Livedo reticularis: an update.

abstract：:Pigmentary demarcation lines are borders of abrupt transition between more deeply pigmented skin and that of lighter pigmentation. Two patients developed these lines on the lower extremities during pregnancy. ...

journal_title：Journal of the American Academy of Dermatology

authors： James WD,Meltzer MS,Guill MA,Berger TG,Rodman OG

更新日期：1984-09-01 00:00:00

abstract：:In autosomal dominant skin disorders, a pronounced mosaic involvement may sometimes be found to be superimposed on the ordinary nonsegmental lesions. Such "type 2 segmental manifestation" reflects loss of heterozygosity occurring at an early developmental stage, giving rise to a cell clone that lacks the corresponding...

journal_title：Journal of the American Academy of Dermatology

authors： Happle R

更新日期：2010-01-01 00:00:00

abstract：:Kyrle's disease is a chronic, genetically determined, hyperkeratotic disorder occurring in the middle forties. We report fourteen cases of this disorder in a population of 1.5 million over a period of 15 years. We observed a female/male ratio of 6:1. Straw-colored keratotic plugs and flat scale show a marked predispos...

journal_title：Journal of the American Academy of Dermatology

authors： Cunningham SR,Walsh M,Matthews R,Fulton R,Burrows D

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Despite the prevalence of androgenetic alopecia among men, little is known about its psychological effects. OBJECTIVE:This investigation examined the psychosocial sequelae that balding men attribute to hair loss and compared balding and nonbalding men in personality functioning. METHODS:Subjects included 6...

journal_title：Journal of the American Academy of Dermatology

authors： Cash TF

更新日期：1992-06-01 00:00:00

abstract：:Pathologic T-cell activation is implicated in psoriasis progression. CD80, a costimulatory molecule involved in T-cell activation, likely plays a key role. IDEC-114, an IgG(1) anti-CD80 antibody, was evaluated for safety, pharmacokinetics, and preliminary clinical activity in this open-label, single-dose, dose-escalat...

journal_title：Journal of the American Academy of Dermatology

authors： Gottlieb AB,Lebwohl M,Totoritis MC,Abdulghani AA,Shuey SR,Romano P,Chaudhari U,Allen RS,Lizambri RG

更新日期：2002-11-01 00:00:00

abstract：:We report a case of multiple ectodermal defects with the principal features of eyelid apocrine hydrocystomas , hypodontia, and hypotrichosis. To the best of our knowledge this is the second such report and presents histologic features that are unique in our experience. ...

journal_title：Journal of the American Academy of Dermatology

authors： Burket JM,Burket BJ,Burket DA

更新日期：1984-05-01 00:00:00

abstract：BACKGROUND:It was unclear whether an increased number of common nevi (moles) predicts melanoma death. OBJECTIVE:We prospectively examined the association between number of common nevi and risk of melanoma death. METHODS:Our study used data from the Nurses' Health Study (n = 77,288 women) and Health Professionals Foll...

journal_title：Journal of the American Academy of Dermatology

authors： Li WQ,Cho E,Weinstock MA,Li S,Stampfer MJ,Qureshi AA

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:Despite a high incidence of xeroderma pigmentosum, there is no previous publication from Libya. OBJECTIVE:The purpose was to study the clinical profile of Libyan cases of xeroderma pigmentosum. METHODS:With the help of a special protocol, 24 cases of xeroderma pigmentosum treated between 1981 and 1990 were...

journal_title：Journal of the American Academy of Dermatology

authors： Khatri ML,Shafi M,Mashina A

更新日期：1992-01-01 00:00:00

abstract：:We report two cases of congenital curvilinear palpable hyperpigmentation on the posterior aspect of bilateral legs in male infants. These lesions appeared shortly after birth and mimicked child abuse with looped cord or postinflammatory hyperpigmentation. Histopathologic features showed lentiginous melanocytic hyperpl...

journal_title：Journal of the American Academy of Dermatology

authors： Zhu YI,Fitzpatrick JE,Weston WL

更新日期：2005-08-01 00:00:00

abstract：:This study was designed to investigate the relationship between alteration of skin surface pH and the development of skin irritation. Application of a phosphate/borate/acetate buffer adjusted to pH 4.0-10.5 in a standard chamber irritation test did not result in significant clinical irritation. This was true in spite ...

journal_title：Journal of the American Academy of Dermatology

authors： Murahata RI,Toton-Quinn R,Finkey MB

更新日期：1988-01-01 00:00:00

abstract：:With the growth of dermatologic surgery the appropriate use of local anesthesia is becoming an important issue. Thoughtful use of local anesthesia can improve the patient's experience and facilitate the surgical procedure. In this review we discuss historical and pharmacologic aspects of local anesthetic agents. Empha...

