Noninflammatory bullae associated with epsilon-aminocaproic acid infusion.

abstract：:Xeroderma pigmentosum is associated with severe actinic degeneration of the skin. Our patient with xeroderma pigmentosum showed increasing actinic damage in some areas covered by clothes. We therefore performed a complete evaluation of the patient's exposure to ultraviolet radiation. This included transmission measure...

journal_title：Journal of the American Academy of Dermatology

authors： Bech-Thomsen N,Wulf HC,Ullman S

更新日期：1991-02-01 00:00:00

abstract：:Sera from 34 patients with lepromatous leprosy were screened for the presence of autoantibodies by indirect immunofluorescence using two epithelial cell lines, PTK2 and HEp2, as substrates. Indirect immunofluorescence staining of both substrates with the serum of a patient with lepromatous leprosy revealed a cytoplasm...

journal_title：Journal of the American Academy of Dermatology

authors： Frey FL,Gottlieb AB,Levis WR

更新日期：1988-05-01 00:00:00

abstract：:Primary cutaneous CD30 (Ki-1)-positive, large cell lymphomas (LCLs) represent a recently recognized group of cutaneous T-cell lymphomas with a favorable prognosis. The characteristic features of this cutaneous lymphoma are reviewed, differences with primary noncutaneous CD30+ LCLs emphasized, and its relation with oth...

journal_title：Journal of the American Academy of Dermatology

authors： Willemze R,Beljaards RC

更新日期：1993-06-01 00:00:00

abstract：:Cutaneous extramedullary hemopoiesis (EMH) is a rare complication of chronic myeloproliferative and myelodysplastic disorders. Chronic idiopathic myelofibrosis (CIMF) is the most common underlying condition. To date, fewer than 30 cases have been reported in the literature and there has been significant confusion with...

journal_title：Journal of the American Academy of Dermatology

authors： Haniffa MA,Wilkins BS,Blasdale C,Simpson NB

更新日期：2006-08-01 00:00:00

abstract：:We report two cases in which dermatophytic infection developed almost entirely within a radiation field mimicking an acute radiation effect. Radiotherapists and dermatologists should be aware of this possibility and be able to differentiate it from radiation dermatitis. Topical antifungal agents are the recommended tr...

journal_title：Journal of the American Academy of Dermatology

authors： Rosen T,Dupuy J,Maor M,Altman A

更新日期：1988-12-01 00:00:00

abstract：:The effects of cyclosporine were studied in nine patients suffering from pemphigus vulgaris. Of four patients treated with cyclosporine alone, only one cleared. Of four corticosteroid-resistant pemphigus vulgaris patients, all improved after cyclosporine addition to corticosteroids. The last patient treated from the b...

journal_title：Journal of the American Academy of Dermatology

authors： Barthelemy H,Frappaz A,Cambazard F,Mauduit G,Rouchouse B,Kanitakis J,Souteyrand P,Claudy AL,Thivolet J

更新日期：1988-06-01 00:00:00

abstract：:The incidence of malignant melanoma is increasing faster than that of any other cancer. It is important to identify subsets of the population at high risk of its development so that they can be observed more closely to identify early melanomas when they are curable. It has been reported worldwide that persons with the...

journal_title：Journal of the American Academy of Dermatology

authors： Slade J,Marghoob AA,Salopek TG,Rigel DS,Kopf AW,Bart RS

更新日期：1995-03-01 00:00:00

abstract：:In vivo, topical minoxidil therapy is associated with changes in the follicular epithelium, tissue and blood lymphocyte populations, lymphocyte blastogenic response to mitogens, and perifollicular vasculature. Biopsy specimens taken from areas of terminal hair regrowth show a dose-dependent increase in hair follicle l...

journal_title：Journal of the American Academy of Dermatology

authors： Fiedler-Weiss VC

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:The appropriate classification of study designs is important for review and assessment of the relevant scientific literature as a basis for decision making; however, little is known about whether study designs have been appropriately reported in the dermatology literature. OBJECTIVE:We aimed to validate the...

journal_title：Journal of the American Academy of Dermatology

authors： Ohn J,Eun SJ,Kim DY,Park HS,Cho S,Yoon HS

更新日期：2018-08-01 00:00:00

abstract：:In this randomized, double-blind, phase III trial, patients with psoriasis received etanercept for 24 weeks or placebo for 12 weeks followed by etanercept for 12 weeks. At week 12, improvement in Dermatology Life Quality Index was 47% to 61% with etanercept compared with 11% with placebo (P < .0001). Etanercept rapidl...

