Unilateral trachyonychia in a patient with reflex sympathetic dystrophy.

abstract：BACKGROUND:Available information of the effect of sun exposure on the biologic activity and morphologic characteristics of nevi is based on a few cross-sectional studies. According to these, nevi excised in summer show a higher mitotic count, a greater extent of the junctional component, and more frequent regression an...

journal_title：Journal of the American Academy of Dermatology

authors： Stanganelli I,Rafanelli S,Bucchi L

更新日期：1996-03-01 00:00:00

abstract：:Both etretinate and its principal metabolite, acitretin, are efficacious in the treatment of psoriasis. Because patients with severe psoriasis often require chronic therapy, this study was undertaken to determine the efficacy, tolerability, and safety of acitretin in patients on continuous treatment for 12 months. The...

journal_title：Journal of the American Academy of Dermatology

authors： Murray HE,Anhalt AW,Lessard R,Schacter RK,Ross JB,Stewart WD,Geiger JM

更新日期：1991-04-01 00:00:00

abstract：BACKGROUND:Although most patients with cutaneous melanoma are non-Hispanic whites (NHWs), minorities consistently suffer worse melanoma-specific survival (MSS). Much of the literature comes from analyses of registries from the 1990s and 2000s. OBJECTIVE:We sought to evaluate whether and to what degree racial disparity...

journal_title：Journal of the American Academy of Dermatology

authors： Qian Y,Johannet P,Sawyers A,Yu J,Osman I,Zhong J

更新日期：2020-08-27 00:00:00

abstract：BACKGROUND:Many drugs have been used to treat scabies, but it is unclear which of them is the most efficacious. OBJECTIVE:To evaluate the comparative efficacy and safety of antiscabietic agents. METHODS:A systematic review of randomized controlled trials was conducted. Direct and network meta-analyses were applied to...

journal_title：Journal of the American Academy of Dermatology

authors： Thadanipon K,Anothaisintawee T,Rattanasiri S,Thakkinstian A,Attia J

更新日期：2019-05-01 00:00:00

abstract：BACKGROUND:The color, architecture, symmetry, and homogeneity (CASH) algorithm for dermoscopy includes a feature not used in prior algorithms, namely, architecture. Architectural order/disorder is derived from current concepts regarding the biology of benign versus malignant melanocytic neoplasms. OBJECTIVE:We sought ...

journal_title：Journal of the American Academy of Dermatology

authors： Henning JS,Dusza SW,Wang SQ,Marghoob AA,Rabinovitz HS,Polsky D,Kopf AW

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Epidermolysis bullosa (EB) is a family of 23 genetic skin disorders for which treatments are mainly supportive. Graftskin is a bilayered living human skin construct characterized by a normal expression profile of all the genes reported as mutant in EB. OBJECTIVE:The objective of this study was to evaluate t...

journal_title：Journal of the American Academy of Dermatology

authors： Fivenson DP,Scherschun L,Choucair M,Kukuruga D,Young J,Shwayder T

更新日期：2003-06-01 00:00:00

abstract：:Talimogene laherparepvec (T-VEC) is an oncolytic virus based on herpes simplex virus type 1 approved for intralesional treatment of advanced melanoma. In this article, we review the clinical literature on T-VEC for advanced melanoma and provide a practical approach to using T-VEC in the dermatologic surgery and oncolo...

journal_title：Journal of the American Academy of Dermatology

authors： Haitz K,Khosravi H,Lin JY,Menge T,Nambudiri VE

更新日期：2020-07-01 00:00:00

abstract：:A 65-year-old woman treated with etretinate for pityriasis rubra pilaris developed chronic active hepatitis. The elevated transaminases were noted 2 months after initiation of therapy and peaked 2 months after discontinuation of etretinate. The spectrum of liver toxicity induced by etretinate is reviewed. We suggest t...

journal_title：Journal of the American Academy of Dermatology

authors： Sanchez MR,Ross B,Rotterdam H,Salik J,Brodie R,Freedberg IM

更新日期：1993-05-01 00:00:00

abstract：:Vulvar melanosis is a condition in which intensely pigmented irregular macules, clinically mimicking malignant melanoma, appear on the vulva. A biopsy specimen shows only marked lower epidermal pigmentation without any melanocytic atypia or nesting. The process is benign, and reassurance is the only treatment. ...

journal_title：Journal of the American Academy of Dermatology

authors： Rudolph RI

更新日期：1990-11-01 00:00:00

abstract：:The diagnostic value of parakeratosis is reviewed, with special emphasis on associated inflammatory tissue reaction patterns and the geometric pattern of the scale. Parakeratosis may also occur in disorders not primarily inflammatory in nature and those associations are addressed. Topics are divided into 6 categories:...

journal_title：Journal of the American Academy of Dermatology

authors： Brady SP

更新日期：2004-01-01 00:00:00

abstract：BACKGROUND:Accurate evaluation of basal cell carcinoma (BCC) in the United States was not possible before the 2011 release of BCC-specific International Classification of Diseases, Ninth Revision, Clinical Modification codes. OBJECTIVE:We sought to describe BCC (including locally advanced BCC [LABCC]) incidence/preval...

