Abstract：
:Topical photodynamic therapy (PDT) is used to treat nonmelanoma skin cancers, such as actinic keratoses, Bowen's disease, and basal cell carcinoma (superficial and nodular). This article presents up-to-date, practical, evidence-based recommendations on the use of topical PDT using 5-aminolevulinic acid or methyl aminolevulinate for the treatment (and prevention) of nonmelanoma skin cancers. A systematic literature review was conducted (using MEDLINE), and recommendations were made on the basis of the quality of evidence for efficacy, safety/tolerability, cosmetic outcome, and patient satisfaction/preference. Topical PDT is highly effective in the treatment of actinic keratoses, Bowen's disease, superficial and thin nodular basal cell carcinomas, with cosmesis typically superior to that achieved with existing standard therapies. PDT may also be a means of preventing certain nonmelanoma skin cancers in immunosuppressed patients.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Braathen LR,Szeimies RM,Basset-Seguin N,Bissonnette R,Foley P,Pariser D,Roelandts R,Wennberg AM,Morton CA,International Society for Photodynamic Therapy in Dermatology.doi
10.1016/j.jaad.2006.06.006subject
Has Abstractpub_date
2007-01-01 00:00:00pages
125-43issue
1eissn
0190-9622issn
1097-6787pii
S0190-9622(06)01718-Xjournal_volume
56pub_type
共识发展会议,杂志文章,实务指引abstract：BACKGROUND:For treatment of localized scleroderma numerous treatments, including ones with potentially hazardous side effects, are currently used with only limited success. OBJECTIVE:We attempted to determine the efficacy of low-dose UVA1 irradiation in patients with severe localized scleroderma. METHODS:Patients wer...
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