Immunohistochemistry in diagnostic dermatopathology.

abstract：:The effect of drug concentrations of 2.5%, 5%, and 10% upon the transepidermal penetration of 14C-benzoyl peroxide in a lotion vehicle was assessed in excised human skin and in vivo in the rhesus monkey. In vitro, penetration of benzoyl peroxide was concentration-dependent, both as to rate and to amount, as measured b...

journal_title：Journal of the American Academy of Dermatology

authors： Yeung D,Nacht S,Bucks D,Maibach HI

更新日期：1983-12-01 00:00:00

abstract：:Langerhans cell histiocytosis (LCH) is regarded as a disorder of histiocytic cell proliferation of the Langerhans type, probably resulting from altered immunoregulation. Cutaneous involvement is frequent and often appears as a scaling papular eruption that resembles seborrheic dermatitis; when limited to the scalp, sc...

journal_title：Journal of the American Academy of Dermatology

authors： Pakula AS,Paller AS

更新日期：1993-08-01 00:00:00

abstract：:Angiosarcoma that develops in areas of chronic lymphedema is also called Stewart-Treves syndrome. It usually appears in areas of lymphedema several years after mastectomy for breast carcinoma. Only 10% of these angiosarcomas occur in areas of chronic lymphedema as a result of another cause. We present a patient with e...

journal_title：Journal of the American Academy of Dermatology

authors： Hallel-Halevy D,Yerushalmi J,Grunwald MH,Avinoach I,Halevy S

更新日期：1999-08-01 00:00:00

abstract：:Poison ivy, poison oak, and poison sumac are now classified in the genus Toxicodendron which is readily distinguished from Rhus. In the United States, there are two species of poison oak, Toxicodendron diversilobum (western poison oak) and Toxicodendron toxicarium (eastern poison oak). There are also two species of po...

journal_title：Journal of the American Academy of Dermatology

authors： Guin JD,Gillis WT,Beaman JH

更新日期：1981-01-01 00:00:00

abstract：:Lymphocyte function as expressed by T-lymphocyte subsets and natural killer cell activity was evaluated in a group of Israeli patients with classic Kaposi's sarcoma. T-cell subsets were examined in 28 patients, 14 with lesions limited to the lower extremities and 14 with diffuse cutaneous or systemic involvement. CD4 ...

journal_title：Journal of the American Academy of Dermatology

authors： Friedman-Birnbaum R,Weltfriend S,Pollack S

更新日期：1991-06-01 00:00:00

abstract：:An association between HLA-DR1 and the development of multiple basal cell carcinomas was detected in southern Australia. A reduction in HLA-DR4 was found in patients with basal cell carcinoma compared with a local control group. The relative risk for HLA-DR1 was 2.1, which was lower than that for persons in farther co...

journal_title：Journal of the American Academy of Dermatology

authors： Czarnecki D,Lewis A,Nicholson I,Tait B

更新日期：1991-04-01 00:00:00

abstract：:Recently, low-dose 5-fluorouracil/cisplatin induction concurrent with radiation (chemoradiation) has been reported to be effective for locally advanced squamous cell carcinoma of the otorhinolaryngologic and gynecologic regions. However, to date, this therapeutic option has not been evaluated for squamous cell carcino...

journal_title：Journal of the American Academy of Dermatology

authors： Fujisawa Y,Umebayashi Y,Ichikawa E,Kawachi Y,Otsuka F

更新日期：2006-11-01 00:00:00

abstract：BACKGROUND:Current treatments for vitiligo, a common pigmentary disorder affecting around 1% of the world's population, are largely unsatisfactory. OBJECTIVE:We sought to report a Cochrane review of all interventions for the treatment of vitiligo. METHODS:We systematically searched a range of databases for randomized...

journal_title：Journal of the American Academy of Dermatology

authors： Whitton ME,Ashcroft DM,González U

更新日期：2008-10-01 00:00:00

abstract：:Three young and middle-aged patients developed severe bullous eruption after receiving various penicillins. The clinical findings included high fever, prostration, widespread bullous eruption mainly on the head, face, and extremities, targetlike lesions on the palms and soles, and severe erosions in almost all the muc...

journal_title：Journal of the American Academy of Dermatology

authors： Alcalay J,David M,Ingber A,Hazaz B,Sandbank M

更新日期：1988-02-01 00:00:00

abstract：BACKGROUND:Recipients of organ transplant who are immunosuppressed are at greatly increased risk of nonmelanoma skin cancers compared with the general population, but their risk of appendageal tumors is unknown. OBJECTIVE:Our aim was to conduct a systematic examination of cutaneous appendageal tumors arising in recipi...

journal_title：Journal of the American Academy of Dermatology

authors： Harwood CA,McGregor JM,Swale VJ,Proby CM,Leigh IM,Newton R,Khorshid SM,Cerio R

