Zosteriform zygomycosis.

abstract：:Immunopathology continues to be important in diagnostic dermatopathology. Immunopathology is an invaluable tool for assessing the tissue of origin or direction of differentiation of cells. In some cases this can result in a more precise diagnosis. This article reviews the role of immunopathology in determining the bio...

journal_title：Journal of the American Academy of Dermatology

authors： Wallace ML,Smoller BR

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Onychomycosis is a common nail infection, often resulting in nail plate damage and deformity. Topical lacquer treatments have negligible efficacy. Oral treatments, although more efficacious, are limited by drug interactions and potential hepatotoxicity. OBJECTIVE:We investigated the safety and efficacy of e...

journal_title：Journal of the American Academy of Dermatology

authors： Elewski BE,Rich P,Pollak R,Pariser DM,Watanabe S,Senda H,Ieda C,Smith K,Pillai R,Ramakrishna T,Olin JT

更新日期：2013-04-01 00:00:00

abstract：:Patients with dark skin can present with morphologic variants, subtle disease presentations, and disease manifestations requiring unique management and therapies. With African Americans, Asians, and Hispanic Americans becoming a significant portion of the population, dermatologists must be able to diagnose and manage ...

journal_title：Journal of the American Academy of Dermatology

authors： Ebede T,Papier A

更新日期：2006-10-01 00:00:00

abstract：:A screening program for antiviral drugs begun at Burroughs Wellcome in the 1960s resulted in the discovery of acyclovir in 1974. Preclinical investigation brought the drug to clinical trials in 1977 and the first form of the drug (topical) was available to physicians in 1982. Activity of acyclovir is greatest against ...

journal_title：Journal of the American Academy of Dermatology

authors： King DH

更新日期：1988-01-01 00:00:00

abstract：:We describe a 6-year-old boy with a granulomatous lesion on the upper aspect of his left arm. Fusarium solani infection was confirmed by biopsy studies and cultures. The biopsy specimen showed an unusually extensive dermal invasion with fungal hyphae. This is an uncommon clinical presentation for deep cutaneous infect...

journal_title：Journal of the American Academy of Dermatology

authors： Nakamura Y,Xu X,Saito Y,Tateishi T,Takahashi T,Kawachi Y,Otsuka F

更新日期：2007-05-01 00:00:00

abstract：:The increased use of isotretinoin therapy for severe cystic acne has posed new problems for dermatologic surgeons. There have been recent reports in the literature of unexpected "atypical" scarring after dermabrasion in patients who have previously taken isotretinoin. This scarring was considered atypical because it o...

journal_title：Journal of the American Academy of Dermatology

authors： Katz BE,Mac Farlane DF

更新日期：1994-05-01 00:00:00

abstract：:Most cutaneous squamous cell carcinomas (SCCs) of the trunk and extremities are small enough to be cured by simple surgical excision. Because the risk of metastasis of SCCs of the head and neck arising from mucosal surfaces is higher than the risk of metastasis of SCCs arising from cutaneous surfaces, it may be more a...

journal_title：Journal of the American Academy of Dermatology

authors： Geohas J,Roholt NS,Robinson JK

更新日期：1994-04-01 00:00:00

abstract：BACKGROUND:The difficulties in accurately assessing pigmented skin lesions are ever present in practice. The recently described ABCD rule of dermatoscopy (skin surface microscopy at x10 magnification), based on the criteria asymmetry (A), border (B), color (C), and differential structure (D), improved diagnostic accura...

journal_title：Journal of the American Academy of Dermatology

authors： Nachbar F,Stolz W,Merkle T,Cognetta AB,Vogt T,Landthaler M,Bilek P,Braun-Falco O,Plewig G

更新日期：1994-04-01 00:00:00

abstract：:The first reported case of phenytoin-induced generalized nodular cutaneous pseudolymphoma without symptoms of the phenytoin hypersensitivity syndrome is presented. Despite the malignant histologic appearance of the dermal infiltrate, T-cell receptor gene rearrangement studies did not demonstrate monoclonality. The cut...

journal_title：Journal of the American Academy of Dermatology

authors： Braddock SW,Harrington D,Vose J

更新日期：1992-08-01 00:00:00

abstract：:Two patients with a hypersensitivity vasculitis in association with propylthiouracil (PTU) administration are described. Although both patients presented with a cutaneous eruption, our first patient suffered severe systemic manifestations and the second patient's involvement was primarily limited to the skin. Patients...

journal_title：Journal of the American Academy of Dermatology

authors： Chastain MA,Russo GG,Boh EE,Chastain JB,Falabella A,Millikan LE

更新日期：1999-11-01 00:00:00

abstract：:Cannabis arteritis is a serious peripheral vascular disease affecting young adults consuming cannabis. An increasing number of cases have been recently reported in Europe. The risk of amputation is high. Cannabis arteritis is often confused with atherosclerosis. We present a new case in which complete arterial revascu...

