Combination azelaic acid therapy for acne vulgaris.

Abstract:

:There is no topical antiacne medication that acts against all four of the major pathophysiologic features of acne: hyperkeratinization, sebum production, bacterial proliferation, and inflammation. Topical azelaic acid cream helps both to normalize keratinization and to reduce the proliferation of Propionibacterium acnes, and has proven to be effective against both noninflammatory and inflammatory lesions. The results of a recent study now demonstrate that its efficacy can be enhanced, and patient ratings of overall impression improved, when it is used in combination with other topical medications such as benzoyl peroxide 4% gel, clindamycin 1% gel, tretinoin 0.025% cream, and erythromycin 3%/benzoyl peroxide 5% gel. Furthermore, another study has shown that azelaic acid plus benzoyl peroxide achieves greater efficacy and higher patient ratings of convenience than monotherapy with erythromycin-benzoyl peroxide gel.

journal_name

J Am Acad Dermatol

authors

Webster G

doi

10.1067/mjd.2000.108318

subject

Has Abstract

pub_date

2000-08-01 00:00:00

pages

S47-50

issue

2 Pt 3

eissn

0190-9622

issn

1097-6787

pii

S0190-9622(00)37259-0

journal_volume

43

pub_type

杂志文章,评审
  • Chemoradiation using low-dose cisplatin and 5-fluorouracil in locally advanced squamous cell carcinoma of the skin: a report of two cases.

    abstract::Recently, low-dose 5-fluorouracil/cisplatin induction concurrent with radiation (chemoradiation) has been reported to be effective for locally advanced squamous cell carcinoma of the otorhinolaryngologic and gynecologic regions. However, to date, this therapeutic option has not been evaluated for squamous cell carcino...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2005.12.035

    authors: Fujisawa Y,Umebayashi Y,Ichikawa E,Kawachi Y,Otsuka F

    更新日期:2006-11-01 00:00:00

  • The contact urticaria syndrome--an updated review.

    abstract::The term "the contact urticaria syndrome," proposed in 1975, has been generally accepted and led to proliferation of new examples. This paper summarizes this clinical material and presents a diagnostic and pathogenetic evaluation method. The risks (and minimization, thereof) of systemic skin test-induced reactions are...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/s0190-9622(81)70099-9

    authors: von Krogh G,Maibach HI

    更新日期:1981-09-01 00:00:00

  • Inflammatory bowel disease is associated with hidradenitis suppurativa: Results from a multicenter cross-sectional study.

    abstract:BACKGROUND:Hidradenitis suppurativa (HS) is often associated with inflammatory bowel disease (IBD; Crohn's disease or ulcerative colitis). However, the prevalence of IBD in HS patients is unknown. OBJECTIVE:To determine the prevalence of IBD in HS patients, and determine if patients with HS and IBD have a distinct HS ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,多中心研究

    doi:10.1016/j.jaad.2016.08.031

    authors: Deckers IE,Benhadou F,Koldijk MJ,Del Marmol V,Horváth B,Boer J,van der Zee HH,Prens EP

    更新日期:2017-01-01 00:00:00

  • The flushing patient: differential diagnosis, workup, and treatment.

    abstract:UNLABELLED:Cutaneous flushing-a common presenting complaint to dermatologists, allergists, internists, and family practitioners-results from changes in cutaneous blood flow triggered by multiple conditions. Most cases are caused by very common, benign diseases, such as rosacea or climacterum, that are readily apparent ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2005.07.057

    authors: Izikson L,English JC 3rd,Zirwas MJ

    更新日期:2006-08-01 00:00:00

  • Sclerotic fibromas of the skin.

    abstract::Eleven cases of a peculiar, hyalinized, hypocellular dermal fibroma are reported. The lesions are characterized by epidermal atrophy, a whorled appearance of sclerotic collagen bundles separated by clefts containing mucin, and sharp demarcation of the lesions from the surrounding normal skin. They are small white or f...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(89)70033-5

    authors: Rapini RP,Golitz LE

    更新日期:1989-02-01 00:00:00

  • Isotretinoin improves the appearance of photodamaged skin: results of a 36-week, multicenter, double-blind, placebo-controlled trial.

    abstract::Photodamaged skin occurs as a result of long-term exposure to ultraviolet radiation. The incidence of photodamage in European and North American populations with Fitzpatrick skin types I, II, and III is estimated at 80% to 90%. We conducted a double-blind clinical trial to test the efficacy and safety of 0.1% isotreti...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0190-9622(00)90009-4

    authors: Maddin S,Lauharanta J,Agache P,Burrows L,Zultak M,Bulger L

    更新日期:2000-01-01 00:00:00

  • WITHDRAWN: JAAD Game Changers: Multivariate analysis of potential risk factors for lymph node metastasis in patients with cutaneous squamous cell carcinoma of the head and neck.

