk HPV. However, eradication of established disease is difficult, indicating that these lesions are capable of local immunosuppression. OB...

journal_title：Journal of the American Academy of Dermatology

authors： Le Poole C,Denman CJ,Arbiser JL

更新日期：2008-12-01 00:00:00

abstract：:We report a case of a 10-month-old male infant with GM1 type 1 gangliosidosis who also had hyperpigmented macules and patches. Light and electron microscopic findings correlated with previously published reports on findings in skin biopsy specimens of patients with lipid storage disorders. The hyperpigmented macules a...

journal_title：Journal of the American Academy of Dermatology

authors： Selsor LC,Lesher JL Jr

更新日期：1989-05-01 00:00:00

abstract：:Pyoderma gangrenosum, severe acne, and suppurative hidradenitis (PASH) syndrome can prove refractory to treatment and is characterized by relapses and recurrences. The combination of antibiotic therapy and surgery can produce success in the management of the syndrome. Acute treatment is required, but maintenance thera...

journal_title：Journal of the American Academy of Dermatology

authors： Join-Lambert O,Duchatelet S,Delage M,Miskinyte S,Coignard H,Lemarchand N,Alemy-Carreau M,Lortholary O,Nassif X,Hovnanian A,Nassif A

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Keratoacanthomas usually occur spontaneously as a single rapidly growing tumor on sun-exposed skin. Multiple keratoacanthomas are rarely seen. Keratoacanthomas may also develop after trauma, laser resurfacing, radiation therapy, and at the donor site after skin grafting. OBJECTIVE:We report 6 cases of kerat...

journal_title：Journal of the American Academy of Dermatology

authors： Goldberg LH,Silapunt S,Beyrau KK,Peterson SR,Friedman PM,Alam M

更新日期：2004-05-01 00:00:00

abstract：:The antiphospholipid syndrome (APS) is an autoimmune disorder characterized by the occurrence of arterial and/or venous thromboembolic events and obstetric complications in the setting of circulating antiphospholipid antibodies. Dermatologic manifestations are commonly seen in APS with almost half of the patients exhi...

journal_title：Journal of the American Academy of Dermatology

authors： Kriseman YL,Nash JW,Hsu S

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Rosacea is a chronic inflammatory skin disease. Inflammation plays a prominent role in atherosclerosis and its complications. OBJECTIVE:We sought to investigate the associations of rosacea with cardiovascular disease risk factors and cardiovascular diseases from a nationwide population-based database. METH...

journal_title：Journal of the American Academy of Dermatology

authors： Hua TC,Chung PI,Chen YJ,Wu LC,Chen YD,Hwang CY,Chu SY,Chen CC,Lee DD,Chang YT,Liu HN

更新日期：2015-08-01 00:00:00

abstract：:Chronic mucocutaneous candidiasis is a complex disorder in which patients have chronic and recurrent Candida albicans infections of the skin, nails, and mucous membranes. There are several subgroups of patients with chronic mucocutaneous candidiasis, and these can be identified by associated disorders such as autoimmu...

journal_title：Journal of the American Academy of Dermatology

authors： Kirkpatrick CH

更新日期：1994-09-01 00:00:00

abstract：:Transillumination with a high-intensity fiberoptic light source is an effective means of diagnosing pneumothoraces and localizing arteries and veins for blood sampling. It has been used for these purposes in neonatal intensive care units since the 1970s. Thermal burns were reported in association with the technique in...

journal_title：Journal of the American Academy of Dermatology

authors： Sajben FP,Gibbs NF,Friedlander SF

更新日期：1999-08-01 00:00:00

abstract：:The primary serum proteinase inhibitor is alpha 1-antitrypsin, and deficiency of this enzyme has been associated with a variety of systemic and cutaneous disorders. We report cutaneous vasculitis in a 49-year-old man with alpha 1-antitrypsin deficiency. His condition persisted despite treatment with colchicine, predni...

