How should we define itching?

abstract：BACKGROUND:Scleredema adultorum (SA) is a rare connective tissue disorder for which no treatment has proven to be effective. OBJECTIVE:Our purpose was to determine the effect of bath-PUVA therapy on SA. METHODS:Three patients were treated. Clinical evaluation of skin induration and thickness as well as ultrasonograph...

journal_title：Journal of the American Academy of Dermatology

authors： Hager CM,Sobhi HA,Hunzelmann N,Wickenhauser C,Scharenberg R,Krieg T,Scharffetter-Kochanek K

更新日期：1998-02-01 00:00:00

abstract：BACKGROUND:Confluent and reticulated papillomatosis (CRP) of Gougerot and Carteaud is an uncommon disorder of unknown cause for which a variety of treatments have been proposed. OBJECTIVE:We attempted to evaluate the effectiveness of oral minocycline. METHODS:Nine patients with CRP were treated with oral minocycline,...

journal_title：Journal of the American Academy of Dermatology

authors： Montemarano AD,Hengge M,Sau P,Welch M

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:There is a lack of data on outcomes of management of pemphigus in children. OBJECTIVE:We sought to evaluate rituximab treatment in childhood and juvenile pemphigus. METHOD:All cases of pemphigus treated with rituximab in patients younger than 18 years were included. Clinical and epidemiologic data and deta...

journal_title：Journal of the American Academy of Dermatology

authors： Vinay K,Kanwar AJ,Sawatkar GU,Dogra S,Ishii N,Hashimoto T

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The vulvovaginal gingival syndrome is an uncommon and severe variant of lichen planus characterized by erosions or desquamation of vulval, vaginal, and gingival mucosae with a predilection for scarring and stricture formation. OBJECTIVE:We sought to define the clinical, immunopathologic, and human leukocyte...

journal_title：Journal of the American Academy of Dermatology

authors： Setterfield JF,Neill S,Shirlaw PJ,Theron J,Vaughan R,Escudier M,Challacombe SJ,Black MM

更新日期：2006-07-01 00:00:00

abstract：:During the past two decades, systemic μ-opioid receptor antagonists (MORA) have been used in the treatment of various forms of chronic pruritus. In a number of case reports, case series, and controlled trials, treatment with MORA has demonstrated considerable antipruritic effects. In double-blind controlled studies, s...

journal_title：Journal of the American Academy of Dermatology

authors： Phan NQ,Bernhard JD,Luger TA,Ständer S

更新日期：2010-10-01 00:00:00

abstract：:A single application (16 to 20 hours) of 1% gamma benzene hexachloride (GBH) lotion, when applied to a total island population of 178 persons in which seventy-four clinically had scabies, resulted in a cure rate of over 98%. Re-examination of the population at 10 and 21 weeks revealed only one remaining individual sti...

journal_title：Journal of the American Academy of Dermatology

authors： Taplin D,Arrue C,Walker JG,Roth WI,Rivera A

更新日期：1983-10-01 00:00:00

abstract：:The safety and efficacy of 0.1% tacrolimus ointment for the treatment of psoriasis on the face, intertriginous areas, or both were evaluated in an open-label, clinical trial of 21 patients with psoriasis. Patients applied 0.1% tacrolimus ointment twice daily for 8 weeks. Efficacy was assessed through the investigator'...

journal_title：Journal of the American Academy of Dermatology

authors： Freeman AK,Linowski GJ,Brady C,Lind L,Vanveldhuisen P,Singer G,Lebwohl M

更新日期：2003-04-01 00:00:00

abstract：:Human papillomavirus infection is one of the most common and most distressing cutaneous diseases in patients with HIV infection. It is also a common, and often therapeutically challenging, infection in individuals who are immunologically competent. A wide range of therapeutic options exists for treating cutaneous huma...

journal_title：Journal of the American Academy of Dermatology

authors： Kottke MD,Parker SR

更新日期：2006-09-01 00:00:00

abstract：:The number of cases of mycotic infections are increasing, presenting physicians today with an unprecedented challenge in handling the treatment and prophylactic control of these disorders. The increase in mycotic disorders is due to many factors, such as longer life span, organ transplantation, and the acquired immuno...

journal_title：Journal of the American Academy of Dermatology

authors： Jacobs PH

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Antibodies against transcriptional intermediary factor (TIF)-1γ are associated with malignancy in dermatomyositis (DM). Identification of clinical findings associated with anti-TIF-1γ antibodies in DM is a high priority for both patient diagnosis and risk assessment. OBJECTIVE:We sought to define the clinic...

journal_title：Journal of the American Academy of Dermatology

authors： Fiorentino DF,Kuo K,Chung L,Zaba L,Li S,Casciola-Rosen L

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND:Effective medical treatment for patients with severe hidradenitis suppurativa (HS) is limited. OBJECTIVES:We sought to measure the impact of wide local excision on quality of life in HS Hurley grade III patients and to examine the rate of postoperative complications, disease recurrences, and satisfaction wi...

