Annular elastolytic giant cell granuloma in an infant: improvement after treatment with oral tranilast and topical pimecrolimus.

abstract：BACKGROUND:Spironolactone is used off-label for androgenic alopecia because of its ability to arrest hair loss progression and long-term safety profile. However, little is known about the safety of spironolactone in breast cancer (BC) survivors. Because spironolactone has estrogenic effects, there is a theoretical risk...

journal_title：Journal of the American Academy of Dermatology

authors： Wei C,Bovonratwet P,Gu A,Moawad G,Silverberg JI,Friedman AJ

更新日期：2020-10-01 00:00:00

abstract：BACKGROUND:A discrimination between benign and malignant melanocytic lesions is not always possible by conventional histology. OBJECTIVE:Our purpose was to determine the proliferative activity in various types of melanocytic neoplasms and to appraise its value as a diagnostic adjunct. METHODS:The growth fraction was ...

journal_title：Journal of the American Academy of Dermatology

authors： Rudolph P,Schubert C,Schubert B,Parwaresch R

更新日期：1997-08-01 00:00:00

abstract：:Four cases of Laugier-Hunziker syndrome are described. In all patients (two men and two women between 39 and 57 years of age) pigmentation of the lower lip and hard palate was found. in addition, two patients had involvement of the buccal mucosa; another patient also had pigmentation of the upper lip, the gums, the so...

journal_title：Journal of the American Academy of Dermatology

authors： Veraldi S,Cavicchini S,Benelli C,Gasparini G

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:After oral intake, 5-methoxypsoralen (5-MOP) is as effective as 8-MOP for PUVA therapy for psoriasis, with a lower incidence of acute cutaneous side effects. OBJECTIVE:We compared bath-water delivery of 5-MOP and 8-MOP for photochemotherapy of psoriasis. METHODS:Twenty-two patients underwent phototesting w...

journal_title：Journal of the American Academy of Dermatology

authors： Calzavara-Pinton PG,Zane C,Carlino A,De Panfilis G

更新日期：1997-06-01 00:00:00

abstract：:Striking results were obtained with oral itraconazole therapy in two opportunistic mycoses. Of 28 patients with cryptococcal meningitis, 18 achieved complete responses, including 16 of 24 patients with acquired immunodeficiency syndrome. Other manifestations of cryptococcosis were similarly responsive. In aspergillosi...

journal_title：Journal of the American Academy of Dermatology

authors： Denning DW,Tucker RM,Hanson LH,Stevens DA

更新日期：1990-09-01 00:00:00

abstract：BACKGROUND:Treatment of Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) remains controversial. OBJECTIVE:We sought to evaluate the impact of cyclosporine on hospital mortality in patients with SJS/TEN. METHODS:All patients with SJS and TEN admitted to our center from 2011 to 2014 were treated unde...

journal_title：Journal of the American Academy of Dermatology

authors： Lee HY,Fook-Chong S,Koh HY,Thirumoorthy T,Pang SM

更新日期：2017-01-01 00:00:00

abstract：BACKGROUND:Cutaneous calcification is an acquired disorder whereby insoluble, amorphous calcium salts deposit in the skin. Classically, cutaneous calcification is categorized as metastatic, dystrophic, idiopathic, or iatrogenic. OBJECTIVE:The purpose of this study was to further elucidate the underlying pathogenic mec...

journal_title：Journal of the American Academy of Dermatology

authors： Pugashetti R,Shinkai K,Ruben BS,Grossman ME,Maldonado J,Fox LP

更新日期：2011-02-01 00:00:00

abstract：BACKGROUND:Glomangiomas are benign tumors arising from neuromyoarterial cells surrounding cutaneous arteriovenous anastomoses that serve as temperature regulators. They exist as solitary or multiple types, occurring sporadically or in a familial pattern, the latter of which is rare. OBJECTIVE:We describe a 4-generatio...

journal_title：Journal of the American Academy of Dermatology

authors： Blume-Peytavi U,Adler YD,Geilen CC,Ahmad W,Christiano A,Goerdt S,Orfanos CE

更新日期：2000-04-01 00:00:00

abstract：:A case of tuberculous skin ulcer is reported. The biopsy specimen did not reveal acid-fast bacteria but cultures grew Mycobacterium tuberculosis. A high index of suspicion is needed to diagnose mycobacterial ulcers correctly. The classification of the cutaneous tuberculoses is discussed. ...

journal_title：Journal of the American Academy of Dermatology

authors： Lantos G,Fisher BK,Contreras M

更新日期：1988-12-01 00:00:00

abstract：:A 4-year-old girl with failure to thrive and intense pruritus associated with Alagille syndrome is described. The clinical features of this autosomal dominant disorder are reviewed. This case highlights the importance of recognizing the severe pruritus as a manifestation of the disease. ...

