Porphyria cutanea tarda in association with human immunodeficiency virus infection in a hemophiliac.

abstract：BACKGROUND:Psoriasis and migraine are common conditions with potential overlap of pathophysiological mechanisms. Both these diseases have been associated with increased cardiovascular risk but little is known about their interplay. OBJECTIVE:We sought to investigate the link between psoriasis, and the risk of new-onse...

journal_title：Journal of the American Academy of Dermatology

authors： Egeberg A,Mallbris L,Hilmar Gislason G,Skov L,Riis Hansen P

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The continuous increase in the US population older than 65 years and the chronic course of psoriasis make management of psoriasis in the elderly an important health care problem. OBJECTIVE:We sought to develop a treatment algorithm for patients with psoriasis who are older than 65 years. METHODS:A systemat...

journal_title：Journal of the American Academy of Dermatology

authors： Grozdev IS,Van Voorhees AS,Gottlieb AB,Hsu S,Lebwohl MG,Bebo BF Jr,Korman NJ,National Psoriasis Foundation.

更新日期：2011-09-01 00:00:00

abstract：:The PA Patch, a new multiple-antigen, predispensed patch testing device, was compared to the Finn Chamber in subjects with previous positive patch tests. After pressing the PA Patch well, the PA Patch performed as well as the Finn Chamber in nine subjects tested. ...

journal_title：Journal of the American Academy of Dermatology

authors： Marks JG Jr,Westheim A,Snipes W

更新日期：1987-05-01 00:00:00

abstract：:Angioma serpiginosum is a rare condition that involves both the proliferation and dilatation of superficial blood vessels in the skin. It classically begins in childhood, is more common in females, and is asymptomatic. Typical lesions appear on the extremities and are often asymmetric. We report a case of angioma serp...

journal_title：Journal of the American Academy of Dermatology

authors： Katta R,Wagner A

更新日期：2000-02-01 00:00:00

abstract：:We performed a 22-month trial of topical tretinoin (retinoic acid) in the treatment of photoaging. Thirty patients participated in a 4-month, randomized, blinded, vehicle-controlled study that has been reported previously; 21 patients continued tretinoin therapy on an open-label basis, participating in the study for a...

journal_title：Journal of the American Academy of Dermatology

authors： Ellis CN,Weiss JS,Hamilton TA,Headington JT,Zelickson AS,Voorhees JJ

更新日期：1990-10-01 00:00:00

abstract：:An association between HLA-DR1 and the development of multiple basal cell carcinomas was detected in southern Australia. A reduction in HLA-DR4 was found in patients with basal cell carcinoma compared with a local control group. The relative risk for HLA-DR1 was 2.1, which was lower than that for persons in farther co...

journal_title：Journal of the American Academy of Dermatology

authors： Czarnecki D,Lewis A,Nicholson I,Tait B

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Moderate-to-severe atopic dermatitis (AD) is increasingly recognized as a systemic disease, largely due to proteomic blood studies. There are growing efforts to develop AD biomarkers using minimal tissues. OBJECTIVE:To characterize the AD skin proteomic signature and its relationship with the blood proteome...

journal_title：Journal of the American Academy of Dermatology

authors： Pavel AB,Zhou L,Diaz A,Ungar B,Dan J,He H,Estrada YD,Xu H,Fernandes M,Renert-Yuval Y,Krueger JG,Guttman-Yassky E

更新日期：2020-03-01 00:00:00

abstract：BACKGROUND:Necrobiotic xanthogranuloma (NXG) is a rare histiocytic disorder of unknown origin. OBJECTIVE:We conducted an investigation of skin biopsy specimens from 7 patients with NXG for the presence of Borrelia by focus-floating microscopy. METHODS:Focus-floating microscopy is a recently described, modified immuno...

journal_title：Journal of the American Academy of Dermatology

authors： Zelger B,Eisendle K,Mensing C,Zelger B

更新日期：2007-12-01 00:00:00

abstract：:The incidence of malignant melanoma is increasing faster than that of any other cancer. It is important to identify subsets of the population at high risk of its development so that they can be observed more closely to identify early melanomas when they are curable. It has been reported worldwide that persons with the...

journal_title：Journal of the American Academy of Dermatology

authors： Slade J,Marghoob AA,Salopek TG,Rigel DS,Kopf AW,Bart RS

更新日期：1995-03-01 00:00:00

abstract：:Hyperpigmentation of the skin is often refractory to conventional therapies, but has significant cosmetic implications if located on visible areas. Because laser systems are capable of removing pigment deposits caused by selective photothermolysis, we addressed the issue of whether the Q-switched ruby laser could be a...

journal_title：Journal of the American Academy of Dermatology

authors： Becker-Wegerich PM,Kuhn A,Malek L,Lehmann P,Megahed M,Ruzicka T

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:The optimal long-term dosing strategy for adalimumab (ADA) in hidradenitis suppurativa/acne inversa (HS) was evaluated by pooling the results of the PIONEER phase 3 trials and an open-label extension (OLE) study. OBJECTIVE:To assess the response to and tolerability of long-term administration of ADA in HS. ...