journal_title：Journal of the American Academy of Dermatology

authors： Posch C,Monshi B,Quint T,Vujic I,Lilgenau N,Rappersberger K

更新日期：2017-07-01 00:00:00

abstract：:We used an avidin-biotin complex immunoperoxidase technique with various monoclonal antibodies to determine Langerhans cell densities, class II antigen expression on keratinocytes, and phenotypes of other infiltrating cells in several malignant and benign epithelial tumors of the skin. Our observations indicate (1) th...

journal_title：Journal of the American Academy of Dermatology

authors： Chen HD,Zhao YM,Sun G,Yang CY

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:Atopic dermatitis (AD), a disease with both inherited and environmental components determining its clinical expression, has been reported to be more frequent in people of Asian origin. OBJECTIVE:Our purpose was to compare the 12-month cumulative incidence of AD in Caucasian, Chinese, and Vietnamese babies b...

journal_title：Journal of the American Academy of Dermatology

authors： Mar A,Tam M,Jolley D,Marks R

更新日期：1999-04-01 00:00:00

abstract：BACKGROUND:The pathologic evaluation of mycosis fungoides (MF) is a challenging area in dermatopathology. OBJECTIVE:We sought to determine the usefulness of flow cytometry for the diagnosis of MF from skin biopsy specimens. METHODS:Skin biopsy specimens from 22 patients with a clinical suggestion for MF were evaluate...

journal_title：Journal of the American Academy of Dermatology

authors： Oshtory S,Apisarnthanarax N,Gilliam AC,Cooper KD,Meyerson HJ

更新日期：2007-09-01 00:00:00

abstract：:Capecitabine, an oral fluoropyrimidine and 5-fluorouracil (FU) prodrug recently approved for the treatment of metastatic colon and breast cancer, is currently under investigation in patients with gastric cancer. It has the advantage of oral administration, and good tolerability with its activity being comparable with ...

journal_title：Journal of the American Academy of Dermatology

authors： Weger W,Kränke B,Gerger A,Salmhofer W,Aberer E

更新日期：2008-08-01 00:00:00

abstract：BACKGROUND:Indoor tanning may increase the risk of melanoma and other health problems. Frequent users of indoor tanning facilities may be at particularly high risk. OBJECTIVE:In study 1 our purpose was to assess the prevalence and nature of indoor tanning advertisements; in study 2 we aimed to assess tanning facility ...

journal_title：Journal of the American Academy of Dermatology

authors： Kwon HT,Mayer JA,Walker KK,Yu H,Lewis EC,Belch GE

更新日期：2002-05-01 00:00:00

abstract：:Longitudinal pigmentation of the nail is very common. The differential diagnosis varies from subungual hematoma, to a fungal infection, to a melanocytic lesion (lentigo, nevus melanoma, etc.) to others. Often, dermatologists do not feel at ease with these pathologies and management is often not clear. In many cases, a...

journal_title：Journal of the American Academy of Dermatology

authors： Braun RP,Baran R,Le Gal FA,Dalle S,Ronger S,Pandolfi R,Gaide O,French LE,Laugier P,Saurat JH,Marghoob AA,Thomas L

更新日期：2007-05-01 00:00:00

abstract：BACKGROUND:The enzyme indoleamine 2,3-dioxygenase (IDO) degrades the essential amino acid tryptophan, and this degradation is an immunosuppressive mechanism that is mainly used by antigen-presenting cells. IDO-expressing dendritic cells and macrophages have previously been identified as components of lymph node granulo...

journal_title：Journal of the American Academy of Dermatology

authors： von Bubnoff D,Scheler M,Wilms H,Wenzel J,von Bubnoff N,Häcker G,Schultze J,Popov A,Racz P,Bieber T,Wickenhauser C

更新日期：2011-10-01 00:00:00

abstract：:We report two cases in which dermatophytic infection developed almost entirely within a radiation field mimicking an acute radiation effect. Radiotherapists and dermatologists should be aware of this possibility and be able to differentiate it from radiation dermatitis. Topical antifungal agents are the recommended tr...

journal_title：Journal of the American Academy of Dermatology

authors： Rosen T,Dupuy J,Maor M,Altman A

更新日期：1988-12-01 00:00:00

abstract：:The PA Patch, a new multiple-antigen, predispensed patch testing device, was compared to the Finn Chamber in subjects with previous positive patch tests. After pressing the PA Patch well, the PA Patch performed as well as the Finn Chamber in nine subjects tested. ...

journal_title：Journal of the American Academy of Dermatology

authors： Marks JG Jr,Westheim A,Snipes W

更新日期：1987-05-01 00:00:00

abstract：BACKGROUND:Onychomycosis, a fungal infection of the nail bed, is responsible for up to 50% of nail disorders. Although several surveys have been conducted in different parts of the world, there have been no multicenter epidemiologic surveys of onychomycosis in North America. OBJECTIVE:A 12-center study was undertaken ...

