Fatal pancreatitis presenting with subcutaneous fat necrosis. Evidence that lipase and amylase alone do not induce lipocyte necrosis.

abstract：:We report a case of atypical Reiter's syndrome occurring in a female patient who had severe, ulcerative vulvar disease develop in association with conjunctivitis, low back pain, stomatitis, and psoriasiform skin lesions. Vulvar lesions have rarely been described in Reiter's syndrome and are not well characterized. ...

journal_title：Journal of the American Academy of Dermatology

authors： Lotery HE,Galask RP,Stone MS,Sontheimer RD

更新日期：2003-04-01 00:00:00

abstract：:Three clinicopathologic variants of lichen planopilaris are described. The first is characterized clinically by individual keratotic follicular papules and histologically by a lichenoid inflammatory cell infiltrate confined to the follicular epithelium. The second variant consists of erythematous to violaceous plaques...

journal_title：Journal of the American Academy of Dermatology

authors： Matta M,Kibbi AG,Khattar J,Salman SM,Zaynoun ST

更新日期：1990-04-01 00:00:00

abstract：BACKGROUND:Vitiligo is an autoimmune disease of the skin with limited treatment options; there is an urgent need to identify and validate biomarkers of disease activity to support vitiligo clinical studies. OBJECTIVE:To investigate potential biomarkers of disease activity directly in the skin of vitiligo subjects and ...

journal_title：Journal of the American Academy of Dermatology

authors： Strassner JP,Rashighi M,Ahmed Refat M,Richmond JM,Harris JE

更新日期：2017-05-01 00:00:00

abstract：BACKGROUND:Most biopsy specimens of cicatricial (scarring) alopecia can be readily subclassified as lymphocytic versus neutrophilic, but specific diagnosis remains difficult, particularly when a late stage of the disease is sampled. OBJECTIVE:We sought to document patterns of scarring highlighted by elastic tissue sta...

journal_title：Journal of the American Academy of Dermatology

authors： Fung MA,Sharon VR,Ratnarathorn M,Konia TH,Barr KL,Mirmirani P

更新日期：2013-11-01 00:00:00

abstract：BACKGROUND:Drug-specific T cells are involved in the pathogenesis of cutaneous adverse drug reactions (CADRs). OBJECTIVE:We sought to evaluate the diagnostic role of in vitro drug-induced release of interferon gamma in CADRs. METHODS:The study group consisted of 36 patients with CADRs after intake of 106 drugs that w...

journal_title：Journal of the American Academy of Dermatology

authors： Halevy S,Cohen AD,Grossman N

更新日期：2005-02-01 00:00:00

abstract：INTRODUCTION:Low-dose total skin electron beam therapy provides a durable treatment response for skin lesions caused by cutaneous T-cell lymphoma. We prospectively assessed the durability of response and quality of life for patients receiving low-dose total skin electron beam therapy using a novel rotational technique ...

journal_title：Journal of the American Academy of Dermatology

authors： Newman NB,Patel CG,Ding GX,Zic JA,Zwerner J,Osmundson EC,Kirschner AN

更新日期：2020-12-14 00:00:00

abstract：:Two patients with a hypersensitivity vasculitis in association with propylthiouracil (PTU) administration are described. Although both patients presented with a cutaneous eruption, our first patient suffered severe systemic manifestations and the second patient's involvement was primarily limited to the skin. Patients...

journal_title：Journal of the American Academy of Dermatology

authors： Chastain MA,Russo GG,Boh EE,Chastain JB,Falabella A,Millikan LE

更新日期：1999-11-01 00:00:00

abstract：:Many physicians in the United States and other nonendemic countries lack familiarity with New World cutaneous leishmaniasis (CL) and fail to include it in their differential diagnosis when seeing patients with suggestive lesions and recent high-risk travel. Moreover, even when the diagnosis of New World CL is consider...

journal_title：Journal of the American Academy of Dermatology

authors： Zaghi D,Panosian C,Gutierrez MA,Gregson A,Taylor E,Ochoa MT

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Few effective treatments are available for male pattern hair loss (MPHL) or, especially, for female pattern hair loss (FPHL). Recently, cell-based therapies using autologous or allogeneic cells have been used clinically. OBJECTIVE:We examined the safety and efficacy of autologous cell-based therapy using de...

journal_title：Journal of the American Academy of Dermatology

authors： Tsuboi R,Niiyama S,Irisawa R,Harada K,Nakazawa Y,Kishimoto J

更新日期：2020-07-01 00:00:00

abstract：:We describe a patient with hypereosinophilic syndrome, who had severe cutaneous eruptions. Immunohistochemical study revealed that dermal endothelial cells in the lesional skin of this patient expressed eotaxin, which indicates eotaxin plays a part in inducing eosinophil migration into cutaneous tissue in hypereosinop...