journal_title：Journal of the American Academy of Dermatology

authors： Grekin RC,Auletta MJ

更新日期：1988-10-01 00:00:00

abstract：:Calciphylaxis is a rare phenomenon of cutaneous necrosis that typically occurs in association with renal failure and has a poor prognosis. We report 5 new cases of calciphylaxis that illustrate the important clinical and histopathologic features of the disease. All patients had end-stage renal failure at the time that...

journal_title：Journal of the American Academy of Dermatology

authors： Oh DH,Eulau D,Tokugawa DA,McGuire JS,Kohler S

更新日期：1999-06-01 00:00:00

abstract：BACKGROUND:T-cell receptor (TCR) clonality may help establish a diagnosis of mycosis fungoides (MF). Routine clonality analysis is performed by using a polymerase chain reaction TCR- gamma assay, yet with this method, 10% to 50% of T-cell lymphomas escape detection. TCR- beta gene rearrangement is an additional assay. ...

journal_title：Journal of the American Academy of Dermatology

authors： Schachter O,Tabibian-Keissar H,Debby A,Segal O,Baum S,Barzilai A

更新日期：2020-11-01 00:00:00

abstract：:A combination of topical and oral antifungals is widely used to treat onychomycosis, but treatment failure is common and oral drugs may cause toxicity and potential drug interactions. For this reason, new approaches and strategies should be considered. The following case shows that photodynamic therapy (PDT) may repre...

journal_title：Journal of the American Academy of Dermatology

authors： Piraccini BM,Rech G,Tosti A

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Concern has been raised about the potential long-term effects of propranolol treatment for infantile hemangioma (IH). OBJECTIVES:We sought to assess psychologic (social, emotional, behavioral, and executive) functioning in children treated with propranolol for IH. METHODS:Twenty-seven patients with IH (6.1...

journal_title：Journal of the American Academy of Dermatology

authors： Moyakine AV,Spillekom-van Koulil S,van der Vleuten CJM

更新日期：2017-07-01 00:00:00

abstract：BACKGROUND:In recent years there has been an increasing focus on human subject protection and on documentation of ethical review in published clinical research. The JAAD clearly states in its instructions to authors, which adhere to the guidelines set forth by the International Committee of Medical Journal Editors, "st...

journal_title：Journal of the American Academy of Dermatology

authors： Perkins AC,Choi JM,Kimball AB

更新日期：2007-02-01 00:00:00

abstract：:The evaluation of skin findings is critical in identifying many types of injury, whether self- inflicted or accidentally or intentionally inflicted. Specific causes of injury include homicide, abuse, neglect, assault, self-inflicted injury, suicide, torture, poisoning, and bioterrorism. Forensic findings in hair and n...

journal_title：Journal of the American Academy of Dermatology

authors： Reddy K,Lowenstein EJ

更新日期：2011-05-01 00:00:00

abstract：:There is no topical antiacne medication that acts against all four of the major pathophysiologic features of acne: hyperkeratinization, sebum production, bacterial proliferation, and inflammation. Topical azelaic acid cream helps both to normalize keratinization and to reduce the proliferation of Propionibacterium acn...

journal_title：Journal of the American Academy of Dermatology

authors： Webster G

更新日期：2000-08-01 00:00:00

abstract：BACKGROUND:Highly variable results of topical diphenylcyclopropenone (DPCP) in the treatment of alopecia areata have been reported so far. OBJECTIVE:The purposes of our study were to evaluate the efficacy and tolerability of DPCP in the treatment of chronic, extensive alopecia areata and to assess the long-term overal...

journal_title：Journal of the American Academy of Dermatology

authors： Cotellessa C,Peris K,Caracciolo E,Mordenti C,Chimenti S

更新日期：2001-01-01 00:00:00

abstract：:A patient with symptomatic urticaria pigmentosa who responded to nifedipine therapy is reported. Relief from cold-induced urtication and flushing was obtained with 10 mg taken orally three times daily. Calcium influx is an early step in the degranulation of mast cells. We hypothesize that the beneficial effect of nife...

journal_title：Journal of the American Academy of Dermatology

authors： Fairley JA,Pentland AP,Voorhees JJ

更新日期：1984-10-01 00:00:00

abstract：:A 2 1/2-year-old white girl with citrullinemia accompanied by neurologic symptoms presented with 2- to 3-week loss of scalp hair. Examination of the scalp revealed 90% of the hairs to be broken off, leaving a stubble of hairs less than 1 mm in length. Microscopically, plucked hairs demonstrated flattening, twisting th...