journal_title：Journal of the American Academy of Dermatology

authors： Ghannoum MA,Hajjeh RA,Scher R,Konnikov N,Gupta AK,Summerbell R,Sullivan S,Daniel R,Krusinski P,Fleckman P,Rich P,Odom R,Aly R,Pariser D,Zaiac M,Rebell G,Lesher J,Gerlach B,Ponce-De-Leon GF,Ghannoum A,Warner J,Is

更新日期：2000-10-01 00:00:00

abstract：:A concept of dichotomous types of segmental involvement of autosomal dominant skin disorders has recently been proposed. Among the different types of porokeratosis, disseminated superficial actinic porokeratosis is known to be an autosomal dominant skin disorder, and linear porokeratosis represents the segmental form ...

journal_title：Journal of the American Academy of Dermatology

authors： Freyschmidt-Paul P,Hoffmann R,König A,Happle R

更新日期：1999-10-01 00:00:00

abstract：BACKGROUND:Gorlin-Goltz syndrome (GGS) is an autosomal-dominant disease characterized by the early onset of multiple basal cell carcinomas (BCCs), among other findings. Clinically, the BCCs may appear as soft pedunculated neoplasms that can be mistaken for true acrochordons. OBJECTIVE:We sought to describe the dermato...

journal_title：Journal of the American Academy of Dermatology

authors： Feito-Rodríguez M,Sendagorta-Cudós E,Moratinos-Martínez M,González-Beato MJ,de Lucas-Laguna R,Pizarro A

更新日期：2009-05-01 00:00:00

abstract：BACKGROUND:UVA induces tissue damage via the production of radical oxygen species. Adding antioxidants to UV filters in sunscreens is a novel photoprotective strategy. The topical application of antioxidants in sunscreen can potentially neutralize the UVA-induced free radicals. OBJECTIVES:We sought to assess the degre...

journal_title：Journal of the American Academy of Dermatology

authors： Wang SQ,Osterwalder U,Jung K

更新日期：2011-09-01 00:00:00

abstract：BACKGROUND:In several studies, delays in malignant melanoma (MM) diagnosis have been correlated with increased tumor thickness, increased morbidity, and increased mortality. OBJECTIVE:We sought to assess how MM is detected in British Columbia, Canada, and to understand the role of patient education and other factors o...

journal_title：Journal of the American Academy of Dermatology

authors： Tyler I,Rivers JK,Shoveller JA,Blum A

更新日期：2005-01-01 00:00:00

abstract：:A 52-year-old man with a history of melanoma presented to the emergency department with a massive intracranial hemorrhage. The patient deteriorated rapidly and was being considered as a potential organ donor. Three years before presentation, the patient had undergone wide excision of a 3.75-mm melanoma from his back w...

journal_title：Journal of the American Academy of Dermatology

authors： Cotter MA,Tristani-Firouzi P

更新日期：2006-06-01 00:00:00

abstract：:During 1 year of continuous suppressive therapy for frequent recurrent genital herpes, about 44% of patients taking 400 mg acyclovir twice a day had no recurrences and 4% of patients taking placebo had no recurrences (i.e., fewer patients taking acyclovir had recurrences, and when they did there were fewer recurrences...

journal_title：Journal of the American Academy of Dermatology

authors： Conant MA

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Focal atrichia is a common clinical finding in female pattern hair loss, the specificity and histologic findings of which need further clarification. OBJECTIVE:To determine the frequency of focal atrichia in various types of hair loss and its histologic characteristics in female pattern hair loss. METHODS:...

journal_title：Journal of the American Academy of Dermatology

authors： Olsen EA,Whiting DA

更新日期：2019-06-01 00:00:00

abstract：BACKGROUND:Pseudoxanthoma elasticum (PXE) is a systemic connective tissue disorder involving elastic fiber calcification and fragmentation with major clinical manifestations occurring in the cutaneous, ocular, and cardiovascular systems. Normalization of the serum calcium-phosphate product through hemodialysis in a pre...

journal_title：Journal of the American Academy of Dermatology

authors： Sherer DW,Singer G,Uribarri J,Phelps RG,Sapadin AN,Freund KB,Yanuzzi L,Fuchs W,Lebwohl M

更新日期：2005-10-01 00:00:00

abstract：BACKGROUND:Established data confirm an increased incidence of skin cancer, mainly squamous cell carcinoma (SCC), in long-term kidney transplant recipients (KTRs). OBJECTIVE:Our purpose was to investigate prospectively the type and frequency of neoplastic and preneoplastic skin lesions in KTRs during the first 3 years ...

journal_title：Journal of the American Academy of Dermatology

authors： Ferrándiz C,Fuente MJ,Ribera M,Bielsa I,Fernández MT,Lauzurica R,Roca J

更新日期：1995-10-01 00:00:00