Abstract:
:Three patients with advanced atherosclerotic vascular disease developed multiple cholesterol emboli. The clinical presentation typically includes livedo reticularis of the lower part of the body and purple toes. Small areas of necrosis and ulceration may be present distally, despite palpable pulses. Muscular and abdominal pain, as well as alterations in renal function, may also occur. Cutaneous biopsy reveals characteristic cholesterol clefts within atheromatous debris filling small, deep arterial lumen. Pathophysiologic mechanisms are discussed.
journal_name
J Am Acad Dermatoljournal_title
Journal of the American Academy of Dermatologyauthors
Kalter DC,Rudolph A,McGavran Mdoi
10.1016/s0190-9622(85)70165-xsubject
Has Abstractpub_date
1985-08-01 00:00:00pages
235-42issue
2 Pt 1eissn
0190-9622issn
1097-6787pii
S0190-9622(85)70165-Xjournal_volume
13pub_type
杂志文章abstract:BACKGROUND:The focal facial dermal dysplasias (FFDD) are a genetically heterogeneous group of disorders characterized by congenital bilateral scarlike facial lesions, with or without associated facial anomalies. The cases have been reported under various names; thus the nosology is confusing and unclear. OBJECTIVE:Our...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/0190-9622(92)70225-5
更新日期:1992-10-01 00:00:00
abstract::We report a case of a neonate with a congenital tumor on the left palm. The patient had a grapefruit-sized tumor and coagulopathy at birth and was presumed to have a hemangioendothelioma with associated Kasabach-Merritt phenomenon. When the tumor failed to respond to systemic steroids, a biopsy specimen was taken, rev...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(03)01486-5
更新日期:2004-02-01 00:00:00
abstract::The effect of drug concentrations of 2.5%, 5%, and 10% upon the transepidermal penetration of 14C-benzoyl peroxide in a lotion vehicle was assessed in excised human skin and in vivo in the rhesus monkey. In vitro, penetration of benzoyl peroxide was concentration-dependent, both as to rate and to amount, as measured b...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(83)70209-4
更新日期:1983-12-01 00:00:00
abstract:BACKGROUND:Very few studies have focused on fat redistribution induced by corticosteroids. OBJECTIVE:To establish the incidence and risk factors of facial ("moon face") and cervical ("buffalo hump") lipodystrophy due to long-term (> or =3 months), high dosage (>or =20 mg/d) systemic corticosteroid therapy. METHODS:Be...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1016/j.jaad.2007.04.018
更新日期:2007-10-01 00:00:00
abstract:BACKGROUND:Onychomycosis (OM) affects up to 10% of the general population and is associated with functional impairment. Clinically, OM can mimic nail psoriasis, trauma, lichen planus, oncyhogryphosis, and other disorders. Laboratory methods for diagnosing OM vary in accuracy and predictive value. Clinical clues to OM w...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2006.06.003
更新日期:2007-06-01 00:00:00
abstract:BACKGROUND:Few studies have examined patients initially presenting with clinical features of urticarial dermatitis (UD). OBJECTIVE:We sought to examine clinical and laboratory evaluations and final diagnoses of patients with clinical features of UD. METHODS:This was a retrospective review of patients with UD seen at ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2013.08.050
更新日期:2014-02-01 00:00:00
abstract::Acute generalized exanthematous pustulosis is a severe cutaneous adverse reaction characterized by the rapid development of nonfollicular, sterile pustules on an erythematous base. It is attributed to drugs in the majority of cases. Antibiotics are the most common cause of acute generalized exanthematous pustulosis; h...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2015.07.017
更新日期:2015-11-01 00:00:00
abstract:BACKGROUND:Patients with pemphigus vulgaris (PV) are genetically linked to two alleles of the HLA subgroup, and circulating antibodies were found in first-degree relatives of these patients, thus showing genetic predisposition. OBJECTIVE:Our purpose was to determine the occurrence of circulating true PV-IgG in patient...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(97)70324-4
更新日期:1997-01-01 00:00:00
abstract:BACKGROUND:Often after biopsy a skin cancer appears to resolve clinically and a repeat biopsy may be done on the area in question before proceeding with further treatment. OBJECTIVE:Our purpose was to assess the value of a subsequent biopsy in the treatment of skin cancers previously diagnosed by biopsy results. METH...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(92)70159-d