journal_title：Journal of the American Academy of Dermatology

authors： Noël B,Ruf I,Panizzon RG

更新日期：2008-05-01 00:00:00

abstract：:A syndrome of congenital atrichia, palmoplantar hyperkeratosis, mental retardation, and early loss of teeth was observed in four siblings (three women and one man). The pedigree is suggestive of either an autosomal recessive mode of inheritance or the inheritance of a (small) chromosomal translocation. This combinatio...

journal_title：Journal of the American Academy of Dermatology

authors： Steijlen PM,Neumann HA,der Kinderen DJ,Smeets DF,van der Kerkhof PC,Happle R

更新日期：1994-05-01 00:00:00

abstract：:As a wider variety of organisms are being identified in superficial fungal infections, more accurate methods of identification may be required to determine fungal susceptibility. The sensitivity of available methods, such as the minimal inhibitory concentration test, is reviewed. The sensitivities of causative pathoge...

journal_title：Journal of the American Academy of Dermatology

authors： Meinhof W

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:A new anticancer therapy, electrochemotherapy (ECT), has been introduced that entails exposing cancerous tissues to short pulses of electricity during chemotherapy. This enhances cell membrane permeability and has been shown to have potent antitumor effects in vitro in animal models and in several clinical t...

journal_title：Journal of the American Academy of Dermatology

authors： Glass LF,Jaroszeski M,Gilbert R,Reintgen DS,Heller R

更新日期：1997-10-01 00:00:00

abstract：:Kapos's varicelliform eruption usually occurs in persons with active skin disease of various types; however, in atopic dermatitis the condition may occur when the underlying disease is inactive. Two cases of widespread herpes simplex infection associated with Darier's disease are reported. In both cases, infection occ...

journal_title：Journal of the American Academy of Dermatology

authors： Toole JW,Hofstader SL,Ramsay CA

更新日期：1979-10-01 00:00:00

abstract：:Cryosurgery is a commonly used modality for treatment of benign and malignant lesions in dermatology. Although cryosurgery has been used for treatment of actinic keratoses, to our knowledge there have been no published reports on actual cure rates. This article presents a cryosurgical technic for treatment of actinic ...

journal_title：Journal of the American Academy of Dermatology

authors： Lubritz RR,Smolewski SA

更新日期：1982-11-01 00:00:00

abstract：BACKGROUND:The current standard tool for diagnosing allergic contact dermatitis (ACD) in the United States is the T.R.U.E. test panels, which consist of 23 allergens. Previous studies have raised concern regarding the adequacy of these panels in fully assessing patients with possible ACD. OBJECTIVE:We sought to examin...

journal_title：Journal of the American Academy of Dermatology

authors： Saripalli YV,Achen F,Belsito DV

更新日期：2003-07-01 00:00:00

abstract：BACKGROUND:Scleredema adultorum (SA) is a rare connective tissue disorder for which no treatment has proven to be effective. OBJECTIVE:Our purpose was to determine the effect of bath-PUVA therapy on SA. METHODS:Three patients were treated. Clinical evaluation of skin induration and thickness as well as ultrasonograph...

journal_title：Journal of the American Academy of Dermatology

authors： Hager CM,Sobhi HA,Hunzelmann N,Wickenhauser C,Scharenberg R,Krieg T,Scharffetter-Kochanek K

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Recent studies have shown a higher prevalence of cardiovascular (CV) risk factors in patients with rosacea. However, it remains unknown whether rosacea represents an independent CV risk factor. OBJECTIVE:We evaluated the risk of myocardial infarction, stroke, CV death, major adverse CV events, and all-cause...

journal_title：Journal of the American Academy of Dermatology

authors： Egeberg A,Hansen PR,Gislason GH,Thyssen JP

更新日期：2016-08-01 00:00:00

abstract：BACKGROUND:Onychomycosis, a fungal infection of the nail bed, is responsible for up to 50% of nail disorders. Although several surveys have been conducted in different parts of the world, there have been no multicenter epidemiologic surveys of onychomycosis in North America. OBJECTIVE:A 12-center study was undertaken ...

journal_title：Journal of the American Academy of Dermatology

authors： Ghannoum MA,Hajjeh RA,Scher R,Konnikov N,Gupta AK,Summerbell R,Sullivan S,Daniel R,Krusinski P,Fleckman P,Rich P,Odom R,Aly R,Pariser D,Zaiac M,Rebell G,Lesher J,Gerlach B,Ponce-De-Leon GF,Ghannoum A,Warner J,Is

