Elastin staining patterns in primary cicatricial alopecia.

abstract：:Chronic mucocutaneous candidiasis is a complex disorder in which patients have chronic and recurrent Candida albicans infections of the skin, nails, and mucous membranes. There are several subgroups of patients with chronic mucocutaneous candidiasis, and these can be identified by associated disorders such as autoimmu...

journal_title：Journal of the American Academy of Dermatology

authors： Kirkpatrick CH

更新日期：1994-09-01 00:00:00

abstract：:Zinc is a trace element essential to the gastrointestinal, immune, integumentary, reproductive, and central nervous systems. Zinc deficiency is prevalent in many areas of the world and is a diagnostically challenging condition. Cutaneous manifestations typically occur in moderate to severe zinc deficiency and present ...

journal_title：Journal of the American Academy of Dermatology

authors： Corbo MD,Lam J

更新日期：2013-10-01 00:00:00

abstract：BACKGROUND:Despite recommendations to limit the use of oral antibiotics and increasing support for hormonal agents in the treatment of acne, it is unclear whether there have been any significant changes in practice patterns. OBJECTIVE:To characterize changes in prescribing behavior for systemic agents in the treatment...

journal_title：Journal of the American Academy of Dermatology

authors： Barbieri JS,James WD,Margolis DJ

更新日期：2017-09-01 00:00:00

abstract：:The hemophagocytic syndrome (HPS) was first described in immune-compromised patients with secondary viral infections. Immunodeficiency has not always been diagnosed before the onset of HPS, but most patients who develop HPS have known immune deficits. HPS has also been reported in association with lymphoreticular mali...

journal_title：Journal of the American Academy of Dermatology

authors： Smith KJ,Skelton HG 3rd,Giblin WL,James WD

更新日期：1991-11-01 00:00:00

abstract：BACKGROUND:Granuloma annulare is a common skin disorder that usually presents with smooth papules arranged as annular plaques. Variants, such as disseminated, subcutaneous, and perforating granuloma annulare, have been described. OBJECTIVE:The purpose of this study is to describe the clinical and histologic features o...

journal_title：Journal of the American Academy of Dermatology

authors： Mutasim DF,Bridges AG

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Reports suggest that cigarette smoking might interfere with the effectiveness of antimalarial therapy as first-line treatment for cutaneous lupus erythematosus. Patients refractory to this treatment often must be treated with potentially more toxic regimens. OBJECTIVE:Our purpose was to examine the effects ...

journal_title：Journal of the American Academy of Dermatology

authors： Jewell ML,McCauliffe DP

更新日期：2000-06-01 00:00:00

abstract：:With increasingly widespread use of cyclosporine for the treatment of psoriasis, it is imperative to identify reliable markers of cyclosporine-induced nephrotoxicity. Five patients with extensive psoriasis and no significant preexisting renal disease were treated with oral cyclosporine (average dosage, 5 mg/kg per day...

journal_title：Journal of the American Academy of Dermatology

authors： Gilbert SC,Emmett M,Menter A,Silverman A,Klintmalm G

更新日期：1989-09-01 00:00:00

abstract：:Neutrophilic dermatosis developed in two patients with myelodysplastic syndrome. Biopsy specimens of their skin lesions showed marked infiltration by neutrophils with nuclear anomalies, that is, hyposegmentation (pseudo-Pelger-Huët anomaly) or hypersegmentation. Peripheral blood and bone marrow neutrophils had similar...

journal_title：Journal of the American Academy of Dermatology

authors： Morioka N,Otsuka F,Nogita T,Igisu K,Urabe A,Ishibashi Y

更新日期：1990-08-01 00:00:00

abstract：:A case is presented in which a patient experienced the development of both Dupuytren's disease and Peyronie's disease after single episodes of sports-related trauma. These disorders and other fibromatoses are linked not only by similar pathologic features but by increased frequency of simultaneous occurrence. Some gen...

journal_title：Journal of the American Academy of Dermatology

authors： Connelly TJ

更新日期：1999-07-01 00:00:00

abstract：:A persistent periocular dermatitis resulting from the prolonged use of topical fluorinated corticosteroids that resembled the perioral variety was observed in three patients. All topical therapy was ineffective until systemic tetracycline was administered. ...

journal_title：Journal of the American Academy of Dermatology

authors： Fisher AA

更新日期：1986-10-01 00:00:00

abstract：:We studied the effects of two retinoids, naturally occurring all-trans-retinoic acid (retinoic acid) and the synthetic 4-hydroxyphenylretinamide (4-OH-PRT) on monolayer cultures of rabbit synovial fibroblasts and on explants of rabbit articular cartilage. Treatment of fibroblasts with phorbol myristate acetate (PMA; 1...