更新日期:1992-07-01 00:00:00
abstract::Subungual Bowen's disease and squamous cell carcinoma are not as rare as has been implied by earlier literature. The course of the lesions is protracted. Clinically the diseases may mimic onychomycosis, chronic paronychia, eczema, verruca vulgaris, pyogenic granuloma, subungual exostosis, or malignant melanoma. Histol...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(84)70165-4
更新日期:1984-08-01 00:00:00
abstract::A new, quantitative modification of the vasoconstrictor assay was used to measure bioavailability of generic topical corticosteroid products in two categories: betamethasone valerate 0.1% cream and triamcinolone 0.1% cream. Betamethasone valerate products could be separated into two distinct categories, and triamcinol...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(89)70091-8
更新日期:1989-05-01 00:00:00
abstract::Vogt-Koyanagi-Harada disease is a rare disease characterized by uveitis, meningitis, dysacusis, alopecia, poliosis, and vitiligo. We describe a 48-year-old patient with Vogt-Koyanagi-Harada disease associated with thin inflammatory raised erythema and plaque-type inflammatory erythema superimposed on vitiligo. Interes...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1067/mjd.2001.110879
更新日期:2001-01-01 00:00:00
abstract::It is often stated that persons of Celtic origin have an increased risk of skin cancer, but the evidence for this is almost exclusively anecdotal. We believe that the possibility of the Celts being at greater risk of skin cancer has important implications with regard to management in particular and in assisting our un...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/0190-9622(95)91289-4
更新日期:1995-10-01 00:00:00
abstract:BACKGROUND:Dermatoscopy is the most commonly used noninvasive tool for the diagnosis of pigmented skin lesions, but few studies have investigated the value of cytology in the identification of those lesions. OBJECTIVE:We compared the accuracy of dermatoscopy with that of the Tzanck smear test in the diagnosis of pigme...
journal_title:Journal of the American Academy of Dermatology
pub_type: 临床试验,杂志文章
doi:10.1016/j.jaad.2010.08.019
更新日期:2011-11-01 00:00:00
abstract:BACKGROUND:Although etanercept is used as a continuous therapy for moderate to severe plaque psoriasis, intermittent use may be necessary in some instances. OBJECTIVE:In this randomized, open-label study, we evaluated the effectiveness and safety of continuous versus interrupted etanercept therapy. METHODS:All patien...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jaad.2006.09.002
更新日期:2007-04-01 00:00:00
abstract::Papular mucinosis is a rare, idiopathic cutaneous mucinosis that is typically chronic and progressively severe. We present a case of a 59-year-old woman with a 6-month history of a dramatic papular eruption on her face and neck, with no associated internal organ involvement. A biopsy specimen demonstrated increased de...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(03)00790-4
更新日期:2004-01-01 00:00:00
abstract::A tumor is reported that had remarkable pathologic changes showing with light microscopy a pattern in some portions consistent with tubular apocrine adenoma, while other areas were suggestive of syringoid eccrine carcinoma. Perineural invasion, commonly seen in syringoid eccrine carcinoma and never before reported in ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(84)70221-0
更新日期:1984-10-01 00:00:00
abstract:BACKGROUND:The autoantibody-mediated disease in fogo selvagem (FS) is aggravated by sunlight exposure. OBJECTIVE:The aim of this study was to test whether UVB exposure of uninvolved skin of patients with FS (n = 21) enhances epidermal acantholysis and in vivo binding of FS autoantibodies as compared with a control gro...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:
更新日期:2000-04-01 00:00:00
abstract::Four female patients with chromoblastomycosis were completely cured by prolonged topical application of tolerable heat from pocket warmers. The lesions involuted after 2, 3, and 6 months, respectively, in three patients who faithfully followed our strict treatment schedule, in contrast to the fourth patient who perfor...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(84)80266-2
更新日期:1984-04-01 00:00:00
abstract::Malignant myxoid melanoma (MMM) is a rarely reported variant of malignant melanoma, which can often be confused with other mucin-containing neoplasms. A retrospective study of 3 cases of MMM and a review of the English-language literature was performed. MMM affects an older population and is frequently misdiagnosed. T...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1067/mjd.2002.119650
