Chronic mucocutaneous candidiasis.

abstract：:Anti-epiligrin cicatricial pemphigoid is an autoimmune subepithelial blistering disorder of mucous membranes and skin. By immunoblot analyses, sera of most patients with antiepiligrin cicatricial pemphigoid have been shown to react specifically with the alpha3 chain of laminin 5. We describe the first patient with ant...

journal_title：Journal of the American Academy of Dermatology

authors： Fujimoto W,Toi Y,Okazaki F,Lazarova Z,Yancey KB,Arata J

更新日期：1999-04-01 00:00:00

abstract：:Eosinophilic spongiosis has a distinctive but not diagnostic histologic pattern of the epidermis. This pattern may be seen in a wide variety of clinical disorders. We have observed it most commonly in bullous pemphigoid, particularly the urticarial stage. In most biopsy specimens that show eosinophilic spongiosis, add...

journal_title：Journal of the American Academy of Dermatology

authors： Crotty C,Pittelkow M,Muller SA

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND:There are multiple therapeutic options for the treatment of moderate to severe psoriasis. The process of choosing among potential treatment options requires both the physician and the patient to weigh the benefits of individual modalities against their potential risks. Traditional systemic therapies for psor...

journal_title：Journal of the American Academy of Dermatology

authors： Patel RV,Clark LN,Lebwohl M,Weinberg JM

更新日期：2009-06-01 00:00:00

abstract：:Fifteen patients with toxic epidermal necrolysis (TEN) were studied. In all of them the TEN was related to drug ingestion and believed to be drug-induced. The drugs implicated include pyrazolone derivatives, allopurinol, barbiturates, tetracycline, phenytoin, and penicillamine. Possible etiologic co-factors are infect...

journal_title：Journal of the American Academy of Dermatology

authors： Chan HL

更新日期：1984-06-01 00:00:00

abstract：BACKGROUND:Associations between gluten intake and psoriasis, psoriatic arthritis, and atopic dermatitis are poorly understood. OBJECTIVE:To determine whether increased gluten intake is associated with incident psoriasis, psoriatic arthritis, and atopic dermatitis. METHODS:Cohort studies among women in Nurses' Health ...

journal_title：Journal of the American Academy of Dermatology

authors： Drucker AM,Qureshi AA,Thompson JM,Li T,Cho E

更新日期：2020-03-01 00:00:00

abstract：:The role of estrogens in the development of skin cancer is controversial. Sex steroids have a profound effect on the epidermis and epidermal appendages. Estradiol in pharmacologic doses has been reported to stimulate basal cell carcinoma in an animal model. Sex hormones act by means of a specific protein receptor. In ...

journal_title：Journal of the American Academy of Dermatology

authors： Rogers GS,Flowers JL,Pollack SV,McCarty KS Jr

更新日期：1988-05-01 00:00:00

abstract：:Vohwinkel's syndrome or keratoderma hereditaria mutilans is a diffuse, honeycombed, palmar, and plantar keratosis usually accompanied by pseudoainhum near the distal interphalangeal creases. The mutilating keratoderma associated with sensorineural hearing loss is thought to have an etiologic basis, resting on a mutati...

journal_title：Journal of the American Academy of Dermatology

authors： Solis RR,Diven DG,Trizna Z

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Some studies have purported to link isotretinoin prescribed for acne with the development of inflammatory bowel disease (IBD). OBJECTIVE:We sought to identify existence of disproportionate attorney-initiated reporting of isotretinoin-associated IBD in the Food and Drug Administration Adverse Event Reporting...

journal_title：Journal of the American Academy of Dermatology

authors： Stobaugh DJ,Deepak P,Ehrenpreis ED

更新日期：2013-09-01 00:00:00

abstract：:This prospective study (1977-1980) of cosmetic adverse reactions by eleven dermatologists identified 487 cases of cosmetic-induced dermatitis. Approximately half of the cases were covert in nature. Eight percent were due to allergic contact dermatitis; the face, eye, and upper arm were the most involved sites. Skin ca...

journal_title：Journal of the American Academy of Dermatology

authors： Eiermann HJ,Larsen W,Maibach HI,Taylor JS

更新日期：1982-05-01 00:00:00

abstract：:We report a case of a 10-month-old male infant with GM1 type 1 gangliosidosis who also had hyperpigmented macules and patches. Light and electron microscopic findings correlated with previously published reports on findings in skin biopsy specimens of patients with lipid storage disorders. The hyperpigmented macules a...