journal_title：Journal of the American Academy of Dermatology

authors： Tsunemi Y,Idezuki T,Nakamura K,Tamaki K

更新日期：2003-11-01 00:00:00

abstract：:Follicular mucinosis is often associated with mycosis fungoides and has been rarely observed to occur with other neoplastic and inflammatory conditions. We describe a 60-year-old patient with follicular mucinosis who later developed acute myelogenous leukemia. This is the first reported case of follicular mucinosis as...

journal_title：Journal of the American Academy of Dermatology

authors： Sumner WT,Grichnik JM,Shea CR,Moore JO,Miller WS,Burton CS

更新日期：1998-05-01 00:00:00

abstract：BACKGROUND:Bioflavonoids and ascorbic acid have been shown to increase capillary resistance and to mediate potent antioxidative radical scavenging activities. OBJECTIVE:We evaluated the clinical effect of oral bioflavonoids and ascorbic acid in patients with chronic progressive pigmented purpura (PPP). METHODS:In an ...

journal_title：Journal of the American Academy of Dermatology

authors： Reinhold U,Seiter S,Ugurel S,Tilgen W

更新日期：1999-08-01 00:00:00

abstract：BACKGROUND:Incomplete Mohs micrographic surgery (MMS) is the cessation of MMS while the tumor margins are known to be still positive. OBJECTIVE:Our purpose was to examine the factors behind unplanned incomplete MMS and to identify means of avoiding and managing this situation when it arises. METHODS:We performed a re...

journal_title：Journal of the American Academy of Dermatology

authors： Madani S,Huilgol SC,Carruthers A

更新日期：2000-05-01 00:00:00

abstract：BACKGROUND:BRAF mutations occur in some melanomas. We hypothesized that BRAF mutation rates may differ in melanomas found in Asian compared to white populations. OBJECTIVE:We performed a metaanalysis of BRAF mutations and their associations with the clinicopathologic characteristics of primary melanoma (PM), with a su...

journal_title：Journal of the American Academy of Dermatology

authors： Kim SY,Kim SN,Hahn HJ,Lee YW,Choe YB,Ahn KJ

更新日期：2015-06-01 00:00:00

abstract：:Renewed interest in experimental photocarcinogenesis was stimulated by the observation that skin cancers induced in mice by ultraviolet radiation are highly antigenic. Most of these cancers are rejected by the immune system on transplantation into a normal, genetically identical animal. This finding raised the questio...

journal_title：Journal of the American Academy of Dermatology

authors： Kripke ML

更新日期：1986-01-01 00:00:00

abstract：:Cultured epidermal sheets were examined before and at various times after grafting on skin ulcer beds. Before grafting, the sheet consisted of four to five layers of keratinocytes with incomplete differentiation. Ten days after grafting, graft recipient sites showed compact hyperkeratosis, a normal-appearing epidermis...

journal_title：Journal of the American Academy of Dermatology

authors： Phillips TJ,Bhawan J,Leigh IM,Baum HJ,Gilchrest BA

更新日期：1990-08-01 00:00:00

abstract：:Dialogues in Dermatology, a monthly audio program from the American Academy of Dermatology, contains discussions between dermatologists on timely dermatologic topics. Commentaries from the Dialogues Editor-in-Chief, Warren R. Heymann, MD, are provided after each discussion as a topic summary. These highlights are prov...

journal_title：Journal of the American Academy of Dermatology

authors： Heymann WR

更新日期：2004-07-01 00:00:00

abstract：:Global temperatures continue to rise, reaching new records almost every year this decade. Although the causes are debated, climate change is a reality. Consequences of climate change include melting of the arctic ice cap, rising of sea levels, changes in precipitation patterns, and increased severe weather events. Thi...

journal_title：Journal of the American Academy of Dermatology

authors： Kaffenberger BH,Shetlar D,Norton SA,Rosenbach M

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:The eruptive appearance of numerous seborrheic keratoses, the sign of Leser-Trélat, has been regarded as a reliable cutaneous marker of internal malignancy. OBJECTIVE:We have evaluated the possible association of malignant disease and the sign in 1752 consecutive cases of seborrheic keratoses. METHODS:Firs...

journal_title：Journal of the American Academy of Dermatology

authors： Lindelöf B,Sigurgeirsson B,Melander S

更新日期：1992-06-01 00:00:00

abstract：:The psychosocial impact of infection with human immunodeficiency virus (HIV) can be viewed from three perspectives: (1) the issues focused by acquired immunodeficiency syndrome (AIDS), (2) the persons affected, and (3) the emotions encountered. Among the many issues faced by AIDS patients, their families, and their ca...