journal_title：Journal of the American Academy of Dermatology

authors： Feldman SR,Kimball AB,Krueger GG,Woolley JM,Lalla D,Jahreis A

更新日期：2005-11-01 00:00:00

abstract：:We describe a patient with zygomycosis that resembled herpes zoster infection. The diagnosis was readily made with a potassium hydroxide preparation that revealed sparsely to non-septate hyphae. The patient responded to combination antifungal therapy with amphotericin B and fluconazole. The clinical response correlate...

journal_title：Journal of the American Academy of Dermatology

authors： Woods SG,Elewski BE

更新日期：1995-02-01 00:00:00

abstract：:Skin toxicities are the most common side effects associated with the epidermal growth factor receptor inhibitor erlotinib, occurring in most patients receiving the drug. Clinical trials evaluating erlotinib for the treatment of non-small cell lung cancer have reported a range of skin disorders, the most common being a...

journal_title：Journal of the American Academy of Dermatology

authors： Kiyohara Y,Yamazaki N,Kishi A

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:Keloids are a common lesion arising from sites of previous trauma and are a considerable source of morbidity because of continued growth of lesions, pruritus, and physical appearance. They consist of mesenchymal cells embedded in a stroma of disordered collagen matrix. Clinically, keloids are distinguished f...

journal_title：Journal of the American Academy of Dermatology

authors： Kim A,DiCarlo J,Cohen C,McCall C,Johnson D,McAlpine B,Quinn AG,McLaughlin ER,Arbiser JL

更新日期：2001-11-01 00:00:00

abstract：:Allergic contact dermatitis (ACD), a delayed hypersensitivity skin reaction to environmental allergens, has a prevalence that is similar in children and adults. However, diagnostic testing for ACD in pediatric populations accounts for less than one tenth of all patch tests. The relative infrequency of pediatric patch ...

journal_title：Journal of the American Academy of Dermatology

authors： Neale H,Garza-Mayers AC,Tam I,Yu J

更新日期：2021-02-01 00:00:00

abstract：:Primary cutaneous T-cell lymphomas are non-Hodgkin's lymphomas with varied clinical presentation and prognosis. The most common subtypes of cutaneous T-cell lymphomas are the epidermotropic variants mycosis fungoides and Sézary syndrome. Treatment of mycosis fungoides has encompassed a variety of modalities including ...

journal_title：Journal of the American Academy of Dermatology

authors： Querfeld C,Rosen ST,Guitart J,Rademaker A,Fung BB,Posten W,Kuzel TM

更新日期：2004-07-01 00:00:00

abstract：:This study was designed to investigate the relationship between alteration of skin surface pH and the development of skin irritation. Application of a phosphate/borate/acetate buffer adjusted to pH 4.0-10.5 in a standard chamber irritation test did not result in significant clinical irritation. This was true in spite ...

journal_title：Journal of the American Academy of Dermatology

authors： Murahata RI,Toton-Quinn R,Finkey MB

更新日期：1988-01-01 00:00:00

abstract：:The American Academy of Dermatology's national program of Melanoma/Skin Cancer Detection and Prevention, developed in response to the rising incidence of invasive melanoma in the United States, has annually produced extensive print, radio, and television coverage about performing skin self-examination (SSE). This stud...

journal_title：Journal of the American Academy of Dermatology

authors： Robinson JK,Rigel DS,Amonette RA

更新日期：1998-05-01 00:00:00

abstract：:Diabetic dermopathy (DD) is the most common cutaneous manifestation of diabetes mellitus. DD refers to atrophic, hyperpigmented macules characteristically located on the shins of patients with diabetes. They have an unfavorable association with the 3 most common microangiopathic complications of diabetes mellitus: neu...

journal_title：Journal of the American Academy of Dermatology

authors： Morgan AJ,Schwartz RA

更新日期：2008-03-01 00:00:00

abstract：BACKGROUND:Glomangiomas are benign tumors arising from neuromyoarterial cells surrounding cutaneous arteriovenous anastomoses that serve as temperature regulators. They exist as solitary or multiple types, occurring sporadically or in a familial pattern, the latter of which is rare. OBJECTIVE:We describe a 4-generatio...

journal_title：Journal of the American Academy of Dermatology

authors： Blume-Peytavi U,Adler YD,Geilen CC,Ahmad W,Christiano A,Goerdt S,Orfanos CE

更新日期：2000-04-01 00:00:00

abstract：:Our scientific knowledge of bullous pemphigoid (BP) has dramatically progressed in recent years. However, despite the availability of various therapeutic options for the treatment of inflammatory diseases, only a few multicenter controlled trials have helped to define effective therapies in BP. A major obstacle in sha...