journal_title：Journal of the American Academy of Dermatology

authors： Zouboulis CC,Okun MM,Prens EP,Gniadecki R,Foley PA,Lynde C,Weisman J,Gu Y,Williams DA,Jemec GBE

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Despite a lack of evidence that dysplastic nevi are precursors to melanoma, a large proportion of dermatologists continue to treat them as such. Emerging data suggest that histologic grading approach may result in many unnecessary excisions. OBJECTIVE:Using a nongrading approach to diagnosis of Clark/dyspla...

journal_title：Journal of the American Academy of Dermatology

authors： Lozeau DF,Farber MJ,Lee JB

更新日期：2016-01-01 00:00:00

abstract：:Clinical and laboratory records of 100 biopsy-proved cases of generalized granuloma annulare seen at the Mayo Clinic between 1966 and 1986 were reviewed. The skin eruption involved predominantly annular lesions in 67 patients and predominantly nonannular papules in 33. The ratio of female-to-male patients was 2.9:1 in...

journal_title：Journal of the American Academy of Dermatology

authors： Dabski K,Winkelmann RK

更新日期：1989-01-01 00:00:00

abstract：BACKGROUND:The dysplastic melanocytic nevus (DMN) is a putative precursor for malignant melanoma in persons with a family history of melanoma and multiple large atypical moles. Furthermore, the concept that DMN confers increased risk for melanoma has been extended to those without a family history of melanoma. Some inv...

journal_title：Journal of the American Academy of Dermatology

authors： Roush GC,Dubin N,Barnhill RL

更新日期：1993-10-01 00:00:00

abstract：:Cicatricial pemphigoid is a chronic, presumed autoimmune, blistering disease of the mucous membranes and occasionally of the skin. The characteristic feature is scarring at the sites of healing. We report the use of thalidomide as a therapeutic agent to control previously resistant disease. ...

journal_title：Journal of the American Academy of Dermatology

authors： Duong DJ,Moxley RT 3rd,Kellman RM,Pincus SH,Gaspari AA

更新日期：2002-08-01 00:00:00

abstract：:A patient with fluoroscopy-induced subacute radiation dermatitis is described. Her biopsy specimen showed vacuolar change and necrotic keratinocytes with lymphocytes in direct apposition, or "satellitosis". Lymphocytes in the dermis and infiltrating the epidermis were predominantly CD8+ and a number of the lymphocytes...

journal_title：Journal of the American Academy of Dermatology

authors： Stone MS,Robson KJ,LeBoit PE

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Preventing fetal exposure to isotretinoin is an important public health goal. Since approval of isotretinoin (1982), the Food and Drug Administration has implemented several unsuccessful risk management programs aimed at preventing fetal exposure. The Kaiser Permanente isotretinoin risk management program in...

journal_title：Journal of the American Academy of Dermatology

authors： Cheetham TC,Wagner RA,Chiu G,Day JM,Yoshinaga MA,Wong L

更新日期：2006-09-01 00:00:00

abstract：BACKGROUND:Reports suggest that cigarette smoking might interfere with the effectiveness of antimalarial therapy as first-line treatment for cutaneous lupus erythematosus. Patients refractory to this treatment often must be treated with potentially more toxic regimens. OBJECTIVE:Our purpose was to examine the effects ...

journal_title：Journal of the American Academy of Dermatology

authors： Jewell ML,McCauliffe DP

更新日期：2000-06-01 00:00:00

abstract：:Tuberous sclerosis is characterized by epilepsy, mental retardation, and adenoma sebaceum. Computerized axial tomography (CAT) is a noninvasive laboratory test that can assist in the diagnosis of this syndrome radiologically. A positive CAT scan is often present before the calcifications are noted on skull x-rays and ...

journal_title：Journal of the American Academy of Dermatology

authors： Burkhart CG,El-Shaar A

更新日期：1981-01-01 00:00:00

abstract：:Three patients who had cardiac surgery developed a transient, noninflammatory subepidermal bullous eruption on the legs after epsilon-aminocaproic acid infusion. Fibrin thrombi were demonstrated in papillary dermal vessels. The use of epsilon-aminocaproic acid as an antifibrinolytic agent may predispose patients to cu...

journal_title：Journal of the American Academy of Dermatology

authors： Brooke CP,Spiers EM,Omura EF

更新日期：1992-11-01 00:00:00

abstract：OBJECTIVE:We sought to assess the difference in lesion management between combined examination (naked-eye and dermoscopy) and conventional naked-eye examination in evaluations for melanoma; and to assess the impact on patient treatment of facilities for digital follow-up of diagnostically equivocal lesions. METHODS:We...