    abstract::The Publisher regrets that this article is an accidental duplication of an article that has already been published in J Am Acad Dermatol, 80 (2019) 607 - 607, https://doi.org/10.1016/j.jaad.2018.10.049. The duplicate article has therefore been withdrawn. The full Elsevier Policy on Article Withdrawal can be found at h...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,撤回出版物

    doi:10.1016/j.jaad.2018.11.005

    authors: Lake E

    更新日期:2019-05-01 00:00:00

  • Indoleamine 2,3-dioxygenase-expressing myeloid dendritic cells and macrophages in infectious and noninfectious cutaneous granulomas.

    abstract:BACKGROUND:The enzyme indoleamine 2,3-dioxygenase (IDO) degrades the essential amino acid tryptophan, and this degradation is an immunosuppressive mechanism that is mainly used by antigen-presenting cells. IDO-expressing dendritic cells and macrophages have previously been identified as components of lymph node granulo...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2010.07.050

    authors: von Bubnoff D,Scheler M,Wilms H,Wenzel J,von Bubnoff N,Häcker G,Schultze J,Popov A,Racz P,Bieber T,Wickenhauser C

    更新日期:2011-10-01 00:00:00

  • The impact of emollients on phototherapy: a review.

    abstract::When treating psoriasis, various topical emollients exist that can affect the penetration of ultraviolet radiation in phototherapy. Compared with normal-appearing skin with a reflectance of 4% to 5%, psoriatic skin has higher reflectance as a result of its increased air-to-corneocyte interfaces. Studies have tested th...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jaad.2012.05.034

    authors: Asztalos ML,Heller MM,Lee ES,Koo J

    更新日期:2013-05-01 00:00:00

  • A phase 2, randomized dose-finding study of tapinarof (GSK2894512 cream) for the treatment of atopic dermatitis.

    abstract:BACKGROUND:Safe and efficacious topical treatments are needed for atopic dermatitis (AD). OBJECTIVE:We assessed the safety and efficacy of tapinarof cream (2 concentrations and 2 application frequencies) in patients with AD. METHODS:A double-blind, vehicle-controlled, randomized, 6-arm trial (1:1:1:1:1:1) in patients...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,随机对照试验

    doi:10.1016/j.jaad.2018.06.047

    authors: Peppers J,Paller AS,Maeda-Chubachi T,Wu S,Robbins K,Gallagher K,Kraus JE

    更新日期:2019-01-01 00:00:00

  • Acitretin improves psoriasis in a dose-dependent fashion.

    abstract::Acitretin, a metabolite of etretinate, was given to 38 patients for the treatment of psoriasis. During the first 8 weeks patients received either placebo, 10 mg, 25 mg, 50 mg, or 75 mg of acitretin daily in a double-blind manner. The dosages of 10 mg and 25 mg daily did not achieve any statistically significant improv...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 临床试验,杂志文章

    doi:10.1016/s0190-9622(88)70086-9

    authors: Goldfarb MT,Ellis CN,Gupta AK,Tincoff T,Hamilton TA,Voorhees JJ

    更新日期:1988-04-01 00:00:00

  • Annular atrophic lichen planus.

    abstract::We describe a case of generalized, asymptomatic, chronic annular lichen planus. The centers of the large annular lesions were atrophic and had lost their elasticity. Histologic examination revealed an absence of elastic fiber in the center. Electron microscopy revealed fragmented elastic fibers. Examination of early l...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(91)70212-k

    authors: Friedman DB,Hashimoto K

    更新日期:1991-08-01 00:00:00

  • Juvenile chronic granulocytic leukemia, juvenile xanthogranulomas, and neurofibromatosis. Case report and review of the literature.

    abstract::A 22-month-old boy had xanthomatous skin lesions, neurofibromatosis, and chronic granulocytic leukemia. Histologic examination of the xanthomatous skin lesions disclosed juvenile xanthogranulomas. Twenty-three previously published cases of this association are reviewed. ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章,评审

    doi:10.1016/0190-9622(90)70136-6

    authors: Morier P,Mérot Y,Paccaud D,Beck D,Frenk E

    更新日期:1990-05-01 00:00:00

  • Cheilitis glandularis: a clinical marker for both malignancy and/or severe inflammatory disease of the oral cavity.

    abstract::We report the case of an 84-year-old white male who underwent vermilionectomy for removal of a tumor, which proved to be squamous cell carcinoma. Chelitis glandularis related to marked actinic damage was noted at a subsequent visit. The presence of chelitis glandularis should be investigated for the presence of neopla...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2005.06.030

    authors: Carrington PR,Horn TD

    更新日期:2006-02-01 00:00:00

  • Hepatonecrosis resulting from parenteral gold therapy in pemphigus vulgaris.

    abstract::A patient who had pemphigus vulgaris received therapy with gold thiomalate in addition to dexamethasone. Three weeks after the initiation of parenteral gold the patient developed acute hepatitis. Causes other than gold toxicity were ruled out, and the patient recovered completely after discontinuation of gold therapy....