journal_title：Journal of the American Academy of Dermatology

authors： Goldenberg G,Karagiannis T,Palmer JB,Lotya J,O'Neill C,Kisa R,Herrera V,Siegel DM

更新日期：2016-11-01 00:00:00

abstract：BACKGROUND:Desonide, a class 6 nonfluorinated topical corticosteroid, has been available for more than two decades. Hydrocortisone is widely used in the treatment of dermatoses in children. OBJECTIVE:Our purpose was to compare the safety and efficacy of desonide ointment and 1.0% hydrocortisone ointment in children wi...

journal_title：Journal of the American Academy of Dermatology

authors： Jorizzo J,Levy M,Lucky A,Shavin J,Goldberg G,Dunlap F,Hinds A,Strelka L,Baker M,Tuley M

更新日期：1995-07-01 00:00:00

abstract：:Chemical peeling, or chemexfoliation, has been used for centuries to improve signs of ultraviolet light-induced sun damage. Over the last 30 years, the science behind chemical peeling has evolved, increasing our understanding of the role of peeling ingredients and treatment indications. The depth of peels is directly ...

journal_title：Journal of the American Academy of Dermatology

authors： Lee KC,Wambier CG,Soon SL,Sterling JB,Landau M,Rullan P,Brody HJ,International Peeling Society.

更新日期：2019-08-01 00:00:00

abstract：BACKGROUND:Onychomycosis is observed less frequently in children than adults. Until recently management of onychomycosis in children included topical formulations, oral griseofulvin, and in some cases deferral of treatment. OBJECTIVE:We attempted to determine the prevalence of onychomycosis in North American children ...

journal_title：Journal of the American Academy of Dermatology

authors： Gupta AK,Sibbald RG,Lynde CW,Hull PR,Prussick R,Shear NH,De Doncker P,Daniel CR 3rd,Elewski BE

更新日期：1997-03-01 00:00:00

abstract：BACKGROUND:Dermatitis herpetiformis (DH) is highly associated with celiac disease. Recently, tissue transglutaminase (tTG) was identified as the autoantigen of IgA antibodies in celiac disease. The prevalence of antibodies to tTG in DH patients is not known. OBJECTIVE:The purpose of this study was to determine whether...

journal_title：Journal of the American Academy of Dermatology

authors： Rose C,Dieterich W,Bröcker EB,Schuppan D,Zillikens D

更新日期：1999-12-01 00:00:00

abstract：:A screening program for antiviral drugs begun at Burroughs Wellcome in the 1960s resulted in the discovery of acyclovir in 1974. Preclinical investigation brought the drug to clinical trials in 1977 and the first form of the drug (topical) was available to physicians in 1982. Activity of acyclovir is greatest against ...

journal_title：Journal of the American Academy of Dermatology

authors： King DH

更新日期：1988-01-01 00:00:00

abstract：BACKGROUND:Acral lentiginous melanomas compose a higher proportion of melanomas and have a higher mortality in ethnic minorities than in whites. Early detection by acral surface inspection during skin examinations may lead to improved acral lentiginous melanoma outcomes. OBJECTIVE:This study compared patient-reported ...

journal_title：Journal of the American Academy of Dermatology

authors： Tsai MS,Chiu MW

更新日期：2014-08-01 00:00:00

abstract：:A technique involving modification of the routine paraffin embedding procedure that allows immunohistochemical examination of extracellular antigens by light microscopy is described. The method is thus suitable for routine diagnostic immunofluorescence studies, permitting reliable, reproducible immunolabeling of immun...

journal_title：Journal of the American Academy of Dermatology

authors： Cerio R,MacDonald DM

更新日期：1988-10-01 00:00:00

abstract：BACKGROUND:Although dermatoscopy is widely used in Europe and Australia, little is known about dermatoscopy use by US dermatologists. OBJECTIVE:We sought to estimate the prevalence of dermatoscopy use by US dermatologists and examine associations with practice characteristics. METHODS:We conducted a cross-sectional s...

journal_title：Journal of the American Academy of Dermatology

authors： Engasser HC,Warshaw EM

更新日期：2010-09-01 00:00:00

abstract：:A newly recognized and well-described connective tissue disease, eosinophilia-myalgia syndrome, is thought to relate to L-tryptophan ingestion. The suspect L-tryptophan made in Japan has been distributed in Japan and in the United States. Different from many case reports of eosinophilia-myalgia syndrome in the United ...

journal_title：Journal of the American Academy of Dermatology

authors： Mizutani T,Mizutani H,Hashimoto K,Nakamura Y,Kishida M,Taniguchi H,Murata M,Kuzuhara S,Shimizu M

