Congenital curvilinear palpable hyperpigmentation.

abstract：BACKGROUND:Needle puncture and infiltrational anesthesia is generally required for minor cutaneous surgical procedures and may be associated with anxiety, fear, discomfort, and pain. The use of topical anesthetics such as eutectic lidocaine/prilocaine 5% cream may provide an alternative means of delivering anesthesia. ...

journal_title：Journal of the American Academy of Dermatology

authors： Gupta AK,Sibbald RG

更新日期：1996-09-01 00:00:00

abstract：:Eosinophilic spongiosis has a distinctive but not diagnostic histologic pattern of the epidermis. This pattern may be seen in a wide variety of clinical disorders. We have observed it most commonly in bullous pemphigoid, particularly the urticarial stage. In most biopsy specimens that show eosinophilic spongiosis, add...

journal_title：Journal of the American Academy of Dermatology

authors： Crotty C,Pittelkow M,Muller SA

更新日期：1983-03-01 00:00:00

abstract：:Psoriasis has been traditionally viewed as an inflammatory skin disorder of unknown origin. Recent advances in the immunopathogenesis and genetics of psoriasis have broadened our understanding of psoriasis. Psoriasis is now considered a systemic inflammatory condition analogous to other inflammatory immune disorders. ...

journal_title：Journal of the American Academy of Dermatology

authors： Kremers HM,McEvoy MT,Dann FJ,Gabriel SE

更新日期：2007-08-01 00:00:00

abstract：:A patient who developed exfoliative erythroderma 11 days after the initiation of hydroxychloroquine treatment for psoriatic arthritis is presented. Our experience with her and the continued controversy regarding the incidence of adverse reactions in psoriatic patients to antimalarials prompted a detailed review of the...

journal_title：Journal of the American Academy of Dermatology

authors： Slagel GA,James WD

更新日期：1985-05-01 00:00:00

abstract：OBJECTIVE:Tolerability and safety of 0.1% tacrolimus ointment in treating nickel-induced allergic contact dermatitis (ACD) were evaluated. METHODS:Patients allergic to nickel applied nickel patches to each upper inner aspect of the arm for 4 to 8 hours daily. Tacrolimus was applied to patch site on one arm and vehicle...

journal_title：Journal of the American Academy of Dermatology

authors： Belsito D,Wilson DC,Warshaw E,Fowler J,Ehrlich A,Anderson B,Strober BE,Willetts J,Rutledge ES

更新日期：2006-07-01 00:00:00

abstract：BACKGROUND:Treatment of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) remains controversial. OBJECTIVE:We sought to evaluate the impact of cyclosporine on hospital mortality in patients with SJS/TEN. METHODS:All patients with SJS and TEN admitted to our center from 2011 to 2014 were treated unde...

journal_title：Journal of the American Academy of Dermatology

authors： Lee HY,Fook-Chong S,Koh HY,Thirumoorthy T,Pang SM

更新日期：2017-01-01 00:00:00

abstract：:We report a case of a patient with scleromyxedema limited to the skin with an associated IgG lambda monoclonal protein treated successfully with high-dose dexamethasone. We encourage the continued investigation of this complex relationship between the clinical presentation of scleromyxedema and its frequently associat...

journal_title：Journal of the American Academy of Dermatology

authors： Horn KB,Horn MA,Swan J,Singhal S,Guitart J

更新日期：2004-08-01 00:00:00

abstract：:Vogt-Koyanagi-Harada disease is a rare disease characterized by uveitis, meningitis, dysacusis, alopecia, poliosis, and vitiligo. We describe a 48-year-old patient with Vogt-Koyanagi-Harada disease associated with thin inflammatory raised erythema and plaque-type inflammatory erythema superimposed on vitiligo. Interes...

journal_title：Journal of the American Academy of Dermatology

authors： Tsuruta D,Hamada T,Teramae H,Mito H,Ishii M

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Biologics targeting interleukin 17A (IL-17A) allow for rapid clearance of psoriatic plaques, with a clinically favorable safety profile. OBJECTIVES:To compare the safety and efficacy of ixekizumab, an IL-17A antagonist, with the safety and efficacy of the IL-12/23 inhibitor ustekinumab through 52 weeks of t...

journal_title：Journal of the American Academy of Dermatology

authors： Paul C,Griffiths CEM,van de Kerkhof PCM,Puig L,Dutronc Y,Henneges C,Dossenbach M,Hollister K,Reich K

更新日期：2019-01-01 00:00:00

abstract：BACKGROUND:Access to dermatologists is low among Medicaid-insured patients. Higher clinic nonattendance among Medicaid-insured patients might affect provider decisions to accept these patients. OBJECTIVE:To determine the effect of different scheduling policies on the attendance among children seen at a pediatric derma...