journal_title：Journal of the American Academy of Dermatology

authors： Brinckerhoff CE,Nagase H,Nagel JE,Harris ED Jr

更新日期：1982-04-01 00:00:00

abstract：BACKGROUND:Sturge-Weber syndrome (SWS) is characterized by port-wine stains (PWS) affecting the face, eyes, and central nervous system. Pulsed dye laser (PDL) is the standard treatment for PWS. Unfortunately, recurrence is frequent because of reformation and reperfusion of blood vessels. OBJECTIVE:We sought to assess ...

journal_title：Journal of the American Academy of Dermatology

authors： Marqués L,Núñez-Córdoba JM,Aguado L,Pretel M,Boixeda P,Nagore E,Baselga E,Redondo P

更新日期：2015-01-01 00:00:00

abstract：:Vogt-Koyanagi-Harada disease is a rare disease characterized by uveitis, meningitis, dysacusis, alopecia, poliosis, and vitiligo. We describe a 48-year-old patient with Vogt-Koyanagi-Harada disease associated with thin inflammatory raised erythema and plaque-type inflammatory erythema superimposed on vitiligo. Interes...

journal_title：Journal of the American Academy of Dermatology

authors： Tsuruta D,Hamada T,Teramae H,Mito H,Ishii M

更新日期：2001-01-01 00:00:00

abstract：:We review experimental studies that address age-related changes in cutaneous barrier function and dermal blood vessel function. These differences have important implications in the understanding of age-related changes in the inflammatory process and topical drug delivery systems. ...

journal_title：Journal of the American Academy of Dermatology

authors： Harvell JD,Maibach HI

更新日期：1994-12-01 00:00:00

abstract：BACKGROUND:Intertriginous and facial involvement are manifestations of psoriasis that require a different approach than is used for typical plaque psoriasis on other skin areas. Topical corticosteroids are the primary treatment for psoriasis; however, the side effects of corticosteroids are magnified on intertriginous ...

journal_title：Journal of the American Academy of Dermatology

authors： Lebwohl M,Freeman AK,Chapman MS,Feldman SR,Hartle JE,Henning A,Tacrolimus Ointment Study Group.

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:There is a lack of data on outcomes of management of pemphigus in children. OBJECTIVE:We sought to evaluate rituximab treatment in childhood and juvenile pemphigus. METHOD:All cases of pemphigus treated with rituximab in patients younger than 18 years were included. Clinical and epidemiologic data and deta...

journal_title：Journal of the American Academy of Dermatology

authors： Vinay K,Kanwar AJ,Sawatkar GU,Dogra S,Ishii N,Hashimoto T

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:Atypical fibroxanthoma (AFX) is a fibrohistiocytic tumor with relatively high local recurrence rates but low metastatic potential. Wide local excision (WLE) and Mohs micrographic surgery (MMS) are common treatments, although no consensus exists regarding optimal therapy. OBJECTIVE:To systematically review e...

journal_title：Journal of the American Academy of Dermatology

authors： Tolkachjov SN,Kelley BF,Alahdab F,Erwin PJ,Brewer JD

更新日期：2018-11-01 00:00:00

abstract：:We report a patient with a vesiculopustular eruption with features distinct from typical subcorneal pustular dermatosis. Clinically, well-formed pustular lesions, which were flowerlike in appearance, were present. Histopathologically, early vesicular lesions showed intraepidermal bullae containing numerous neutrophils...

journal_title：Journal of the American Academy of Dermatology

authors： Kuan YZ,Chiou HT,Chang HC,Chan HL,Kuo TT

更新日期：1990-05-01 00:00:00

abstract：:The diagnostic value of parakeratosis is reviewed, with special emphasis on associated inflammatory tissue reaction patterns and the geometric pattern of the scale. Parakeratosis may also occur in disorders not primarily inflammatory in nature and those associations are addressed. Topics are divided into 6 categories:...

journal_title：Journal of the American Academy of Dermatology

authors： Brady SP

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Scleredema adultorum (SA) is a rare connective tissue disorder for which no treatment has proven to be effective. OBJECTIVE:Our purpose was to determine the effect of bath-PUVA therapy on SA. METHODS:Three patients were treated. Clinical evaluation of skin induration and thickness as well as ultrasonograph...

journal_title：Journal of the American Academy of Dermatology

authors： Hager CM,Sobhi HA,Hunzelmann N,Wickenhauser C,Scharenberg R,Krieg T,Scharffetter-Kochanek K

更新日期：1998-02-01 00:00:00

abstract：:Hyperkeratinization is a primary or fundamental event in a majority of today's skin disorders. Hyperkeratinization is usually the result of decreased desquamation due to increased corneocyte cohesion. Strength of corneocyte cohesion is determined by strength of intercellular bonding. Intercellular bonding is weakened ...