更新日期：2003-03-01 00:00:00

abstract：BACKGROUND:The concept of contact allergy aggravating or inducing oral lichenoid mucositis diagnosed as oral lichen planus (OLP) is well recognized but somewhat controversial. OBJECTIVE:We sought to identify clinically relevant contact allergens that may be important in the management of patients with OLP. METHODS:We...

journal_title：Journal of the American Academy of Dermatology

authors： Yiannias JA,el-Azhary RA,Hand JH,Pakzad SY,Rogers RS 3rd

更新日期：2000-02-01 00:00:00

abstract：:In this article we focus on updates in select etiologies of retiform purpura. These causes of retiform purpura, in addition to bacterial or fungal sepsis, disseminated intravascular coagulation, purpura fulminans, and catastrophic antiphospholipid syndrome, are important diagnoses with potential for morbidity and mort...

journal_title：Journal of the American Academy of Dermatology

authors： Georgesen C,Fox LP,Harp J

更新日期：2020-04-01 00:00:00

abstract：:Skin toxicities are the most common side effects associated with the epidermal growth factor receptor inhibitor erlotinib, occurring in most patients receiving the drug. Clinical trials evaluating erlotinib for the treatment of non-small cell lung cancer have reported a range of skin disorders, the most common being a...

journal_title：Journal of the American Academy of Dermatology

authors： Kiyohara Y,Yamazaki N,Kishi A

更新日期：2013-09-01 00:00:00

abstract：:Infections with mycobacteria are of importance in the differential diagnosis of skin lesions in immunocompromised patients. We report the case of a human immunodeficency virus (HIV)-infected patient who presented with an annular plaque as cutaneous manifestation of Mycobacterium haemophilum. Improvement of the immunol...

journal_title：Journal of the American Academy of Dermatology

authors： Friedli A,Krischer J,Hirschel B,Saurat JH,Pechère M

更新日期：2000-11-01 00:00:00

abstract：:This case describes an unusual presentation of dermatomyositis in a patient with ovarian carcinoma. The eruption appeared as a venous stasislike dermatitis. The temporal sequence of onset after chemotherapy administration suggested a possible drug-induced process. However, in the context of underlying ovarian carcinom...

journal_title：Journal of the American Academy of Dermatology

authors： Seidler AM,Wasserman DI,González-Serva A,Konnikov N

更新日期：2008-09-01 00:00:00

abstract：:In this randomized, double-blind, phase III trial, patients with psoriasis received etanercept for 24 weeks or placebo for 12 weeks followed by etanercept for 12 weeks. At week 12, improvement in Dermatology Life Quality Index was 47% to 61% with etanercept compared with 11% with placebo (P < .0001). Etanercept rapidl...

journal_title：Journal of the American Academy of Dermatology

authors： Feldman SR,Kimball AB,Krueger GG,Woolley JM,Lalla D,Jahreis A

更新日期：2005-11-01 00:00:00

abstract：:Papulosquamous diseases are a heterogeneous group of disorders whose etiology primarily is unknown. The nosology of these disorders is based on a descriptive morphology of clinical lesions characterized by scaly papules and plaques. The major entities in this group include psoriasis, parapsoriasis (including pityriasi...

journal_title：Journal of the American Academy of Dermatology

authors： Fox BJ,Odom RB

更新日期：1985-04-01 00:00:00

abstract：BACKGROUND:Nephrogenic systemic fibrosis is a fibrosing disorder associated with gadolinium (Gd)-based contrast agents dosed during renal insufficiency. OBJECTIVE:In two patients, Gd deposition in tissue affected by nephrogenic systemic fibrosis was quantified using inductively coupled plasma mass spectrometry. The pr...

journal_title：Journal of the American Academy of Dermatology

authors： High WA,Ranville JF,Brown M,Punshon T,Lanzirotti A,Jackson BP

更新日期：2010-01-01 00:00:00

abstract：:We present the case of an American adult patient with eosinophilic pustular folliculitis. The majority of previously reported patients have been Japanese. Eosinophilic pustular folliculitis is a rare condition characterized by recurrent, peripherally expanding, sterile papulopustules and plaques. Hair-bearing areas su...

journal_title：Journal of the American Academy of Dermatology

authors： Jaliman HD,Phelps RG,Fleischmajer R

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Comparing effectiveness of biologics in real-world settings will help inform treatment decisions. OBJECTIVES:We sought to compare therapeutic responses among patients initiating infliximab, adalimumab, or etanercept versus ustekinumab during the Psoriasis Longitudinal Assessment and Registry (PSOLAR). METH...

journal_title：Journal of the American Academy of Dermatology

authors： Strober BE,Bissonnette R,Fiorentino D,Kimball AB,Naldi L,Shear NH,Goyal K,Fakharzadeh S,Calabro S,Langholff W,You Y,Galindo C,Lee S,Lebwohl MG