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(93)70019-p

    authors: Rye B,Krusinski PA

    更新日期:1993-01-01 00:00:00

  • Treatment of acquired perforating dermatosis with narrowband ultraviolet B.

    abstract::Acquired perforating dermatosis is difficult to treat. We describe effective therapy of acquired perforating dermatosis with narrowband UVB in 5 patients. Phototherapy was given 2 or 3 times weekly. The dose was started at 400 mJ/cm(2) and increased to a maximum of 1500 mJ/cm(2). All lesions disappeared completely aft...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2004.02.009

    authors: Ohe S,Danno K,Sasaki H,Isei T,Okamoto H,Horio T

    更新日期:2004-06-01 00:00:00

  • Kaposi varicelliform eruption in patients with Darier disease: a 20-year retrospective study.

    abstract:BACKGROUND:Kaposi varicelliform eruption (KVE), or herpes simplex virus (HSV) superinfection of pre-existing skin lesions, may complicate Darier disease. OBJECTIVE:We sought to compare the clinical features and outcomes of patients with Darier disease who developed KVE superinfection with those who did not. METHODS:A...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2014.12.001

    authors: Vogt KA,Lohse CM,El-Azhary RA,Gibson LE,Lehman JS

    更新日期:2015-03-01 00:00:00

  • Pigmentary demarcation lines: a population survey.

    abstract::An examination of 380 patients was accomplished in order to determine the frequency of occurrence of pigmentary demarcation lines in an unselected population. Both white and black patients were included in the study, and there was an equal sex distribution. Separation of data by age groups enabled us to determine that...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(87)70078-4

    authors: James WD,Carter JM,Rodman OG

    更新日期:1987-03-01 00:00:00

  • Trends in dermatology practices and the implications for the workforce.

    abstract:BACKGROUND:The American Academy of Dermatology (AAD) practice profile surveys have been conducted for more than a decade to gauge trends in our workforce supply and demand. OBJECTIVE:To update the trends and current workforce issues for the field of dermatology. METHODS:The AAD Practice Profile Survey is sent by both...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2017.06.030

    authors: Ehrlich A,Kostecki J,Olkaba H

    更新日期:2017-10-01 00:00:00

  • Once-weekly fluconazole (150, 300, or 450 mg) in the treatment of distal subungual onychomycosis of the fingernail.

    abstract:BACKGROUND:Onychomycosis is a prevalent infection of the nail caused primarily by dermatophytes. Fluconazole is active in vitro against the most common pathogens, penetrates into the nail bed, and is clinically effective in the treatment of a wide variety of fungal infections. OBJECTIVE:The purpose of this study was t...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 临床试验,杂志文章,多中心研究,随机对照试验

    doi:10.1016/s0190-9622(98)70491-8

    authors: Drake L,Babel D,Stewart DM,Rich P,Ling MR,Breneman D,Scher RK,Martin AG,Pariser DM,Pariser RJ,Ellis CN,Kang S,Katz HI,McDonald CJ,Muglia J,Savin RC,Webster G,Elewski BE,Leyden JJ,Bucko AD,Tschen EH,Hanifin JM,

    更新日期:1998-06-01 00:00:00

  • Cannabis arteritis.

    abstract::Cannabis arteritis is a serious peripheral vascular disease affecting young adults consuming cannabis. An increasing number of cases have been recently reported in Europe. The risk of amputation is high. Cannabis arteritis is often confused with atherosclerosis. We present a new case in which complete arterial revascu...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2007.04.024

    authors: Noël B,Ruf I,Panizzon RG

    更新日期:2008-05-01 00:00:00

  • Porokeratosis of Mibelli: benzylhydrochlorothiazide-induced new lesions accompanied by eosinophilic spongiosis.

    abstract::We observed the course of development of porokeratosis stimulated by benzylhydrochlorothiazide (BHCTh) in normal-appearing skin of a patient with long-standing stable porokeratosis of Mibelli. A 72-year-old Japanese man had had porokeratosis of Mibelli for more than 50 years. During administration of BHCTh for 1 year ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(84)70172-1

    authors: Inamoto N,Watanabe T,Nakamura K

    更新日期:1984-08-01 00:00:00

  • Lichen planus pemphigoides: identification of 180 kd hemidesmosome antigen.