journal_title：Journal of the American Academy of Dermatology

authors： Cline DJ

更新日期：1990-06-01 00:00:00

abstract：BACKGROUND:Patients with cutaneous lupus erythematosus (LE) and a history of disease- related photoaggravation, confirmed by phototesting, may not respond to photoprotection and/or medical intervention. Ultraviolet B-hardening therapy may improve tolerance for environmental ultraviolet radiation (UVR) in photosensitive...

journal_title：Journal of the American Academy of Dermatology

authors： Sanders CJ,Lam HY,Bruijnzeel-Koomen CA,Sigurdsson V,van Weelden H

更新日期：2006-03-01 00:00:00

abstract：:A recent study demonstrated that hirsute women with irregular menses had higher levels of serum androgens that hirsute women with regular menses. To investigate this finding, we measured total testosterone, biologically active testosterone, free testosterone, androstenedione, dehydroepiandrosterone, and dehydroepiandr...

journal_title：Journal of the American Academy of Dermatology

authors： Salman K,Spielvogel RL,Miller JL,Rose LI

更新日期：1991-03-01 00:00:00

abstract：:Forty-seven patients with chronic venous leg ulcers were included in a randomized clinical trial to evaluate the efficacy of systemically administered antibiotics in healing with condition. One group was treated by means of elastic support bandages only, whereas the other one received the same local treatment plus sys...

journal_title：Journal of the American Academy of Dermatology

authors： Alinovi A,Bassissi P,Pini M

更新日期：1986-08-01 00:00:00

abstract：BACKGROUND:Mycoplasma pneumoniae infection is associated with extrapulmonary complications, including mucocutaneous eruptions. These eruptions, which have been termed either "Stevens-Johnson syndrome" or "erythema multiforme" in the literature, may differ from drug-induced Stevens-Johnson syndrome or viral-associated e...

journal_title：Journal of the American Academy of Dermatology

authors： Canavan TN,Mathes EF,Frieden I,Shinkai K

更新日期：2015-02-01 00:00:00

abstract：:A set of three comparison studies under varying conditions was performed to determine the efficacy of a cotton swab technic for obtaining material for culture of dermatophyte infections. Matched fungal cultures, one by swab and one by scrape, on each of 110 subjects showed that there was no difference in the two metho...

journal_title：Journal of the American Academy of Dermatology

authors： Head ES,Henry JC,Macdonald EM

更新日期：1984-11-01 00:00:00

abstract：:Incontinentia pigmenti is a rare genodermatosis of unknown etiology. A female infant with features typical of this disease was found to have basophils in early vesicular lesions. Mediators from these cells may be responsible for the accumulation of eosinophils in these lesions. ...

journal_title：Journal of the American Academy of Dermatology

authors： Schmalstieg FC,Jorizzo JL,Tschen J,Subrt P

更新日期：1984-02-01 00:00:00

abstract：:Cutaneous metastases present themselves in a variety of clinical patterns and tend to be manifested as indurated papules/nodules/tumors. Some of those clinical expressions are unique for certain types of metastases. This report describes an entirely different phenomenon of clinically incognito cutaneous metastases tha...

journal_title：Journal of the American Academy of Dermatology

authors： Resnik KS,DiLeonardo M,Gibbons G

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Despite a lack of evidence that dysplastic nevi are precursors to melanoma, a large proportion of dermatologists continue to treat them as such. Emerging data suggest that histologic grading approach may result in many unnecessary excisions. OBJECTIVE:Using a nongrading approach to diagnosis of Clark/dyspla...

journal_title：Journal of the American Academy of Dermatology

authors： Lozeau DF,Farber MJ,Lee JB

更新日期：2016-01-01 00:00:00

abstract：:The increased use of isotretinoin therapy for severe cystic acne has posed new problems for dermatologic surgeons. There have been recent reports in the literature of unexpected "atypical" scarring after dermabrasion in patients who have previously taken isotretinoin. This scarring was considered atypical because it o...

journal_title：Journal of the American Academy of Dermatology

authors： Katz BE,Mac Farlane DF

更新日期：1994-05-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD), a disease with both inherited and environmental components determining its clinical expression, has been reported to be more frequent in people of Asian origin. OBJECTIVE:Our purpose was to compare the 12-month cumulative incidence of AD in Caucasian, Chinese, and Vietnamese babies b...

journal_title：Journal of the American Academy of Dermatology

authors： Mar A,Tam M,Jolley D,Marks R

更新日期：1999-04-01 00:00:00