journal_title：Journal of the American Academy of Dermatology

authors： Chaudhry SB,Siegfried E,Sheikh UA,Simonetta C,Butala N,Armbrecht E

更新日期：2019-08-01 00:00:00

abstract：:Kawasaki disease, or mucocutaneous lymph node syndrome, is the leading cause of acquired heart disease in children in the United States and other developed countries. Coronary artery lesions are the most significant cause of morbidity and mortality. Treatment should ideally be provided within 10 days of symptom onset ...

journal_title：Journal of the American Academy of Dermatology

authors： Bayers S,Shulman ST,Paller AS

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Ultraviolet B phototherapy is underused because of costs and inconvenience. Home phototherapy may alleviate these issues, but training is spotty, and many physicians are not comfortable prescribing home phototherapy. OBJECTIVE:The purpose of this review is to provide a practical guide for recognizing approp...

journal_title：Journal of the American Academy of Dermatology

authors： Anderson KL,Feldman SR

更新日期：2015-05-01 00:00:00

abstract：BACKGROUND:Genetic and environmental components may contribute to acne causation. OBJECTIVE:We sought to assess the impact of family history, personal habits, dietary factors, and menstrual history on a new diagnosis of moderate to severe acne. METHODS:We conducted a case-control study in dermatologic outpatient clin...

journal_title：Journal of the American Academy of Dermatology

authors： Di Landro A,Cazzaniga S,Parazzini F,Ingordo V,Cusano F,Atzori L,Cutrì FT,Musumeci ML,Zinetti C,Pezzarossa E,Bettoli V,Caproni M,Lo Scocco G,Bonci A,Bencini P,Naldi L,GISED Acne Study Group.

更新日期：2012-12-01 00:00:00

abstract：:A 65-year-old woman treated with etretinate for pityriasis rubra pilaris developed chronic active hepatitis. The elevated transaminases were noted 2 months after initiation of therapy and peaked 2 months after discontinuation of etretinate. The spectrum of liver toxicity induced by etretinate is reviewed. We suggest t...

journal_title：Journal of the American Academy of Dermatology

authors： Sanchez MR,Ross B,Rotterdam H,Salik J,Brodie R,Freedberg IM

更新日期：1993-05-01 00:00:00

abstract：:We describe a family with the unusual association of Cowden's disease and Bannayan-Riley-Ruvalcaba syndrome. The father has characteristic mucocutaneous features that are palmoplantar keratoses, multiple facial papules, oral papillomatoses, lipomas, and vitiligo with involvement of the thyroid and digestive tract. The...

journal_title：Journal of the American Academy of Dermatology

authors： Perriard J,Saurat JH,Harms M

更新日期：2000-02-01 00:00:00

abstract：:This case describes an unusual presentation of dermatomyositis in a patient with ovarian carcinoma. The eruption appeared as a venous stasislike dermatitis. The temporal sequence of onset after chemotherapy administration suggested a possible drug-induced process. However, in the context of underlying ovarian carcinom...

journal_title：Journal of the American Academy of Dermatology

authors： Seidler AM,Wasserman DI,González-Serva A,Konnikov N

更新日期：2008-09-01 00:00:00

abstract：:The retinoids have been investigated extensively as chemopreventive and therapeutic agents in a variety of neoplasms. They have been shown to inhibit the proliferation of transformed cell lines in vitro and transplanted tumors in vivo. In cultured murine melanoma cells, retinoids inhibit proliferation and induce diffe...

journal_title：Journal of the American Academy of Dermatology

authors： Meyskens FL Jr,Edwards L,Levine NS

更新日期：1986-10-01 00:00:00

abstract：:Photodynamic therapy (PDT) is a treatment based on the accumulation of a photosensitizer in the target cells and their selective destruction by irradiation with visible light. In the past 10 years, several patients with cutaneous T cell lymphoma have been successfully treated. The use of PDT in cutaneous B cell lympho...

journal_title：Journal of the American Academy of Dermatology

authors： Mori M,Campolmi P,Mavilia L,Rossi R,Cappugi P,Pimpinelli N

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Recurrences after Mohs micrographic surgery (MMS) have been associated in the past with aggressive tumor type, large tumor size, and location within certain anatomic subunits. These factors are beyond the control of the treating physician and not subject to quality improvement efforts. OBJECTIVE:We sought t...

journal_title：Journal of the American Academy of Dermatology

authors： Campbell T,Armstrong AW,Schupp CW,Barr K,Eisen DB

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Treatment guidelines are lacking for classic Kaposi sarcoma. OBJECTIVE:We sought to review the evidence on efficacy of treatments for classic Kaposi sarcoma. METHODS:Articles published in English or French in MEDLINE, Trip, Cochrane Library, and Pascal databases from 1980 to December 2010 were screened. St...