    abstract::We describe a man with lichen planus pemphigoides. Direct immunofluorescence studies of peribullous skin showed linear deposition of IgG and C3 in the basement membrane zone. Indirect immunofluorescence studies disclosed circulating anti-basement membrane zone antibodies. Immunoelectron microscopy demonstrated binding...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(95)91554-0

    authors: Tamada Y,Yokochi K,Nitta Y,Ikeya T,Hara K,Owaribe K

    更新日期:1995-05-01 00:00:00

  • Histologic features of chronic cutaneous lupus erythematosus of the scalp using horizontal sectioning: Emphasis on follicular findings.

    abstract:BACKGROUND:Chronic cutaneous lupus erythematosus (CCLE) often affects the scalp resulting in scarring alopecia. While histopathologic findings of CCLE have been well described, there is little written on the morphologic changes to the hair follicles in this condition. OBJECTIVE:We aim to determine the histopathologic ...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2017.02.039

    authors: Chung HJ,Goldberg LJ

    更新日期:2017-08-01 00:00:00

  • Multiple vascular fibromas and myxoid fibromas of the fingers. A histologic and ultrastructural study.

    abstract::A father and his son were seen because of multiple wartlike lesions on their fingers and palms. On histologic examination, these lesions showed changes compatible with vascular fibromas, myxoid fibromas, and, in a few instances, verruca vulgaris. We are not aware of reports of similar cases in the dermatologic literat...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(80)80367-7

    authors: Coskey RJ,Mehregan AH,Lupulescu AP

    更新日期:1980-05-01 00:00:00

  • Prospective study of cosmetic reactions: 1977-1980. North American Contact Dermatitis Group.

    abstract::This prospective study (1977-1980) of cosmetic adverse reactions by eleven dermatologists identified 487 cases of cosmetic-induced dermatitis. Approximately half of the cases were covert in nature. Eight percent were due to allergic contact dermatitis; the face, eye, and upper arm were the most involved sites. Skin ca...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(82)70080-5

    authors: Eiermann HJ,Larsen W,Maibach HI,Taylor JS

    更新日期:1982-05-01 00:00:00

  • Flow cytometric DNA content analysis of a case of pilomatrix carcinoma showing multiple recurrences and invasion of the cranial vault.

    abstract::Pilomatrix carcinomas are rare neoplasms of the skin that may be locally aggressive or metastatic. The differentiation of these tumors from benign pilomatrixomas depends on a constellation of microscopic features, some of which may be equivocal or absent in individual biopsy specimens. We encountered a tumor with dist...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/0190-9622(90)70193-l

    authors: Rabkin MS,Wittwer CT,Soong VY

    更新日期:1990-07-01 00:00:00

  • Idiopathic familial onychomadesis.

    abstract::Onychomadesis is defined as spontaneous separation of the nail plate from the nail bed, beginning at its proximal end and resulting in the shedding of the nail. It has been associated with a variety of clinical settings, including systemic illnesses, generalized skin diseases, and drug therapies. There have been a sma...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1067/mjd.2000.101588

    authors: Mehra A,Murphy RJ,Wilson BB

    更新日期:2000-08-01 00:00:00

  • Follicular mucinosis: a detailed morphologic and immunopathologic study.

    abstract::Two patients with the benign type of follicular mucinosis (FM) are presented. Their clinical features and course were characteristic for this subgroup of FM. Light and electron microscopy, direct immunofluorescence, and immunoperoxidase cell marker studies were undertaken to characterize the nature of the disease proc...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/s0190-9622(84)70091-0

    authors: Lancer HA,Bronstein BR,Nakagawa H,Bhan AK,Mihm MC Jr

    更新日期:1984-05-01 00:00:00

  • Dark pigmented lesions: diagnostic accuracy of dermatoscopy and reflectance confocal microscopy in a tertiary referral center for skin cancer diagnosis.

    abstract:BACKGROUND:There is lack of studies on the diagnostic accuracy of dermatoscopy and reflectance confocal microscopy (RCM) for dark pigmented lesions. OBJECTIVE:To assess the diagnostic accuracy of dermatoscopy plus confocal microscopy for melanoma diagnosis of dark pigmented lesions in real life. METHODS:Prospective a...

    journal_title:Journal of the American Academy of Dermatology

    pub_type: 杂志文章

    doi:10.1016/j.jaad.2020.07.084

    authors: Longo C,Mazzeo M,Raucci M,Cornacchia L,Lai M,Bianchi L,Peris K,Pampena R,Pellacani G

    更新日期:2020-07-27 00:00:00