journal_title：Journal of the American Academy of Dermatology

authors： Murrell DF,Daniel BS,Joly P,Borradori L,Amagai M,Hashimoto T,Caux F,Marinovic B,Sinha AA,Hertl M,Bernard P,Sirois D,Cianchini G,Fairley JA,Jonkman MF,Pandya AG,Rubenstein D,Zillikens D,Payne AS,Woodley D,Zambruno

更新日期：2012-03-01 00:00:00

abstract：:The retinoids have been investigated extensively as chemopreventive and therapeutic agents in a variety of neoplasms. They have been shown to inhibit the proliferation of transformed cell lines in vitro and transplanted tumors in vivo. In cultured murine melanoma cells, retinoids inhibit proliferation and induce diffe...

journal_title：Journal of the American Academy of Dermatology

authors： Meyskens FL Jr,Edwards L,Levine NS

更新日期：1986-10-01 00:00:00

abstract：:This review focuses on some of the most common classes of parenteral and inhalational sedating agents used during cutaneous surgery. Emphasis also is placed on potential adverse effects and their treatments. ...

journal_title：Journal of the American Academy of Dermatology

authors： Weber PJ,Weber M,Dzubow LM

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Electronic claims and medical record databases are increasingly used for observational studies of psoriasis. The purpose of this study was to assess the validity of psoriasis diagnostic codes in an electronic database. METHODS:This study was performed in a population-based setting in Olmsted County, Minneso...

journal_title：Journal of the American Academy of Dermatology

authors： Icen M,Crowson CS,McEvoy MT,Gabriel SE,Maradit Kremers H

更新日期：2008-12-01 00:00:00

abstract：:Clofazimine has been in clinical use for almost 40 years, but little is known of its mechanism of action. The primary indication for clofazimine is multibacillary leprosy, but it is useful in several infectious and noninfectious diseases, such as typical myocobacterial infections, rhinoscleroma, pyoderma gangrenosum, ...

journal_title：Journal of the American Academy of Dermatology

authors： Arbiser JL,Moschella SL

更新日期：1995-02-01 00:00:00

abstract：:The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is a rare disorder caused by mutations of the FOXP3 gene. The FOXP3 gene encodes a DNA-binding protein of the forkhead/winged-helix family and is the central controller of the development of CD4+CD25+ regulatory T cells. CD4+CD25+ regu...

journal_title：Journal of the American Academy of Dermatology

authors： McGinness JL,Bivens MM,Greer KE,Patterson JW,Saulsbury FT

更新日期：2006-07-01 00:00:00

abstract：:This article reviews the definition of outcomes research. It explores the reasons that outcomes research should be conducted by practicing physicians in both university and private practice settings. Methods for outcomes research with examples relevant to dermatologists are detailed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Faust HB

更新日期：1998-06-01 00:00:00

abstract：:Nodular primary localized cutaneous amyloidosis is an uncommon disorder for which there is no consistently satisfactory treatment. The amyloid fibrils are thought to have an immunoglobulin light chain derivation and systemic involvement must be excluded in all cases. We report a patient with a large scalp lesion of no...

journal_title：Journal of the American Academy of Dermatology

authors： Truhan AP,Garden JM,Roenigk HH Jr

更新日期：1986-06-01 00:00:00

abstract：:This study was conducted to further evaluate the safety and efficacy of 3% topical minoxidil in the treatment of extensive alopecia areata. Patients were assigned to one of two treatment regimens in a double-blind manner. One group applied 3% minoxidil to the scalp twice daily for 64 weeks; the other group applied pla...

journal_title：Journal of the American Academy of Dermatology

authors： Price VH

更新日期：1987-03-01 00:00:00

abstract：BACKGROUND:There are large discrepancies in reported mortality for bullous pemphigoid (BP). OBJECTIVE:We sought to determine the mortality of a large cohort of patients with BP and compare this with age-matched control subjects. METHODS:Data were collected on 223 patients with a new diagnosis of BP between 1998 and 2...

journal_title：Journal of the American Academy of Dermatology

authors： Parker SR,Dyson S,Brisman S,Pennie M,Swerlick RA,Khan R,Manos S,Korman BD,Xia Z,Korman NJ

更新日期：2008-10-01 00:00:00

abstract：:Epithelioid hemangioendothelioma is an uncommon malignant vascular tumor usually involving soft tissue and, in rare cases, the skin. Histologically and biologically it is considered to be a borderline neoplasm between an angiolymphoid hyperplasia with eosinophilia and an epithelioid angiosarcoma. Here we describe an 1...

journal_title：Journal of the American Academy of Dermatology

authors： Forschner A,Harms D,Metzler G,Sönnichsen K,Ulmer A,Rassner G,Fierlbeck G

更新日期：2003-07-01 00:00:00