journal_title：Journal of the American Academy of Dermatology

authors： Carli P,de Giorgi V,Chiarugi A,Nardini P,Weinstock MA,Crocetti E,Stante M,Giannotti B

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND:Onychomycosis is a prevalent infection of the nail caused primarily by dermatophytes. Fluconazole is active in vitro against the most common pathogens, penetrates into the nail bed, and is clinically effective in the treatment of a wide variety of fungal infections. OBJECTIVE:The purpose of this study was t...

journal_title：Journal of the American Academy of Dermatology

authors： Drake L,Babel D,Stewart DM,Rich P,Ling MR,Breneman D,Scher RK,Martin AG,Pariser DM,Pariser RJ,Ellis CN,Kang S,Katz HI,McDonald CJ,Muglia J,Savin RC,Webster G,Elewski BE,Leyden JJ,Bucko AD,Tschen EH,Hanifin JM,

更新日期：1998-06-01 00:00:00

abstract：:Calcinosis cutis is the deposition of insoluble calcium salts in the skin and subcutaneous tissue. We report the case of a 28-year-old Caucasian woman with cystic fibrosis in whom strikingly symmetrical and reticulate calcinosis cutis developed on the lower extremities, which was noted on histology to spare the eccrin...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman JS,Fulghum Walters R,Woosley J,Fine JD

更新日期：2003-12-01 00:00:00

abstract：BACKGROUND:Epidermal necrolysis (EN) involving ≥10% of the body surface area (BSA) is often complicated by bacterial infections. OBJECTIVE:We sought to describe the epidemiology of bloodstream infections (BSIs) in EN involving a BSA ≥10% and the diagnostic performances of skin cultures for predicting the pathogen(s) i...

journal_title：Journal of the American Academy of Dermatology

authors： Lecadet A,Woerther PL,Hua C,Colin A,Gomart C,Decousser JW,Mekontso Dessap A,Wolkenstein P,Chosidow O,de Prost N,Ingen-Housz-Oro S

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Botulinum toxin type A (BTX-A) is widely used for facial esthetics but is incompletely studied. OBJECTIVE:This study was conducted to evaluate the efficacy and safety of BTX-A treatment of glabellar lines. METHODS:Patients with moderate to severe glabellar lines at maximum frown received intramuscular inje...

journal_title：Journal of the American Academy of Dermatology

authors： Carruthers JA,Lowe NJ,Menter MA,Gibson J,Nordquist M,Mordaunt J,Walker P,Eadie N,BOTOX Glabellar Lines I Study Group.

更新日期：2002-06-01 00:00:00

abstract：:Pityriasis rosea is an acute, self-healing exanthem characterized by oval erythematous-squamous lesions of the trunk and limbs, that usually spares face, scalp, palms, and soles. Constitutional symptoms, which have the character of true prodromes; clinical features, which resemble those of the known exanthems; and man...

journal_title：Journal of the American Academy of Dermatology

authors： Drago F,Broccolo F,Rebora A

更新日期：2009-08-01 00:00:00

abstract：BACKGROUND:Although etanercept is used as a continuous therapy for moderate to severe plaque psoriasis, intermittent use may be necessary in some instances. OBJECTIVE:In this randomized, open-label study, we evaluated the effectiveness and safety of continuous versus interrupted etanercept therapy. METHODS:All patien...

journal_title：Journal of the American Academy of Dermatology

authors： Moore A,Gordon KB,Kang S,Gottlieb A,Freundlich B,Xia HA,Stevens SR

更新日期：2007-04-01 00:00:00

abstract：:Graft-versus-host disease (GVHD) is a T cell-mediated disease seen most commonly after hematopoietic stem cell transplantation. Rarely, a GVHD-like disease can be seen in patients with malignant thymoma. We describe a 50-year-old man with malignant thymoma who developed skin, liver, and intestinal manifestations simil...

journal_title：Journal of the American Academy of Dermatology

authors： Wadhera A,Maverakis E,Mitsiades N,Lara PN,Fung MA,Lynch PJ

更新日期：2007-10-01 00:00:00

abstract：:Certain scalp hair shafts from 2 of 10 cases of pili annulati examined by scanning electron microscopy exhibited an unusual weathering pattern. The majority of affected hair shafts showed minor surface abnormalities at regular intervals (nodes) associated with the underlying spaces. However, in a few examples, there w...

journal_title：Journal of the American Academy of Dermatology

authors： Feldmann KA,Dawber RP,Pittelkow MR,Ferguson DJ

更新日期：2001-10-01 00:00:00

abstract：:Dialogues in Dermatology, a monthly audio program from the American Academy of Dermatology, contains discussions between dermatologists on timely dermatologic topics. Commentaries from the Dialogues Editor-in-Chief, Warren R. Heymann, MD, are provided after each discussion as a topic summary. These highlights are prov...

journal_title：Journal of the American Academy of Dermatology

authors： Heymann WR

更新日期：2004-07-01 00:00:00