journal_title：Journal of the American Academy of Dermatology

authors： Dowd SK,Rodgers GC,Callen JP

更新日期：1995-11-01 00:00:00

abstract：BACKGROUND:The tumor necrosis factor (TNF) inhibitor etanercept has been demonstrated to be safe and effective for treating chronic plaque psoriasis in 3 clinical trials. OBJECTIVES:To refine efficacy results for etanercept on the basis of a larger population size through the integration of the 3 studies, and to deter...

journal_title：Journal of the American Academy of Dermatology

authors： Gordon K,Korman N,Frankel E,Wang H,Jahreis A,Zitnik R,Chang T

更新日期：2006-03-01 00:00:00

abstract：:A case is presented in which a patient experienced the development of both Dupuytren's disease and Peyronie's disease after single episodes of sports-related trauma. These disorders and other fibromatoses are linked not only by similar pathologic features but by increased frequency of simultaneous occurrence. Some gen...

journal_title：Journal of the American Academy of Dermatology

authors： Connelly TJ

更新日期：1999-07-01 00:00:00

abstract：BACKGROUND:The Melasma Area and Severity Index (MASI), the most commonly used outcome measure for melasma, has not been validated. OBJECTIVE:We sought to determine the reliability and validity of the MASI. METHODS:After standardized training, 6 raters independently rated 21 patients with mild to severe melasma once d...

journal_title：Journal of the American Academy of Dermatology

authors： Pandya AG,Hynan LS,Bhore R,Riley FC,Guevara IL,Grimes P,Nordlund JJ,Rendon M,Taylor S,Gottschalk RW,Agim NG,Ortonne JP

更新日期：2011-01-01 00:00:00

abstract：:We hereby report a case presenting a rare form of secondary syphilis with an unusual nodular eruption accompanied by pruritus and generalized lymphadenopathy, bearing a striking resemblance to lymphoma. The histologic picture was also misleading and was compatible with lymphocytoma cutis. The diagnosis was eventually ...

journal_title：Journal of the American Academy of Dermatology

authors： Hodak E,David M,Rothem A,Bialowance M,Sandbank M

更新日期：1987-11-01 00:00:00

abstract：:This is the second reported case of minocycline-induced Sweet's syndrome (and the first such case to appear in the American literature). The syndrome developed in a 32-year-old man 10 days after minocycline therapy for acne was begun and resolved rapidly after discontinuation of the medication and start of oral predni...

journal_title：Journal of the American Academy of Dermatology

authors： Thibault MJ,Billick RC,Srolovitz H

更新日期：1992-11-01 00:00:00

abstract：BACKGROUND:The administration of a local anesthetic is often painful. OBJECTIVE:The purpose of this study was to determine whether rapidly shaking and pinching the skin during local anesthetic administration decreases pain perception. METHODS:The skin at the intended site of lidocaine injection was rapidly pinched be...

journal_title：Journal of the American Academy of Dermatology

authors： Fosko SW,Gibney MD,Harrison B

更新日期：1998-07-01 00:00:00

abstract：:Vulvar melanosis is a condition in which intensely pigmented irregular macules, clinically mimicking malignant melanoma, appear on the vulva. A biopsy specimen shows only marked lower epidermal pigmentation without any melanocytic atypia or nesting. The process is benign, and reassurance is the only treatment. ...

journal_title：Journal of the American Academy of Dermatology

authors： Rudolph RI

更新日期：1990-11-01 00:00:00

abstract：:A 60-year-old man with postpolycythemic myeloid metaplasia developed acute neutrophilic dermatosis (Sweet's syndrome), which responded to systemic steroid therapy. Six months later he developed acute myelogenous blast crisis refractory to leukemic induction therapy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Horan MP,Redmond J,Gehle D,Dabe IB,Fort SL

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Dermatophytic infections of the fingernail can be effectively treated with oral antifungal agents; however, a long duration of treatment, generally several months, is required for cure. OBJECTIVE:Our purpose was to compare the efficacies of short-duration treatment with terbinafine and griseofulvin in the m...