journal_title：Journal of the American Academy of Dermatology

authors： Selsor LC,Lesher JL Jr

更新日期：1989-05-01 00:00:00

abstract：:The presence of immunoglobulin and complement deposits in the skin of three patients with papular urticaria suggests that these lesions may be due to a cutaneous vasculitis. These deposits were most frequently found in biopsy specimens taken from lesions within 24 hours of their development. The presence of granular d...

journal_title：Journal of the American Academy of Dermatology

authors： Heng MC,Kloss SG,Haberfelde GC

更新日期：1984-06-01 00:00:00

abstract：:We hereby report a case presenting a rare form of secondary syphilis with an unusual nodular eruption accompanied by pruritus and generalized lymphadenopathy, bearing a striking resemblance to lymphoma. The histologic picture was also misleading and was compatible with lymphocytoma cutis. The diagnosis was eventually ...

journal_title：Journal of the American Academy of Dermatology

authors： Hodak E,David M,Rothem A,Bialowance M,Sandbank M

更新日期：1987-11-01 00:00:00

abstract：:The evaluation of skin findings is critical in identifying many types of injury, whether self- inflicted or accidentally or intentionally inflicted. Specific causes of injury include homicide, abuse, neglect, assault, self-inflicted injury, suicide, torture, poisoning, and bioterrorism. Forensic findings in hair and n...

journal_title：Journal of the American Academy of Dermatology

authors： Reddy K,Lowenstein EJ

更新日期：2011-05-01 00:00:00

abstract：:Costs for dermatitis can be evaluated against the costs and potential benefits of patch testing on the basis of data available from several sources. Consideration of cost for an individual patient suggests that costs become neutral and benefits become positive if the dermatitis is persistent and multiple physician vis...

journal_title：Journal of the American Academy of Dermatology

authors： Rietschel RL

更新日期：1989-10-01 00:00:00

abstract：:Scleromyxedema is a rare cutaneous disease with occasional systemic involvement and characteristic poor response to treatment. A case of scleromyxedema associated with renal scleroderma and acute psychosis is presented, along with a review of treatment and associated internal disorders. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kantor GR,Bergfeld WF,Katzin WE,Reynolds OD,Biscardi AP,Lobur DM,Box TA,Schreiber MJ Jr,Ratliff NB

更新日期：1986-05-01 00:00:00

abstract：BACKGROUND:Surgeons use absorbable and nonabsorbable sutures for epidermal wound closure. No large, randomized studies have compared the effect of these suture types on facial scar appearance. OBJECTIVE:To assess postsurgical facial scar appearance using either rapidly absorbable polyglactin 910 or nylon for epidermal...

journal_title：Journal of the American Academy of Dermatology

authors： Moran B,Humphrey S,Seal A,Berkowitz J,Zloty D

更新日期：2020-11-01 00:00:00

abstract：:Mycobacterium avium complex, a common opportunistic pathogen among patients with AIDS, usually manifests as disseminated disease involving the lung, lymph nodes, and gastrointestinal tract. Primary cutaneous infections with M avium complex are extremely rare, and most cutaneous lesions are caused by dissemination. Cut...

journal_title：Journal of the American Academy of Dermatology

authors： Kayal JD,McCall CO

更新日期：2002-11-01 00:00:00

abstract：:Hirsutism in women is frequently associated with increased levels of androgens. Studies of biochemical changes, however, have yielded conflicting results. This study compares the findings in 30 hirsute women with normal menses and those of 30 hirsute women with abnormal cycles. Of the women with abnormal menstruation,...

journal_title：Journal of the American Academy of Dermatology

authors： Redmond GP,Bergfeld W,Gupta M,Bedocs NM,Skibinski C,Gidwani G

更新日期：1990-01-01 00:00:00

abstract：BACKGROUND:The current standard tool for diagnosing allergic contact dermatitis (ACD) in the United States is the T.R.U.E. test panels, which consist of 23 allergens. Previous studies have raised concern regarding the adequacy of these panels in fully assessing patients with possible ACD. OBJECTIVE:We sought to examin...

journal_title：Journal of the American Academy of Dermatology

authors： Saripalli YV,Achen F,Belsito DV

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Although rare in the general population, highly penetrant germline mutations in CDKN2A are responsible for 5%-40% of melanoma cases reported in melanoma-prone families. We sought to determine whether MELPREDICT was generalizable to a global series of families with melanoma and whether performance improvement...

journal_title：Journal of the American Academy of Dermatology

authors： Taylor NJ,Mitra N,Qian L,Avril MF,Bishop DT,Bressac-de Paillerets B,Bruno W,Calista D,Cuellar F,Cust AE,Demenais F,Elder DE,Gerdes AM,Ghiorzo P,Goldstein AM,Grazziotin TC,Gruis NA,Hansson J,Harland M,Hayward NK,Ho