journal_title：Journal of the American Academy of Dermatology

authors： Van Scott EJ,Yu RJ

更新日期：1984-11-01 00:00:00

abstract：BACKGROUND:T-cell receptor (TCR) clonality may help establish a diagnosis of mycosis fungoides (MF). Routine clonality analysis is performed by using a polymerase chain reaction TCR- gamma assay, yet with this method, 10% to 50% of T-cell lymphomas escape detection. TCR- beta gene rearrangement is an additional assay. ...

journal_title：Journal of the American Academy of Dermatology

authors： Schachter O,Tabibian-Keissar H,Debby A,Segal O,Baum S,Barzilai A

更新日期：2020-11-01 00:00:00

abstract：:Chemexfoliation (chemical peeling) is being used to obtain both therapeutic (e.g., actinic keratoses) and cosmetic (e.g., removal of fine facial rhytides) benefits. Phenol, one of the most widely used agents for inducing cutaneous exfoliation, may induce cardiac arrhythmias and is toxic to the liver and kidneys. Trich...

journal_title：Journal of the American Academy of Dermatology

authors： Lober CW

更新日期：1987-07-01 00:00:00

abstract：:A 7.3-year prospective study of 1,380 patients with psoriasis who were treated with oral methoxsalen (8-methoxypsoralen) and ultraviolet A photochemotherapy (PUVA) revealed that patients who continued on PUVA therapy used inpatient hospital treatment less than one fourth as often as those who had discontinued treatmen...

journal_title：Journal of the American Academy of Dermatology

authors： Stern RS

更新日期：1986-03-01 00:00:00

abstract：BACKGROUND:Current treatments for vitiligo, a common pigmentary disorder affecting around 1% of the world's population, are largely unsatisfactory. OBJECTIVE:We sought to report a Cochrane review of all interventions for the treatment of vitiligo. METHODS:We systematically searched a range of databases for randomized...

journal_title：Journal of the American Academy of Dermatology

authors： Whitton ME,Ashcroft DM,González U

更新日期：2008-10-01 00:00:00

abstract：:A newcomer in the cosmetic market, the tan accelerator, has stimulated much publicity in recent months. We studied the effects of two brands of this product, used according to package instructions, in eighteen healthy volunteers. Readings at 24, 72, 96 hours, and 1 week failed to show augmented tanning. Our study cont...

journal_title：Journal of the American Academy of Dermatology

authors： Jaworsky C,Ratz JL,Dijkstra JW

更新日期：1987-04-01 00:00:00

abstract：BACKGROUND:The negative pigment network (NPN) is seen as a negative of the pigmented network and it is purported to be a melanoma-specific structure. OBJECTIVES:We sought to assess the frequency, sensitivity, specificity, and odds ratios (ORs) of NPN between melanoma cases and a group of control lesions. METHODS:Digi...

journal_title：Journal of the American Academy of Dermatology

authors： Pizzichetta MA,Talamini R,Marghoob AA,Soyer HP,Argenziano G,Bono R,Corradin MT,De Giorgi V,Gonzalez MA,Kolm I,Kopf AW,Malvehy J,Nami N,Oliviero M,Pellacani G,Puig S,Rabinovitz H,Rubegni P,Seidenari S,Stanganelli I,

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Appropriate primary end points in randomized controlled trials (RCTs) improve the quality of the measurement and enable comparison of the findings with those of other trials. OBJECTIVE:To assess the quality of reporting primary end points in RCTs recently published in dermatology journals. METHODS:We ident...

journal_title：Journal of the American Academy of Dermatology

authors： Kim DY,Oh S,Yoon HS

更新日期：2020-04-22 00:00:00

abstract：BACKGROUND:Conventional therapy of severe bullous pemphigoid (BP) relies on the use of high-dose systemic corticosteroids with or without adjuvants, notably immunosuppressive agents. This approach can result in debilitating and potentially fatal side effects, hence the need to explore alternative therapies. Intravenous...

journal_title：Journal of the American Academy of Dermatology

authors： Engineer L,Ahmed AR

更新日期：2001-01-01 00:00:00

abstract：BACKGROUND:Lentigo maligna (LM) is a relatively common tumor with increasing prevalence and substantial morbidity. A variety of treatment modalities are available, though margin-control surgery offers the highest cure rate. We were interested in comparing long-term outcomes of Mohs micrographic surgery (MMS) versus sta...

journal_title：Journal of the American Academy of Dermatology

authors： Walling HW,Scupham RK,Bean AK,Ceilley RI

更新日期：2007-10-01 00:00:00