journal_title：Journal of the American Academy of Dermatology

authors： Patel HP,Unis ME

更新日期：1985-01-01 00:00:00

abstract：:A group of 420 neonates underwent total cutaneous and oral mucosal examinations during the first week of life. Skin lesions were seen in almost every baby (99.3%). The eight most common dermatoses were desquamation (65.0%), Epstein's pearls (56.0%), sebaceous hyperplasia (48.0%), milia (36%), toxic erythema (34.8%), s...

journal_title：Journal of the American Academy of Dermatology

authors： Rivers JK,Frederiksen PC,Dibdin C

更新日期：1990-07-01 00:00:00

abstract：:Infantile perineal protrusion, a relatively newly recognized condition, is underreported in both the dermatologic and pediatric literature. The name "infantile perineal protrusion" has evolved based on the typical anatomic location, morphologic features, and prevalence in prepubertal children. It occurs in 3 settings:...

journal_title：Journal of the American Academy of Dermatology

authors： Khachemoune A,Guldbakke KK,Ehrsam E

更新日期：2006-06-01 00:00:00

abstract：:We report a case of a patient with scleromyxedema limited to the skin with an associated IgG lambda monoclonal protein treated successfully with high-dose dexamethasone. We encourage the continued investigation of this complex relationship between the clinical presentation of scleromyxedema and its frequently associat...

journal_title：Journal of the American Academy of Dermatology

authors： Horn KB,Horn MA,Swan J,Singhal S,Guitart J

更新日期：2004-08-01 00:00:00

abstract：BACKGROUND:Recurrences after Mohs micrographic surgery (MMS) have been associated in the past with aggressive tumor type, large tumor size, and location within certain anatomic subunits. These factors are beyond the control of the treating physician and not subject to quality improvement efforts. OBJECTIVE:We sought t...

journal_title：Journal of the American Academy of Dermatology

authors： Campbell T,Armstrong AW,Schupp CW,Barr K,Eisen DB

更新日期：2013-07-01 00:00:00

abstract：:Mutations in the cathepsin C gene have recently been detected in Papillon-Lefèvre syndrome (PLS). Until now, 5 cases with the late-onset variation of this disease have been reported in the literature. The genetic background of this type of PLS is still unknown. We describe a 46-year-old woman with late-onset transgred...

journal_title：Journal of the American Academy of Dermatology

authors： Pilger U,Hennies HC,Truschnegg A,Aberer E

更新日期：2003-11-01 00:00:00

abstract：:To determine whether systemic hydrocortisone can elicit allergic skin reactions in patients with contact hypersensitivity to hydrocortisone, we studied four patients with contact hypersensitivity to hydrocortisone and hydrocortisone-17-butyrate and two patients with contact hypersensitivity to hydrocortisone-17-butyra...

journal_title：Journal of the American Academy of Dermatology

authors： Lauerma AI,Reitamo S,Maibach HI

更新日期：1991-02-01 00:00:00

abstract：BACKGROUND:Dermatopathologists often are asked by clinicians to report margins on punch excisions of melanocytic lesions. OBJECTIVE:We sought to determine the adequacy of surgical margins on melanocytic lesions submitted with intention of complete excision using punch removal technique. METHODS:We conducted prospecti...

journal_title：Journal of the American Academy of Dermatology

authors： Chang TT,Somach SC,Wagamon K,Somani AK,Pomeranz J,Jaworsky C,Bass J,Winfield HL,Sigel JE,Rosenberg AS

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:It is unclear whether patients with atopic dermatitis (AD) have an altered prevalence or risk for contact sensitization. Increased exposure to chemicals in topical products together with impaired skin barrier function suggest a higher risk, whereas the immune profile suggests a lower risk. OBJECTIVE:To perf...

journal_title：Journal of the American Academy of Dermatology

authors： Hamann CR,Hamann D,Egeberg A,Johansen JD,Silverberg J,Thyssen JP

更新日期：2017-07-01 00:00:00

abstract：:When treating psoriasis, various topical emollients exist that can affect the penetration of ultraviolet radiation in phototherapy. Compared with normal-appearing skin with a reflectance of 4% to 5%, psoriatic skin has higher reflectance as a result of its increased air-to-corneocyte interfaces. Studies have tested th...

journal_title：Journal of the American Academy of Dermatology

authors： Asztalos ML,Heller MM,Lee ES,Koo J

更新日期：2013-05-01 00:00:00