journal_title：Journal of the American Academy of Dermatology

authors： Haneke E,Tausch I,Bräutigam M,Weidinger G,Welzel D

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Dengue fever is the most common identifiable cause of acute febrile illness among travelers returning from South America, South Central Asia, Southeast Asia, and the Caribbean. Although the characteristic exanthem of dengue fever occurs in up to 50% of patients, few descriptions of it are found in the dermat...

journal_title：Journal of the American Academy of Dermatology

authors： Pincus LB,Grossman ME,Fox LP

更新日期：2008-02-01 00:00:00

abstract：:Fifteen patients with toxic epidermal necrolysis (TEN) were studied. In all of them the TEN was related to drug ingestion and believed to be drug-induced. The drugs implicated include pyrazolone derivatives, allopurinol, barbiturates, tetracycline, phenytoin, and penicillamine. Possible etiologic co-factors are infect...

journal_title：Journal of the American Academy of Dermatology

authors： Chan HL

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:Recipients of organ transplant who are immunosuppressed are at greatly increased risk of nonmelanoma skin cancers compared with the general population, but their risk of appendageal tumors is unknown. OBJECTIVE:Our aim was to conduct a systematic examination of cutaneous appendageal tumors arising in recipi...

journal_title：Journal of the American Academy of Dermatology

authors： Harwood CA,McGregor JM,Swale VJ,Proby CM,Leigh IM,Newton R,Khorshid SM,Cerio R

更新日期：2003-03-01 00:00:00

abstract：:Metastasis to the skin from cervical carcinoma is relatively uncommon. Herein we present a 41-year-old woman with a history of cervical carcinoma with severe facial erythematous swelling and telangiectasia. She was initially treated for cellulitis without improvement. A skin biopsy specimen revealed widespread intrava...

journal_title：Journal of the American Academy of Dermatology

authors： Yang HI,Lee MC,Kuo TT,Hong HS

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND:Hypopigmentation is an adverse outcome associated with carbon-dioxide (CO(2)) laser resurfacing. A 90-microsecond pulse produces a more favorable postoperative course of healing, erythema, and pain compared with a 900-microsecond dwell time. The rate of hypopigmentation after 90-microsecond pulsed CO(2) resu...

journal_title：Journal of the American Academy of Dermatology

authors： Lewis KG,Nahm WK,Schmidt AN,Moy RL

更新日期：2004-02-01 00:00:00

abstract：BACKGROUND:Hyperlipidemia has received little attention as a side effect of cyclosporine therapy for severe psoriasis. OBJECTIVE:We report changes in fasting serum lipids in patients treated with low-dose oral cyclosporine for psoriasis and discuss their significance. METHODS:Twenty-two patients with severe, recalcit...

journal_title：Journal of the American Academy of Dermatology

authors： Stiller MJ,Pak GH,Kenny C,Jondreau L,Davis I,Wachsman S,Shupack JL

更新日期：1992-09-01 00:00:00

abstract：BACKGROUND:Scleredema adultorum (SA) is a rare connective tissue disorder for which no treatment has proven to be effective. OBJECTIVE:Our purpose was to determine the effect of bath-PUVA therapy on SA. METHODS:Three patients were treated. Clinical evaluation of skin induration and thickness as well as ultrasonograph...

journal_title：Journal of the American Academy of Dermatology

authors： Hager CM,Sobhi HA,Hunzelmann N,Wickenhauser C,Scharenberg R,Krieg T,Scharffetter-Kochanek K

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Localized lymphedema is a nonneoplastic condition associated with obesity and predominantly involving the legs. This condition has distinctive clinical and histologic features and only rarely has been mentioned in the dermatologic literature. OBJECTIVE:We sought to evaluate the clinical and histopathologic ...

journal_title：Journal of the American Academy of Dermatology

authors： Plaza JA,Requena L,Kazakov DV,Vega E,Kacerovska D,Reyes G,Michal M,Suster S,Sangueza M

更新日期：2014-08-01 00:00:00