Safety of dermatologic drugs used in pregnant patients with psoriasis and other inflammatory skin diseases.

abstract：BACKGROUND:Intraoperative pain during Mohs micrographic surgery (MMS) has not been characterized. However, many patients report postoperative pain on the day of MMS. OBJECTIVE:We sought to determine if patients experience pain during their MMS visit. METHODS:In phase I of this study, patients were asked to report int...

journal_title：Journal of the American Academy of Dermatology

authors： Connolly KL,Nehal KS,Dusza SW,Rossi AM,Lee EH

更新日期：2016-09-01 00:00:00

abstract：:Mutations in the cathepsin C gene have recently been detected in Papillon-Lefèvre syndrome (PLS). Until now, 5 cases with the late-onset variation of this disease have been reported in the literature. The genetic background of this type of PLS is still unknown. We describe a 46-year-old woman with late-onset transgred...

journal_title：Journal of the American Academy of Dermatology

authors： Pilger U,Hennies HC,Truschnegg A,Aberer E

更新日期：2003-11-01 00:00:00

abstract：BACKGROUND:Since the late 1970s clinical criteria for dysplastic melanocytic nevi (DMN) have been proposed and discussed. However, to our knowledge, no rigorous quantitative evaluation of the ability of examiners to agree on the gross morphologic features ascribed to DMN or atypical melanocytic lesions in general has b...

journal_title：Journal of the American Academy of Dermatology

authors： Barnhill RL,Roush GC,Ernstoff MS,Kirkwood JM

更新日期：1992-02-01 00:00:00

abstract：:The terminology of the specific dermatoses of pregnancy has become increasingly confusing, with several names in use for identical clinical disorders. On the basis of our own study of sixty-four patients and a review of the literature, we propose a simplified classification: (1) herpes gestationis (pemphigoid gestatio...

journal_title：Journal of the American Academy of Dermatology

authors： Holmes RC,Black MM

更新日期：1983-03-01 00:00:00

abstract：:We studied 20 Caucasian middle-aged patients, mostly women, who had asymptomatic, gray-brown patches with geographic borders, occasionally interspersed with hypopigmented macules, on the dorsum of the forearms, mostly bilaterally. The distal aspect of the arms was also involved in 2 patients; the face was always spare...

journal_title：Journal of the American Academy of Dermatology

authors： Rongioletti F,Rebora A

更新日期：2000-04-01 00:00:00

abstract：BACKGROUND:Fibrous hamartoma (FH) of infancy is a benign mesenchymal tumor, occurring as a superficial mass. Complete excision is curative. OBJECTIVE AND METHODS:The clinical features and treatment results of 18 children with FH are described. RESULTS:Local excision was the most common procedure. Surgery was radical ...

journal_title：Journal of the American Academy of Dermatology

authors： Carretto E,Dall'Igna P,Alaggio R,Siracusa F,Granata C,Ferrari A,Cecchetto G

更新日期：2006-05-01 00:00:00

abstract：BACKGROUND:Guselkumab, an interleukin-23 blocker, was superior to adalimumab in treating moderate to severe psoriasis in a phase II trial. OBJECTIVES:We sought to compare efficacy and safety of guselkumab with adalimumab and placebo in patients with psoriasis treated for 1 year. METHODS:Patients were randomized to gu...

journal_title：Journal of the American Academy of Dermatology

authors： Blauvelt A,Papp KA,Griffiths CE,Randazzo B,Wasfi Y,Shen YK,Li S,Kimball AB

更新日期：2017-03-01 00:00:00

abstract：BACKGROUND:We have observed, in patients undergoing high-dose PUVA treatment, a type of keratosis not previously described. The lesions usually occur on the sides of the palms or soles and are clinically distinct. They are generally painless and often go unnoticed by patients. OBJECTIVE:We sought to further characteri...

journal_title：Journal of the American Academy of Dermatology

authors： Turner RJ,Sviland L,Charlton F,Farr PM

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND:Trichoadenoma is a rare benign follicular tumor first described by Nikolowski 50 years ago. Both trichoadenoma and desmoplastic trichoepithelioma are composed of cords of epithelial cells and cornifying cysts embedded in sclerotic stroma. In trichoadenoma the cystic component predominates, while desmoplastic...

journal_title：Journal of the American Academy of Dermatology

authors： Shimanovich I,Krahl D,Rose C

更新日期：2010-02-01 00:00:00

abstract：BACKGROUND:The Patient-Reported Outcomes Measurement Information System (PROMIS) Itch Questionnaire (PIQ) was recently developed. OBJECTIVE:To validate PIQ short forms in adults with AD. METHODS:Self-administered questionnaires and skin examinations were performed in 239 adults with atopic dermatitis (AD) in a dermat...