journal_title：Journal of the American Academy of Dermatology

authors： Régnier-Rosencher E,Guillot B,Dupin N

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Although most patients with cutaneous melanoma are non-Hispanic whites (NHWs), minorities consistently suffer worse melanoma-specific survival (MSS). Much of the literature comes from analyses of registries from the 1990s and 2000s. OBJECTIVE:We sought to evaluate whether and to what degree racial disparity...

journal_title：Journal of the American Academy of Dermatology

authors： Qian Y,Johannet P,Sawyers A,Yu J,Osman I,Zhong J

更新日期：2020-08-27 00:00:00

abstract：:Melasma is an acquired brown hypermelanosis of the face. Although it is thought that melasma is associated with multiple etiologic factors (pregnancy, gastric, racial, and endocrine), one of the primary causes of its exacerbation appears to be exposure to sunlight. Three patterns of melasma are recognized clinically: ...

journal_title：Journal of the American Academy of Dermatology

authors： Sanchez NP,Pathak MA,Sato S,Fitzpatrick TB,Sanchez JL,Mihm MC Jr

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND:Nickel is a common allergen. OBJECTIVE:To examine the epidemiology of nickel sensitivity in North America. METHODS:Retrospective, cross-sectional analysis of 44,097 patients patch tested by the North American Contact Dermatitis Group from 1994 to 2014. Nickel sensitivity was defined as a positive patch tes...

journal_title：Journal of the American Academy of Dermatology

authors： Warshaw EM,Zhang AJ,DeKoven JG,Maibach HI,Belsito DV,Sasseville D,Fowler JF Jr,Fransway AF,Mathias T,Pratt MD,Marks JG Jr,Zug KA,Zirwas MJ,Taylor JS,DeLeo VA

更新日期：2019-03-01 00:00:00

abstract：:Onychomadesis is defined as spontaneous separation of the nail plate from the nail bed, beginning at its proximal end and resulting in the shedding of the nail. It has been associated with a variety of clinical settings, including systemic illnesses, generalized skin diseases, and drug therapies. There have been a sma...

journal_title：Journal of the American Academy of Dermatology

authors： Mehra A,Murphy RJ,Wilson BB

更新日期：2000-08-01 00:00:00

abstract：:Long-term penicillamine therapy has been associated with alterations in dermal elastic tissue. Well-described associated dermatoses include pseudo-pseudoxanthoma elasticum, acquired cutis laxa, elastosis perforans serpiginosa, and anetoderma. Histologically, "lumpy-bumpy" or "bramble-bush" morphologic changes of elast...

journal_title：Journal of the American Academy of Dermatology

authors： Lewis BK,Chern PL,Stone MS

更新日期：2009-04-01 00:00:00

abstract：BACKGROUND:The association of nonparaneoplastic pemphigus with comorbid hematologic malignancies has yet to be established. OBJECTIVE:To estimate the association between pemphigus and the common types of hematologic malignancies. METHODS:A cross-sectional study was conducted comparing pemphigus patients with age-, se...

journal_title：Journal of the American Academy of Dermatology

authors： Kridin K,Zelber-Sagi S,Comaneshter D,Batat E,Cohen AD

更新日期：2018-06-01 00:00:00

abstract：:Cutaneous fungal infections are a major source of morbidity in HIV-infected patients, and their management poses special challenges. Superficial mycoses, such as tinea pedis, tinea cruris, tinea corporis, and onychomycosis, are no more common in HIV-infected patients than in the HIV-negative population but are of grea...

journal_title：Journal of the American Academy of Dermatology

authors： Elmets CA

更新日期：1994-09-01 00:00:00

abstract：:Three siblings with infantile-onset biotin-responsive multiple carboxylase deficiency are described. Recognition of the characteristic dermatologic manifestations, alopecia and periorificial dermatitis, should result in early diagnosis and institution of potentially lifesaving therapy with biotin. Other metabolic diso...

journal_title：Journal of the American Academy of Dermatology

authors： Williams ML,Packman S,Cowan MJ

更新日期：1983-07-01 00:00:00

abstract：:Patients with HIV and AIDS are living longer because of advancements in antiretroviral therapy. These patients are often susceptible to debilitating inflammatory disorders that are refractory to standard treatment. We discuss the relationship of tumor necrosis factor-alpha and HIV and then review 27 published cases of...

journal_title：Journal of the American Academy of Dermatology

authors： Gallitano SM,McDermott L,Brar K,Lowenstein E

更新日期：2016-05-01 00:00:00

abstract：:Pilomatrix carcinomas are rare neoplasms of the skin that may be locally aggressive or metastatic. The differentiation of these tumors from benign pilomatrixomas depends on a constellation of microscopic features, some of which may be equivocal or absent in individual biopsy specimens. We encountered a tumor with dist...

journal_title：Journal of the American Academy of Dermatology

authors： Rabkin MS,Wittwer CT,Soong VY

更新日期：1990-07-01 00:00:00