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Lymphomatoid papulosis (LyP) is a cyclic papulonodular eruption that is clinically benign and histologically malignant. Association with hematologic neoplasias has been reported in 5% to 20% of all cases. OBJECTIVE:We sought to review the clinical and histopathologic features of LyP in pediatric patients. ...

journal_title：Journal of the American Academy of Dermatology

authors： de Souza A,Camilleri MJ,Wada DA,Appert DL,Gibson LE,el-Azhary RA

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Isotretinoin is a very effective drug for treating severe recalcitrant nodular acne. A new micronized formulation of isotretinoin has been shown to be clinically equivalent to standard isotretinoin with improved bioavailability and minimal food effect. The safety profile of the micronized formulation has not...

journal_title：Journal of the American Academy of Dermatology

authors： Strauss JS,Leyden JJ,Lucky AW,Lookingbill DP,Drake LA,Hanifin JM,Lowe NJ,Jones TM,Stewart DM,Jarratt MT,Katz I,Pariser DM,Pariser RJ,Tschen E,Chalker DK,Rafal ES,Savin RP,Roth HL,Chang LK,Baginski DJ,Kempers S,M

更新日期：2001-08-01 00:00:00

abstract：:Molecular and cellular understanding of psoriasis pathogenesis has evolved considerably over the last 30 years beginning in the early 1980s when psoriasis was thought to be a skin disease driven by keratinocyte hyperproliferation. During the next 20 years, the role of the immune system and T-helper (Th) cells in psori...

journal_title：Journal of the American Academy of Dermatology

authors： Lynde CW,Poulin Y,Vender R,Bourcier M,Khalil S

更新日期：2014-07-01 00:00:00

abstract：BACKGROUND:Relatively few persons with obsessive-compulsive disorder (OCD) come to psychiatric clinics for treatment. Our hypothesis was that patients with a form of OCD that involves compulsive hand and body washing might initially seek treatment from a dermatologist. OBJECTIVE:Our purpose was to screen patients atte...

journal_title：Journal of the American Academy of Dermatology

authors： Hatch ML,Paradis C,Friedman S,Popkin M,Shalita AR

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Lentigo maligna (LM) is a relatively common tumor with increasing prevalence and substantial morbidity. A variety of treatment modalities are available, though margin-control surgery offers the highest cure rate. We were interested in comparing long-term outcomes of Mohs micrographic surgery (MMS) versus sta...

journal_title：Journal of the American Academy of Dermatology

authors： Walling HW,Scupham RK,Bean AK,Ceilley RI

更新日期：2007-10-01 00:00:00

abstract：:Isotretinoin is most effective for patients with acne who fail to respond to other forms of treatment; virtually all patients respond to isotretinoin, 0.5 to 1.0 mg/kg/day. As many as 61% of patients are cured after one course, but 39% require further isotretinoin (16%) or oral antibiotics (23%). The relapse rate can ...

journal_title：Journal of the American Academy of Dermatology

authors： Layton AM,Cunliffe WJ

更新日期：1992-12-01 00:00:00

abstract：:Direct-to-consumer teledermatology is radically changing the way some patients obtain dermatologic care. Many direct-to-consumer teledermatology services offer care to patients younger than 18 years, but policies and standards are nonuniform. For pediatric patients, direct-to-consumer teledermatology is a substantial ...

journal_title：Journal of the American Academy of Dermatology

authors： Fogel AL,Teng J,Sarin KY

更新日期：2016-11-01 00:00:00

abstract：:Punctate hyperkeratosis of the palms and soles is an uncommon autosomal dominant condition. We report a 65-year-old man with this condition and review the literature. With electron microscopy, we have examined both clinically affected and adjacent clinically unaffected palmar skin. The only ultrastructural differences...

journal_title：Journal of the American Academy of Dermatology

authors： Rubenstein DJ,Schwartz RA,Hansen RC,Payne CM

更新日期：1980-07-01 00:00:00

abstract：:A 2 1/2-year-old white girl with citrullinemia accompanied by neurologic symptoms presented with 2- to 3-week loss of scalp hair. Examination of the scalp revealed 90% of the hairs to be broken off, leaving a stubble of hairs less than 1 mm in length. Microscopically, plucked hairs demonstrated flattening, twisting th...

journal_title：Journal of the American Academy of Dermatology

authors： Patel HP,Unis ME

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND:The hazards of acute radiation exposure are well known. Bone marrow failure from total body gamma or neutron irradiation is the most clinically relevant aspect of acute radiation disease. With nonhomogeneous exposure, as is characteristic in accidents, other organ systems, such as the skin, may be more impor...

journal_title：Journal of the American Academy of Dermatology

authors： Peter RU,Braun-Falco O,Birioukov A,Hacker N,Kerscher M,Peterseim U,Ruzicka T,Konz B,Plewig G

更新日期：1994-05-01 00:00:00