The impact of emollients on phototherapy: a review.

abstract：:Infections with mycobacteria are of importance in the differential diagnosis of skin lesions in immunocompromised patients. We report the case of a human immunodeficency virus (HIV)-infected patient who presented with an annular plaque as cutaneous manifestation of Mycobacterium haemophilum. Improvement of the immunol...

journal_title：Journal of the American Academy of Dermatology

authors： Friedli A,Krischer J,Hirschel B,Saurat JH,Pechère M

更新日期：2000-11-01 00:00:00

abstract：BACKGROUND:The hazards of acute radiation exposure are well known. Bone marrow failure from total body gamma or neutron irradiation is the most clinically relevant aspect of acute radiation disease. With nonhomogeneous exposure, as is characteristic in accidents, other organ systems, such as the skin, may be more impor...

journal_title：Journal of the American Academy of Dermatology

authors： Peter RU,Braun-Falco O,Birioukov A,Hacker N,Kerscher M,Peterseim U,Ruzicka T,Konz B,Plewig G

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Tissue-destructive and more selective cytotoxic therapies are the main methods used to treat actinic cheilitis. A topical immune stimulant, 5% imiquimod cream, has recently been used for treatment of cutaneous epithelial malignancies including squamous cell carcinoma in situ and basal cell carcinoma. OBJECT...

journal_title：Journal of the American Academy of Dermatology

authors： Smith KJ,Germain M,Yeager J,Skelton H

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Few studies have examined patients initially presenting with clinical features of urticarial dermatitis (UD). OBJECTIVE:We sought to examine clinical and laboratory evaluations and final diagnoses of patients with clinical features of UD. METHODS:This was a retrospective review of patients with UD seen at ...

journal_title：Journal of the American Academy of Dermatology

authors： Hannon GR,Wetter DA,Gibson LE

更新日期：2014-02-01 00:00:00

abstract：BACKGROUND:Patients with rosacea have increased amounts of cathelicidin and protease activity but their usefulness as disease biomarkers is unclear. OBJECTIVE:We sought to evaluate the effect of doxycycline treatment on cathelicidin expression, protease activity, and clinical response in rosacea. METHODS:In all, 170 ...

journal_title：Journal of the American Academy of Dermatology

authors： Di Nardo A,Holmes AD,Muto Y,Huang EY,Preston N,Winkelman WJ,Gallo RL

更新日期：2016-06-01 00:00:00

abstract：:A concept of dichotomous types of segmental involvement of autosomal dominant skin disorders has recently been proposed. Among the different types of porokeratosis, disseminated superficial actinic porokeratosis is known to be an autosomal dominant skin disorder, and linear porokeratosis represents the segmental form ...

journal_title：Journal of the American Academy of Dermatology

authors： Freyschmidt-Paul P,Hoffmann R,König A,Happle R

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Chronic cutaneous lupus erythematosus (CCLE) often affects the scalp resulting in scarring alopecia. While histopathologic findings of CCLE have been well described, there is little written on the morphologic changes to the hair follicles in this condition. OBJECTIVE:We aim to determine the histopathologic ...

journal_title：Journal of the American Academy of Dermatology

authors： Chung HJ,Goldberg LJ

更新日期：2017-08-01 00:00:00

abstract：:Since proteolytic processes are prominent in psoriasis, sera of forty-five psoriatics were examined for alpha 1-antitrypsin (alpha 1-AT) phenotype and eighteen sera, for alpha 1-AT content and function. Five sera (11.1%) had heterozygous phenotypes (2 MZ and 3 MS), a prevalence of Z and S variants similar to that repo...

journal_title：Journal of the American Academy of Dermatology

authors： Lipkin G,Galdston M,Kueppers F

更新日期：1984-10-01 00:00:00

abstract：BACKGROUND:Drug-specific T cells are involved in the pathogenesis of cutaneous adverse drug reactions (CADRs). OBJECTIVE:We sought to evaluate the diagnostic role of in vitro drug-induced release of interferon gamma in CADRs. METHODS:The study group consisted of 36 patients with CADRs after intake of 106 drugs that w...

journal_title：Journal of the American Academy of Dermatology

authors： Halevy S,Cohen AD,Grossman N

更新日期：2005-02-01 00:00:00

abstract：:Ochronosis is an uncommon condition characterized by yellow-brown pigment deposits in the dermis. It occurs in exogenous and endogenous forms. We report a case of exogenous ochronosis in a Hispanic woman and discuss the different forms of this condition. We treated the lesions with Q-switched ruby laser. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kramer KE,Lopez A,Stefanato CM,Phillips TJ