journal_title：Journal of the American Academy of Dermatology

authors： Schwartz R,Rehder K,Parsons DJ,Morrell DS

更新日期：2008-02-01 00:00:00

abstract：:"Poikiloderma" is a morphologic and descriptive term referring to a combination of cutaneous atrophy, telangiectasia, and varied macular pigmentary changes that result in a mottled skin appearance. Its etiology includes both congenital and acquired causes. Many studies have reported different causes of acquired poikil...

journal_title：Journal of the American Academy of Dermatology

authors： Nofal A,Salah E

更新日期：2013-09-01 00:00:00

abstract：:We describe a female patient with an acute purpuric and bullous eruption mainly affecting the lower aspect of the legs. Skin biopsy specimens demonstrated microvascular occlusions with fibrin thrombi but no dermal inflammation. Intermediate hyperhomocysteinemia and transient antiphospholipid antibodies were evidenced ...

journal_title：Journal of the American Academy of Dermatology

authors： Martin L,Armingaud P,Georgescu V,Matre F,Legac E,Estève E

更新日期：2003-08-01 00:00:00

abstract：:The retinoids have been investigated extensively as chemopreventive and therapeutic agents in a variety of neoplasms. They have been shown to inhibit the proliferation of transformed cell lines in vitro and transplanted tumors in vivo. In cultured murine melanoma cells, retinoids inhibit proliferation and induce diffe...

journal_title：Journal of the American Academy of Dermatology

authors： Meyskens FL Jr,Edwards L,Levine NS

更新日期：1986-10-01 00:00:00

abstract：:The Cosmetic Ingredient Review (CIR) program was established in 1976 by the Cosmetics, Toiletry, and Fragrance Association, with the support of the Food and Drug Administration (FDA) and the Consumer Federation of America (CFA). CIR performs independent, expert reviews to determine if ingredients used in cosmetics are...

journal_title：Journal of the American Academy of Dermatology

authors： Bergfeld WF,Belsito DV,Marks JG Jr,Andersen FA

更新日期：2005-01-01 00:00:00

abstract：BACKGROUND:Few effective treatments are available for male pattern hair loss (MPHL) or, especially, for female pattern hair loss (FPHL). Recently, cell-based therapies using autologous or allogeneic cells have been used clinically. OBJECTIVE:We examined the safety and efficacy of autologous cell-based therapy using de...

journal_title：Journal of the American Academy of Dermatology

authors： Tsuboi R,Niiyama S,Irisawa R,Harada K,Nakazawa Y,Kishimoto J

更新日期：2020-07-01 00:00:00

abstract：:We report the case of an otherwise healthy 37-year-old man who had had bilateral enucleation during early childhood for bilateral retinoblastomas, in addition to two cutaneous melanomas (the first appearing at age 27 years). He also had dysplastic melanocytic nevi and a history of cutaneous melanoma in his mother. Ret...

journal_title：Journal of the American Academy of Dermatology

authors： Albert LS,Sober AJ,Rhodes AR

更新日期：1990-11-01 00:00:00

abstract：BACKGROUND:Genital or vulval lichen planus (VLP) may have a disabling effect on a patient's quality of life. Evidence-based management guidelines are lacking for VLP. OBJECTIVE:We sought to review clinical presentation and treatment of patients who received a diagnosis of VLP. METHODS:The 100 consecutive patients who...

journal_title：Journal of the American Academy of Dermatology

authors： Fahy CMR,Torgerson RR,Davis MDP

更新日期：2017-12-01 00:00:00

abstract：BACKGROUND:CD2- CD4+ CD56+ lymphoid malignancy has been only rarely reported the last 5 years. It is characterized by a high incidence of cutaneous involvement, cytologically agranular cells, aggressive clinical course, and negative Epstein-Barr virus (EBV) involvement. OBSERVATION:We describe a Japanese patient with ...

journal_title：Journal of the American Academy of Dermatology

authors： Kato N,Yasukawa K,Kimura K,Sugawara H,Aoyagi S,Mishina T,Nakata T

更新日期：2001-02-01 00:00:00

abstract：:A 65-year-old woman treated with etretinate for pityriasis rubra pilaris developed chronic active hepatitis. The elevated transaminases were noted 2 months after initiation of therapy and peaked 2 months after discontinuation of etretinate. The spectrum of liver toxicity induced by etretinate is reviewed. We suggest t...

journal_title：Journal of the American Academy of Dermatology

authors： Sanchez MR,Ross B,Rotterdam H,Salik J,Brodie R,Freedberg IM

更新日期：1993-05-01 00:00:00

abstract：:A tense yellow vesicle was noted on the back parietal scalp of a female newborn. This proved to be a bullous variant of aplasia cutis congenita. Only 16 cases of this apparently rare disorder have been previously reported. Histologic evaluation of such lesions reveals a distinct pattern containing fibrovascular stroma...