journal_title：Journal of the American Academy of Dermatology

authors： Silverberg JI,Lai JS,Vakharia PP,Patel K,Singam V,Chopra R,Sacotte R,Patel N,Rastogi S,Kantor R,Hsu DY,Cella D

更新日期：2020-05-01 00:00:00

abstract：:We report a case of a neonate with a congenital tumor on the left palm. The patient had a grapefruit-sized tumor and coagulopathy at birth and was presumed to have a hemangioendothelioma with associated Kasabach-Merritt phenomenon. When the tumor failed to respond to systemic steroids, a biopsy specimen was taken, rev...

journal_title：Journal of the American Academy of Dermatology

authors： Asgari M,Rubin BP,Hornung RL

更新日期：2004-02-01 00:00:00

abstract：:Erythematous papulonodules that resembled a malignant lymphoma developed in a 62-year-old man. Further examination revealed that he had primary myelofibrosis with cutaneous extramedullary hematopoiesis. All three marrow elements (myeloid, erythroid, and megakaryocytic series) were present in the skin lesions. Although...

journal_title：Journal of the American Academy of Dermatology

authors： Mizoguchi M,Kawa Y,Minami T,Nakayama H,Mizoguchi H

更新日期：1990-02-01 00:00:00

abstract：BACKGROUND:The color, architecture, symmetry, and homogeneity (CASH) algorithm for dermoscopy includes a feature not used in prior algorithms, namely, architecture. Architectural order/disorder is derived from current concepts regarding the biology of benign versus malignant melanocytic neoplasms. OBJECTIVE:We sought ...

journal_title：Journal of the American Academy of Dermatology

authors： Henning JS,Dusza SW,Wang SQ,Marghoob AA,Rabinovitz HS,Polsky D,Kopf AW

更新日期：2007-01-01 00:00:00

abstract：:Thirty-two patients with acne completed a randomized, double-blind study using topical 1% clindamycin phosphate or its vehicle applied twice daily for 8 weeks for a study of its effects on the intestinal microflora. Two clindamycin patients and one vehicle patient had Clostridium difficile in stools prior to therapy. ...

journal_title：Journal of the American Academy of Dermatology

authors： Siegle RJ,Fekety R,Sarbone PD,Finch RN,Deery HG,Voorhees JJ

更新日期：1986-08-01 00:00:00

abstract：:As a wider variety of organisms are being identified in superficial fungal infections, more accurate methods of identification may be required to determine fungal susceptibility. The sensitivity of available methods, such as the minimal inhibitory concentration test, is reviewed. The sensitivities of causative pathoge...

journal_title：Journal of the American Academy of Dermatology

authors： Meinhof W

更新日期：1993-07-01 00:00:00

abstract：BACKGROUND:The reported efficacy of imiquimod for lentigo maligna varies widely, without consensus on tumor or treatment factors that can impact tumor clearance. OBJECTIVE:We sought to provide a more precise estimate of clearance rates in patients with lentigo maligna who are treated with imiquimod and to analyze fact...

journal_title：Journal of the American Academy of Dermatology

authors： Mora AN,Karia PS,Nguyen BM

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:It is unclear whether the type 2 T helper cell-specific immunosuppressive action of dupilumab interferes with patch testing. OBJECTIVES:We sought to evaluate the reliability of patch testing on dupilumab and the contribution of allergic contact dermatitis (ACD) to complex dermatitis in patients with residua...

journal_title：Journal of the American Academy of Dermatology

authors： Raffi J,Suresh R,Botto N,Murase JE

更新日期：2020-01-01 00:00:00

abstract：:Immunopathology continues to be important in diagnostic dermatopathology. Immunopathology is an invaluable tool for assessing the tissue of origin or direction of differentiation of cells. In some cases this can result in a more precise diagnosis. This article reviews the role of immunopathology in determining the bio...

journal_title：Journal of the American Academy of Dermatology

authors： Wallace ML,Smoller BR

更新日期：1996-02-01 00:00:00

abstract：BACKGROUND:Some clinicians perform cutaneous laser treatments through transparent membranes to protect themselves and the surroundings from contamination by ejected tissue particles. Transmissibility of these membranes influences the tissue irradiance. OBJECTIVE:We compared the optical transmissibility of 8 membranes....

journal_title：Journal of the American Academy of Dermatology

authors： Chen C,Diven DG,Lockhart S,Bell B

更新日期：2001-12-01 00:00:00

abstract：:Long-term penicillamine therapy has been associated with alterations in dermal elastic tissue. Well-described associated dermatoses include pseudo-pseudoxanthoma elasticum, acquired cutis laxa, elastosis perforans serpiginosa, and anetoderma. Histologically, "lumpy-bumpy" or "bramble-bush" morphologic changes of elast...