更新日期：2000-05-01 00:00:00

abstract：:Our purpose was to evaluate, in an open study, the efficacy of epidermal equivalents (EEs), a tissue-engineered epidermis prepared from autologous hair follicle keratinocytes, for the treatment of recurrent leg ulcers (n = 50). To generate EEs, keratinocytes expanded from the outer root sheaths of plucked anagen hair ...

journal_title：Journal of the American Academy of Dermatology

authors： Limat A,French LE,Blal L,Saurat JH,Hunziker T,Salomon D

更新日期：2003-02-01 00:00:00

abstract：:Poison ivy, poison oak, and poison sumac are now classified in the genus Toxicodendron which is readily distinguished from Rhus. In the United States, there are two species of poison oak, Toxicodendron diversilobum (western poison oak) and Toxicodendron toxicarium (eastern poison oak). There are also two species of po...

journal_title：Journal of the American Academy of Dermatology

authors： Guin JD,Gillis WT,Beaman JH

更新日期：1981-01-01 00:00:00

abstract：:We describe hereditary progressive mucinous histiocytosis, a rare autosomal dominant non-Langerhans cell histiocytosis, in a mother and daughter. Both had similar, progressive eruptions of skin-colored to red-brown papules on the nose, hands, forearms, and thighs. Light microscopy showed small collections of epithelio...

journal_title：Journal of the American Academy of Dermatology

authors： Schröder K,Hettmannsperger U,Schmuth M,Orfanos CE,Goerdt S

更新日期：1996-08-01 00:00:00

abstract：:In 1987 the American Academy of Dermatology began to create Guidelines of Care for clinical disease processes in dermatology. The format of the guidelines has changed dramatically over the past several years; now all of the recent guidelines are in the evidence-based style. These guidelines have been recognized nation...

journal_title：Journal of the American Academy of Dermatology

authors： Van Voorhees AS

更新日期：2003-06-01 00:00:00

abstract：:Mycophenolate mofetil (MMF) has been widely used as an immunosuppressant in organ transplantation. MMF has recently been added to therapeutic regimens for skin disorders. Expanding the use of MMF in dermatology, we describe additional patients with autoimmune and inflammatory skin diseases, including 4 cases of pemphi...

journal_title：Journal of the American Academy of Dermatology

authors： Nousari HC,Sragovich A,Kimyai-Asadi A,Orlinsky D,Anhalt GJ

更新日期：1999-02-01 00:00:00

abstract：:We report a 38-year-old woman with lymphomatoid papulosis (LyP) who had nodular and papulovesicular lesions develop on the genital area and oral commissure. Mucosal involvement in LyP is a rare event, and its clinical relevance is still unknown. Aggressive therapies are not recommended in patients with LyP with either...

journal_title：Journal of the American Academy of Dermatology

authors： Chimenti S,Fargnoli MC,Pacifico A,Peris K

更新日期：2001-02-01 00:00:00

abstract：BACKGROUND:Although there is increased understanding of the alopecia areata (AA) pathogenesis based on studies in scalp tissues, little is known about its systemic profile. OBJECTIVE:To evaluate the blood proteomic signature of AA and determine biomarkers associated with increased disease severity. METHODS:In a cross...

journal_title：Journal of the American Academy of Dermatology

authors： Glickman JW,Dubin C,Renert-Yuval Y,Dahabreh D,Kimmel GW,Auyeung K,Estrada YD,Singer G,Krueger JG,Pavel AB,Guttman-Yassky E

更新日期：2021-02-01 00:00:00

abstract：BACKGROUND:Despite the prevalence of androgenetic alopecia among men, little is known about its psychological effects. OBJECTIVE:This investigation examined the psychosocial sequelae that balding men attribute to hair loss and compared balding and nonbalding men in personality functioning. METHODS:Subjects included 6...

journal_title：Journal of the American Academy of Dermatology

authors： Cash TF

更新日期：1992-06-01 00:00:00

abstract：:An acute localized, purulent skin lesion developed on the right knee of an 8-year-old girl and was subsequently diagnosed as a primary cutaneous Nocardia brasiliensis infection. It was soon accompanied by intense lymphangitis and regional adenopathy. The patient had a history of a minor abrasion contaminated by soil a...

journal_title：Journal of the American Academy of Dermatology

authors： Hironaga M,Mochizuki T,Watanabe S

更新日期：1990-08-01 00:00:00

abstract：:Skin toxicities are the most common side effects associated with the epidermal growth factor receptor inhibitor erlotinib, occurring in most patients receiving the drug. Clinical trials evaluating erlotinib for the treatment of non-small cell lung cancer have reported a range of skin disorders, the most common being a...