journal_title：Journal of the American Academy of Dermatology

authors： Colon-Fontanez F,Fallon Friedlander S,Newbury R,Eichenfield LF

更新日期：2003-05-01 00:00:00

abstract：BACKGROUND:Among the papular-pruriginous dermatoses related to human immunodeficiency (HIV) infection, two entities remain poorly differentiated leading to confusion in their diagnosis: HIV-related pruritic papular eruption (HIV-PPE or prurigo) and eosinophilic folliculitis (HIV-EF). OBJECTIVE:To establish histopathol...

journal_title：Journal of the American Academy of Dermatology

authors： Afonso JP,Tomimori J,Michalany NS,Nonogaki S,Porro AM

更新日期：2012-08-01 00:00:00

abstract：BACKGROUND:Vitiligo is an autoimmune disease of the skin with limited treatment options; there is an urgent need to identify and validate biomarkers of disease activity to support vitiligo clinical studies. OBJECTIVE:To investigate potential biomarkers of disease activity directly in the skin of vitiligo subjects and ...

journal_title：Journal of the American Academy of Dermatology

authors： Strassner JP,Rashighi M,Ahmed Refat M,Richmond JM,Harris JE

更新日期：2017-05-01 00:00:00

abstract：:A 16-year-old male patient had multiple angiokeratotic lesions arranged in a linear pattern on his left arm. Histopathologic examination showed characteristic features of verrucous hemangioma. This entity should be distinguished from angiokeratoma or simple hemangioma. The linear arrangement of lesions as observed in ...

journal_title：Journal of the American Academy of Dermatology

authors： Wentscher U,Happle R

更新日期：2000-03-01 00:00:00

abstract：:A 46-year-old white man had classic findings of scleredema; subsequently, a monoclonal immunoglobulin G lambda light chain was detected in his serum. Findings of a bone marrow biopsy specimen revealed that he had an increased percentage of plasma cells, some of which were atypical. A diagnosis of scleredema and smolde...

journal_title：Journal of the American Academy of Dermatology

authors： Schmidt KT,Gattuso P,Messmore H,Shrit MA,Massa M,Welykyj S

更新日期：1992-02-01 00:00:00

abstract：:Diabetic dermopathy (DD) is the most common cutaneous manifestation of diabetes mellitus. DD refers to atrophic, hyperpigmented macules characteristically located on the shins of patients with diabetes. They have an unfavorable association with the 3 most common microangiopathic complications of diabetes mellitus: neu...

journal_title：Journal of the American Academy of Dermatology

authors： Morgan AJ,Schwartz RA

更新日期：2008-03-01 00:00:00

abstract：:Direct immunofluorescence microscopy was positive in 88% of forty-one skin biopsy specimens from thirty-four patients with the clinical diagnosis of erythema multiforme. The most common finding, present in 67% of positive specimens, was the cytoid body, or fluorescent keratinocyte, which stained most often with IgM (h...

journal_title：Journal of the American Academy of Dermatology

authors： Finan MC,Schroeter AL

更新日期：1984-03-01 00:00:00

abstract：BACKGROUND:Clinical and histopathologic features of childhood melanoma are poorly characterized. Atypical clinical presentations and ambiguous microscopic findings may contribute to diagnostic delays. OBJECTIVES:We sought to determine whether conventional ABCDE melanoma detection criteria (Asymmetry, Border irregulari...

journal_title：Journal of the American Academy of Dermatology

authors： Cordoro KM,Gupta D,Frieden IJ,McCalmont T,Kashani-Sabet M

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Cutaneous leishmaniasis (CL) is caused by different species of Leishmania and transmitted by the bite of infected sand flies. It is a health problem in many countries. OBJECTIVE:This study was performed to assess the evidence for the efficacy of different therapeutic modalities for acute Old World CL, which...

journal_title：Journal of the American Academy of Dermatology

authors： Khatami A,Firooz A,Gorouhi F,Dowlati Y

更新日期：2007-08-01 00:00:00

abstract：BACKGROUND:Dermatoscopy is the most commonly used noninvasive tool for the diagnosis of pigmented skin lesions, but few studies have investigated the value of cytology in the identification of those lesions. OBJECTIVE:We compared the accuracy of dermatoscopy with that of the Tzanck smear test in the diagnosis of pigme...

journal_title：Journal of the American Academy of Dermatology

authors： Durdu M,Baba M,Seçkin D

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:The eruptive appearance of numerous seborrheic keratoses, the sign of Leser-Trélat, has been regarded as a reliable cutaneous marker of internal malignancy. OBJECTIVE:We have evaluated the possible association of malignant disease and the sign in 1752 consecutive cases of seborrheic keratoses. METHODS:Firs...

journal_title：Journal of the American Academy of Dermatology

authors： Lindelöf B,Sigurgeirsson B,Melander S

更新日期：1992-06-01 00:00:00