更新日期：2019-08-01 00:00:00

abstract：:During the past two decades, systemic μ-opioid receptor antagonists (MORA) have been used in the treatment of various forms of chronic pruritus. In a number of case reports, case series, and controlled trials, treatment with MORA has demonstrated considerable antipruritic effects. In double-blind controlled studies, s...

journal_title：Journal of the American Academy of Dermatology

authors： Phan NQ,Bernhard JD,Luger TA,Ständer S

更新日期：2010-10-01 00:00:00

abstract：BACKGROUND:Epidermolysis bullosa simplex is a skin-blistering disorder caused by mutations in keratin (K)14 or K5. Treatment with nuclear factor (erythroid-derived 2)-like 2 inducer sulforaphane ameliorated skin blistering in Krt14-null mice, correlating with induction of K17. To be therapeutically useful for epidermol...

journal_title：Journal of the American Academy of Dermatology

authors： Kerns ML,Guss L,Fahey J,Cohen B,Hakim JM,Sung S,Lu RG,Coulombe PA

更新日期：2017-03-01 00:00:00

abstract：:Two cases of semicircular lipoatrophy and one of annular lipoatrophy are presented. The reasons why semicircular lipoatrophy, annular lipoatrophy, and annular atrophy of the ankles seem to be different clinical entities are discussed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Rongioletti F,Rebora A

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Dermatopathologists often are asked by clinicians to report margins on punch excisions of melanocytic lesions. OBJECTIVE:We sought to determine the adequacy of surgical margins on melanocytic lesions submitted with intention of complete excision using punch removal technique. METHODS:We conducted prospecti...

journal_title：Journal of the American Academy of Dermatology

authors： Chang TT,Somach SC,Wagamon K,Somani AK,Pomeranz J,Jaworsky C,Bass J,Winfield HL,Sigel JE,Rosenberg AS

更新日期：2009-06-01 00:00:00

abstract：:Blister beetle dermatosis is a distinctive vesiculobullous eruption that occurs after contact with three major groups of beetles (Order: Coleoptera). It is caused by a vesicant chemical contained in the body fluids of the beetles. The smallest and least known family is the Oedemeridae. Although there are few reference...

journal_title：Journal of the American Academy of Dermatology

authors： Nicholls DS,Christmas TI,Greig DE

更新日期：1990-05-01 00:00:00

abstract：:We report the first case of acral localized acquired cutis laxa. The skin laxity was preceded by swelling of the fingers and toes and by the appearance of papular urticaria. Dapsone therapy was effective in controlling the swelling. Examination of skin biopsy specimens showed fragmentation and almost total loss of ela...

journal_title：Journal of the American Academy of Dermatology

authors： Fisher BK,Page E,Hanna W

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND:Keloid scars can itch and hurt, but little is known about the characteristics of these symptoms in keloids. Because itch and pain are carried by small nerve fibers, abnormal function of these fibers could be an explanation for such phenomena. OBJECTIVE:We sought to assess the characteristics of itch and pai...

journal_title：Journal of the American Academy of Dermatology

authors： Lee SS,Yosipovitch G,Chan YH,Goh CL

更新日期：2004-12-01 00:00:00

abstract：BACKGROUND:Melanoma in African Americans is rare, and the diagnosis is often delayed, leading to advanced presentation and poor prognosis. OBJECTIVE:The purpose of this retrospective study is to determine whether African American patients diagnosed with melanoma at the Washington Hospital Center were initially seen wi...

journal_title：Journal of the American Academy of Dermatology

authors： Byrd KM,Wilson DC,Hoyler SS,Peck GL

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Ipilimumab is a human antibody that inhibits cytotoxic T-lymphocyte-associated antigen 4, leading to increases in T-cell activation and interleukin 2 secretion and has been approved for the treatment of advanced melanoma. Dermatologic adverse events such as rash, pruritus, and vitiligo have been reported in ...

journal_title：Journal of the American Academy of Dermatology

authors： Minkis K,Garden BC,Wu S,Pulitzer MP,Lacouture ME

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Antidrug antibodies (ADAs) may change pharmacokinetic or pharmacodynamic profiles of biologic therapies, potentially decreasing efficacy. OBJECTIVE:To evaluate the potential effects of brodalumab immunogenicity on safety, efficacy, and retreatment. METHODS:Data from 1 phase 2 and 3 phase 3 studies of broda...

journal_title：Journal of the American Academy of Dermatology

authors： Bagel J,Lebwohl M,Israel RJ,Jacobson A

更新日期：2020-02-01 00:00:00