Neutrophilic dermatosis with myelodysplastic syndrome: nuclear segmentation anomalies of neutrophils in the skin lesion and in peripheral blood.

Abstract:

:Neutrophilic dermatosis developed in two patients with myelodysplastic syndrome. Biopsy specimens of their skin lesions showed marked infiltration by neutrophils with nuclear anomalies, that is, hyposegmentation (pseudo-Pelger-Huët anomaly) or hypersegmentation. Peripheral blood and bone marrow neutrophils had similar anomalies. To our knowledge, this is the first report of nuclear segmentation anomalies of neutrophils in neutrophilic dermatosis skin lesions of patients with myelodysplastic syndrome.

journal_name

J Am Acad Dermatol

authors

Morioka N,Otsuka F,Nogita T,Igisu K,Urabe A,Ishibashi Y

doi

10.1016/0190-9622(90)70206-w

subject

Has Abstract

pub_date

1990-08-01 00:00:00

pages

247-9

issue

2 Pt 1

eissn

0190-9622

issn

1097-6787

pii

0190-9622(90)70206-W

journal_volume

23

pub_type

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