更新日期:2002-02-01 00:00:00
abstract::Although sclerotherapy is an established procedure to treat ectatic veins, a wide disparity remains in the reported rates of success, especially for larger varicose veins. This article reviews the venous anatomy of the lower extremity and outlines the indications for sclerotherapy. The historical basis for treatment t...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/s0190-9622(98)70506-7
更新日期:1998-03-01 00:00:00
abstract::A young woman developed minocycline-related lupus erythematosus with associated autoimmune hepatitis. All clinical and laboratory abnormalities returned to normal when the drug was stopped. The symptoms worsened dramatically upon rechallenge, strongly suggesting the reaction was related to the minocycline. ...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(97)70043-4
更新日期:1997-05-01 00:00:00
abstract:BACKGROUND:The current standard tool for diagnosing allergic contact dermatitis (ACD) in the United States is the T.R.U.E. test panels, which consist of 23 allergens. Previous studies have raised concern regarding the adequacy of these panels in fully assessing patients with possible ACD. OBJECTIVE:We sought to examin...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1067/mjd.2003.489
更新日期:2003-07-01 00:00:00
abstract::A 39-year-ole man developed edema and vesiculation of the oral mucosa following the application of benzocaine (Hurricaine) gel. Open testing demonstrated an immediate urticarial reaction. Closed patch tests were positive after 48 hours. The contact dermatitis was consistent with a delayed-type hypersensitivity. It app...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(80)80009-0
更新日期:1980-03-01 00:00:00
abstract:BACKGROUND:Mycoplasma pneumoniae infection is associated with extrapulmonary complications, including mucocutaneous eruptions. These eruptions, which have been termed either "Stevens-Johnson syndrome" or "erythema multiforme" in the literature, may differ from drug-induced Stevens-Johnson syndrome or viral-associated e...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章,评审
doi:10.1016/j.jaad.2014.06.026
更新日期:2015-02-01 00:00:00
abstract::The Papillon-Lefèvre syndrome is characterized by palmoplantar hyperkeratosis and juvenile periodontitis that results in the precocious loss of both the deciduous and permanent teeth. We report a patient with Papillon-Lefèvre syndrome associated with acroosteolysis, an association that has not been previously describe...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/0190-9622(91)70127-n
更新日期:1991-05-01 00:00:00
abstract:BACKGROUND:Atopic dermatitis is a common multifactorial disease that seems to be increasing in frequency. OBJECTIVE:Our purpose was to determine the increased prevalence of atopic dermatitis in North Europe. METHODS:Approximately 3000 7-year-old children in Denmark, Germany, and Sweden were enrolled in a cross-sectio...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/s0190-9622(96)90009-2
更新日期:1996-05-01 00:00:00
abstract::Skin specimens from five mummies were examined histologically. The specimens ranged in age from 2,000 to 3,200 years. Material from two mummies had carbonized and showed only amorphous debris. The histology of the three remaining skin fragments retained surprising histologic architectural detail. One specimen obtained...
journal_title:Journal of the American Academy of Dermatology
pub_type: 历史文章,杂志文章
doi:10.1016/s0190-9622(81)70003-3
更新日期:1981-01-01 00:00:00
abstract::The pathogenesis of Fox-Fordyce disease has been reported to be hyperkeratosis and obstruction of the upper hair follicle, where the duct of the apocrine sweat gland opens. We report a case of Fox-Fordyce disease with full clinical manifestation. It appeared to be caused by the obstruction of intraepidermal apoeccrine...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1067/mjd.2003.93
更新日期:2003-03-01 00:00:00
abstract:BACKGROUND:The increasing use of biologics is accompanied by a risk of hepatitis B (HBV) and C virus (HCV) reactivation. OBJECTIVE:To determine the predictors of HBV and HCV reactivation in psoriasis patients receiving biologics. METHODS:This study screened 2060 psoriasis patients (3562 treatment episodes) who were t...
journal_title:Journal of the American Academy of Dermatology
pub_type: 杂志文章
doi:10.1016/j.jaad.2019.12.001
更新日期:2019-12-07 00:00:00