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:Early recognition of melanoma is the key in preventing metastatic disease. OBJECTIVE:The aim of this study was to evaluate diagnostic ability of general practitioners (GPs) and dermatologists concerning pigmented skin lesions in general and melanoma in particular. We also investigated whether the diagnostic...

journal_title：Journal of the American Academy of Dermatology

authors： Brochez L,Verhaeghe E,Bleyen L,Naeyaert JM

更新日期：2001-06-01 00:00:00

abstract：BACKGROUND:No large studies have defined the best treatment of actinic cheilitis. METHODS:We conducted a systematic review to define the best therapies for actinic cheilitis in clinical response and recurrences. RESULTS:We first identified 444 papers, and 49 were finally considered, including 789 patients and 843 tre...

journal_title：Journal of the American Academy of Dermatology

authors： Lai M,Pampena R,Cornacchia L,Pellacani G,Peris K,Longo C

更新日期：2020-09-01 00:00:00

abstract：BACKGROUND:Onychomycosis is an increasing problem with limited therapeutic options. OBJECTIVE:We evaluated the safety and efficacy, of oral terbinafine, a new fungicidal antimycotic, in patients with toenail onychomycosis. METHODS:A North American multicenter, double-blind, placebo-controlled study evaluated the myco...

journal_title：Journal of the American Academy of Dermatology

authors： Drake LA,Shear NH,Arlette JP,Cloutier R,Danby FW,Elewski BE,Garnis-Jones S,Giroux JM,Gratton D,Gulliver W,Hull P,Jones HE,Journet M,Krol AL,Leyden JJ,Maddin SC,Ross JB,Savin RC,Scher RK,Sibbald GR,Tawfik NH,Zaia

更新日期：1997-11-01 00:00:00

abstract：CAPSULE SUMMARY:In this article, we try to use the syringes without the piston part to control the amount of saline fluid in dermabrasion surgery. It is very convenient to obtain materials and simple to operate in skin surgery. ...

journal_title：Journal of the American Academy of Dermatology

authors： Cao C,Li H,Shao Z

更新日期：2020-10-10 00:00:00

abstract：:Hutchinson's sign, periungual extension of brown-black pigmentation from longitudinal melanonychia onto the proximal and lateral nailfolds, is an important indicator of subungual melanoma. However, experience has demonstrated that Hutchinson's sign, although valuable, is not an infallible predictor of melanoma. Periun...

journal_title：Journal of the American Academy of Dermatology

authors： Baran R,Kechijian P

更新日期：1996-01-01 00:00:00

abstract：BACKGROUND:Psoriasis and migraine are common conditions with potential overlap of pathophysiological mechanisms. Both these diseases have been associated with increased cardiovascular risk but little is known about their interplay. OBJECTIVE:We sought to investigate the link between psoriasis, and the risk of new-onse...

journal_title：Journal of the American Academy of Dermatology

authors： Egeberg A,Mallbris L,Hilmar Gislason G,Skov L,Riis Hansen P

更新日期：2015-11-01 00:00:00

abstract：BACKGROUND:Basal cell carcinoma (BCC) is a common skin cancer for which the treatment and recurrence risk correlate with the histologic subtype. Limited information is available regarding the accuracy of biopsy in diagnosing BCC subtypes. OBJECTIVE:We sought to determine the correlation between BCC subtypes present in...

journal_title：Journal of the American Academy of Dermatology

authors： Haws AL,Rojano R,Tahan SR,Phung TL

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:Calcipotriene and betamethasone dipropionate are topical treatments for psoriasis vulgaris. Their mode of action is different. Improved risk/benefit may result with concomitant use of the two compounds together. A new vehicle has been created with the objective of obtaining optimal stability of both calcipot...

journal_title：Journal of the American Academy of Dermatology

authors： Papp KA,Guenther L,Boyden B,Larsen FG,Harvima RJ,Guilhou JJ,Kaufmann R,Rogers S,van de Kerkhof PC,Hanssen LI,Tegner E,Burg G,Talbot D,Chu A

更新日期：2003-01-01 00:00:00

abstract：BACKGROUND:Although there is increased understanding of the alopecia areata (AA) pathogenesis based on studies in scalp tissues, little is known about its systemic profile. OBJECTIVE:To evaluate the blood proteomic signature of AA and determine biomarkers associated with increased disease severity. METHODS:In a cross...

journal_title：Journal of the American Academy of Dermatology

authors： Glickman JW,Dubin C,Renert-Yuval Y,Dahabreh D,Kimmel GW,Auyeung K,Estrada YD,Singer G,Krueger JG,Pavel AB,Guttman-Yassky E

更新日期：2021-02-01 00:00:00

abstract：:A new technic is described for more accurately checking the surgical margins of skin tumors removed by standard surgical excision. Vertical sections of surgical specimens represent check points of the margin only 7 microns thick. This means most of the surgical margin is not checked microscopically, allowing small tum...

journal_title：Journal of the American Academy of Dermatology

authors： Schultz BC,Roenigk HH Jr

更新日期：1982-10-01 00:00:00