更新日期：2016-05-01 00:00:00

abstract：BACKGROUND:Despite a high incidence of xeroderma pigmentosum, there is no previous publication from Libya. OBJECTIVE:The purpose was to study the clinical profile of Libyan cases of xeroderma pigmentosum. METHODS:With the help of a special protocol, 24 cases of xeroderma pigmentosum treated between 1981 and 1990 were...

journal_title：Journal of the American Academy of Dermatology

authors： Khatri ML,Shafi M,Mashina A

更新日期：1992-01-01 00:00:00

abstract：BACKGROUND:The vulvovaginal gingival syndrome is an uncommon and severe variant of lichen planus characterized by erosions or desquamation of vulval, vaginal, and gingival mucosae with a predilection for scarring and stricture formation. OBJECTIVE:We sought to define the clinical, immunopathologic, and human leukocyte...

journal_title：Journal of the American Academy of Dermatology

authors： Setterfield JF,Neill S,Shirlaw PJ,Theron J,Vaughan R,Escudier M,Challacombe SJ,Black MM

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:There are significant clinicopathological, genetic, and biological differences between acral lentiginous melanoma (ALM) and other types of melanoma. OBJECTIVE:We sought to investigate the use of sentinel lymph node (SLN) biopsy for patients with ALM. METHODS:This was a retrospective review of 116 patients ...

journal_title：Journal of the American Academy of Dermatology

authors： Ito T,Wada M,Nagae K,Nakano-Nakamura M,Nakahara T,Hagihara A,Furue M,Uchi H

更新日期：2015-01-01 00:00:00

abstract：:Livedo reticularis (LR) is a well-known, relatively common physical finding consisting of macular, violaceous, connecting rings that form a netlike pattern (Fig 1). In most cases, it is a completely benign finding related to cold exposure. However, there are many potential causes (Table I), and this can make the evalu...

journal_title：Journal of the American Academy of Dermatology

authors： Gibbs MB,English JC 3rd,Zirwas MJ

更新日期：2005-06-01 00:00:00

abstract：:Polymorphous sweat gland carcinoma is an unusual, recently described variant of low-grade malignant adnexal neoplasm of the skin characterized by a prolonged clinical course and predilection for the extremities. We describe a case of recurrent polymorphous sweat gland carcinoma in a 56-year-old man who presented with ...

journal_title：Journal of the American Academy of Dermatology

authors： Ronnen M,Ben-Dor D,Huszar M

更新日期：2002-06-01 00:00:00

abstract：:Global temperatures continue to rise, reaching new records almost every year this decade. Although the causes are debated, climate change is a reality. Consequences of climate change include melting of the arctic ice cap, rising of sea levels, changes in precipitation patterns, and increased severe weather events. Thi...

journal_title：Journal of the American Academy of Dermatology

authors： Kaffenberger BH,Shetlar D,Norton SA,Rosenbach M

更新日期：2017-01-01 00:00:00

abstract：:We report a male infant with Down syndrome who had a transient myeloproliferative disorder associated with skin lesions. He was transferred to a neonatal intensive care unit because of low body weight, fetal edema, disseminated intravascular coagulation, and 10% blast cells in the peripheral blood. On postnatal day (P...

journal_title：Journal of the American Academy of Dermatology

authors： Uhara H,Shiohara M,Baba A,Shiohara J,Saida T

更新日期：2009-05-01 00:00:00

abstract：:A new, quantitative modification of the vasoconstrictor assay was used to measure bioavailability of generic topical corticosteroid products in two categories: betamethasone valerate 0.1% cream and triamcinolone 0.1% cream. Betamethasone valerate products could be separated into two distinct categories, and triamcinol...

journal_title：Journal of the American Academy of Dermatology

authors： Jackson DB,Thompson C,McCormack JR,Guin JD

更新日期：1989-05-01 00:00:00

abstract：BACKGROUND:Acral vascular syndromes associated with malignancy have rarely been reported. OBJECTIVE:Our purpose was to assess the clinical and evolving features of paraneoplastic acral vascular syndromes. PATIENTS AND METHODS:Two cases of paraneoplastic gangrene are described and analyzed together with previously rep...

journal_title：Journal of the American Academy of Dermatology

authors： Poszepczynska-Guigné E,Viguier M,Chosidow O,Orcel B,Emmerich J,Dubertret L

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND:Pemphigus vulgaris (PV) shows autoimmune reaction against desmoglein 3 (Dsg3), whereas paraneoplastic pemphigus (PNP) shows autoimmune reaction against Dsg3 as well as numerous members of the plakin family. It has been demonstrated that in PV, dominant epitopes reside in N-terminal adhesive regions of Dsg3 a...

journal_title：Journal of the American Academy of Dermatology

authors： Futei Y,Amagai M,Hashimoto T,Nishikawa T

更新日期：2003-12-01 00:00:00