journal_title：Journal of the American Academy of Dermatology

authors： Lewis BK,Chern PL,Stone MS

更新日期：2009-04-01 00:00:00

abstract：UNLABELLED:Revolutionary advances in laser research and technology have led to expanded dermatologic laser applications. With the wide range of lasers now available, a large spectrum of skin conditions in the pediatric population can be successfully treated or, in some cases, completely eradicated. Laser treatment of t...

journal_title：Journal of the American Academy of Dermatology

authors： Cantatore JL,Kriegel DA

更新日期：2004-02-01 00:00:00

abstract：:The evaluation of skin findings is critical in identifying many types of injury, whether self- inflicted or accidentally or intentionally inflicted. Specific causes of injury include homicide, abuse, neglect, assault, self-inflicted injury, suicide, torture, poisoning, and bioterrorism. Forensic findings in hair and n...

journal_title：Journal of the American Academy of Dermatology

authors： Reddy K,Lowenstein EJ

更新日期：2011-05-01 00:00:00

abstract：:It has been demonstrated recently in mycosis fungoides and lichen planus that T lymphocyte subsets may be identified in cutaneous lymphocytic infiltrates using the immunoperoxidase technic in conjunction with monoclonal antibodies produced by the technic of Kohler and Milstein. This communication describes the applica...

journal_title：Journal of the American Academy of Dermatology

authors： McMillan EM,Wasik R,Everett MA

更新日期：1982-01-01 00:00:00

abstract：BACKGROUND:It is unclear whether patients with atopic dermatitis (AD) have an altered prevalence or risk for contact sensitization. Increased exposure to chemicals in topical products together with impaired skin barrier function suggest a higher risk, whereas the immune profile suggests a lower risk. OBJECTIVE:To perf...

journal_title：Journal of the American Academy of Dermatology

authors： Hamann CR,Hamann D,Egeberg A,Johansen JD,Silverberg J,Thyssen JP

更新日期：2017-07-01 00:00:00

abstract：UNLABELLED:Cyclosporine is highly effective in the treatment of a multitude of dermatoses. Concern over its side effect profile has limited its use in dermatology. Adverse effects are, for the most part, dose dependent and related to duration of therapy. Using the recommended monitoring protocols results in a significa...

journal_title：Journal of the American Academy of Dermatology

authors： Ryan C,Amor KT,Menter A

更新日期：2010-12-01 00:00:00

abstract：:Burow's wedge flap provides an excellent method for repair of wounds in or near the eyebrow. Advantages afforded by this technic in this context include ample flap elasticity and vascularization, versatility in dealing with wounds of varying dimension and location, and fewer incisions in comparison with the number nec...

journal_title：Journal of the American Academy of Dermatology

authors： Gormley DE

更新日期：1985-02-01 00:00:00

abstract：:Three young and middle-aged patients developed severe bullous eruption after receiving various penicillins. The clinical findings included high fever, prostration, widespread bullous eruption mainly on the head, face, and extremities, targetlike lesions on the palms and soles, and severe erosions in almost all the muc...

journal_title：Journal of the American Academy of Dermatology

authors： Alcalay J,David M,Ingber A,Hazaz B,Sandbank M

更新日期：1988-02-01 00:00:00

abstract：:Isotretinoin is used to treat severe and recalcitrant acne. Possible side effects include depression, suicide, and suicidal ideation; however, other studies suggest isotretinoin may improve mood and quality of life. Although iPLEDGE consenting warns about the risk of depression and suicidal ideation, there is no recom...

journal_title：Journal of the American Academy of Dermatology

authors： Schrom K,Nagy T,Mostow E

更新日期：2016-07-01 00:00:00

abstract：BACKGROUND:Acral vascular syndromes associated with malignancy have rarely been reported. OBJECTIVE:Our purpose was to assess the clinical and evolving features of paraneoplastic acral vascular syndromes. PATIENTS AND METHODS:Two cases of paraneoplastic gangrene are described and analyzed together with previously rep...

journal_title：Journal of the American Academy of Dermatology

authors： Poszepczynska-Guigné E,Viguier M,Chosidow O,Orcel B,Emmerich J,Dubertret L

更新日期：2002-07-01 00:00:00

abstract：:Linear IgA bullous dermatosis (LABD) is an autoimmune blistering skin disease characterized by circulating IgA antibodies binding the basement membrane zone. In most cases the origin is not clear, but in a minority of cases LABD is drug induced. We describe a patient in whom linear IgA disease developed shortly after ...

journal_title：Journal of the American Academy of Dermatology

authors： König C,Eickert A,Scharfetter-Kochanek K,Krieg T,Hunzelmann N

更新日期：2001-04-01 00:00:00