journal_title：Journal of the American Academy of Dermatology

authors： Kiyohara Y,Yamazaki N,Kishi A

更新日期：2013-09-01 00:00:00

abstract：:Good to excellent clinical results have been obtained in the treatment of severe inflammatory acne (acne conglobata, acne fulminans, and acne conglobata with hidradenitis and dissecting cellulitis of the scalp) with orally administered isotretinoin (13-cis-retinoic acid). Similar promising results have been obtained i...

journal_title：Journal of the American Academy of Dermatology

authors： Plewig G,Nikolowski J,Wolff HH

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:Inherited susceptibility genes have been associated with histopathologic characteristics of tumors. OBJECTIVE:We sought to identify associations between histology of melanomas and CDKN2A genotype. METHODS:This was a case-control study design comparing 28 histopathologic tumor features among individuals wit...

journal_title：Journal of the American Academy of Dermatology

authors： Sargen MR,Kanetsky PA,Newton-Bishop J,Hayward NK,Mann GJ,Gruis NA,Tucker MA,Goldstein AM,Bianchi-Scarra G,Puig S,Elder DE

更新日期：2015-03-01 00:00:00

abstract：:Current classifications for hidradenitis suppurativa (HS), such as the Hurley staging system, are not very specific. The absence of rigorous classifications is incongruous with the clinical variability of the condition. There is no pathognomonic sign for HS that leads to a diagnosis that is unquestionable. Consequentl...

journal_title：Journal of the American Academy of Dermatology

authors： van der Zee HH,Jemec GB

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:The efficacy of combination therapy with topical corticosteroids and tacrolimus in the treatment of atopic dermatitis remains to be established. OBJECTIVE:Our aim was to determine whether a regimen of sequential application of topical corticosteroids and topical tacrolimus is effective in the treatment of p...

journal_title：Journal of the American Academy of Dermatology

authors： Kubota Y,Yoneda K,Nakai K,Katsuura J,Moriue T,Matsuoka Y,Miyamoto I,Ohya Y

更新日期：2009-02-01 00:00:00

abstract：BACKGROUND:Many factors influence anxiety and satisfaction of patients undergoing Mohs micrographic surgery (MMS). OBJECTIVE:We sought to determine the effect of a preoperative educational telephone call on anxiety and satisfaction for patients undergoing same-day office consultation and MMS. METHODS:Patients with sk...

journal_title：Journal of the American Academy of Dermatology

authors： Sobanko JF,Da Silva D,Chiesa Fuxench ZC,Modi B,Shin TM,Etzkorn JR,Samimi SS,Wanat KA,Miller CJ

更新日期：2017-03-01 00:00:00

abstract：:Clinical trials are critical for the development of new therapies in dermatology, and their results help determine US Food and Drug Administration (FDA) approval and guide care. Of special relevance is the clinical trial efficacy end point, the metric from which statistically significant outcome is derived. Clinicians...

journal_title：Journal of the American Academy of Dermatology

authors： Wei EX,Kirsner RS,Eaglstein WH

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Port-wine stains (PWS) may thicken and darken with age. Little is known about the pathogenesis and epidemiology of PWS hypertrophy because of the lack of large studies. OBJECTIVE:We sought to assess the prevalence and characteristics of patients with hypertrophic PWS. METHODS:Medical records and clinical p...

journal_title：Journal of the American Academy of Dermatology

authors： van Drooge AM,Beek JF,van der Veen JP,van der Horst CM,Wolkerstorfer A

更新日期：2012-12-01 00:00:00

abstract：:Hutchinson's sign, periungual extension of brown-black pigmentation from longitudinal melanonychia onto the proximal and lateral nailfolds, is an important indicator of subungual melanoma. However, experience has demonstrated that Hutchinson's sign, although valuable, is not an infallible predictor of melanoma. Periun...

journal_title：Journal of the American Academy of Dermatology

authors： Baran R,Kechijian P

更新日期：1996-01-01 00:00:00

abstract：:Multiple modalities exist for the treatment of keratoacanthoma. Excisional surgery is currently the treatment of choice for the majority of keratoacanthomas. This can result in functional and cosmetic defects when large or strategically located lesions are treated. An effective nonsurgical treatment would be desirable...

journal_title：Journal of the American Academy of Dermatology

authors： Melton JL,Nelson BR,Stough DB,Brown MD,Swanson NA,Johnson TM

更新日期：1991-12-01 00:00:00

abstract：:Lobular capillary hemangioma and bacillary angiomatosis due to Bartonella infection share several clinical and histopathologic characteristics. We sought to determine whether lobular capillary hemangioma is caused by the same agent as bacillary angiomatosis. Forty-five pathology specimens with a histologic diagnosis o...

journal_title：Journal of the American Academy of Dermatology

authors： Levy I,Rolain JM,Lepidi H,Raoult D,Feinmesser M,Lapidoth M,Ben-Amitai D

更新日期：2005-12-01 00:00:00